ZA200410046B - Molecular antigen arrays using a virus like particle derived from the AP205 coat protein. - Google Patents
Molecular antigen arrays using a virus like particle derived from the AP205 coat protein. Download PDFInfo
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- ZA200410046B ZA200410046B ZA200410046A ZA200410046A ZA200410046B ZA 200410046 B ZA200410046 B ZA 200410046B ZA 200410046 A ZA200410046 A ZA 200410046A ZA 200410046 A ZA200410046 A ZA 200410046A ZA 200410046 B ZA200410046 B ZA 200410046B
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- C12N2795/00—Bacteriophages
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- C12N2795/18011—Details ssRNA Bacteriophages positive-sense
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39612602P | 2002-07-17 | 2002-07-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200410046B true ZA200410046B (en) | 2006-03-29 |
Family
ID=30115977
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200410046A ZA200410046B (en) | 2002-07-17 | 2004-12-13 | Molecular antigen arrays using a virus like particle derived from the AP205 coat protein. |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US7138252B2 (de) |
| EP (2) | EP2351770A1 (de) |
| JP (3) | JP4726483B2 (de) |
| CN (2) | CN102061288A (de) |
| AT (1) | ATE542828T1 (de) |
| AU (1) | AU2003246690B2 (de) |
| BR (1) | BR0312935A (de) |
| CA (1) | CA2489410C (de) |
| IL (1) | IL165605A0 (de) |
| MX (1) | MXPA05000277A (de) |
| NZ (1) | NZ538083A (de) |
| RU (2) | RU2324704C2 (de) |
| WO (1) | WO2004007538A2 (de) |
| ZA (1) | ZA200410046B (de) |
Families Citing this family (93)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001085208A2 (en) * | 2000-05-05 | 2001-11-15 | Cytos Biotechnology Ag | Molecular antigen arrays and vaccines |
| US7320793B2 (en) * | 2001-01-19 | 2008-01-22 | Cytos Biotechnology Ag | Molecular antigen array |
| US7128911B2 (en) | 2001-01-19 | 2006-10-31 | Cytos Biotechnology Ag | Antigen arrays for treatment of bone disease |
| US7094409B2 (en) | 2001-01-19 | 2006-08-22 | Cytos Biotechnology Ag | Antigen arrays for treatment of allergic eosinophilic diseases |
| EP1450856B1 (de) | 2001-09-14 | 2009-11-11 | Cytos Biotechnology AG | VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG |
| US7115266B2 (en) | 2001-10-05 | 2006-10-03 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
| BR0311995A (pt) * | 2002-06-20 | 2005-04-05 | Cytos Biotechnology Ag | Partìculas semelhantes a vìrus empacotadas para o uso como adjuvantes: método de preparação e uso |
| JP4726483B2 (ja) * | 2002-07-17 | 2011-07-20 | サイトス バイオテクノロジー アーゲー | 分子抗原アレイ |
| KR101228376B1 (ko) * | 2002-07-18 | 2013-01-31 | 사이토스 바이오테크놀로지 아게 | 합텐-캐리어 컨쥬게이트 및 그의 용도 |
| DE60336902D1 (de) * | 2002-07-19 | 2011-06-09 | Cytos Biotechnology Ag | Impfstoffzusammensetzungen enthaltende amyloid beta 1-6 antigenarrays |
