ZA859797B - Carbapenem compounds,their preparation and use - Google Patents

Carbapenem compounds,their preparation and use

Info

Publication number
ZA859797B
ZA859797B ZA859797A ZA859797A ZA859797B ZA 859797 B ZA859797 B ZA 859797B ZA 859797 A ZA859797 A ZA 859797A ZA 859797 A ZA859797 A ZA 859797A ZA 859797 B ZA859797 B ZA 859797B
Authority
ZA
South Africa
Prior art keywords
sup
preparation
carbapenem compounds
hydrogen
compounds
Prior art date
Application number
ZA859797A
Other languages
English (en)
Inventor
Sugimura Yukio
Hashimoto Toshihiko
Tanaka Teruo
Iino Kimio
Shibata Tomoyuki
Miyadera Tetsuo
Sugawara Schinichi
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of ZA859797B publication Critical patent/ZA859797B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Lubricants (AREA)
  • Steroid Compounds (AREA)
  • Indole Compounds (AREA)
ZA859797A 1984-12-25 1985-12-23 Carbapenem compounds,their preparation and use ZA859797B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP28170084 1984-12-25

Publications (1)

Publication Number Publication Date
ZA859797B true ZA859797B (en) 1986-09-24

Family

ID=17642759

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA859797A ZA859797B (en) 1984-12-25 1985-12-23 Carbapenem compounds,their preparation and use

Country Status (18)

Country Link
US (1) US4740507A (de)
EP (1) EP0186525B1 (de)
JP (1) JPS61275279A (de)
KR (1) KR930005332B1 (de)
CN (1) CN1014246B (de)
AT (1) ATE51624T1 (de)
AU (1) AU575232B2 (de)
CA (1) CA1254562A (de)
DE (1) DE3576957D1 (de)
DK (1) DK169384B1 (de)
ES (2) ES8706148A1 (de)
FI (1) FI81576C (de)
HU (1) HU196071B (de)
IE (1) IE58823B1 (de)
NO (1) NO163957C (de)
NZ (1) NZ214676A (de)
PH (1) PH25391A (de)
ZA (1) ZA859797B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60202886A (ja) * 1984-03-27 1985-10-14 Sankyo Co Ltd 1―置換カルバペネム―3―カルボン酸誘導体
JPS6426580A (en) * 1987-07-21 1989-01-27 Sankyo Co Production of carbapenem derivative
US5102877A (en) * 1989-04-28 1992-04-07 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds
US5286721A (en) * 1990-10-15 1994-02-15 Fujisawa Pharmaceutical Co., Ltd. 1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid compounds
TW209220B (de) * 1991-11-27 1993-07-11 Manyu Seiyaku Kk
GB9202298D0 (en) * 1992-02-04 1992-03-18 Ici Plc Antibiotic compounds
GB9210096D0 (en) * 1992-05-11 1992-06-24 Fujisawa Pharmaceutical Co 1-azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid derivatives and their preparation
JP2696807B2 (ja) * 1992-08-06 1998-01-14 田辺製薬株式会社 カルバペネム誘導体の製法
CZ272099A3 (cs) * 1997-02-07 1999-11-17 Kyoto Pharmaceutical Industries, Ltd. Karbapenémové sloučeniny, jejich použití a jejich meziprodukty
NZ508493A (en) 1998-05-01 2002-06-28 Kyoto Pharma Ind Carbapenem derivatives, utilization thereof and intermediate compounds of the same
BR0209970A (pt) * 2001-05-21 2004-04-06 Kyoto Pharma Ind Composto de carbapenem
GB0400382D0 (en) * 2004-01-09 2004-02-11 Glaxo Group Ltd Novel processes
US7932381B2 (en) * 2005-02-15 2011-04-26 Shionogi & Co., Ltd. Process for producing carbapenem derivative and intermediate crystal therefor

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4383946A (en) * 1980-03-27 1983-05-17 Merck & Co., Inc. Process for the preparation of 1-carbapenems and intermediates via silyl-substituted dithioacetals
US4552873A (en) * 1981-08-19 1985-11-12 Sankyo Company Limited Carbapenem compounds, and compositions containing them
JPS5913757A (ja) * 1982-07-14 1984-01-24 Sankyo Co Ltd 3−メルカプトピロリジン誘導体及びその製法
JPS5916892A (ja) * 1982-07-19 1984-01-28 Sankyo Co Ltd カルバペネム−3−カルボン酸誘導体およびその製法
JPS59205379A (ja) * 1983-05-09 1984-11-20 Sumitomo Chem Co Ltd 新規なβ−ラクタム化合物及びその製造法
CA1283906C (en) * 1983-05-09 1991-05-07 Makoto Sunagawa .beta.-LACTAM COMPOUNDS AND PRODUCTION THEREOF

Also Published As

Publication number Publication date
DE3576957D1 (de) 1990-05-10
CN1014246B (zh) 1991-10-09
DK604485A (da) 1986-06-26
ES8707535A1 (es) 1987-08-01
AU5169985A (en) 1986-07-03
ATE51624T1 (de) 1990-04-15
HUT39182A (en) 1986-08-28
CA1254562A (en) 1989-05-23
ES550403A0 (es) 1987-06-01
DK169384B1 (da) 1994-10-17
ES8706148A1 (es) 1987-06-01
IE853300L (en) 1986-06-25
JPS61275279A (ja) 1986-12-05
PH25391A (en) 1991-06-03
US4740507A (en) 1988-04-26
NO163957B (no) 1990-05-07
AU575232B2 (en) 1988-07-21
CN85109699A (zh) 1986-08-13
IE58823B1 (en) 1993-11-17
NZ214676A (en) 1988-06-30
EP0186525A1 (de) 1986-07-02
EP0186525B1 (de) 1990-04-04
FI81576C (fi) 1990-11-12
FI855128A0 (fi) 1985-12-20
ES557035A0 (es) 1987-08-01
FI855128L (fi) 1986-06-26
HU196071B (en) 1988-09-28
NO163957C (no) 1990-08-15
FI81576B (fi) 1990-07-31
KR930005332B1 (ko) 1993-06-17
NO855241L (no) 1986-06-26
KR860004892A (ko) 1986-07-14
DK604485D0 (da) 1985-12-23

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