HRP20030559A2 - Stabilized brivudine topical formulations containing metal oxide pigments - Google Patents

Stabilized brivudine topical formulations containing metal oxide pigments Download PDF

Info

Publication number
HRP20030559A2
HRP20030559A2 HR20030559A HRP20030559A HRP20030559A2 HR P20030559 A2 HRP20030559 A2 HR P20030559A2 HR 20030559 A HR20030559 A HR 20030559A HR P20030559 A HRP20030559 A HR P20030559A HR P20030559 A2 HRP20030559 A2 HR P20030559A2
Authority
HR
Croatia
Prior art keywords
brivudine
iron oxide
oxide
titanium dioxide
pharmaceutical preparation
Prior art date
Application number
HR20030559A
Other languages
English (en)
Croatian (hr)
Inventor
Gehlert Ulrike
Gr�ger Karsten
Schmitz Reinhard
Schrader Karl-Heinz
Schrader Andreas
Wihsmann Mare
Carlo
Manzini Stefano
Stubinski Bettina
Original Assignee
Menarini Ricerche S.P.A. Berlin-Chemie Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche S.P.A. Berlin-Chemie Ag filed Critical Menarini Ricerche S.P.A. Berlin-Chemie Ag
Publication of HRP20030559A2 publication Critical patent/HRP20030559A2/hr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
    • A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HR20030559A 2001-01-17 2002-01-10 Stabilized brivudine topical formulations containing metal oxide pigments HRP20030559A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01100968 2001-01-17
PCT/EP2002/000163 WO2002056913A2 (en) 2001-01-17 2002-01-10 Stabilized brivudine topical formulations containing metal oxide pigments

Publications (1)

Publication Number Publication Date
HRP20030559A2 true HRP20030559A2 (en) 2005-06-30

Family

ID=8176229

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20030559A HRP20030559A2 (en) 2001-01-17 2002-01-10 Stabilized brivudine topical formulations containing metal oxide pigments

Country Status (28)

Country Link
US (1) US20040087602A1 (cs)
EP (1) EP1365772A2 (cs)
JP (1) JP2004519460A (cs)
KR (1) KR20030070109A (cs)
CN (1) CN1236777C (cs)
AR (1) AR035530A1 (cs)
AU (1) AU2002244642B2 (cs)
BG (1) BG107988A (cs)
BR (1) BR0206478A (cs)
CA (1) CA2434743A1 (cs)
CZ (1) CZ20031912A3 (cs)
EE (1) EE200300322A (cs)
HR (1) HRP20030559A2 (cs)
HU (1) HUP0302741A3 (cs)
IL (1) IL156933A0 (cs)
MA (1) MA26266A1 (cs)
MX (1) MXPA03006307A (cs)
MY (1) MY136633A (cs)
NO (1) NO20033206L (cs)
PE (1) PE20020818A1 (cs)
PL (1) PL365741A1 (cs)
RU (1) RU2280453C2 (cs)
SK (1) SK8992003A3 (cs)
TN (1) TNSN03036A1 (cs)
UA (1) UA80673C2 (cs)
WO (1) WO2002056913A2 (cs)
YU (1) YU57103A (cs)
ZA (1) ZA200305437B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005046769A1 (de) * 2005-09-29 2007-04-05 Berlin-Chemie Ag Lichtstabile, brivudinhaltige pharmazeutische Formulierung zur Behandlung von Augenherpes (Herpes Ophthalmicus)
FR2936706B1 (fr) * 2008-10-08 2010-12-17 Oreal Composition cosmetique contenant un derive de dibenzoylmethane et un compose dithiolane ; procede de photostabilisation du derive de dibenzoylmethane
KR20110117133A (ko) * 2009-01-29 2011-10-26 다이닛본 스미토모 세이야꾸 가부시끼가이샤 내핵을 갖는 구강 내 붕괴 정
BR112017019920B1 (pt) * 2015-03-19 2023-11-07 Daiichi Sankyo Company, Limited Preparação sólida farmacêutica, e, método para estabilização de uma preparação sólida farmacêutica
CN104988791A (zh) * 2015-06-25 2015-10-21 广东义晟实业有限公司 一种抗病毒添加剂及添加该添加剂的胶水和uv漆