| US7537767B2 (en) | 2003-03-26 | 2009-05-26 | Cytis Biotechnology Ag | Melan-A- carrier conjugates |
| RU2351362C2 (ru) | 2003-03-26 | 2009-04-10 | Цитос Байотекнолоджи Аг | КОНЪЮГАТЫ ПЕПТИДА Melan-A, АНАЛОГА ВИРУСОПОДОБНОЙ ЧАСТИЦЫ |
| AU2005281743A1 (en) * | 2004-08-04 | 2006-03-16 | Cytos Biotechnology Ag | Carrier conjugates of GnRH-peptides |
| MX2007003171A (es) * | 2004-09-21 | 2007-05-23 | Cytos Biotechnology Ag | Particulas tipo virus que comprenden una proteina de fusion de la proteina de cubierta de ap205 y un polipeptido antigenico. |
| CN101052411B (zh) * | 2004-10-05 | 2011-04-06 | 赛托斯生物技术公司 | Vlp-抗原偶联物及其作为疫苗的用途 |
| AU2005298689A1 (en) | 2004-10-25 | 2006-05-04 | Cytos Biotechnology Ag | Gastric inhibitory polypeptide (GIP) antigen arrays and uses thereof |
| US20090123471A1 (en) * | 2004-10-29 | 2009-05-14 | Cytos Biotechnology Ag | T-Cadherin antigen arrays and uses thereof |
| GB0424563D0 (en) | 2004-11-05 | 2004-12-08 | Novartis Ag | Organic compounds |
| RU2007126553A (ru) * | 2004-12-13 | 2009-01-20 | Цитос Биотехнологи Аг (Ch) | Упорядоченные ряды антигенов ил-15 и их применение |
| PL1868642T3 (pl) * | 2005-03-18 | 2013-10-31 | Cytos Biotechnology Ag | Białka fuzyjne alergenów kocich i ich zastosowania |
| ATE515566T1 (de) | 2005-05-26 | 2011-07-15 | Cytos Biotechnology Ag | Skalierbares fermentationsverfahren |
| EP1746165A1 (de) | 2005-07-21 | 2007-01-24 | Cytos Biotechnology AG | Skalierbares Fermentations-Verfahren |
| RU2007147938A (ru) * | 2005-06-14 | 2009-07-20 | Цитос Биотехнологи Аг (Ch) | Конъюгаты антигенов и их применение |
| EP1736538A1 (de) * | 2005-06-21 | 2006-12-27 | Cytos Biotechnology AG | Prozess für die preparative Reinigung von Virus-ähnlichen Partikeln (VLPs) |
| ES2310062B1 (es) | 2005-07-15 | 2009-11-13 | Bionostra, S.L. | Particulas pseudovirales vacias quimericas derivadas del virus causante de la enfermedad de la bursitis infecciosa (ibdv), procedimiento de obtencion y aplicaciones. |
| US20110027220A1 (en) * | 2005-09-28 | 2011-02-03 | Cytos Biotechnology Ag | Interleukin-1 Conjugates and Uses Thereof |
| US20070166735A1 (en) * | 2005-12-08 | 2007-07-19 | South Dakota State University | Methods of in vitro propagation and detection of infectious prion |
| WO2007068747A1 (en) | 2005-12-14 | 2007-06-21 | Cytos Biotechnology Ag | Immunostimulatory nucleic acid packaged particles for the treatment of hypersensitivity |
| JP5437797B2 (ja) | 2006-06-12 | 2014-03-12 | サイトス バイオテクノロジー アーゲー | Rnaバクテリオファージのウイルス様粒子にオリゴヌクレオチドをパッケージ化するための方法 |
| US7534595B2 (en) * | 2006-06-12 | 2009-05-19 | Biomarin Pharmaceutical Inc. | Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof |
| CA2664418A1 (en) * | 2006-09-28 | 2008-04-03 | Cytos Biotechnology Ag | Interleukin-1 muteins linked to virus-like particles to treat il-1 associated diseases |
| US7998487B2 (en) * | 2007-02-16 | 2011-08-16 | The Salk Institute For Biological Studies | Antitoxin and vaccine platform based on nodavirus VLPs |
