ZA841763B - A method for detecting a polynucleotide sequence and labelled polynucleotides useful therein - Google Patents

A method for detecting a polynucleotide sequence and labelled polynucleotides useful therein

Info

Publication number
ZA841763B
ZA841763B ZA841763A ZA841763A ZA841763B ZA 841763 B ZA841763 B ZA 841763B ZA 841763 A ZA841763 A ZA 841763A ZA 841763 A ZA841763 A ZA 841763A ZA 841763 B ZA841763 B ZA 841763B
Authority
ZA
South Africa
Prior art keywords
detecting
polynucleotide sequence
polynucleotides useful
labelled polynucleotides
labelled
Prior art date
Application number
ZA841763A
Other languages
English (en)
Inventor
Malcolm Alan David Blair
Lesley Nicolas Jean
Original Assignee
Blair Malcolm A D
Lesley Nicolas Jean
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Blair Malcolm A D, Lesley Nicolas Jean filed Critical Blair Malcolm A D
Publication of ZA841763B publication Critical patent/ZA841763B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C12Q1/683—Hybridisation assays for detection of mutation or polymorphism involving restriction enzymes, e.g. restriction fragment length polymorphism [RFLP]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
ZA841763A 1983-03-09 1984-03-09 A method for detecting a polynucleotide sequence and labelled polynucleotides useful therein ZA841763B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838306426A GB8306426D0 (en) 1983-03-09 1983-03-09 Detecting polynucleotide sequence

Publications (1)

Publication Number Publication Date
ZA841763B true ZA841763B (en) 1984-10-31

Family

ID=10539218

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA841763A ZA841763B (en) 1983-03-09 1984-03-09 A method for detecting a polynucleotide sequence and labelled polynucleotides useful therein

Country Status (8)

Country Link
EP (1) EP0124221A1 (fr)
JP (1) JPS60500651A (fr)
AU (1) AU572505B2 (fr)
DK (1) DK532484A (fr)
GB (1) GB8306426D0 (fr)
NZ (1) NZ207454A (fr)
WO (1) WO1984003520A1 (fr)
ZA (1) ZA841763B (fr)

