ZA87467B - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number: ZA87467B
Authority: ZA; South Africa
Prior art keywords: isoquinoline derivatives; isoquinoline; derivatives
Prior art date: 1986-01-24

Application number

ZA87467A

Other languages

English (en)

Inventor

Giuseppe Giardina

Vittorio Vecchietti

Original Assignee

Zambeletti Spa L

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-01-24

Filing date

1987-01-22

Publication date

1987-11-25

1987-01-22 Application filed by Zambeletti Spa L filed Critical Zambeletti Spa L

1987-11-25 Publication of ZA87467B publication Critical patent/ZA87467B/xx

Links

125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Biomedical Technology (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

ZA87467A 1986-01-24 1987-01-22 Isoquinoline derivatives ZA87467B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB868601796A GB8601796D0 (en)	1986-01-24	1986-01-24	Compounds

Publications (1)

Publication Number	Publication Date
ZA87467B true ZA87467B (en)	1987-11-25

Family

ID=10591914

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA87467A ZA87467B (en)	1986-01-24	1987-01-22	Isoquinoline derivatives

Country Status (10)

Country	Link
US (1)	US4806547A (da)
EP (1)	EP0232989B1 (da)
JP (1)	JPH0780855B2 (da)
AU (1)	AU595281B2 (da)
DE (1)	DE3772218D1 (da)
DK (1)	DK35687A (da)
GB (1)	GB8601796D0 (da)
NZ (1)	NZ219030A (da)
PT (1)	PT84187B (da)
ZA (1)	ZA87467B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0232612B1 (en) *	1985-12-23	1990-04-04	Dr. Lo. Zambeletti S.p.A.	Azacyclic compounds, processes for their preparation, and their use as pharmaceuticals
DE68910999T2 (de) *	1988-02-19	1994-03-24	Smithkline Beecham Farma	1,2,3,4-Tetrahydroisoquinoline, Verfharen zu ihrer Herstellung und ihre Verwendung als Kappa-Rezeptor Agonisten.
KR890012970A (ko) *	1988-02-23	1989-09-20	추후보충	테트라히드로 이소퀴놀린 유도체
EP0330467A1 (en) *	1988-02-23	1989-08-30	Glaxo Group Limited	Heterocyclic compounds
ES2075849T3 (es) *	1988-03-16	1995-10-16	Smithkline Beecham Farma	Derivados heterociclicos.
GB8824291D0 (en) *	1988-10-17	1988-11-23	Zambeletti Spa L	Novel use
GB8824400D0 (en) *	1988-10-18	1988-11-23	Glaxo Group Ltd	Chemical compounds
GB8827479D0 (en) *	1988-11-24	1988-12-29	Zambeletti Spa L	Novel compounds
DE3935371A1 (de) *	1988-12-23	1990-07-05	Merck Patent Gmbh	Stickstoffhaltige ringverbindungen
GB8830219D0 (en) *	1988-12-23	1989-02-22	Zambeletti Spa L	Novel compounds
GB8916395D0 (en) *	1989-07-18	1989-09-06	Zambeletti Spa L	Pharmaceuticals
GB8926560D0 (en) *	1989-11-24	1990-01-17	Zambeletti Spa L	Pharmaceuticals
US5428042A (en) *	1990-04-28	1995-06-27	Dr Lo Zambeletti S.P.A.	1-(2H-1-oxo-3,4-dihydronaphtyl-6-yl)-acetyl-piperidines as kappa agonists
DE4215213A1 (de) *	1992-05-09	1993-11-11	Merck Patent Gmbh	Arylacetamide
US5389638A (en) *	1993-09-10	1995-02-14	Abbott Laboratories	Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
TW436484B (en) *	1996-04-24	2001-05-28	Dev Center Biotechnology	1,2,3,4-tetrahydroisoquinoline derivatives having a nitrogen-containing heterocyclic methyl substituent, the preparation process and pharmaceutical composition thereof
CA2682608A1 (en) *	2007-03-30	2008-10-09	Tioga Pharmaceuticals, Inc.	Kappa-opiate agonists for the treatment of diarrhea-predominant and alternating irritable bowel syndrome