| JPWO2008133141A1 (ja) * | 2007-04-24 | 2010-07-22 | 東洋紡績株式会社 | オスモチン組換えタンパク質およびその製造方法、並びにその利用 |
| EA023303B1 (ru) | 2007-08-15 | 2016-05-31 | Сиркейшиа Лимитед | Пептидная композиция для формирования толерантности к клещам домашней пыли и ее применение |
| US8222206B2 (en) * | 2008-03-04 | 2012-07-17 | Taiwan Advance Bio-Pharm Inc. | Method of enhancing the mobilization of hematopoietic stem cells using TAT-HOXB4H |
| CA2721657A1 (en) * | 2008-04-22 | 2009-10-29 | Cytos Biotechnology Ag | Vaccine compositions for the treatment of dengue fever and uses thereof |
| MX337723B (es) | 2008-12-09 | 2016-03-15 | Pfizer Vaccines Llc | Vacuna de peptido ch3 de ige. |
| WO2010122164A1 (en) | 2009-04-23 | 2010-10-28 | Cytos Biotechnology Ag | VIRUS-LIKE PARTICLES OF BACTERIOPHAGE φCB5 |
| AU2010243490A1 (en) * | 2009-04-30 | 2011-11-24 | Cytos Biotechnology Ag | Influenza hemagglutinin compositions and uses thereof |
| CA2768346A1 (en) | 2009-07-30 | 2011-02-03 | Pfizer Vaccines Llc | Antigenic tau peptides and uses thereof |
| DK2473605T3 (en) | 2009-09-03 | 2018-05-28 | Pfizer Vaccines Llc | PCSK9-VACCINE |
| WO2011097266A1 (en) * | 2010-02-02 | 2011-08-11 | Amano Enzyme Usa, Ltd. | Use of proteases for gluten intolerance |
| EP2942061A3 (de) | 2010-06-07 | 2016-01-13 | Pfizer Vaccines LLC | Ige-ch3-peptidimpfstoff |
| WO2012131504A1 (en) | 2011-03-02 | 2012-10-04 | Pfizer Inc. | Pcsk9 vaccine |
| US20130028857A1 (en) | 2011-07-29 | 2013-01-31 | Selecta Biosciences, Inc. | Synthetic nanocarriers comprising polymers comprising multiple immunomodulatory agents |
| CN104011080B (zh) | 2011-12-22 | 2017-10-20 | 弗·哈夫曼-拉罗切有限公司 | 用于真核细胞的全长抗体展示系统及其用途 |
| JP6362543B2 (ja) | 2012-02-23 | 2018-07-25 | ジュノ セラピューティクス ゲーエムベーハー | 細胞および他の複雑な生物学的材料のクロマトグラフィーによる単離 |
| US12218609B2 (en) * | 2012-05-11 | 2025-02-04 | The Regents Of The University Of California | Virus-based piezoelectric energy generation |
| DE102013105144A1 (de) * | 2013-05-17 | 2014-11-20 | Arno Thaller | Pharmazeutisches Kombinationspräparat mit einem anti-idiotypischen Antikörperfragment |
| US10195257B2 (en) | 2013-07-28 | 2019-02-05 | Qantu Therapeutics, Inc. | Vaccine formulations comprising quillaja desacylsaponins and beta amyloid peptides or tau protein to induce a Th2 immune response |
| WO2015123291A1 (en) | 2014-02-11 | 2015-08-20 | The Usa, As Represented By The Secretary, Dept. Of Health And Human Services | Pcsk9 vaccine and methods of using the same |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| MA40824A (fr) | 2014-10-22 | 2017-08-29 | Saiba Gmbh | Particules de cmv de type virus modifié |
| US10526376B2 (en) | 2015-01-15 | 2020-01-07 | University Of Copenhagen | Virus-like particle with efficient epitope display |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| CA2995003A1 (en) * | 2015-09-08 | 2017-03-16 | Universitat Zurich | Compositions against cat allergy |
