ZA200903125B - Self-assembling nanoparticles composed of transmembrane peptides and their application for specific intra-tumor delivery of anti-cancer drugs - Google Patents

Self-assembling nanoparticles composed of transmembrane peptides and their application for specific intra-tumor delivery of anti-cancer drugs

Info

Publication number
ZA200903125B
ZA200903125B ZA200903125A ZA200903125A ZA200903125B ZA 200903125 B ZA200903125 B ZA 200903125B ZA 200903125 A ZA200903125 A ZA 200903125A ZA 200903125 A ZA200903125 A ZA 200903125A ZA 200903125 B ZA200903125 B ZA 200903125B
Authority
ZA
South Africa
Prior art keywords
self
application
cancer drugs
nanoparticles composed
specific intra
Prior art date
Application number
ZA200903125A
Other languages
English (en)
Inventor
Nadya I Tarasova
Sergey G Tarasov
Christopher J Michejda
Original Assignee
Us Gov Health & Human Serv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv filed Critical Us Gov Health & Human Serv
Publication of ZA200903125B publication Critical patent/ZA200903125B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA200903125A 2006-11-07 2009-05-06 Self-assembling nanoparticles composed of transmembrane peptides and their application for specific intra-tumor delivery of anti-cancer drugs ZA200903125B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86466506P 2006-11-07 2006-11-07

Publications (1)

Publication Number Publication Date
ZA200903125B true ZA200903125B (en) 2010-05-26

Family

ID=39365311

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200903125A ZA200903125B (en) 2006-11-07 2009-05-06 Self-assembling nanoparticles composed of transmembrane peptides and their application for specific intra-tumor delivery of anti-cancer drugs

Country Status (9)

Country Link
US (1) US9326950B2 (2)
EP (1) EP2086521A2 (2)
JP (1) JP2010509241A (2)
CN (1) CN101610759A (2)
AU (1) AU2007316416A1 (2)
CA (1) CA2668638A1 (2)
NZ (1) NZ576769A (2)
WO (1) WO2008058125A2 (2)
ZA (1) ZA200903125B (2)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2086521A2 (en) * 2006-11-07 2009-08-12 Government of the United States of America, Represented by the Secretary, Department of Health and Human Services Self-assembling nanoparticles composed of transmembrane peptides and their application for specific intra-tumor delivery of anti-cancer drugs
WO2012162628A2 (en) 2011-05-25 2012-11-29 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Lipopeptide inhibitors of ras oncoproteins
EP2911701A4 (en) 2012-10-23 2016-06-08 Univ Johns Hopkins Novel self-assembling drug amphiphiles and methods for synthesis and application
ES2625024B1 (es) * 2015-12-18 2018-05-10 Consejo Superior De Investigaciones Cientificas Material que comprende tectómeros de oligoglicina y nanohilos
US11246924B2 (en) 2016-04-01 2022-02-15 Duke University Alpha-helical peptide nanofibers as a self-adjuvanting vaccine platform
WO2019018572A1 (en) * 2017-07-18 2019-01-24 Duke University COMPOSITIONS AND METHODS COMPRISING SELF-ASSEMBLY PEPTIDE-POLYMER NANOFIBERS FOR SUBLINGUAL IMMUNIZATION
WO2026018050A1 (en) 2024-07-14 2026-01-22 Zare Zardini Hadi Pistacia-derived bioactive peptides encapsulated in soy protein nanoparticles as an anticancer drug

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE211471T1 (de) 1996-04-12 2002-01-15 Us Gov Health & Human Serv Acridonderivate als antineoplastische-und antiretrovirale mittel
US7105488B1 (en) 1998-02-27 2006-09-12 The United States Of America As Represented By The Department Of Health And Human Services G protein-coupled receptor antagonists
AU760208B2 (en) 1998-02-27 2003-05-08 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The G protein-coupled receptor antagonists
WO2001036477A2 (en) * 1999-11-18 2001-05-25 The Government Of The United States, As Represented By The Secretary Of The Department Of Health And Human Services Inhibition of abc transporters by transmembrane domain analogs
AU2001240054B2 (en) 2000-03-07 2005-08-11 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services 1,8-Naphthalimide Imidazo[4,5,1-de]acridones with Anti-Tumor Activity
AU2001275423B2 (en) 2000-06-09 2007-01-11 Regulon, Inc. Encapsulation of polynucleotides and drugs into targeted liposomes
AU2002240201A1 (en) * 2001-02-02 2002-08-19 Yale University Peptides for facilitating composite receptor expression and translocation of macromolecules
US20070009441A1 (en) * 2004-07-08 2007-01-11 Molecular Therapeutics, Inc. Biodegradable nanoparticles
EP2086521A2 (en) * 2006-11-07 2009-08-12 Government of the United States of America, Represented by the Secretary, Department of Health and Human Services Self-assembling nanoparticles composed of transmembrane peptides and their application for specific intra-tumor delivery of anti-cancer drugs

Also Published As

Publication number Publication date
US9326950B2 (en) 2016-05-03
EP2086521A2 (en) 2009-08-12
CN101610759A (zh) 2009-12-23
US20100034896A1 (en) 2010-02-11
WO2008058125A2 (en) 2008-05-15
NZ576769A (en) 2012-01-12
WO2008058125A3 (en) 2008-10-16
AU2007316416A1 (en) 2008-05-15
CA2668638A1 (en) 2008-05-15
JP2010509241A (ja) 2010-03-25

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