ZA851536B - Brain-specific analogues of centrally acting amines - Google Patents
Brain-specific analogues of centrally acting aminesInfo
- Publication number
- ZA851536B ZA851536B ZA851536A ZA851536A ZA851536B ZA 851536 B ZA851536 B ZA 851536B ZA 851536 A ZA851536 A ZA 851536A ZA 851536 A ZA851536 A ZA 851536A ZA 851536 B ZA851536 B ZA 851536B
- Authority
- ZA
- South Africa
- Prior art keywords
- brain
- centrally acting
- specific analogues
- acting amines
- amines
- Prior art date
Links
- 150000001412 amines Chemical class 0.000 title 1
- 210000004556 brain Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/559—Redox delivery systems, e.g. dihydropyridine pyridinium salt redox systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Cephalosporin Compounds (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58480084A | 1984-02-29 | 1984-02-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA851536B true ZA851536B (en) | 1986-10-29 |
Family
ID=24338848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA851536A ZA851536B (en) | 1984-02-29 | 1985-02-28 | Brain-specific analogues of centrally acting amines |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0174342B1 (it) |
| JP (1) | JPS61501562A (it) |
| AU (1) | AU593209B2 (it) |
| DE (1) | DE3574869D1 (it) |
| IT (1) | IT1182713B (it) |
| WO (1) | WO1985003937A1 (it) |
| ZA (1) | ZA851536B (it) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5079366A (en) * | 1987-04-07 | 1992-01-07 | University Of Florida | Quarternary pyridinium salts |
| US4888427A (en) * | 1987-04-07 | 1989-12-19 | University Of Florida | Amino acids containing dihydropyridine ring systems for site-specific delivery of peptides to the brain |
| US5002935A (en) * | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| US5017566A (en) * | 1987-12-30 | 1991-05-21 | University Of Florida | Redox systems for brain-targeted drug delivery |
| US5177064A (en) * | 1990-07-13 | 1993-01-05 | University Of Florida | Targeted drug delivery via phosphonate derivatives |
| IL106998A0 (en) * | 1992-09-17 | 1993-12-28 | Univ Florida | Brain-enhanced delivery of neuroactive peptides by sequential metabolism |
| WO1999012572A1 (en) | 1997-09-10 | 1999-03-18 | University Of Florida | Compounds and method for the prevention and treatment of diabetic retinopathy |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH335521A (de) * | 1955-06-02 | 1959-01-15 | Cilag Ag | Verfahren zur Herstellung neuer quaternärer Salze |
| AU538526B2 (en) * | 1980-07-01 | 1984-08-16 | Ici Australia Limited | Isoquinoline derivatives |
| EP0221588A3 (en) * | 1982-05-18 | 1988-09-21 | University Of Florida | Brain-specific drug delivery |
| US4519289A (en) * | 1984-01-09 | 1985-05-28 | Gauger Gary L | Adjustable circumference floor tom stand |
-
1985
- 1985-02-15 WO PCT/US1985/000236 patent/WO1985003937A1/en not_active Ceased
- 1985-02-15 JP JP60501014A patent/JPS61501562A/ja active Pending
- 1985-02-15 AU AU39971/85A patent/AU593209B2/en not_active Ceased
- 1985-02-15 DE DE8585901226T patent/DE3574869D1/de not_active Expired - Lifetime
- 1985-02-15 EP EP85901226A patent/EP0174342B1/en not_active Expired
- 1985-02-28 IT IT47751/85A patent/IT1182713B/it active
- 1985-02-28 ZA ZA851536A patent/ZA851536B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0174342A1 (en) | 1986-03-19 |
| IT1182713B (it) | 1987-10-05 |
| EP0174342B1 (en) | 1989-12-20 |
| DE3574869D1 (de) | 1990-01-25 |
| WO1985003937A1 (en) | 1985-09-12 |
| IT8547751A0 (it) | 1985-02-28 |
| AU593209B2 (en) | 1990-02-08 |
| JPS61501562A (ja) | 1986-07-31 |
| IT8547751A1 (it) | 1986-08-28 |
| AU3997185A (en) | 1985-09-24 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PL256012A1 (en) | Method of obtaining peptides | |
| DE3571613D1 (en) | Preparation of (threo)-1-aryl-2-acylamido-3-fluoro-1-propanols | |
| EP0155193A3 (en) | Methods of assay | |
| PL253107A1 (en) | Method of obtaining novel 2/n-substituted guanidine/-4-heteroarylthiazoles | |
| IL75533A (en) | Preparation of heteroaryloxyacetamides | |
| GB8509322D0 (en) | Determination of microconstituent | |
| ZA851536B (en) | Brain-specific analogues of centrally acting amines | |
| GB8704890D0 (en) | Protection of proteins | |
| GB8507789D0 (en) | Preparation of 2-amino-s-triazines | |
| IL76989A0 (en) | Preparation of isocyanates | |
| JPS6416730A (en) | Manufacture of amide | |
| IL76249A0 (en) | Preparation of fluoroformates | |
| GB8517881D0 (en) | Preparation of elixir | |
| DE3566540D1 (en) | Preparation of fluoropyridines | |
| EP0155135A3 (en) | Methods of assay | |
| GB2160204B (en) | Preparation of amine derivatives | |
| PT79823B (en) | Process for the preparation of n-(naphtyl-alquil)-hydroxilamines | |
| GB8520403D0 (en) | Preparation of aminolactone | |
| GB8422162D0 (en) | Preparation of alkyfurans | |
| IL76216A0 (en) | Preparation of sulphonylisoureas and-thioureas | |
| GB8429529D0 (en) | Stabilization of amines | |
| GB8432449D0 (en) | Preparation of n-acyl-derivatives of aspartame | |
| PL250251A1 (en) | Method of obtaining novel peptide analogues of encephaline | |
| NZ227556A (en) | 1-alkoxy-1-methylethoxy amines | |
| GB8416158D0 (en) | Amines |