| EP3141600A1 (de) * | 2015-09-11 | 2017-03-15 | Institut National de la Recherche Agronomique | Nepovirus hüllprotein fusionspolypeptide und deren verwendungen |
| HK1258932A1 (zh) * | 2015-10-22 | 2019-11-22 | Juno Therapeutics Gmbh | 用於转导的方法、反应剂盒、反应剂和设备 |
| US11466253B2 (en) | 2015-10-22 | 2022-10-11 | Juno Therapeutics Gmbh | Methods for culturing cells and kits and apparatus for same |
| CN108474791B (zh) | 2015-10-22 | 2022-07-08 | 朱诺治疗学有限公司 | 培养细胞的方法及用于该方法的试剂盒和设备 |
| EP3368068B1 (de) | 2015-10-30 | 2020-11-18 | University of Copenhagen | Virusähnliche partikel mit effizienter epitopanzeige |
| KR20190056382A (ko) | 2016-09-02 | 2019-05-24 | 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 | 안정화된 그룹 2 인플루엔자 헤마글루티닌 줄기 영역 삼량체 및 그의 용도 |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| MA49288A (fr) | 2017-04-27 | 2020-03-04 | Juno Therapeutics Gmbh | Reactifs particulaires oligomères et leurs méthodes d'utilisation |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| EP3752194A4 (de) | 2018-02-13 | 2022-03-16 | Checkmate Pharmaceuticals, Inc. | Zusammensetzungen und verfahren für die tumorimmuntherapie |
| SG11202009647VA (en) | 2018-04-09 | 2020-10-29 | Checkmate Pharmaceuticals | Packaging oligonucleotides into virus-like particles |
| JP7366057B2 (ja) | 2018-04-19 | 2023-10-20 | チェックメイト ファーマシューティカルズ, インコーポレイテッド | 合成rig-i様受容体アゴニスト |
| SG11202101204TA (en) | 2018-08-09 | 2021-03-30 | Juno Therapeutics Inc | Processes for generating engineered cells and compositions thereof |
| EP3874024A1 (de) | 2018-10-31 | 2021-09-08 | Juno Therapeutics GmbH | Verfahren zur selektion und stimulation von zellen und vorrichtung dafür |
| US12433943B2 (en) * | 2019-02-08 | 2025-10-07 | University Of Washington | Nanoparticle-based influenza virus vaccines and uses thereof |
| JP2022529781A (ja) | 2019-04-17 | 2022-06-24 | コンパス パスファインダー リミテッド | サイロシビンによるうつ病及び他の様々な障害の治療 |
| US12161710B2 (en) | 2019-07-24 | 2024-12-10 | Unm Rainforest Innovations | Malaria immunogen and methods for using same |
| JP7707161B2 (ja) | 2019-10-23 | 2025-07-14 | チェックメイト ファーマシューティカルズ, インコーポレイテッド | 合成rig-i様受容体アゴニスト |
| US20230063876A1 (en) * | 2020-03-02 | 2023-03-02 | Unm Rainforest Innovations | Virus-Like Particle Vaccines for Opioid Drugs |
| WO2021215952A1 (ru) | 2020-04-24 | 2021-10-28 | Общество С Ограниченной Ответственностью "Индженик" | Способ получения частиц бактериофагов семейства levivirus |
| US12240813B2 (en) | 2020-05-19 | 2025-03-04 | Cybin Irl Limited | Deuterated tryptamine derivatives and methods of use |
| CN112285361B (zh) * | 2020-09-27 | 2023-12-05 | 中国人民解放军空军军医大学 | 排除抗-cd38单克隆抗体药物对抗人球蛋白检测干扰的试剂 |
| CN114634578B (zh) * | 2020-12-15 | 2024-04-02 | 榕森生物科技(北京)有限公司 | 针对新型冠状病毒感染的疫苗组合物 |
| CN114632148B (zh) * | 2020-12-15 | 2024-08-09 | 榕森生物科技(北京)有限公司 | 病原样抗原疫苗及其制备方法 |
| CN112480245B (zh) * | 2020-12-19 | 2023-08-18 | 上海佰君生物科技有限公司 | 一种疏水性环状肽配基纯化人免疫球蛋白g的应用 |
