IT8547751A1 - Analoghi cerebro-specifici di ammine ad azione centrale - Google Patents
Analoghi cerebro-specifici di ammine ad azione centraleInfo
- Publication number
- IT8547751A1 IT8547751A1 IT1985A47751A IT4775185A IT8547751A1 IT 8547751 A1 IT8547751 A1 IT 8547751A1 IT 1985A47751 A IT1985A47751 A IT 1985A47751A IT 4775185 A IT4775185 A IT 4775185A IT 8547751 A1 IT8547751 A1 IT 8547751A1
- Authority
- IT
- Italy
- Prior art keywords
- admines
- cerebro
- central action
- specific analogs
- analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/559—Redox delivery systems, e.g. dihydropyridine pyridinium salt redox systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Cephalosporin Compounds (AREA)
- Quinoline Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58480084A | 1984-02-29 | 1984-02-29 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| IT8547751A0 IT8547751A0 (it) | 1985-02-28 |
| IT8547751A1 true IT8547751A1 (it) | 1986-08-28 |
| IT1182713B IT1182713B (it) | 1987-10-05 |
Family
ID=24338848
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT47751/85A IT1182713B (it) | 1984-02-29 | 1985-02-28 | Analoghi cerebro-specifici di ammine ad azione centrale |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0174342B1 (it) |
| JP (1) | JPS61501562A (it) |
| AU (1) | AU593209B2 (it) |
| DE (1) | DE3574869D1 (it) |
| IT (1) | IT1182713B (it) |
| WO (1) | WO1985003937A1 (it) |
| ZA (1) | ZA851536B (it) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5079366A (en) * | 1987-04-07 | 1992-01-07 | University Of Florida | Quarternary pyridinium salts |
| US4888427A (en) * | 1987-04-07 | 1989-12-19 | University Of Florida | Amino acids containing dihydropyridine ring systems for site-specific delivery of peptides to the brain |
| US5002935A (en) * | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| US5017566A (en) * | 1987-12-30 | 1991-05-21 | University Of Florida | Redox systems for brain-targeted drug delivery |
| US5177064A (en) * | 1990-07-13 | 1993-01-05 | University Of Florida | Targeted drug delivery via phosphonate derivatives |
| IL106998A0 (en) * | 1992-09-17 | 1993-12-28 | Univ Florida | Brain-enhanced delivery of neuroactive peptides by sequential metabolism |
| WO1999012572A1 (en) | 1997-09-10 | 1999-03-18 | University Of Florida | Compounds and method for the prevention and treatment of diabetic retinopathy |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH335521A (de) * | 1955-06-02 | 1959-01-15 | Cilag Ag | Verfahren zur Herstellung neuer quaternärer Salze |
| AU538526B2 (en) * | 1980-07-01 | 1984-08-16 | Ici Australia Limited | Isoquinoline derivatives |
| EP0221588A3 (en) * | 1982-05-18 | 1988-09-21 | University Of Florida | Brain-specific drug delivery |
| US4519289A (en) * | 1984-01-09 | 1985-05-28 | Gauger Gary L | Adjustable circumference floor tom stand |
-
1985
- 1985-02-15 WO PCT/US1985/000236 patent/WO1985003937A1/en not_active Ceased
- 1985-02-15 JP JP60501014A patent/JPS61501562A/ja active Pending
- 1985-02-15 AU AU39971/85A patent/AU593209B2/en not_active Ceased
- 1985-02-15 DE DE8585901226T patent/DE3574869D1/de not_active Expired - Lifetime
- 1985-02-15 EP EP85901226A patent/EP0174342B1/en not_active Expired
- 1985-02-28 IT IT47751/85A patent/IT1182713B/it active
- 1985-02-28 ZA ZA851536A patent/ZA851536B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0174342A1 (en) | 1986-03-19 |
| IT1182713B (it) | 1987-10-05 |
| EP0174342B1 (en) | 1989-12-20 |
| DE3574869D1 (de) | 1990-01-25 |
| WO1985003937A1 (en) | 1985-09-12 |
| ZA851536B (en) | 1986-10-29 |
| IT8547751A0 (it) | 1985-02-28 |
| AU593209B2 (en) | 1990-02-08 |
| JPS61501562A (ja) | 1986-07-31 |
| AU3997185A (en) | 1985-09-24 |
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