ZA200707933B - Substituted aryl 1.4-pyrazine derivatives - Google Patents

Substituted aryl 1.4-pyrazine derivatives

Info

Publication number
ZA200707933B
ZA200707933B ZA200707933A ZA200707933A ZA200707933B ZA 200707933 B ZA200707933 B ZA 200707933B ZA 200707933 A ZA200707933 A ZA 200707933A ZA 200707933 A ZA200707933 A ZA 200707933A ZA 200707933 B ZA200707933 B ZA 200707933B
Authority
ZA
South Africa
Prior art keywords
substituted aryl
pyrazine derivatives
pyrazine
derivatives
aryl
Prior art date
Application number
ZA200707933A
Other languages
English (en)
Inventor
Verhoest Patrick Robert
Hoffman Robert Louis
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ZA200707933B publication Critical patent/ZA200707933B/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4965—Non-condensed pyrazines
    • A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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  • Veterinary Medicine (AREA)
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  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
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  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
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  • Pulmonology (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Hematology (AREA)
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  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
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ZA200707933A 2005-03-17 2007-09-17 Substituted aryl 1.4-pyrazine derivatives ZA200707933B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US66291705P 2005-03-17 2005-03-17

Publications (1)

Publication Number Publication Date
ZA200707933B true ZA200707933B (en) 2009-08-26

Family

ID=36617394

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200707933A ZA200707933B (en) 2005-03-17 2007-09-17 Substituted aryl 1.4-pyrazine derivatives

Country Status (26)

Country Link
US (1) US20060211710A1 (fr)
EP (1) EP1871763A1 (fr)
JP (1) JP2008533124A (fr)
KR (1) KR20070113294A (fr)
CN (1) CN101160304A (fr)
AP (1) AP2007004174A0 (fr)
AR (1) AR056279A1 (fr)
AU (1) AU2006238976A1 (fr)
BR (1) BRPI0606284A2 (fr)
CA (1) CA2601600C (fr)
CR (1) CR9436A (fr)
DO (1) DOP2006000056A (fr)
EA (1) EA012874B1 (fr)
GT (1) GT200600116A (fr)
IL (1) IL185997A0 (fr)
MA (1) MA29336B1 (fr)
MX (1) MX2007011423A (fr)
NL (1) NL1031384C2 (fr)
NO (1) NO20075209L (fr)
PE (1) PE20061108A1 (fr)
TN (1) TNSN07355A1 (fr)
TW (1) TWI315670B (fr)
UA (1) UA86873C2 (fr)
UY (1) UY29418A1 (fr)
WO (1) WO2006114666A1 (fr)
ZA (1) ZA200707933B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0525068D0 (en) 2005-12-08 2006-01-18 Novartis Ag Organic compounds
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
JP5770197B2 (ja) * 2009-10-30 2015-08-26 ヤンセン ファーマシューティカ エヌ．ベー． デルタオピオイド受容体調節因子としてのピラジン
JP2013518085A (ja) 2010-02-01 2013-05-20 ノバルティス アーゲー ＣＲＦ−１受容体アンタゴニストとしてのピラゾロ［５，１ｂ］オキサゾール誘導体
AR080056A1 (es) 2010-02-01 2012-03-07 Novartis Ag Derivados de ciclohexil-amida como antagonistas de los receptores de crf
JP5748777B2 (ja) 2010-02-02 2015-07-15 ノバルティス アーゲー Ｃｒｆ受容体アンタゴニストとしてのシクロヘキシルアミド誘導体
JP2022062287A (ja) * 2019-02-27 2022-04-20 住友化学株式会社 ピリジルピラジン化合物の製造方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5872136A (en) * 1996-04-03 1999-02-16 Merck & Co., Inc. Arylheteroaryl inhibitors of farnesyl-protein transferase
US5883105A (en) * 1996-04-03 1999-03-16 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5880140A (en) * 1996-04-03 1999-03-09 Merck & Co., Inc. Biheteroaryl inhibitors of farnesyl-protein transferase
PA8467401A1 (es) * 1998-02-17 2000-09-29 Pfizer Prod Inc Procedimiento para tratar la insuficiencia cardiaca
MXPA02003436A (es) * 1999-10-07 2002-08-20 Amgen Inc Inhibidores de triazina cinasa.
CO5271670A1 (es) * 1999-10-29 2003-04-30 Pfizer Prod Inc Antagonistas del factor de liberacion de corticitropina y composiciones relacionadas
PL365238A1 (en) * 2000-02-16 2004-12-27 Neurogen Corporation Substituted arylpyrazines
BR0214309A (pt) * 2001-11-21 2004-10-13 Upjohn Co Derivados aril-1,4-pirazina substituìdos
US6992087B2 (en) * 2001-11-21 2006-01-31 Pfizer Inc Substituted aryl 1,4-pyrazine derivatives
JP2005533014A (ja) * 2002-04-26 2005-11-04 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 置換ピラジン誘導体
US20040116444A1 (en) * 2002-09-12 2004-06-17 Corbett Jeffrey W. Substituted 1,4-pyrazine derivatives

Also Published As

Publication number Publication date
MX2007011423A (es) 2007-10-12
WO2006114666A1 (fr) 2006-11-02
CA2601600A1 (fr) 2006-11-02
GT200600116A (es) 2006-11-09
EA200701758A1 (ru) 2008-02-28
CR9436A (es) 2007-11-23
TW200700067A (en) 2007-01-01
NL1031384A1 (nl) 2006-09-20
AR056279A1 (es) 2007-10-03
PE20061108A1 (es) 2006-10-13
AU2006238976A1 (en) 2006-11-02
NO20075209L (no) 2007-10-11
TNSN07355A1 (fr) 2008-12-31
WO2006114666A8 (fr) 2008-04-03
KR20070113294A (ko) 2007-11-28
BRPI0606284A2 (pt) 2009-06-09
CA2601600C (fr) 2010-09-14
MA29336B1 (fr) 2008-03-03
EA012874B1 (ru) 2009-12-30
EP1871763A1 (fr) 2008-01-02
DOP2006000056A (es) 2006-08-30
UY29418A1 (es) 2006-10-31
US20060211710A1 (en) 2006-09-21
IL185997A0 (en) 2008-01-20
UA86873C2 (en) 2009-05-25
AP2007004174A0 (en) 2007-10-31
NL1031384C2 (nl) 2007-01-23
CN101160304A (zh) 2008-04-09
TWI315670B (en) 2009-10-11
JP2008533124A (ja) 2008-08-21

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