| US20240189407A1 (en) | 2021-04-12 | 2024-06-13 | Saiba AG | Modified virus-like particles of bacteriophage ap205 |
| WO2022229817A1 (en) | 2021-04-28 | 2022-11-03 | Bavarian Nordic A/S | Vaccines comprising virus-like particles displaying sars-cov-2 antigens and methods of use |
| WO2023288220A2 (en) * | 2021-07-12 | 2023-01-19 | Children's Hospital Medical Center | Differential cxcr4 expression on hematopoietic progenitor cells versus stem cells directs homing and long-term engraftment |
| US12121574B2 (en) | 2021-09-28 | 2024-10-22 | Unm Rainforest Innovations | Malaria immunogen and methods for using same |
| WO2024049946A1 (en) | 2022-08-31 | 2024-03-07 | Unm Rainforest Innovations | Compositions targeting apoptosis-associated speck-like protein with caspase activation and recruitment domain (asc) and methods of use |
| EP4593874A2 (de) | 2022-09-30 | 2025-08-06 | Bavarian Nordic A/S | Virusähnliche partikel mit sars-cov-2-antigenen als booster-impfstoffe und verwendungen davon |
| CN115819623A (zh) * | 2022-12-12 | 2023-03-21 | 长春百克生物科技股份公司 | 一种重组病毒样颗粒疫苗组合物的制备及应用 |
| EP4737572A1 (de) * | 2023-06-29 | 2026-05-06 | Shenzhen Herz Life Science Technology Co., Ltd | Herstellungsverfahren für kastrationsimpfstoff mit ap205 virus-ähnlicher partikeluntereinheit |
| CN116987700B (zh) * | 2023-07-13 | 2024-02-20 | 杭州赛基生物科技有限公司 | 一种人白细胞介素-5重组蛋白及其制备方法 |
| WO2025194374A1 (zh) * | 2024-03-20 | 2025-09-25 | 深圳赫兹生命科学技术有限公司 | 猫过敏原多肽片段及应用 |
Family Cites Families (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US394A (en) * | 1837-09-21 | Mode of regulating the temperature of inkiwg-rollers and ink used | ||
| US5334A (en) * | 1847-10-16 | Improvement in cutter-heads for plan ing-machines | ||
| US4722840A (en) | 1984-09-12 | 1988-02-02 | Chiron Corporation | Hybrid particle immunogens |
| US5374426A (en) | 1986-09-03 | 1994-12-20 | University Of Saskatchewan | Rotavirus nucleocapsid protein VP6 in vaccine compositions |
| CA1319101C (en) | 1986-09-03 | 1993-06-15 | Marta Iris Sabara | Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules |
| WO1988001873A1 (en) | 1986-09-22 | 1988-03-24 | Emory University | Vaccine and method of preparation |
| US5143726A (en) | 1986-12-09 | 1992-09-01 | The Scripps Research Institute | T cell epitopes of the hepatitis B virus nucleocapsid protein |
| US4918166A (en) | 1987-04-10 | 1990-04-17 | Oxford Gene Systems Limited | Particulate hybrid HIV antigens |
| GB8903313D0 (en) | 1989-02-14 | 1989-04-05 | Wellcome Found | Conjugates |
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| ATE121754T1 (de) | 1989-09-04 | 1995-05-15 | Wellcome Found | Vakzine gegen bordetella. |
| ES2284161T3 (es) | 1990-01-12 | 2007-11-01 | Amgen Fremont Inc. | Generacion de anticuerpos xenogenicos. |
| US5178882A (en) | 1990-06-22 | 1993-01-12 | The Regents Of The University Of California | Viral decoy vaccine |
