ZA200406751B - Medicaments containing steroids and a novel anticholinesterase drug - Google Patents

Medicaments containing steroids and a novel anticholinesterase drug Download PDF

Info

Publication number: ZA200406751B
Authority: ZA; South Africa
Prior art keywords: inhalable; propellant; pharmaceutical composition; composition according; contain
Prior art date: 2002-04-12

Application number

ZA200406751A

Other languages

English (en)

Inventor

Banholzer Rolf

Meissner Helmut

Pairet Michel

Pohl Gerald

Speck Georg

Christopher John Montague Meade

Morschhouser Gerd

Michael P Pieper

Reichl Richard

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-04-12

Filing date

2004-08-25

Publication date

2006-12-27

2004-08-25 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2006-12-27 Publication of ZA200406751B publication Critical patent/ZA200406751B/en

Links

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239000003814 drug Substances 0.000 title claims description 5
239000000544 cholinesterase inhibitor Substances 0.000 title 1
239000013543 active substance Substances 0.000 claims description 44
239000000443 aerosol Substances 0.000 claims description 42
239000000203 mixture Substances 0.000 claims description 41
239000008194 pharmaceutical composition Substances 0.000 claims description 33
239000000546 pharmaceutical excipient Substances 0.000 claims description 25
238000009472 formulation Methods 0.000 claims description 24
239000004615 ingredient Substances 0.000 claims description 23
239000003380 propellant Substances 0.000 claims description 23
239000000843 powder Substances 0.000 claims description 21
150000003839 salts Chemical class 0.000 claims description 20
239000000725 suspension Substances 0.000 claims description 17
238000002360 preparation method Methods 0.000 claims description 14
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CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 claims description 9
239000002253 acid Substances 0.000 claims description 9
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 claims description 8
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UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims description 2
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GFNANZIMVAIWHM-OBYCQNJPSA-N triamcinolone Chemical compound O=C1C=C[C@]2(C)[C@@]3(F)[C@@H](O)C[C@](C)([C@@]([C@H](O)C4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 GFNANZIMVAIWHM-OBYCQNJPSA-N 0.000 claims description 2
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Classifications

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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
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- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Dispersion Chemistry (AREA)
Physical Education & Sports Medicine (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Steroid Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ZA200406751A 2002-04-12 2004-08-25 Medicaments containing steroids and a novel anticholinesterase drug ZA200406751B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10216429A DE10216429A1 (de)	2002-04-12	2002-04-12	Arzneimittel enthaltend Steroide und ein neues Anticholinergikum

Publications (1)

Publication Number	Publication Date
ZA200406751B true ZA200406751B (en)	2006-12-27

Family

ID=28458802

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200406751A ZA200406751B (en)	2002-04-12	2004-08-25	Medicaments containing steroids and a novel anticholinesterase drug

Country Status (29)

Country	Link
EP (2)	EP1496902B1 (fr)
JP (1)	JP4559086B2 (fr)
KR (1)	KR101010869B1 (fr)
CN (1)	CN1646126A (fr)
AR (1)	AR039275A1 (fr)
AT (1)	ATE312607T1 (fr)
AU (1)	AU2003216921B2 (fr)
BR (1)	BR0309085A (fr)
CA (1)	CA2481268C (fr)
DE (2)	DE10216429A1 (fr)
DK (1)	DK1496902T3 (fr)
EA (1)	EA008386B1 (fr)
EC (1)	ECSP045355A (fr)
ES (1)	ES2254917T3 (fr)
HR (1)	HRP20040943B1 (fr)
IL (2)	IL164391A0 (fr)
ME (1)	MEP54208A (fr)
MX (1)	MXPA04009917A (fr)
MY (1)	MY137045A (fr)
NO (1)	NO20044097L (fr)
NZ (1)	NZ536284A (fr)
PE (1)	PE20040326A1 (fr)
PL (1)	PL211227B1 (fr)
RS (1)	RS50776B (fr)
TW (1)	TWI311055B (fr)
UA (1)	UA80125C2 (fr)
UY (1)	UY27758A1 (fr)
WO (1)	WO2003086399A1 (fr)
ZA (1)	ZA200406751B (fr)

