ZA851548B - Pharmaceutical product for the treatment of hypertension and thromboembolic diseases - Google Patents
Pharmaceutical product for the treatment of hypertension and thromboembolic diseasesInfo
- Publication number
- ZA851548B ZA851548B ZA851548A ZA851548A ZA851548B ZA 851548 B ZA851548 B ZA 851548B ZA 851548 A ZA851548 A ZA 851548A ZA 851548 A ZA851548 A ZA 851548A ZA 851548 B ZA851548 B ZA 851548B
- Authority
- ZA
- South Africa
- Prior art keywords
- hypertension
- treatment
- thromboembolic diseases
- pharmaceutical product
- pyridazinone
- Prior art date
Links
- 206010020772 Hypertension Diseases 0.000 title abstract 3
- 208000001435 Thromboembolism Diseases 0.000 title abstract 3
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 229940127557 pharmaceutical product Drugs 0.000 title abstract 2
- 239000013543 active substance Substances 0.000 abstract 2
- NPFVRBCDMFKOPY-UHFFFAOYSA-N 3-(4-imidazol-1-ylthiophen-2-yl)-4-methyl-4,5-dihydro-1h-pyridazin-6-one Chemical compound CC1CC(=O)NN=C1C1=CC(N2C=NC=C2)=CS1 NPFVRBCDMFKOPY-UHFFFAOYSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843407509 DE3407509A1 (de) | 1984-03-01 | 1984-03-01 | Neue arzneimittelkombination zur behandlung von bluthochdruck und thromboembolischen erkrankungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA851548B true ZA851548B (en) | 1985-10-30 |
Family
ID=6229261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA851548A ZA851548B (en) | 1984-03-01 | 1985-02-28 | Pharmaceutical product for the treatment of hypertension and thromboembolic diseases |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US4661487A (da) |
| EP (1) | EP0156163B1 (da) |
| JP (1) | JPS60202819A (da) |
| AT (1) | ATE38470T1 (da) |
| DE (2) | DE3407509A1 (da) |
| DK (1) | DK93485A (da) |
| GR (1) | GR850473B (da) |
| ZA (1) | ZA851548B (da) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3535170A1 (de) * | 1985-10-02 | 1987-04-16 | Basf Ag | Verwendung von 2-aryl-3,4-diaza-bicyclo(4.n.0)alken-(2)-onen-(5) zur behandlung der herzinsuffizienz |
| DE3805635A1 (de) * | 1988-02-24 | 1989-09-07 | Thomae Gmbh Dr K | Verwendung von benzimidazolen zur herstellung eines arzneimittels mit antiischaemischen wirkungen am herzen und dessen kombinationen mit ss-blockern oder bradycardica |
| EP0375247B1 (en) * | 1988-12-21 | 1996-02-28 | Texas Instruments Incorporated | Metastable tolerant latch |
| US20110015246A2 (en) * | 2005-03-14 | 2011-01-20 | Agean Llc | Lofexidine enantiomers for use as a treatment for cns disease and pathologies and its chiral synthesis |
| US20090246256A1 (en) * | 2008-03-27 | 2009-10-01 | Al-Ghananeem Abeer M | Compositions and Methods for Transmucosal Delivery of Lofexidine |
| WO2010075275A1 (en) * | 2008-12-23 | 2010-07-01 | Usworldmeds Llc | Selective release of non-racemic mixtures of two enantiomers from tablets and capsules |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1795843U (de) | 1959-06-12 | 1959-09-17 | Johannes Schlueter Chem Fab | Bohnergeraet mit vorratsbehaelter und einrichtung zur portionsweisen abgabe von fluessigwachs. |
| HU190412B (en) * | 1981-09-17 | 1986-09-29 | Warner-Lambert Co,Us | Process for producing substituted 4,5-dihiydro-6-bracket-substituted-bracket closed-phenyl-3-bracket-2h-bracket closed-pyridazinones and 6-bracket-substituted-bracket closed-phenyl-3-bracket-2h-bracket closed-pyridazinones |
| DE3149009A1 (de) | 1981-12-10 | 1983-06-23 | A. Nattermann & Cie GmbH, 5000 Köln | (-)-2-(1-(2,6-dichlorphenoxy)-ethyl)-1,3-diazacyclopent-2-en, dessen herstellung und seine verwendung in pharmazeutischen praeparaten |
| DE3212304A1 (de) * | 1982-04-02 | 1983-10-06 | Nattermann A & Cie | Imidazolylphenyl-tetrahydropyridazine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate |
| DE3241102A1 (de) * | 1982-11-06 | 1984-05-10 | A. Nattermann & Cie GmbH, 5000 Köln | Imidazolylalkylthienyl-tetrahydropyridazine und verfahren zu ihrer herstellung |
-
1984
- 1984-03-01 DE DE19843407509 patent/DE3407509A1/de not_active Withdrawn
-
1985
- 1985-02-21 EP EP85101863A patent/EP0156163B1/en not_active Expired
- 1985-02-21 AT AT85101863T patent/ATE38470T1/de not_active IP Right Cessation
- 1985-02-21 DE DE8585101863T patent/DE3566079D1/de not_active Expired
- 1985-02-22 GR GR850473A patent/GR850473B/el unknown
- 1985-02-26 US US06/705,668 patent/US4661487A/en not_active Expired - Fee Related
- 1985-02-28 JP JP60037801A patent/JPS60202819A/ja active Pending
- 1985-02-28 ZA ZA851548A patent/ZA851548B/xx unknown
- 1985-02-28 DK DK93485A patent/DK93485A/da not_active Application Discontinuation
-
1987
- 1987-01-21 US US07/005,622 patent/US4746660A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3407509A1 (de) | 1985-09-05 |
| ATE38470T1 (de) | 1988-11-15 |
| US4661487A (en) | 1987-04-28 |
| DK93485A (da) | 1985-09-02 |
| GR850473B (da) | 1985-05-31 |
| EP0156163A1 (en) | 1985-10-02 |
| US4746660A (en) | 1988-05-24 |
| DE3566079D1 (en) | 1988-12-15 |
| DK93485D0 (da) | 1985-02-28 |
| EP0156163B1 (en) | 1988-11-09 |
| JPS60202819A (ja) | 1985-10-14 |
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