| US5334394A (en) | 1990-06-22 | 1994-08-02 | The Regents Of The University Of California | Human immunodeficiency virus decoy |
| SE9003978D0 (sv) | 1990-12-13 | 1990-12-13 | Henrik Garoff | Dna expressionssystem baserade paa ett virus replikon |
| WO1992011291A1 (en) | 1990-12-20 | 1992-07-09 | Smithkline Beecham Biologicals (S.A.) | Vaccines based on hepatitis b surface antigen |
| GB9114003D0 (en) | 1991-06-28 | 1991-08-14 | Mastico Robert A | Chimaeric protein |
| US6004763A (en) | 1992-09-11 | 1999-12-21 | Institut Pasteur | Antigen-carrying microparticles and their use in the induction of humoral or cellular responses |
| FR2695563B1 (fr) | 1992-09-11 | 1994-12-02 | Pasteur Institut | Microparticules portant des antigènes et leur utilisation pour l'induction de réponses humorales ou cellulaires. |
| JPH08505625A (ja) | 1993-01-11 | 1996-06-18 | ダナ−ファーバー キャンサー インスティチュート | 細胞毒性tリンパ球応答の誘導 |
| AU6172194A (en) | 1993-02-08 | 1994-08-29 | Paravax, Inc. | Defective sindbis virus vectors that express (toxoplasma gondii) p30 antigens |
| US6015686A (en) | 1993-09-15 | 2000-01-18 | Chiron Viagene, Inc. | Eukaryotic layered vector initiation systems |
| AT402898B (de) | 1994-08-08 | 1997-09-25 | Int Centre Genetic Eng & Bio | Molekulares präsentiersystem |
| WO1996030523A2 (en) | 1995-03-31 | 1996-10-03 | Hans Wolf | Antigen presentation system based on retrovirus-like particles |
| US5792462A (en) | 1995-05-23 | 1998-08-11 | University Of North Carolina At Chapel Hill | Alphavirus RNA replicon systems |
| CA2245497C (en) | 1996-03-01 | 2009-02-24 | Novartis Ag | Peptide immunogens for vaccination against and treatment of allergy |
| US5770380A (en) | 1996-09-13 | 1998-06-23 | University Of Pittsburgh | Synthetic antibody mimics--multiple peptide loops attached to a molecular scaffold |
| GB9621091D0 (en) | 1996-10-09 | 1996-11-27 | Fondation Pour Le Perfectionem | Attenuated microorganisms strains and their uses |
| WO1999007839A2 (en) | 1997-08-05 | 1999-02-18 | Vlaams Interuniversitair Instituut Voor Biotechnologie | Immunoprotective influenza antigen and its use in vaccination |
| US6169175B1 (en) | 1997-08-06 | 2001-01-02 | Centers For Disease Control And Prevention | Preparation and use of recombinant influenza A virus M2 construct vaccines |
| US6054312A (en) | 1997-08-29 | 2000-04-25 | Selective Genetics, Inc. | Receptor-mediated gene delivery using bacteriophage vectors |
| ATE249240T1 (de) | 1998-02-12 | 2003-09-15 | Immune Complex Corp | Strategisch modifizierte hepatitis b kernproteine und ihre derivate |
| US5990085A (en) | 1998-05-04 | 1999-11-23 | Michigan State University | Inhibin-HBc fusion protein |
| TWI227241B (en) | 1998-06-20 | 2005-02-01 | United Biomedical Inc | IgE-CH3 domain antigen peptide, peptide conjugate containing the same, and pharmaceutical composition for treating allergies containing the peptide conjugate |
| ATE314095T1 (de) | 1998-10-21 | 2006-01-15 | Us Health | Virusähnliche partikel zur induktion von autoantikörpern |