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2361390A1 (de) *	1973-12-10	1975-06-19	Merck Patent Gmbh	Isochinolinderivate und verfahren zu ihrer herstellung
US4232160A (en) *	1978-10-18	1980-11-04	Miles Laboratories, Inc.	Isoquinoline propionamides exhibiting analgesic properties
HU189764B (en) *	1983-10-25	1986-07-28	Richter Gedeon Vegyeszeti Gyar Rt,Hu	Process for preparing 1-(bis (substituted methyl)-methyl)-isoquinoline-derivatives
GB8531615D0 (en) *	1985-12-23	1986-02-05	Zambeletti Spa L	Compounds

1986
- 1986-01-24 GB GB868601796A patent/GB8601796D0/en active Pending
1987
- 1987-01-20 EP EP87300457A patent/EP0232989B1/en not_active Expired - Lifetime
- 1987-01-20 DE DE8787300457T patent/DE3772218D1/de not_active Expired - Fee Related
- 1987-01-22 AU AU67915/87A patent/AU595281B2/en not_active Ceased
- 1987-01-22 US US07/006,068 patent/US4806547A/en not_active Expired - Fee Related
- 1987-01-22 DK DK035687A patent/DK35687A/da unknown
- 1987-01-22 ZA ZA87467A patent/ZA87467B/xx unknown
- 1987-01-22 PT PT84187A patent/PT84187B/pt not_active IP Right Cessation
- 1987-01-22 NZ NZ219030A patent/NZ219030A/xx unknown
- 1987-01-23 JP JP62012621A patent/JPH0780855B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
PT84187B (pt)	1989-09-14
DK35687D0 (da)	1987-01-22
AU6791587A (en)	1987-07-30
GB8601796D0 (en)	1986-02-26
EP0232989A3 (en)	1988-06-22
DK35687A (da)	1987-07-25
EP0232989B1 (en)	1991-08-21
NZ219030A (en)	1990-06-26
JPH0780855B2 (ja)	1995-08-30
AU595281B2 (en)	1990-03-29
EP0232989A2 (en)	1987-08-19
US4806547A (en)	1989-02-21
DE3772218D1 (de)	1991-09-26
JPS62240665A (ja)	1987-10-21
PT84187A (pt)	1987-02-01

Publication	Publication Date	Title
GB8617652D0 (en)	1986-08-28	Acylanilide derivatives
GB2198132B (en)	1990-07-25	1-piperazinylpyrimidine derivatives
GB8629875D0 (en)	1987-01-28	Pyridazodiazepine derivatives
ZA87467B (en)	1987-11-25	Isoquinoline derivatives
GB2185483B (en)	1990-10-24	Pyroglutamide derivatives
EP0247381A3 (en)	1988-11-23	5-flurorouracil derivatives
EP0207500A3 (en)	1988-01-13	Isoquinoline derivatives
EP0269839B1 (en)	1990-09-12	5-acylamino-pyrazole derivatives
GB2198729B (en)	1990-05-02	Azaspirodecane derivatives
AR245109A1 (es)	1993-12-30	Un procedimiento para la preparacion de 5-fenil-5h-indeno/1,2-d/ pirimidina.
EP0246002A3 (en)	1988-10-05	Alkenamide derivatives
GB2195636B (en)	1990-05-30	Isoquinoline derivatives
GB2186575B (en)	1989-11-08	Abietamide derivatives
ZA864015B (en)	1988-01-27	Isoquinoline derivatives
GB2194532B (en)	1991-01-30	Isoquinoline derivatives
GB2189487B (en)	1990-05-23	Ergolene derivatives
ZA873637B (en)	1988-01-27	Isoquinoline derivatives
ZA875592B (en)	1988-08-31	Isoquinoline derivatives
EP0267024A3 (en)	1989-03-15	Hydrofluorene derivatives
IL84609A0 (en)	1988-04-29	Isoquinoline derivatives
ZA878935B (en)	1988-10-26	Isoquinoline derivatives
IE863147L (en)	1987-06-02	Tetrahydroisoquinoline derivatives
EP0244193A3 (en)	1989-01-18	Dihalogen-substituted thiocyanopyrimidine derivatives
IE861943L (en)	1987-01-23	Isoquinoline derivative
IE871348L (en)	1987-11-23	Isoquinoline derivatives