ZA836358B - Intermediates useful in the preparation of 17,17-bis(substtituted thio)androstenes - Google Patents

Intermediates useful in the preparation of 17,17-bis(substtituted thio)androstenes

Info

Publication number: ZA836358B
Authority: ZA; South Africa
Prior art keywords: androstenes; hydrogen; preparation; substtituted; thio
Prior art date: 1982-09-09

Application number

ZA836358A

Other languages

English (en)

Inventor

Kannadikovilakom Varma Ravi

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-09-09

Filing date

1983-08-26

Publication date

1984-04-25

1983-08-26 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1984-04-25 Publication of ZA836358B publication Critical patent/ZA836358B/xx

Links

150000001443 androstenes Chemical class 0.000 title abstract 3
239000000543 intermediate Substances 0.000 title abstract 2
125000000446 sulfanediyl group Chemical group *S* 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 4
239000001257 hydrogen Substances 0.000 abstract 4
125000001589 carboacyl group Chemical group 0.000 abstract 3
229910052736 halogen Chemical group 0.000 abstract 3
150000002367 halogens Chemical group 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 2
-1 aroyloxyalkyl Chemical group 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
150000002431 hydrogen Chemical group 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000004356 hydroxy functional group Chemical group O* 0.000 abstract 2
125000004423 acyloxy group Chemical group 0.000 abstract 1
125000005041 acyloxyalkyl group Chemical group 0.000 abstract 1
125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000005078 alkoxycarbonylalkyl group Chemical group 0.000 abstract 1
125000006350 alkyl thio alkyl group Chemical group 0.000 abstract 1
230000003110 anti-inflammatory effect Effects 0.000 abstract 1
125000003435 aroyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000005110 aryl thio group Chemical group 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
125000004181 carboxyalkyl group Chemical group 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
125000004043 oxo group Chemical group O=* 0.000 abstract 1
150000003431 steroids Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/003—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Cosmetics (AREA)

ZA836358A 1982-09-09 1983-08-26 Intermediates useful in the preparation of 17,17-bis(substtituted thio)androstenes ZA836358B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/416,181 US4435326A (en)	1982-09-09	1982-09-09	Intermediates useful in the preparation of 17,17-bis(substituted thio)androstenes

Publications (1)

Publication Number	Publication Date
ZA836358B true ZA836358B (en)	1984-04-25

Family

ID=23648912

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA836358A ZA836358B (en)	1982-09-09	1983-08-26	Intermediates useful in the preparation of 17,17-bis(substtituted thio)androstenes

Country Status (12)

Country	Link
US (1)	US4435326A (da)
EP (1)	EP0105224B1 (da)
JP (1)	JPS5967299A (da)
AT (1)	ATE25089T1 (da)
AU (1)	AU558201B2 (da)
CA (1)	CA1248087A (da)
DE (1)	DE3369326D1 (da)
DK (1)	DK164873C (da)
HU (2)	HU189744B (da)
IE (1)	IE55719B1 (da)
NO (1)	NO159602C (da)
ZA (1)	ZA836358B (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4529548A (en) *	1984-05-07	1985-07-16	E. R. Squibb & Sons, Inc.	17β-(substituted thio)androstenes
US4529547A (en) *	1984-06-20	1985-07-16	E.R. Squibb & Sons, Inc.	17-(substituted thio)-17-(substituted dithio)androstenes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2949477A (en) *	1959-03-04	1960-08-16	Searle & Co	1, 3, 17-triacetoxyestra-1, 3, 5(10), 16-tetraene and congeners
US4091036A (en) *	1977-05-12	1978-05-23	E. R. Squibb & Sons, Inc.	17-Alkylthio (and arylthio)-1',2',3',4'-tetrahydroandrosteno [16 α, 17 α-b]naphthalenes and derivatives
US4094840A (en) *	1977-05-12	1978-06-13	E. R. Squibb & Sons, Inc.	17-Alkylthio (and arylthio) androsteno[16α,17α-b]benzodioxin-3-ones
US4133811A (en) *	1978-02-17	1979-01-09	E. R. Squibb & Sons, Inc.	13-Alkylthio (and arylthio)-11,17-epoxy-17-methyl-18-norandrostenes
US4146538A (en) *	1978-02-27	1979-03-27	E. R. Squibb & Sons, Inc.	17-Alkylthio (and arylthio) androsteno[17α,16α-b]benzopyran-3-ones and [16α,17α]naphthopyran-3-ones
US4361559A (en)	1981-08-20	1982-11-30	E. R. Squibb & Sons, Inc.	Antiinflammatory 17,17-bis (substituted thio) androstenes