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CA1228811A (fr) 1983-05-05 1987-11-03 Robert G. Pergolizzi Methode d'analyse utilisant des sequences de polynucleotides
FI71768C (fi) * 1984-02-17 1987-02-09 Orion Yhtymae Oy Foerbaettrade nykleinsyrareagenser och foerfarande foer deras framstaellning.
EP0154505B1 (fr) * 1984-02-28 1992-09-30 Ortho Diagnostic Systems Inc. Diagnostic d'anomalies d'un gène par rapport à la carte d'enzyme de restriction utilisant l'hybridation en sandwich à cette fin
GB8405437D0 (en) * 1984-03-01 1984-04-04 Amersham Int Plc Detecting polynucleotide sequences
US4748111A (en) * 1984-03-12 1988-05-31 Molecular Diagnostics, Inc. Nucleic acid-protein conjugate used in immunoassay
US4766064A (en) * 1984-05-07 1988-08-23 Allied Corporation Displacement polynucleotide assay employing polyether and diagnostic kit
CA1254114A (fr) * 1984-05-07 1989-05-16 Allied Corporation Epreuve de deplacement de polynucleotides utilisant une proteine de recombinaison et une trousse de diagnostic
US4766062A (en) * 1984-05-07 1988-08-23 Allied Corporation Displacement polynucleotide assay method and polynucleotide complex reagent therefor
IL75142A0 (en) * 1984-05-15 1985-09-29 Smithkline Beckman Corp Polynucleotide hybridization probes
US4820630A (en) * 1984-11-23 1989-04-11 Digene Diagnostics, Incorporated Assay for nucleic acid sequences, particularly genetic lesions, using interactive labels
US4670379A (en) * 1984-12-19 1987-06-02 E. I. Du Pont De Nemours And Company Polynucleotide hydridization assays employing catalyzed luminescence
GB2179448B (en) * 1984-12-19 1989-06-07 Blair Malcolm A D Improved sandwich hybridisation technique for the detection of nucleotide sequences
GB8432118D0 (en) * 1984-12-19 1985-01-30 Malcolm A D B Sandwich hybridisation technique
FI72146C (fi) * 1985-01-02 1987-04-13 Orion Yhtymae Oy Foerfarande foer identifiering av nukleinsyror.
US5026840A (en) * 1985-01-10 1991-06-25 Molecular Diagnostics, Inc. Photochemical nucleic acid-labeling reagent having a polyalklamine spacer
ATE40572T1 (de) * 1985-01-10 1989-02-15 Molecular Diagnostics Inc Photochemisches verfahren zum markieren von nucleinsaeuren zum nachweis in hybridisationsproben.
US5851767A (en) 1985-03-04 1998-12-22 The Regents Of The University Of California Detection of prokaryotic organism by DNA hybridization
GB8509880D0 (en) * 1985-04-17 1985-05-22 Ici Plc Testing device
US4735897A (en) * 1985-05-02 1988-04-05 Allied Corporation Method and kit for detecting polyriboadenosine segments and messenger RNA
US4767699A (en) * 1985-05-02 1988-08-30 Allied Corporation Diagnostic reagent, kit and method employing polynucleotide displacement, separation, enzymatic cleavage and adenosine phosphate detection
EP0204510B1 (fr) * 1985-05-31 1991-07-10 Amoco Corporation Amplification de signaux d'hybridation par l'emploi de brins d'ADN complémentaires
US4751177A (en) * 1985-06-13 1988-06-14 Amgen Methods and kits for performing nucleic acid hybridization assays
EP0219842A1 (fr) * 1985-10-23 1987-04-29 Allied Corporation Essai d'acide nucléique utilisant inhibition ou concurrence de segment-paire
US4868105A (en) * 1985-12-11 1989-09-19 Chiron Corporation Solution phase nucleic acid sandwich assay
US4882269A (en) * 1985-12-13 1989-11-21 Princeton University Amplified hybridization assay
US4925785A (en) * 1986-03-07 1990-05-15 Biotechnica Diagnostics, Inc. Nucleic acid hybridization assays
EP0244207B1 (fr) * 1986-04-30 1991-07-31 Toray Industries, Inc. Méthode de détection et appareil
AU1070588A (en) * 1987-01-30 1988-08-04 Diagnostic Products Corporation Measuring anti-dna antibodies
US4847193A (en) * 1987-06-18 1989-07-11 Gene-Trak Systems Signal amplification in an assay employing a piezoelectric oscillator
EP0305145A3 (fr) * 1987-08-24 1990-05-02 Ortho Diagnostic Systems Inc. Méthodes et sondes pour détecter des acides nucléiques
EP0304845A3 (fr) * 1987-08-28 1991-03-06 Profile Diagnostic Sciences Inc. Procédé et composition pour déterminer l'expression des gènes
DE3732145A1 (de) * 1987-09-24 1989-04-06 Merck Patent Gmbh Verfahren und reagenz zur durchfuehrung von hybridisierungsreaktionen
US4962029A (en) * 1987-10-02 1990-10-09 Cetus Corporation Covalent oligonucleotide-horseradish peroxidase conjugate
JPH0630574B2 (ja) * 1987-10-02 1994-04-27 シタス コーポレイション オリゴヌクレオチド‐西洋ワサビパーオキシダーゼ共有結合接合体
US5359100A (en) * 1987-10-15 1994-10-25 Chiron Corporation Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers
US5124246A (en) * 1987-10-15 1992-06-23 Chiron Corporation Nucleic acid multimers and amplified nucleic acid hybridization assays using same
FR2644163B2 (fr) * 1988-07-13 1994-09-30 Bioprobe Systems Sa Procede de marquage d'une sonde nucleique et trousse de reactifs pour la mise en oeuvre de ce procede
FR2634211B1 (fr) * 1988-07-13 1992-06-26 Lebacq Philippe Procede de marquage d'une sonde nucleique et trousse de reactifs pour la mise en oeuvre de ce procede
US5324829A (en) * 1988-12-16 1994-06-28 Ortho Diagnostic Systems, Inc. High specific activity nucleic acid probes having target recognition and signal generating moieties
ATE193019T1 (de) * 1989-10-13 2000-06-15 Zeneca Ltd Sonden
GB8927365D0 (en) * 1989-12-04 1990-01-31 Ici Plc Reagent
IE910081A1 (en) 1990-01-10 1991-07-17 Chiron Corp The use of DNA-dependent RNA polymerase transcripts as¹reporter molecules for signal amplification in nucleic acid¹hybridization assays
US5629153A (en) * 1990-01-10 1997-05-13 Chiron Corporation Use of DNA-dependent RNA polymerase transcripts as reporter molecules for signal amplification in nucleic acid hybridization assays
US5200314A (en) * 1990-03-23 1993-04-06 Chiron Corporation Polynucleotide capture assay employing in vitro amplification
AU7429591A (en) * 1990-04-18 1991-10-24 Gene-Trak Systems Nucleic acid probes for the detection of giardia lamblia
WO1992000989A1 (fr) * 1990-07-10 1992-01-23 Imperial Chemical Industries Plc Procede de marquage non-isotopique d'acide nucleique
WO1995014106A2 (fr) * 1993-11-17 1995-05-26 Id Biomedical Corporation Detection cyclique par scission de sondes de sequences d'acides nucleiques
EP0938588B1 (fr) * 1996-07-12 2003-02-12 TM Technologies Inc. Procede d'amplification de signaux
US5853993A (en) * 1996-10-21 1998-12-29 Hewlett-Packard Company Signal enhancement method and kit
EP1816200B1 (fr) 1997-12-11 2016-03-09 Merial Virus de syndrome de dépérissement post-sevrage pour cochons
JP3795751B2 (ja) 1997-12-11 2006-07-12 ユニバーシティ オブ サスカッチェワン ブタからの離乳後多全身系消耗症候群ウイルス
US6642001B1 (en) 1999-07-13 2003-11-04 Whitehead Institute For Biomedical Research Generic SBE-FRET protocol
US7919276B1 (en) * 2000-02-22 2011-04-05 Mount Sinai School Of Medicine ZA loops of bromodomains
US20040161741A1 (en) * 2001-06-30 2004-08-19 Elazar Rabani Novel compositions and processes for analyte detection, quantification and amplification
WO2017097973A1 (fr) * 2015-12-09 2017-06-15 Universitaet Konstanz Nucléosides modifiés

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede
DK163123C (da) * 1978-05-30 1992-06-09 Du Pont Benzensulfonylurinstoffer til anvendelse som herbicider eller plantevaekstregulatorer, praeparat indeholdende dem samt deres anvendelse
CA1180647A (fr) * 1981-07-17 1985-01-08 Cavit Akin Methode de diagnostic d'hybridation de polynucleotides par emission de lumiere
CA1190838A (fr) * 1981-07-17 1985-07-23 Cavit Akin Procede de diagnostic d'hybridation

Also Published As

Publication number Publication date
JPS60500651A (ja) 1985-05-09
AU572505B2 (en) 1988-05-12
NZ207454A (en) 1987-05-29
WO1984003520A1 (fr) 1984-09-13
EP0124221A1 (fr) 1984-11-07
DK532484D0 (da) 1984-11-08
GB8306426D0 (en) 1983-04-13
AU2695184A (en) 1984-09-28
DK532484A (da) 1984-11-08

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