ZA854018B - Use of hydroxyindole derivatives in lowering blood pressure - Google Patents

Use of hydroxyindole derivatives in lowering blood pressure

Info

Publication number: ZA854018B
Authority: ZA; South Africa
Prior art keywords: blood pressure; lowering blood; hydroxyindole; hydroxyindole derivatives; derivatives
Prior art date: 1984-05-28

Application number

ZA854018A

Other languages

English (en)

Inventor

Hans-Heinrich Hausberg

Henning Boettcher

Christoph Seyfried

Rolf Bergmann

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-05-28

Filing date

1985-05-27

Publication date

1986-01-29

1985-05-27 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

1986-01-29 Publication of ZA854018B publication Critical patent/ZA854018B/xx

Links

JHFAEUICJHBVHB-UHFFFAOYSA-N 1h-indol-2-ol Chemical class C1=CC=C2NC(O)=CC2=C1 JHFAEUICJHBVHB-UHFFFAOYSA-N 0.000 title abstract 2
230000036772 blood pressure Effects 0.000 title abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

ZA854018A 1984-05-28 1985-05-27 Use of hydroxyindole derivatives in lowering blood pressure ZA854018B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19843419935 DE3419935A1 (de)	1984-05-28	1984-05-28	Verwendung von hydroxyindolderivaten bei der senkung des blutdrucks

Publications (1)

Publication Number	Publication Date
ZA854018B true ZA854018B (en)	1986-01-29

Family

ID=6237075

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA854018A ZA854018B (en)	1984-05-28	1985-05-27	Use of hydroxyindole derivatives in lowering blood pressure

Country Status (6)

Country	Link
US (1)	US4711893A (fr)
EP (1)	EP0166183B1 (fr)
JP (1)	JPS60258117A (fr)
AT (1)	ATE57095T1 (fr)
DE (2)	DE3419935A1 (fr)
ZA (1)	ZA854018B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3604949A1 (de) *	1986-02-17	1987-08-20	Merck Patent Gmbh	Hydroxyindolester
DE3614758A1 (de) *	1986-04-30	1987-11-05	Merck Patent Gmbh	Indolderivat
AU611469B2 (en) *	1987-08-13	1991-06-13	Glaxo Group Limited	Indole derivatives
GB8719167D0 (en) *	1987-08-13	1987-09-23	Glaxo Group Ltd	Chemical compounds
USH734H (en)	1988-03-07	1990-02-06	E. R. Squibb & Sons, Inc.	Method for inhibiting onset of or treating migraine headaches employing an ACE inhibitor
GB8819024D0 (en) *	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
DE3907974A1 (de) *	1989-03-11	1990-09-13	Merck Patent Gmbh	Indolderivate
US5356913A (en) *	1990-02-09	1994-10-18	The Upjohn Company	Use of insulin sensitizing agents to treat hypertension
WO1991012003A1 (fr) *	1990-02-09	1991-08-22	The Upjohn Company	Utilisation d'agents de sensibilisation a l'insuline afin de traiter l'hypertension
AR004229A1 (es) *	1995-11-06	1998-11-04	Wyeth Corp	Derivados indolalquilo de benzodioxanmetilamina y su uso para preparar medicamentos
US10316025B2 (en)	2015-06-03	2019-06-11	Sunshine Lake Pharma Co., Ltd.	Substituted piperazine compounds and methods of use and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0007399B1 (fr) *	1978-06-24	1982-01-20	MERCK PATENT GmbH	Indolylalcoylamines, préparations pharmaceutiques les contenant et procédé pour leur fabrication

1984
- 1984-05-28 DE DE19843419935 patent/DE3419935A1/de not_active Withdrawn
1985
- 1985-05-18 DE DE8585106121T patent/DE3579955D1/de not_active Expired - Fee Related
- 1985-05-18 AT AT85106121T patent/ATE57095T1/de not_active IP Right Cessation
- 1985-05-18 EP EP85106121A patent/EP0166183B1/fr not_active Expired - Lifetime
- 1985-05-27 ZA ZA854018A patent/ZA854018B/xx unknown
- 1985-05-28 JP JP60113319A patent/JPS60258117A/ja active Pending
1986
- 1986-09-16 US US06/907,909 patent/US4711893A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE3419935A1 (de)	1985-11-28
ATE57095T1 (de)	1990-10-15
EP0166183A2 (fr)	1986-01-02
DE3579955D1 (de)	1990-11-08
EP0166183B1 (fr)	1990-10-03
US4711893A (en)	1987-12-08
EP0166183A3 (en)	1987-12-23
JPS60258117A (ja)	1985-12-20

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