ZA858416B - A therapeutically useful compound - Google Patents

A therapeutically useful compound

Info

Publication number: ZA858416B
Authority: ZA; South Africa
Prior art keywords: therapeutically useful; useful compound; imidazole; benzyl; dimethyl
Prior art date: 1984-12-04

Application number

ZA858416A

Other languages

English (en)

Inventor

Raimo Einari Virtanen

Arto Johannes Karjalainen

Kauko Oiva Antero Kurkela

Antti Tapani Vaehae-Vahe

Outi Maritta Vainio-Kivinen

Original Assignee

Farmos Oy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-12-04

Filing date

1985-11-01

Publication date

1986-07-30

1985-11-01 Application filed by Farmos Oy filed Critical Farmos Oy

1986-07-30 Publication of ZA858416B publication Critical patent/ZA858416B/xx

Links

150000001875 compounds Chemical class 0.000 title 1
241000124008 Mammalia Species 0.000 abstract 1
239000000730 antalgic agent Substances 0.000 abstract 1
CUHVIMMYOGQXCV-UHFFFAOYSA-N medetomidine Chemical compound C=1C=CC(C)=C(C)C=1C(C)C1=CNC=N1 CUHVIMMYOGQXCV-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives

Landscapes

Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
Photoreceptors In Electrophotography (AREA)
Stringed Musical Instruments (AREA)

ZA858416A 1984-12-04 1985-11-01 A therapeutically useful compound ZA858416B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FI844786A FI844786A0 (fi)	1984-12-04	1984-12-04	Terapeutiskt utnyttjbar foerening.

Publications (1)

Publication Number	Publication Date
ZA858416B true ZA858416B (en)	1986-07-30

Family

ID=8520010

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA858416A ZA858416B (en)	1984-12-04	1985-11-01	A therapeutically useful compound

Country Status (11)

Country	Link
US (1)	US4670455A (cs)
EP (1)	EP0187471B1 (cs)
JP (1)	JPS61134314A (cs)
AT (1)	ATE65694T1 (cs)
AU (1)	AU572364B2 (cs)
DE (1)	DE3583670D1 (cs)
DK (1)	DK163960C (cs)
FI (1)	FI844786A0 (cs)
IE (1)	IE58269B1 (cs)
NZ (1)	NZ213604A (cs)
ZA (1)	ZA858416B (cs)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI864570A0 (fi) *	1986-11-11	1986-11-11	Farmos Oy	Terapeutiskt anvaendbar foerening.
GB2206880B (en)	1987-07-16	1991-04-24	Farmos Oy	Optical isomers of an imidazole derivative
US5344840A (en) *	1988-02-29	1994-09-06	Orion-Yhtyma Oy	4-substituted imidazole derivatives useful in perioperative care
GB2215206B (en) *	1988-02-29	1991-07-03	Farmos Oy	4-substituted imidazole derivatives useful in perioperative care
US5124157A (en)	1989-08-18	1992-06-23	Cygnus Therapeutic Systems	Method and device for administering dexmedetomidine transdermally
AR015744A1 (es) *	1998-04-01	2001-05-16	Orion Corp	Uso de dexmedetomidina para sedacion en terapia intensiva
FI20041425A0 (fi) *	2004-11-05	2004-11-05	Orion Corp	Transmukosaalinen veterinäärinen koostumus
US7795263B2 (en) *	2008-07-08	2010-09-14	Wildlife Laboratories, Inc.	Pharmaceutical combination for and method of anesthetizing and immobilizing non-domesticated mammals
US20100196286A1 (en) *	2008-12-01	2010-08-05	Armer Thomas A	Inhalation delivery methods and devices
WO2010074753A1 (en)	2008-12-23	2010-07-01	Map Pharmaceuticals, Inc.	Inhalation devices and related methods for administration of sedative hypnotic compounds
US20130096170A1 (en)	2011-10-14	2013-04-18	Hospira, Inc.	Methods of treating pediatric patients using dexmedetomidine
WO2013069025A1 (en)	2011-11-11	2013-05-16	Neon Laboratories Ltd.	"process for the preparation of dexmedetomidine"
US8242158B1 (en)	2012-01-04	2012-08-14	Hospira, Inc.	Dexmedetomidine premix formulation
TWI709417B (zh)	2013-10-07	2020-11-11	美商帝國製藥美國股份有限公司	使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
RU2648449C2 (ru)	2013-10-07	2018-03-26	ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК.	Способы и композиции для трансдермальной доставки неседативного количества дексмедетомидина
RU2018105761A (ru)	2013-10-07	2019-02-26	ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК.	Устройства для трансдермальной доставки дексмедетомидина и способы их применения
US9717796B1 (en)	2016-04-20	2017-08-01	Slypharma, Llc	Heat sterilizeable, premixed, ready to use dexmedetomidine solution packaged in a flexible plastic container
KR20210113439A (ko)	2016-10-31	2021-09-15	테이코쿠 팔마 유에스에이, 인코포레이티드	덱스메데토미딘 경피 전달 장치를 이용한 통증을 관리하는 방법
SG10202107367SA (en)	2016-12-31	2021-08-30	Bioxcel Therapeutics Inc	Use of sublingual dexmedetomidine for the treatment of agitation
ES3004544T3 (en)	2018-06-27	2025-03-12	Bioxcel Therapeutics Inc	Film formulations containing dexmedetomidine and methods of producing them
US11160791B2 (en)	2018-11-01	2021-11-02	Medefil, Inc.	Dexmedetomidine injection premix formulation in ready to use (RTU) bags
US20240024288A1 (en)	2019-07-19	2024-01-25	Bioxcel Therapeutics, Inc.	Non-sedating dexmedetomidine treatment regimens
US11806334B1 (en)	2023-01-12	2023-11-07	Bioxcel Therapeutics, Inc.	Non-sedating dexmedetomidine treatment regimens