| US6380364B1 (en) | 1998-11-23 | 2002-04-30 | Loyola University Of Chicago | Chimeric biotin-binding papillomavirus protein |
| PL192016B1 (pl) | 1998-11-30 | 2006-08-31 | Cytos Biotechnology Ag | Kompozycja, sposób wytwarzania sztucznego, uporządkowanego i powtarzalnego układu antygenu, zastosowanie kompozycji oraz kompozycja szczepionki |
| KR100715954B1 (ko) | 1998-12-04 | 2007-05-09 | 바이오겐 아이덱 엠에이 인코포레이티드 | 펩티드 리간드에 의하여 부착된 다중 면역원성 성분을보유한 hbv 코어 항원 입자 |
| WO2000050461A1 (en) | 1999-02-25 | 2000-08-31 | Smithkline Beecham Biologicals S.A. | Epitopes or mimotopes derived from the c-epsilon-3 or c-epsilon-4 domains of ige, antagonists thereof, and their therapeutic uses |
| CA2365970A1 (en) | 1999-04-07 | 2000-10-12 | Thomas Jefferson University | Chemokine-derived synthetic peptides |
| US20030086938A1 (en) | 2000-02-21 | 2003-05-08 | Jensen Martin Roland | Novel methods for down-regulation of amyloid |
| WO2001085208A2 (en) | 2000-05-05 | 2001-11-15 | Cytos Biotechnology Ag | Molecular antigen arrays and vaccines |
| US7128911B2 (en) * | 2001-01-19 | 2006-10-31 | Cytos Biotechnology Ag | Antigen arrays for treatment of bone disease |
| US7320793B2 (en) | 2001-01-19 | 2008-01-22 | Cytos Biotechnology Ag | Molecular antigen array |
| US7094409B2 (en) | 2001-01-19 | 2006-08-22 | Cytos Biotechnology Ag | Antigen arrays for treatment of allergic eosinophilic diseases |
| EP1450856B1 (de) | 2001-09-14 | 2009-11-11 | Cytos Biotechnology AG | VERPACKUNG VON IMMUNSTIMULIERENDEM CpG IN VIRUSÄHNLICHEN PARTIKELN: HERSTELLUNGSVERFAHREN UND VERWENDUNG |
| US8197843B2 (en) | 2001-09-21 | 2012-06-12 | Coloplast A/S | Device for the administration of an active agent to the human skin |
| US7115266B2 (en) * | 2001-10-05 | 2006-10-03 | Cytos Biotechnology Ag | Angiotensin peptide-carrier conjugates and uses thereof |
| BR0213941A (pt) * | 2001-11-07 | 2004-08-31 | Cytos Biotechnology Ag | Arranjos de antìgeno para o tratamento de doença óssea |
| JP3787697B2 (ja) | 2002-01-08 | 2006-06-21 | 独立行政法人理化学研究所 | 重イオンビーム照射によるキメラ植物の作出方法 |
| JP4726483B2 (ja) * | 2002-07-17 | 2011-07-20 | サイトス バイオテクノロジー アーゲー | 分子抗原アレイ |
| KR101228376B1 (ko) * | 2002-07-18 | 2013-01-31 | 사이토스 바이오테크놀로지 아게 | 합텐-캐리어 컨쥬게이트 및 그의 용도 |
| DE60336902D1 (de) * | 2002-07-19 | 2011-06-09 | Cytos Biotechnology Ag | Impfstoffzusammensetzungen enthaltende amyloid beta 1-6 antigenarrays |
| US7537767B2 (en) * | 2003-03-26 | 2009-05-26 | Cytis Biotechnology Ag | Melan-A- carrier conjugates |
| RU2351362C2 (ru) * | 2003-03-26 | 2009-04-10 | Цитос Байотекнолоджи Аг | КОНЪЮГАТЫ ПЕПТИДА Melan-A, АНАЛОГА ВИРУСОПОДОБНОЙ ЧАСТИЦЫ |
| CA2533660C (en) | 2003-07-25 | 2013-04-23 | Agroplast Aps | Method and system for treating waste matter from animals containing urea |
| AU2005298689A1 (en) * | 2004-10-25 | 2006-05-04 | Cytos Biotechnology Ag | Gastric inhibitory polypeptide (GIP) antigen arrays and uses thereof |