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0072137A1 (en) * 1981-08-01 1983-02-16 Beecham Group Plc Antiviral deoxyuridine compounds
HU196038B (en) * 1987-08-07 1988-09-28 Mta Koezponti Kemiai Kutato In Process for producing antiherpetic pharmaceutics for external use, containing 5-isopropyl-2'-beta-deoxy-uridine
DE4122337A1 (de) * 1991-07-05 1993-01-14 Cedona Pharm Bv Pharmazeutische zubereitung
FR2737118B1 (fr) * 1995-07-28 1997-09-05 Oreal Composition dermatologique ou pharmaceutique, procede de preparation et utilisation
GB9521454D0 (en) * 1995-10-19 1995-12-20 Kappa Pharmaceuticals Ltd Compositions for the treatment of conditions caused by herpes virus
US6558710B1 (en) * 1999-06-14 2003-05-06 Helen Rebecca Godfrey Topical zinc compositions and methods of use
DE10162593A1 (de) * 2001-12-19 2003-07-03 Menarini Ricerche Spa Stabilisierte topische Brivudin-Formulierungen

Also Published As

Publication number Publication date
BG107988A (bg) 2004-09-30
AU2002244642B2 (en) 2005-12-15
KR20030070109A (ko) 2003-08-27
UA80673C2 (en) 2007-10-25
ZA200305437B (en) 2004-07-15
WO2002056913A3 (en) 2002-11-07
EE200300322A (et) 2003-10-15
MA26266A1 (fr) 2004-09-01
TNSN03036A1 (en) 2005-04-08
HUP0302741A2 (hu) 2003-11-28
RU2003121639A (ru) 2005-02-10
CA2434743A1 (en) 2002-07-25
BR0206478A (pt) 2003-12-30
RU2280453C2 (ru) 2006-07-27
WO2002056913A2 (en) 2002-07-25
PE20020818A1 (es) 2002-10-21
HUP0302741A3 (en) 2007-06-28
IL156933A0 (en) 2004-02-08
JP2004519460A (ja) 2004-07-02
AR035530A1 (es) 2004-06-02
PL365741A1 (en) 2005-01-10
MXPA03006307A (es) 2003-09-16
CN1486185A (zh) 2004-03-31
NO20033206D0 (no) 2003-07-15
EP1365772A2 (en) 2003-12-03
CZ20031912A3 (cs) 2004-01-14
CN1236777C (zh) 2006-01-18
NO20033206L (no) 2003-07-15
SK8992003A3 (en) 2003-11-04
YU57103A (sh) 2006-08-17
US20040087602A1 (en) 2004-05-06
MY136633A (en) 2008-11-28

Similar Documents

Publication Publication Date Title
JP3661707B2 (ja) 皮膚外用剤
RS57103B1 (sr) Supstituisani derivati piridina korisni kao inhibitori c-fms kinaze
CN101808639A (zh) 抗真菌医药组合物
WO2004016238A1 (ja) 老化防止用組成物
SI9300469A (en) Antivirally active pharmaceutical oil-in-water emulsion containing 9-((2-hydroxyethoxy)methyl)guanine (acyclovir) or salt or ester thereof
HRP20030559A2 (en) Stabilized brivudine topical formulations containing metal oxide pigments
JPH05124925A (ja) メラニン生成抑制外用剤
JP2003176217A (ja) 皮膚外用剤
JPS61215318A (ja) 皮膚外用剤
AU2002244642A1 (en) Stabilized brivudine topical formulations containing metal oxide pigments
KR101425902B1 (ko) 하이드록삼산 유도체를 포함하는 피부 미백용 화장료 조성물
JPH05124924A (ja) メラニン生成抑制外用剤
JP2007176934A (ja) 血小板活性化因子アセチルヒドロラーゼ機能調整剤
NZ205587A (en) Composition comprising undecylenic acid for treating herpes simplex i
JPH05124923A (ja) メラニン生成抑制外用剤
HU196038B (en) Process for producing antiherpetic pharmaceutics for external use, containing 5-isopropyl-2'-beta-deoxy-uridine
JP2006516613A (ja) 単純疱疹の予防的治療のための調合物
JPH05124947A (ja) メラニン生成抑制外用剤
KR101438376B1 (ko) ｐＨ 조절을 통해 안정화된 프룩토오스 1,6-디포스페이트 화합물을 함유하는 피부 외용제 조성물
JP6727781B2 (ja) 乳化組成物
JPS60188306A (ja) 化粧料
JPH09507845A (ja) 皮膚炎を治療するための２，３−ジアリル−１−ベンゾピラン
JPH05124922A (ja) メラニン生成抑制外用剤
JPH05124948A (ja) メラニン生成抑制外用剤
JP3746986B2 (ja) 美白剤および美白用皮膚外用剤

Legal Events

Date Code Title Description
A1OB Publication of a patent application
AIPI Request for the grant of a patent on the basis of a substantive examination of a patent application
ODRP Renewal fee for the maintenance of a patent

Payment date: 20061229

Year of fee payment: 6

ODBI Application refused