ZA747820B - Isoquinoline derivatives and processes for their preparation - Google Patents
Isoquinoline derivatives and processes for their preparationInfo
- Publication number
- ZA747820B ZA747820B ZA00747820A ZA747820A ZA747820B ZA 747820 B ZA747820 B ZA 747820B ZA 00747820 A ZA00747820 A ZA 00747820A ZA 747820 A ZA747820 A ZA 747820A ZA 747820 B ZA747820 B ZA 747820B
- Authority
- ZA
- South Africa
- Prior art keywords
- processes
- preparation
- isoquinoline derivatives
- isoquinoline
- derivatives
- Prior art date
Links
- 125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2361390A DE2361390A1 (de) | 1973-12-10 | 1973-12-10 | Isochinolinderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA747820B true ZA747820B (en) | 1975-12-31 |
Family
ID=5900348
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00747820A ZA747820B (en) | 1973-12-10 | 1974-12-09 | Isoquinoline derivatives and processes for their preparation |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US3985881A (cs) |
| JP (1) | JPS5088077A (cs) |
| AT (1) | AT351026B (cs) |
| BE (1) | BE823027A (cs) |
| CA (1) | CA1053675A (cs) |
| CH (1) | CH605776A5 (cs) |
| CS (1) | CS188933B2 (cs) |
| DD (1) | DD115666A5 (cs) |
| DE (1) | DE2361390A1 (cs) |
| DK (1) | DK137007C (cs) |
| ES (1) | ES432716A1 (cs) |
| FR (1) | FR2253522B1 (cs) |
| GB (1) | GB1447611A (cs) |
| HU (1) | HU171483B (cs) |
| IL (1) | IL46160A0 (cs) |
| NL (1) | NL7416050A (cs) |
| SE (1) | SE7415247L (cs) |
| ZA (1) | ZA747820B (cs) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2504250A1 (de) * | 1975-02-01 | 1976-08-05 | Merck Patent Gmbh | Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung |
| US4232160A (en) * | 1978-10-18 | 1980-11-04 | Miles Laboratories, Inc. | Isoquinoline propionamides exhibiting analgesic properties |
| US4556712A (en) * | 1981-05-20 | 1985-12-03 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Preparation and racemization of chiral 1-benzyl-1,2,3,4-tetrahydroisoquinolines |
| GB8601796D0 (en) * | 1986-01-24 | 1986-02-26 | Zambeletti Spa L | Compounds |
| DE3713743A1 (de) * | 1987-04-24 | 1988-11-17 | Boehringer Ingelheim Kg | Kondensierte bis-(3,4-dihydro-l-pyridinyl)methane, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE68910999T2 (de) * | 1988-02-19 | 1994-03-24 | Smithkline Beecham Farma | 1,2,3,4-Tetrahydroisoquinoline, Verfharen zu ihrer Herstellung und ihre Verwendung als Kappa-Rezeptor Agonisten. |
| KR890012970A (ko) * | 1988-02-23 | 1989-09-20 | 추후보충 | 테트라히드로 이소퀴놀린 유도체 |
| DE3827727A1 (de) * | 1988-08-16 | 1990-02-22 | Boehringer Ingelheim Kg | Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion |
| GB8827479D0 (en) * | 1988-11-24 | 1988-12-29 | Zambeletti Spa L | Novel compounds |
| GB8916395D0 (en) * | 1989-07-18 | 1989-09-06 | Zambeletti Spa L | Pharmaceuticals |
| US5389638A (en) * | 1993-09-10 | 1995-02-14 | Abbott Laboratories | Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors |
| GB0225884D0 (en) * | 2002-11-06 | 2002-12-11 | Glaxo Group Ltd | Novel compounds |
| DK2935222T3 (en) | 2012-12-21 | 2019-01-07 | Epizyme Inc | PRMT5 INHIBITORS AND APPLICATIONS THEREOF |
| AU2016316436B2 (en) * | 2015-09-01 | 2021-04-29 | Merck Patent Gmbh | Method for the production of praziquantel and precursors thereof |