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WO2002088167A1 (fr)	2001-04-30	2002-11-07	Glaxo Group Limited	Derives anti-inflammatoires d'androstane 17.beta.-carbothioate ester avec un groupe cyclique en position 17.alpha
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AU2005210085B2 (en)	2004-02-06	2010-06-24	Meda Pharma Gmbh & Co. Kg	The combination of anticholinergics and glucocorticoids for the long-term treatment of asthma and COPD
EP2100599A1 (fr)	2008-03-13	2009-09-16	Laboratorios Almirall, S.A.	Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
EP2100598A1 (fr)	2008-03-13	2009-09-16	Laboratorios Almirall, S.A.	Composition à inhaler comprenant aclidinium pour le traitement de l'asthme et de maladies respiratoires obstructives chroniques
AU2010253770B9 (en)	2009-05-29	2015-02-12	Pearl Therapeutics, Inc.	Compositions for respiratory delivery of active agents and associated methods and systems
US8815258B2 (en)	2009-05-29	2014-08-26	Pearl Therapeutics, Inc.	Compositions, methods and systems for respiratory delivery of two or more active agents
EP2510928A1 (fr)	2011-04-15	2012-10-17	Almirall, S.A.	Aclidinium pour l'amélioration du sommeil des patients avec des maldadies respiratoires
US20140275517A1 (en)	2013-03-15	2014-09-18	Pearl Therapeutics, Inc.	Methods and systems for conditioning of particulate crystalline materials
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2002
- 2002-04-12 DE DE10216429A patent/DE10216429A1/de not_active Withdrawn
2003
- 2003-04-09 DK DK03712137T patent/DK1496902T3/da active
- 2003-04-09 PL PL371561A patent/PL211227B1/pl not_active IP Right Cessation
- 2003-04-09 EP EP03712137A patent/EP1496902B1/fr not_active Expired - Lifetime
- 2003-04-09 MX MXPA04009917A patent/MXPA04009917A/es active IP Right Grant
- 2003-04-09 EP EP05109887A patent/EP1621197A3/fr not_active Withdrawn
- 2003-04-09 AU AU2003216921A patent/AU2003216921B2/en not_active Expired
- 2003-04-09 CN CNA038083299A patent/CN1646126A/zh active Pending
- 2003-04-09 NZ NZ536284A patent/NZ536284A/en not_active IP Right Cessation
- 2003-04-09 RS YUP-899/04A patent/RS50776B/sr unknown
- 2003-04-09 WO PCT/EP2003/003668 patent/WO2003086399A1/fr not_active Ceased
- 2003-04-09 DE DE50301934T patent/DE50301934D1/de not_active Expired - Lifetime
- 2003-04-09 ME MEP-542/08A patent/MEP54208A/xx unknown
- 2003-04-09 KR KR1020047016335A patent/KR101010869B1/ko not_active Expired - Fee Related
- 2003-04-09 CA CA2481268A patent/CA2481268C/fr not_active Expired - Lifetime
- 2003-04-09 EA EA200401303A patent/EA008386B1/ru not_active IP Right Cessation
- 2003-04-09 HR HRP20040943AA patent/HRP20040943B1/hr not_active IP Right Cessation
- 2003-04-09 IL IL16439103A patent/IL164391A0/xx unknown
- 2003-04-09 AT AT03712137T patent/ATE312607T1/de active
- 2003-04-09 JP JP2003583418A patent/JP4559086B2/ja not_active Expired - Lifetime
- 2003-04-09 AR ARP030101241A patent/AR039275A1/es unknown
- 2003-04-09 BR BR0309085-0A patent/BR0309085A/pt not_active IP Right Cessation
- 2003-04-09 ES ES03712137T patent/ES2254917T3/es not_active Expired - Lifetime
- 2003-04-10 PE PE2003000365A patent/PE20040326A1/es not_active Application Discontinuation
- 2003-04-10 MY MYPI20031320A patent/MY137045A/en unknown
- 2003-04-10 TW TW092108227A patent/TWI311055B/zh not_active IP Right Cessation
- 2003-04-10 UY UY27758A patent/UY27758A1/es not_active Application Discontinuation
- 2003-09-04 UA UA20041109192A patent/UA80125C2/uk unknown
2004
- 2004-08-25 ZA ZA200406751A patent/ZA200406751B/en unknown
- 2004-09-27 NO NO20044097A patent/NO20044097L/no not_active Application Discontinuation
- 2004-10-04 IL IL164391A patent/IL164391A/en not_active IP Right Cessation
- 2004-10-11 EC EC2004005355A patent/ECSP045355A/es unknown

Also Published As

Publication number	Publication date
CN1646126A (zh)	2005-07-27
PL211227B1 (pl)	2012-04-30
ECSP045355A (es)	2005-01-28
RS50776B (sr)	2010-08-31
TW200403062A (en)	2004-03-01
MEP54208A (en)	2011-05-10
EP1621197A3 (fr)	2010-01-06
AU2003216921A1 (en)	2003-10-27
EA008386B1 (ru)	2007-04-27
MY137045A (en)	2008-12-31
ATE312607T1 (de)	2005-12-15
KR101010869B1 (ko)	2011-01-26
DK1496902T3 (da)	2006-05-08
KR20050000391A (ko)	2005-01-03
EP1496902B1 (fr)	2005-12-14
HRP20040943A2 (en)	2005-04-30
RS89904A (sr)	2006-10-27
WO2003086399A1 (fr)	2003-10-23
TWI311055B (en)	2009-06-21
PE20040326A1 (es)	2004-07-13
DE50301934D1 (de)	2006-01-19
EP1496902A1 (fr)	2005-01-19
EA200401303A1 (ru)	2005-04-28
AU2003216921B2 (en)	2008-03-13
UY27758A1 (es)	2003-11-28
ES2254917T3 (es)	2006-06-16
PL371561A1 (en)	2005-06-27
JP4559086B2 (ja)	2010-10-06
BR0309085A (pt)	2005-02-09
EP1621197A2 (fr)	2006-02-01
CA2481268A1 (fr)	2003-10-23
JP2005529105A (ja)	2005-09-29
NZ536284A (en)	2006-11-30
IL164391A0 (en)	2005-12-18
IL164391A (en)	2010-11-30
UA80125C2 (en)	2007-08-27
MXPA04009917A (es)	2004-12-07
NO20044097L (no)	2004-11-04
CA2481268C (fr)	2011-07-12
DE10216429A1 (de)	2003-10-23
HRP20040943B1 (hr)	2013-05-31
AR039275A1 (es)	2005-02-16

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ZA200302921B (en)	2004-04-19	Novel medicament compositions based on tiotropium salts and on salmeterol salts.
US20040002502A1 (en)	2004-01-01	Medicament combinations comprising heterocyclic compounds and a novel anticholinergic
CA2481268C (fr)	2011-07-12	Medicaments comprenant des steroides et un nouvel anticholinergique
EP1651224B1 (fr)	2011-10-05	Medicaments pour inhalation comportant un agent a activite anticholinergique et un betamimetique
CA2568834A1 (fr)	2006-01-12	Medicaments pour inhalation comprenant des steroides et un anticholinergique
AU2004262901B2 (en)	2010-05-13	Combination of an anticholinergic and a steroid and its use to treat respiratory disorders by inhalation
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