1982
- 1982-09-09 US US06/416,181 patent/US4435326A/en not_active Expired - Fee Related
1983
- 1983-08-24 CA CA000435269A patent/CA1248087A/en not_active Expired
- 1983-08-25 AU AU18433/83A patent/AU558201B2/en not_active Ceased
- 1983-08-26 ZA ZA836358A patent/ZA836358B/xx unknown
- 1983-09-05 IE IE2080/83A patent/IE55719B1/en not_active IP Right Cessation
- 1983-09-08 HU HU833143A patent/HU189744B/hu not_active IP Right Cessation
- 1983-09-08 EP EP83108886A patent/EP0105224B1/en not_active Expired
- 1983-09-08 HU HU834616A patent/HU196432B/hu not_active IP Right Cessation
- 1983-09-08 DK DK407983A patent/DK164873C/da not_active IP Right Cessation
- 1983-09-08 JP JP58166447A patent/JPS5967299A/ja active Granted
- 1983-09-08 NO NO833208A patent/NO159602C/no unknown
- 1983-09-08 AT AT83108886T patent/ATE25089T1/de not_active IP Right Cessation
- 1983-09-08 DE DE8383108886T patent/DE3369326D1/de not_active Expired

Also Published As

Publication number	Publication date
AU1843383A (en)	1984-03-15
AU558201B2 (en)	1987-01-22
DK164873C (da)	1993-01-11
JPH0439478B2 (da)	1992-06-29
ATE25089T1 (de)	1987-02-15
JPS5967299A (ja)	1984-04-16
DE3369326D1 (en)	1987-02-26
HU189744B (en)	1986-07-28
CA1248087A (en)	1989-01-03
HU196432B (en)	1988-11-28
NO159602B (no)	1988-10-10
EP0105224A2 (en)	1984-04-11
DK407983A (da)	1984-03-10
NO833208L (no)	1984-03-12
EP0105224A3 (en)	1984-08-01
DK164873B (da)	1992-08-31
NO159602C (no)	1989-01-18
US4435326A (en)	1984-03-06
IE55719B1 (en)	1991-01-02
EP0105224B1 (en)	1987-01-21
IE832080L (en)	1984-03-09
DK407983D0 (da)	1983-09-08

Publication	Publication Date	Title
PH21785A (en)	1988-02-24	Substituted androsta-1,4-diene-3,17-dione derivatives
IL66564A (en)	1986-03-31	Pharmaceutical compositions containing 17,17-bis(substituted thio)androstenes and certain novel 17,17-bis(substituted thio)-androstenes
UA6044A1 (uk)	1994-12-29	Спосіб одержання метіленових похідних андроста-1,4 -діен-3,17-діона
IE843260L (en)	1985-06-21	Anti-inflammatory oxicams
AU562646B2 (en)	1987-06-18	1-alkyl-androsta-1, 4-diene-3, 17-diones
TR199501327A3 (da)	1996-06-21
ZA836358B (en)	1984-04-25	Intermediates useful in the preparation of 17,17-bis(substtituted thio)androstenes
DE3567876D1 (en)	1989-03-02	Process and intermediates for the preparation of 17alpha-hydroxyprogesterones and corticoids from an enol steroid
AU562027B2 (en)	1987-05-28	Androstene-17-dithioketals, and 1,2-and 6,7-dehydro derivatives
GR3024298T3 (en)	1997-10-31	Tase inhibitors 2-g(b),19-methyleneamino bridged steroids as aroma
IL80176A0 (en)	1986-12-31	1-methyl-15alpha-alkylandrosta-1,4-diene-3,17-dione derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
GB1420831A (en)	1976-01-14	Compositions incorporating anabolic and estrogenic steroids
IE861677L (en)	1987-01-24	11-methylene-15-ene steroids
BA97185B1 (bs)	1999-08-02	Postupak za dobijanje supstituisanih androsta-1,4-dien-3,17-diona