ZA87520B - 8alpha-acylaminoergolines,their production and pharmaceutical compositions containing them - Google Patents

8alpha-acylaminoergolines,their production and pharmaceutical compositions containing them

Info

Publication number
ZA87520B
ZA87520B ZA87520A ZA87520A ZA87520B ZA 87520 B ZA87520 B ZA 87520B ZA 87520 A ZA87520 A ZA 87520A ZA 87520 A ZA87520 A ZA 87520A ZA 87520 B ZA87520 B ZA 87520B
Authority
ZA
South Africa
Prior art keywords
acylaminoergolines
8alpha
production
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA87520A
Other languages
English (en)
Inventor
Rene Ziegler
Peter Neumann
Walter Haefliger
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of ZA87520B publication Critical patent/ZA87520B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
    • C07D457/12—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA87520A 1986-01-24 1987-01-23 8alpha-acylaminoergolines,their production and pharmaceutical compositions containing them ZA87520B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3602058 1986-01-24

Publications (1)

Publication Number Publication Date
ZA87520B true ZA87520B (en) 1988-09-28

Family

ID=6292510

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA87520A ZA87520B (en) 1986-01-24 1987-01-23 8alpha-acylaminoergolines,their production and pharmaceutical compositions containing them

Country Status (18)

Country Link
JP (1) JPS62190184A (da)
KR (1) KR870007175A (da)
AU (1) AU6791487A (da)
BE (1) BE1000039A4 (da)
DK (1) DK35787A (da)
ES (1) ES2003774A6 (da)
FI (1) FI870293A7 (da)
FR (1) FR2595699A1 (da)
GB (1) GB2185743A (da)
GR (1) GR870093B (da)
HU (1) HUT45248A (da)
IL (1) IL81355A0 (da)
IT (1) IT1216783B (da)
LU (1) LU86743A1 (da)
NL (1) NL8700046A (da)
PT (1) PT84184A (da)
SE (1) SE8700250L (da)
ZA (1) ZA87520B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8714767D0 (en) * 1987-06-24 1987-07-29 Erba Farmitalia Egoline derivatives
ATE107647T1 (de) * 1984-04-09 1994-07-15 Schering Ag 2-substituierte ergolin-derivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
DK338789A (da) * 1988-07-15 1990-01-16 Schering Ag 2-substituerede ergolinylurinstofderivater og fremgangsmaade til fremstilling deraf, deres anvendelse som laegemidler samt mellemprodukter til fremstilling deraf
DE3915950A1 (de) * 1989-05-12 1990-11-15 Schering Ag 8(alpha)-acylamino-ergoline, ihre herstellung und verwendung als arzneimittel
EP2723735A4 (en) * 2011-06-23 2015-02-18 Map Pharmaceuticals Inc NOVEL ANALOGUES OF FLUORO-ERGOLINE
AU2012355982A1 (en) * 2011-12-19 2014-07-10 Map Pharmaceuticals, Inc. Novel iso-ergoline derivatives
BR112017015510A2 (pt) * 2015-01-20 2018-01-30 Xoc Pharmaceuticals Inc composto de fórmula estrutural (i), método de tratamento e/ou prevenção, método de agonização do receptor d2 em um indivíduo, método de antagonização do receptor d3 em um indivíduo, método de agonização do receptor 5-ht1d em um indivíduo, método de agonização do receptor 5-ht1a em um indivíduo, método de agonização seletiva do receptor 5-ht1d em vez do receptor 5-ht1b em um indivíduo, método de agonização seletiva do re-ceptor 5-ht2c em vez do receptor 5-ht2a ou 5-ht2b em um indivíduo, método de agonização do receptor 5-ht2c em um indivíduo, método de fornecimento de atividade antagonista funcional no receptor 5-ht2b ou receptor 5-ht7, e, método de fornecimento de atividade antagonista funcional nos receptores adrenérgicos em um indivíduo
CN113149982A (zh) 2015-01-20 2021-07-23 Xoc制药股份有限公司 麦角灵化合物及其用途
JP2020522504A (ja) 2017-06-01 2020-07-30 エックスオーシー ファーマシューティカルズ インコーポレイテッドXoc Pharmaceuticals, Inc 多環式化合物およびそれらの用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1517971A (en) * 1974-07-19 1978-07-19 Sandoz Ltd 8alpha-substituted ergoline i derivatives
CH615929A5 (en) * 1975-06-02 1980-02-29 Sandoz Ag Process for the preparation of novel ergoline compounds
CH664568A5 (de) * 1984-01-12 1988-03-15 Sandoz Ag 8-alpha-acylaminoergoline.

Also Published As

Publication number Publication date
LU86743A1 (fr) 1987-09-03
BE1000039A4 (fr) 1987-12-15
NL8700046A (nl) 1987-08-17
DK35787A (da) 1987-07-25
ES2003774A6 (es) 1988-11-16
KR870007175A (ko) 1987-08-17
FI870293A7 (fi) 1987-07-25
PT84184A (pt) 1987-02-01
SE8700250D0 (sv) 1987-01-22
GR870093B (en) 1987-05-25
DK35787D0 (da) 1987-01-22
FI870293A0 (fi) 1987-01-23
HUT45248A (en) 1988-06-28
IL81355A0 (en) 1987-08-31
FR2595699A1 (fr) 1987-09-18
GB8701274D0 (en) 1987-02-25
GB2185743A (en) 1987-07-29
SE8700250L (sv) 1987-07-25
AU6791487A (en) 1987-07-30
IT8747551A0 (it) 1987-01-22
IT1216783B (it) 1990-03-14
JPS62190184A (ja) 1987-08-20

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