| WO2017066705A1 (en) * | 2015-10-14 | 2017-04-20 | Aquinnah Pharmaceuticals, Inc. | Compounds, compositions and methods of use against stress granules |
| RU2764243C2 (ru) | 2017-09-22 | 2022-01-14 | ДЖУБИЛАНТ ЭПИПЭД ЭлЭлСи | Гетероциклические соединения в качестве ингибиторов PAD |
| AU2018352142B2 (en) | 2017-10-18 | 2022-08-25 | Jubilant Epipad LLC | Imidazo-pyridine compounds as PAD inhibitors |
| US11629135B2 (en) | 2017-11-06 | 2023-04-18 | Jubilant Prodell Llc | Pyrimidine derivatives as inhibitors of PD1/PD-L1 activation |
| PT3704120T (pt) | 2017-11-24 | 2024-07-03 | Jubilant Episcribe Llc | Compostos heterocíclicos como inibidores de prmt5 |
| MX2020009517A (es) | 2018-03-13 | 2021-01-20 | Jubilant Prodel LLC | Compuestos biciclicos como inhibidores de la interaccion/activacio n de pdl/pd-l1. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2612503A (en) * | 1949-04-19 | 1952-09-30 | Smith Kline French Lab | Basic ether-substituted isoquinolines |
| US2640829A (en) * | 1950-11-10 | 1953-06-02 | Smith Kline French Lab | Isoquinolyl heterocyclic ethers |
| US3021331A (en) * | 1959-07-20 | 1962-02-13 | Pfizer & Co C | Azabenzopyridocolines |
| US3483206A (en) * | 1967-12-15 | 1969-12-09 | Ciba Geigy Corp | N-isoquinolylalkanoyl-n-arylamines |
| US3600394A (en) * | 1968-05-17 | 1971-08-17 | Searle & Co | 2-aminoalkyl-3-arylisocarbostyrils |
-
1973
- 1973-12-10 DE DE2361390A patent/DE2361390A1/de active Pending
-
1974
- 1974-11-29 IL IL46160A patent/IL46160A0/xx unknown
- 1974-12-05 SE SE7415247A patent/SE7415247L/xx unknown
- 1974-12-06 FR FR7440041A patent/FR2253522B1/fr not_active Expired
- 1974-12-06 CS CS748365A patent/CS188933B2/cs unknown
- 1974-12-06 BE BE151221A patent/BE823027A/xx unknown
- 1974-12-06 CA CA215,386A patent/CA1053675A/en not_active Expired
- 1974-12-09 GB GB5319174A patent/GB1447611A/en not_active Expired
- 1974-12-09 AT AT981974A patent/AT351026B/de not_active IP Right Cessation
- 1974-12-09 DK DK639674A patent/DK137007C/da active
- 1974-12-09 US US05/530,551 patent/US3985881A/en not_active Expired - Lifetime
- 1974-12-09 HU HU74ME00001812A patent/HU171483B/hu unknown
- 1974-12-09 JP JP49141945A patent/JPS5088077A/ja active Pending
- 1974-12-09 DD DD182514A patent/DD115666A5/xx unknown
- 1974-12-09 CH CH1632774A patent/CH605776A5/xx not_active IP Right Cessation
- 1974-12-09 ES ES432716A patent/ES432716A1/es not_active Expired
- 1974-12-09 ZA ZA00747820A patent/ZA747820B/xx unknown
- 1974-12-10 NL NL7416050A patent/NL7416050A/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| FR2253522B1 (cs) | 1978-06-30 |
| CA1053675A (en) | 1979-05-01 |
| DK137007C (da) | 1978-06-05 |
| IL46160A0 (en) | 1975-02-10 |
| BE823027A (fr) | 1975-06-06 |
| ES432716A1 (es) | 1977-03-01 |
| US3985881A (en) | 1976-10-12 |
| DK639674A (cs) | 1975-08-11 |
| AU7625774A (en) | 1976-06-10 |
| FR2253522A1 (cs) | 1975-07-04 |
| GB1447611A (en) | 1976-08-25 |
| CS188933B2 (en) | 1979-03-30 |
| JPS5088077A (cs) | 1975-07-15 |
| ATA981974A (de) | 1978-12-15 |
| SE7415247L (cs) | 1975-06-11 |
| NL7416050A (nl) | 1975-06-12 |
| CH605776A5 (cs) | 1978-10-13 |
| DD115666A5 (cs) | 1975-10-12 |
| AT351026B (de) | 1979-07-10 |
| DK137007B (da) | 1978-01-02 |
| HU171483B (hu) | 1978-01-28 |
| PL93405B1 (cs) | 1977-05-30 |
| DE2361390A1 (de) | 1975-06-19 |
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