ZA200802995B - Pyrazolopyrimidines as protein kinase inhibitors - Google Patents
Pyrazolopyrimidines as protein kinase inhibitorsInfo
- Publication number
- ZA200802995B ZA200802995B ZA200802995A ZA200802995A ZA200802995B ZA 200802995 B ZA200802995 B ZA 200802995B ZA 200802995 A ZA200802995 A ZA 200802995A ZA 200802995 A ZA200802995 A ZA 200802995A ZA 200802995 B ZA200802995 B ZA 200802995B
- Authority
- ZA
- South Africa
- Prior art keywords
- pyrazolopyrimidines
- protein kinase
- kinase inhibitors
- inhibitors
- protein
- Prior art date
Links
- APXRHPDHORGIEB-UHFFFAOYSA-N 1H-pyrazolo[4,3-d]pyrimidine Chemical class N1=CN=C2C=NNC2=C1 APXRHPDHORGIEB-UHFFFAOYSA-N 0.000 title 1
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 title 1
- 239000003909 protein kinase inhibitor Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72419705P | 2005-10-06 | 2005-10-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200802995B true ZA200802995B (en) | 2009-02-25 |
Family
ID=37560916
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200802995A ZA200802995B (en) | 2005-10-06 | 2008-04-04 | Pyrazolopyrimidines as protein kinase inhibitors |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7776865B2 (es) |
| EP (1) | EP1931676B1 (es) |
| JP (2) | JP5052518B2 (es) |
| KR (1) | KR20080063806A (es) |
| CN (1) | CN101321760A (es) |
| AR (1) | AR056206A1 (es) |
| AT (1) | ATE533770T1 (es) |
| AU (1) | AU2006299338A1 (es) |
| BR (1) | BRPI0617150A2 (es) |
| CA (1) | CA2624882C (es) |
| EC (1) | ECSP088350A (es) |
| IL (1) | IL190598A0 (es) |
| NO (1) | NO20082092L (es) |
| PE (1) | PE20070543A1 (es) |
| RU (1) | RU2008117298A (es) |
| TW (1) | TW200745123A (es) |
| WO (1) | WO2007041712A1 (es) |
| ZA (1) | ZA200802995B (es) |
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| KR20090019796A (ko) * | 2006-05-22 | 2009-02-25 | 쉐링 코포레이션 | ＣＤＫ 억제제로서의 피라졸로[1,5-ａ]피리미딘 |
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| CN102088853A (zh) * | 2008-05-12 | 2011-06-08 | 安内斯蒂克斯公司 | 改善学习和记忆的化合物 |
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| PA8851101A1 (es) * | 2008-12-16 | 2010-07-27 | Lilly Co Eli | Compuesto amino pirazol |
| KR20110114663A (ko) * | 2009-02-13 | 2011-10-19 | 바이엘 파마 악티엔게젤샤프트 | 융합된 피리미딘 |
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| EP2473041B1 (en) | 2009-09-04 | 2018-03-07 | Merck Sharp & Dohme Corp. | Modulators of cell cycle checkpoints and their use in combination with checkpoint kinase inhibitors |
| JP5607174B2 (ja) * | 2009-12-01 | 2014-10-15 | アッヴィ・インコーポレイテッド | 新規な三環式化合物 |
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| AR049769A1 (es) * | 2004-01-22 | 2006-09-06 | Novartis Ag | Derivados de pirazolo(1,5-a)pirimidin 7-il-amina para utilizarse en el tratamiento de enfermedades dependientes de la quinasa de proteina |
| ATE448229T1 (de) * | 2005-01-19 | 2009-11-15 | Merck & Co Inc | Bicyclische pyrimidine als dipeptidylpeptidase-iv-hemmer zur behandlung bzw. prävention von diabetes |
| GB0515026D0 (en) * | 2005-07-21 | 2005-08-31 | Novartis Ag | Organic compounds |
| CA2624882C (en) * | 2005-10-06 | 2014-05-20 | Schering Corporation | Pyrazolopyrimidines as protein kinase inhibitors |
-
2006
- 2006-10-04 CA CA2624882A patent/CA2624882C/en not_active Expired - Fee Related
- 2006-10-04 AR ARP060104364A patent/AR056206A1/es not_active Application Discontinuation
- 2006-10-04 BR BRPI0617150-8A patent/BRPI0617150A2/pt not_active IP Right Cessation
- 2006-10-04 TW TW095136815A patent/TW200745123A/zh unknown
- 2006-10-04 AU AU2006299338A patent/AU2006299338A1/en not_active Abandoned
- 2006-10-04 US US11/542,921 patent/US7776865B2/en active Active
- 2006-10-04 CN CNA2006800455049A patent/CN101321760A/zh active Pending
- 2006-10-04 WO PCT/US2006/039136 patent/WO2007041712A1/en not_active Ceased
- 2006-10-04 EP EP06816408A patent/EP1931676B1/en active Active
- 2006-10-04 JP JP2008534711A patent/JP5052518B2/ja not_active Expired - Fee Related
- 2006-10-04 KR KR1020087010465A patent/KR20080063806A/ko not_active Withdrawn
- 2006-10-04 PE PE2006001206A patent/PE20070543A1/es not_active Application Discontinuation
- 2006-10-04 RU RU2008117298/04A patent/RU2008117298A/ru not_active Application Discontinuation
- 2006-10-04 AT AT06816408T patent/ATE533770T1/de active
-
2008
- 2008-04-03 IL IL190598A patent/IL190598A0/en unknown
- 2008-04-04 ZA ZA200802995A patent/ZA200802995B/xx unknown
- 2008-04-04 EC EC2008008350A patent/ECSP088350A/es unknown
- 2008-05-05 NO NO20082092A patent/NO20082092L/no not_active Application Discontinuation
-
2012
- 2012-01-27 JP JP2012015794A patent/JP2012082233A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AR056206A1 (es) | 2007-09-26 |
| PE20070543A1 (es) | 2007-06-14 |
| EP1931676A1 (en) | 2008-06-18 |
| CA2624882A1 (en) | 2007-04-12 |
| WO2007041712A1 (en) | 2007-04-12 |
| ECSP088350A (es) | 2008-05-30 |
| US7776865B2 (en) | 2010-08-17 |
| RU2008117298A (ru) | 2009-11-20 |
| JP5052518B2 (ja) | 2012-10-17 |
| US20070083044A1 (en) | 2007-04-12 |
| ATE533770T1 (de) | 2011-12-15 |
| BRPI0617150A2 (pt) | 2011-07-12 |
| CA2624882C (en) | 2014-05-20 |
| TW200745123A (en) | 2007-12-16 |
| KR20080063806A (ko) | 2008-07-07 |
| CN101321760A (zh) | 2008-12-10 |
| JP2012082233A (ja) | 2012-04-26 |
| IL190598A0 (en) | 2008-11-03 |
| JP2009511491A (ja) | 2009-03-19 |
| NO20082092L (no) | 2008-07-04 |
| AU2006299338A1 (en) | 2007-04-12 |
| EP1931676B1 (en) | 2011-11-16 |
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