ZA849944B - 5-fluoro-3-oxa-prostacyclin compounds - Google Patents

5-fluoro-3-oxa-prostacyclin compounds

Info

Publication number
ZA849944B
ZA849944B ZA849944A ZA849944A ZA849944B ZA 849944 B ZA849944 B ZA 849944B ZA 849944 A ZA849944 A ZA 849944A ZA 849944 A ZA849944 A ZA 849944A ZA 849944 B ZA849944 B ZA 849944B
Authority
ZA
South Africa
Prior art keywords
oxa
fluoro
prostacyclin compounds
prostacyclin
compounds
Prior art date
Application number
ZA849944A
Other languages
English (en)
Inventor
Stevan Wakefield Djuric
Leland Jew Chinn
Kurt Joachim Rorig
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of ZA849944B publication Critical patent/ZA849944B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
ZA849944A 1983-12-23 1984-12-20 5-fluoro-3-oxa-prostacyclin compounds ZA849944B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/565,250 US4579958A (en) 1983-12-23 1983-12-23 5-fluoro-3-oxa-6,7-didehydro-PGI1 compounds

Publications (1)

Publication Number Publication Date
ZA849944B true ZA849944B (en) 1986-02-26

Family

ID=24257800

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA849944A ZA849944B (en) 1983-12-23 1984-12-20 5-fluoro-3-oxa-prostacyclin compounds

Country Status (6)

Country Link
US (1) US4579958A (fr)
EP (1) EP0148010A3 (fr)
JP (1) JPS60222475A (fr)
AU (1) AU3696184A (fr)
ES (1) ES8604508A1 (fr)
ZA (1) ZA849944B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4611065A (en) * 1985-01-25 1986-09-09 G. D. Searle & Co. Method for preparing 5-fluoroprostacyclins
DE3526362A1 (de) * 1985-07-19 1987-01-22 Schering Ag Prostacycline, ihre analoga oder prostaglandine und thromboxanantagonisten zur behandlung von thrombotischen und thromboembolischen krankheitsbildern
IL87116A (en) 1987-07-17 1993-03-15 Schering Ag 9-halogen-(z)-prostaglandin derivatives and pharmaceutical compositions containing the same
AU634871B2 (en) * 1990-03-20 1993-03-04 Banyu Pharmaceutical Co., Ltd. Substituted amine derivatives having anti-hyperlipemia activity
RU2695274C3 (ru) 1999-10-15 2020-11-09 Сукампо Аг Новые композиции и способы их стабилизации
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3923861A (en) * 1969-07-29 1975-12-02 Upjohn Co 3-Oxa prostaglandin F{331 -type compounds
JPS56501319A (fr) * 1979-10-10 1981-09-17
US4324730A (en) * 1979-10-10 1982-04-13 The University Of Chicago Certain fluorine substituted PGI2 compounds
PT74691B (en) * 1981-04-02 1983-10-26 Searle & Co Process for preparing 5 fluoro pgi2 compounds

Also Published As

Publication number Publication date
US4579958A (en) 1986-04-01
ES538867A0 (es) 1986-02-01
JPS60222475A (ja) 1985-11-07
EP0148010A3 (fr) 1985-12-27
EP0148010A2 (fr) 1985-07-10
AU3696184A (en) 1985-07-04
ES8604508A1 (es) 1986-02-01

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