ZA878182B - Enhancement of prazosin - Google Patents

Enhancement of prazosin

Info

Publication number: ZA878182B
Authority: ZA; South Africa
Prior art keywords: enhancement; certain; relates; prazosin; conjunctive
Prior art date: 1986-11-05

Application number

ZA878182A

Other languages

English (en)

Inventor

C. Dage Richard

Original Assignee

Merrell Dow Pharmaceuticals Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-11-05

Filing date

1987-10-30

Publication date

1988-05-02

1987-10-30 Application filed by Merrell Dow Pharmaceuticals Inc. filed Critical Merrell Dow Pharmaceuticals Inc.

1988-05-02 Publication of ZA878182B publication Critical patent/ZA878182B/xx

Links

IENZQIKPVFGBNW-UHFFFAOYSA-N prazosin Chemical compound N=1C(N)=C2C=C(OC)C(OC)=CC2=NC=1N(CC1)CCN1C(=O)C1=CC=CO1 IENZQIKPVFGBNW-UHFFFAOYSA-N 0.000 title 1
229960001289 prazosin Drugs 0.000 title 1
239000000496 cardiotonic agent Substances 0.000 abstract 2
108020004102 alpha-1 Adrenergic Receptor Proteins 0.000 abstract 1
102000015009 alpha1-adrenergic receptor activity proteins Human genes 0.000 abstract 1
239000005557 antagonist Substances 0.000 abstract 1
239000002220 antihypertensive agent Substances 0.000 abstract 1
229940030600 antihypertensive agent Drugs 0.000 abstract 1
230000004531 blood pressure lowering effect Effects 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
230000002195 synergetic effect Effects 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ZA878182A 1986-11-05 1987-10-30 Enhancement of prazosin ZA878182B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US92778586A	1986-11-05	1986-11-05

Publications (1)

Publication Number	Publication Date
ZA878182B true ZA878182B (en)	1988-05-02

Family

ID=25455252

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA878182A ZA878182B (en)	1986-11-05	1987-10-30	Enhancement of prazosin

Country Status (11)

Country	Link
EP (1)	EP0268146B1 (da)
JP (1)	JP2612175B2 (da)
KR (1)	KR950013758B1 (da)
AT (1)	ATE59781T1 (da)
DE (1)	DE3767287D1 (da)
DK (1)	DK167209B1 (da)
ES (1)	ES2036560T3 (da)
GR (1)	GR3001375T3 (da)
IE (1)	IE59905B1 (da)
PH (1)	PH23818A (da)
ZA (1)	ZA878182B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK0996447T3 (da) *	1997-05-19	2006-11-13	Zonagen Inc	Kombinationsbehandling til modulation af det humane seksuelle respons
CA2314993A1 (en) *	1997-12-16	1999-06-24	Pfizer Products Inc.	Combination effective for the treatment of impotence
DE102004011512B4 (de)	2004-03-08	2022-01-13	Boehringer Ingelheim Vetmedica Gmbh	Pharmazeutische Zubereitung enthaltend Pimobendan
EP1579862A1 (en)	2004-03-25	2005-09-28	Boehringer Ingelheim Vetmedica Gmbh	Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
US8980894B2 (en)	2004-03-25	2015-03-17	Boehringer Ingelheim Vetmedica Gmbh	Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1920785A1 (en)	2006-11-07	2008-05-14	Boehringer Ingelheim Vetmedica Gmbh	Liquid preparation comprising a complex of pimobendan and cyclodextrin
HUE060093T2 (hu)	2012-03-15	2023-01-28	Boehringer Ingelheim Vetmedica Gmbh	Gyógyszerészeti tablettakészítmény az állatgyógyászati ágazat számára, eljárás annak elõállítására és annak alkalmazása
US20130274245A1 (en) *	2012-04-11	2013-10-17	Jan BLUMENSTEIN	Composition For Prevention of Vasoactivity in the Treatment of Blood Loss and Anemia
HUE054186T2 (hu)	2013-07-19	2021-08-30	Boehringer Ingelheim Vetmedica Gmbh	Éterezett ciklodextrin-származékokat tartalmazó, tartósított, folyékony, vizes gyógyászati készítmény
ES2883448T3 (es)	2013-12-04	2021-12-07	Boehringer Ingelheim Vetmedica Gmbh	Composiciones farmacéuticas mejoradas de pimobendán
US10537570B2 (en)	2016-04-06	2020-01-21	Boehringer Ingelheim Vetmedica Gmbh	Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4130647A (en) *	1977-07-08	1978-12-19	Pfizer Inc.	Methods for treating congestive heart failure and ischemic heart disease
US4601897A (en) *	1985-11-06	1986-07-22	Pfizer Inc.	Prazosin-pirbuterol combination for bronchodilation

1987
- 1987-10-30 ZA ZA878182A patent/ZA878182B/xx unknown
- 1987-11-04 AT AT87116236T patent/ATE59781T1/de not_active IP Right Cessation
- 1987-11-04 PH PH36022A patent/PH23818A/en unknown
- 1987-11-04 KR KR1019870012354A patent/KR950013758B1/ko not_active Expired - Lifetime
- 1987-11-04 IE IE297587A patent/IE59905B1/en not_active IP Right Cessation
- 1987-11-04 ES ES198787116236T patent/ES2036560T3/es not_active Expired - Lifetime
- 1987-11-04 DE DE8787116236T patent/DE3767287D1/de not_active Expired - Lifetime
- 1987-11-04 DK DK578887A patent/DK167209B1/da not_active IP Right Cessation
- 1987-11-04 EP EP87116236A patent/EP0268146B1/en not_active Expired - Lifetime
- 1987-11-05 JP JP62278440A patent/JP2612175B2/ja not_active Expired - Lifetime
1991
- 1991-01-24 GR GR91400079T patent/GR3001375T3/el unknown

Also Published As

Publication number	Publication date
JPS63132837A (ja)	1988-06-04
PH23818A (en)	1989-11-23
JP2612175B2 (ja)	1997-05-21
KR950013758B1 (ko)	1995-11-15
ATE59781T1 (de)	1991-01-15
ES2036560T3 (es)	1993-06-01
DE3767287D1 (de)	1991-02-14
DK167209B1 (da)	1993-09-20
EP0268146A1 (en)	1988-05-25
DK578887A (da)	1988-05-06
DK578887D0 (da)	1987-11-04
EP0268146B1 (en)	1991-01-09
IE872975L (en)	1988-05-05
IE59905B1 (en)	1994-04-20
GR3001375T3 (en)	1992-09-11
KR880005934A (ko)	1988-07-21

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