| PL1868642T3 (pl) * | 2005-03-18 | 2013-10-31 | Cytos Biotechnology Ag | Białka fuzyjne alergenów kocich i ich zastosowania |
-
2003
- 2003-07-14 JP JP2004520607A patent/JP4726483B2/ja not_active Expired - Fee Related
- 2003-07-14 MX MXPA05000277A patent/MXPA05000277A/es active IP Right Grant
- 2003-07-14 CN CN2010101587965A patent/CN102061288A/zh active Pending
- 2003-07-14 AU AU2003246690A patent/AU2003246690B2/en not_active Ceased
- 2003-07-14 NZ NZ538083A patent/NZ538083A/en not_active IP Right Cessation
- 2003-07-14 CA CA2489410A patent/CA2489410C/en not_active Expired - Fee Related
- 2003-07-14 BR BR0312935-7A patent/BR0312935A/pt not_active IP Right Cessation
- 2003-07-14 CN CN038168626A patent/CN1668637B/zh not_active Expired - Fee Related
- 2003-07-14 US US10/617,876 patent/US7138252B2/en not_active Expired - Fee Related
- 2003-07-14 EP EP10011277A patent/EP2351770A1/de not_active Withdrawn
- 2003-07-14 AT AT03763829T patent/ATE542828T1/de active
- 2003-07-14 EP EP03763829A patent/EP1532167B1/de not_active Expired - Lifetime
- 2003-07-14 WO PCT/EP2003/007572 patent/WO2004007538A2/en not_active Ceased
- 2003-07-14 RU RU2005104235/13A patent/RU2324704C2/ru not_active IP Right Cessation
-
2004
- 2004-12-07 IL IL16560504A patent/IL165605A0/xx unknown
- 2004-12-13 ZA ZA200410046A patent/ZA200410046B/en unknown
-
2006
- 2006-11-20 US US11/601,687 patent/US7494656B2/en not_active Expired - Fee Related
-
2007
- 2007-12-03 RU RU2007144895/13A patent/RU2007144895A/ru not_active Application Discontinuation
-
2008
- 2008-12-22 US US12/341,763 patent/US20100092508A1/en not_active Abandoned
-
2009
- 2009-11-25 JP JP2009267660A patent/JP2010075196A/ja active Pending
-
2010
- 2010-11-05 JP JP2010248015A patent/JP2011087580A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN102061288A (zh) | 2011-05-18 |
| MXPA05000277A (es) | 2005-03-31 |
| CN1668637A (zh) | 2005-09-14 |
| HK1078880A1 (en) | 2006-03-24 |
| US7494656B2 (en) | 2009-02-24 |
| US7138252B2 (en) | 2006-11-21 |
| JP2011087580A (ja) | 2011-05-06 |
| BR0312935A (pt) | 2005-06-21 |
| IL165605A0 (en) | 2006-01-15 |
| WO2004007538A3 (en) | 2004-03-04 |
| US20100092508A1 (en) | 2010-04-15 |
| NZ538083A (en) | 2006-08-31 |
| US20040076611A1 (en) | 2004-04-22 |
| US20070128219A1 (en) | 2007-06-07 |
| RU2007144895A (ru) | 2009-06-10 |
| ATE542828T1 (de) | 2012-02-15 |
| JP2010075196A (ja) | 2010-04-08 |
| CA2489410C (en) | 2015-01-13 |
| EP1532167A2 (de) | 2005-05-25 |
| RU2324704C2 (ru) | 2008-05-20 |
| WO2004007538A2 (en) | 2004-01-22 |
| JP4726483B2 (ja) | 2011-07-20 |
| EP1532167B1 (de) | 2012-01-25 |
| CA2489410A1 (en) | 2004-01-22 |
| EP2351770A1 (de) | 2011-08-03 |
| AU2003246690B2 (en) | 2010-03-11 |
| RU2005104235A (ru) | 2005-09-10 |
| CN1668637B (zh) | 2010-05-26 |
| JP2006510347A (ja) | 2006-03-30 |
| AU2003246690A1 (en) | 2004-02-02 |
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