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2092569B (en) *	1981-02-05	1984-09-19	Farmos Oy	Substituted imidazole derivatives and their preparation and use
GB2096987B (en) *	1981-04-22	1984-04-04	Farmos Oy	Substituted imidazole and imidazole derivatives and their preparation and use
GB2101114B (en) *	1981-07-10	1985-05-22	Farmos Group Ltd	Substituted imidazole derivatives and their preparation and use
AU566014B2 (en) *	1982-08-14	1987-10-08	Wellcome Foundation Limited, The	Imidazole derivatives

1984
- 1984-12-04 FI FI844786A patent/FI844786A0/fi not_active Application Discontinuation
1985
- 1985-09-25 NZ NZ213604A patent/NZ213604A/xx unknown
- 1985-11-01 ZA ZA858416A patent/ZA858416B/xx unknown
- 1985-11-05 DK DK508985A patent/DK163960C/da not_active IP Right Cessation
- 1985-11-15 AU AU49971/85A patent/AU572364B2/en not_active Expired
- 1985-12-02 IE IE302485A patent/IE58269B1/en not_active IP Right Cessation
- 1985-12-02 AT AT85308748T patent/ATE65694T1/de not_active IP Right Cessation
- 1985-12-02 DE DE8585308748T patent/DE3583670D1/de not_active Expired - Lifetime
- 1985-12-02 EP EP85308748A patent/EP0187471B1/en not_active Expired - Lifetime
- 1985-12-03 US US06/804,197 patent/US4670455A/en not_active Expired - Lifetime
- 1985-12-03 JP JP60272380A patent/JPS61134314A/ja active Granted

Also Published As

Publication number	Publication date
DE3583670D1 (de)	1991-09-05
DK508985A (da)	1986-06-05
JPH0465050B2 (cs)	1992-10-16
AU4997185A (en)	1986-06-12
IE58269B1 (en)	1993-08-25
JPS61134314A (ja)	1986-06-21
DK163960B (da)	1992-04-27
US4670455A (en)	1987-06-02
DK508985D0 (da)	1985-11-05
FI844786A0 (fi)	1984-12-04
EP0187471B1 (en)	1991-07-31
AU572364B2 (en)	1988-05-05
IE853024L (en)	1986-06-04
NZ213604A (en)	1988-09-29
EP0187471A3 (en)	1988-09-14
DK163960C (da)	1992-09-21
ATE65694T1 (de)	1991-08-15
EP0187471A2 (en)	1986-07-16

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