|
DE3739690A1
(de)
*
|
1987-11-24 |
1989-06-08 |
Hoechst Ag |
Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen
|
|
IL88502A
(en)
*
|
1987-12-14 |
1993-04-04 |
Squibb & Sons Inc |
Pharmaceutical compositions containing an angiotensin converting enzyme inhibitor
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
HU222489B1
(hu)
*
|
1990-07-25 |
2003-07-28 |
Novartis Ag. |
Stabilizált gyógyszerkészítmények és eljárás az előállításukra
|
|
US6300362B1
(en)
|
1990-07-25 |
2001-10-09 |
Novartis Ag (Formerly Sandoz Ltd.) |
Stabilized pharmaceutical compositions comprising acid donors
|
|
US5292520A
(en)
*
|
1990-09-13 |
1994-03-08 |
Akzo N.V. |
Stabilized solid pharmaceutical composition containing acid addition salts of a basic drug and an alkaline stabilizer
|
|
ATE112491T1
(de)
|
1990-09-13 |
1994-10-15 |
Akzo Nobel Nv |
Stabilisierte feste chemische zusammensetzungen.
|
|
US5238935A
(en)
*
|
1991-05-20 |
1993-08-24 |
Schering Corporation |
N-acyl-tetrahydroisoquinolines as inhibitors of acyl-coenzyme A: cholesterol acyl transferase
|
|
US5124337A
(en)
*
|
1991-05-20 |
1992-06-23 |
Schering Corporation |
N-acyl-tetrahydroisoquinolines as inhibitors of acyl-coenzyme a:cholesterol acyl transferase
|
|
FR2665834B1
(fr)
*
|
1991-07-24 |
2001-02-23 |
Sandoz Sa |
Composition pharmaceutique stabilisee par un donneur d'acide chlorhydrique, et sa preparation.
|
|
TW284688B
(da)
*
|
1991-11-20 |
1996-09-01 |
Takeda Pharm Industry Co Ltd |
|
|
SI9111842A
(sl)
*
|
1991-11-25 |
1998-04-30 |
Krka |
Stabilna formulacija soli enalaprila, postopek za njeno pripravo in njena uporaba
|
|
TW483763B
(en)
*
|
1994-09-02 |
2002-04-21 |
Astra Ab |
Pharmaceutical composition comprising of ramipril and dihydropyridine compound
|
|
US5573780A
(en)
*
|
1995-08-04 |
1996-11-12 |
Apotex Usa Inc. |
Stable solid formulation of enalapril salt and process for preparation thereof
|
|
US6296871B1
(en)
|
1998-04-12 |
2001-10-02 |
Ranbaxy Laboratories Limited |
Stable solid pharmaceutical compositions containing enalapril maleate
|
|
ES2242398T3
(es)
|
1998-06-05 |
2005-11-01 |
Warner-Lambert Company Llc |
Estabilizacion de composiciones que contienen inhibidores de la enzima de conversion de la angiotensina utilizando oxido de magnesio.
|
|
US6153223A
(en)
*
|
1998-06-05 |
2000-11-28 |
Watson Pharmaceuticals, Inc. |
Stabilized pharmaceutical compositions
|
|
US20030027837A1
(en)
*
|
1998-12-08 |
2003-02-06 |
Sherman Bernard Charles |
Pharmaceutical compositions comprising quinapril magnesium
|
|
NZ333206A
(en)
*
|
1998-12-08 |
2000-07-28 |
Bernard Charles Sherman |
Solid pharmaceutical compositions comprising a stable magnesium salt of quinapril that acts as a ACE (Angiotensin Converting Enzyme) inhibitor
|
|
US6637359B1
(en)
*
|
1998-12-15 |
2003-10-28 |
Maritrans Inc. |
System and method for internally fitting a new inner hull to an existing outer hull to form a rebuilt double hull vessel
|
|
US6060461A
(en)
*
|
1999-02-08 |
2000-05-09 |
Drake; James Franklin |
Topically applied clotting material
|
|
MY121470A
(en)
*
|
1999-05-03 |
2006-01-28 |
Ranbaxy Lab Ltd |
Stable solid pharmaceutical compositions containing enalapril maleate
|
|
SE9903028D0
(sv)
*
|
1999-08-27 |
1999-08-27 |
Astra Ab |
New use
|
|
PL353199A1
(en)
*
|
1999-08-30 |
2003-11-03 |
Aventis Pharma Deutschland Gmbh |
Use of inhibitors of the renin-angiotensin system in the prevention of cardiovascular events
|
|
US6764694B1
(en)
*
|
1999-08-31 |
2004-07-20 |
Mutual Pharmaceutical Co., Inc. |
Stable formulations of ACE inhibitors, and methods for preparation thereof
|
|
US20030225124A1
(en)
*
|
1999-08-31 |
2003-12-04 |
Spiridon Spireas |
Stable formulations of ACE inhibitors, and methods for preparation thereof
|
|
US20040157911A1
(en)
*
|
1999-08-31 |
2004-08-12 |
Spiridon Spireas |
Storage-stable and bio-stable formulations of ace inhibitors, and methods for preparation thereof
|
|
US6555551B1
(en)
|
1999-08-31 |
2003-04-29 |
Mutual Pharmaceutical Co., Inc. |
Stable formulations of ACE inhibitors, and methods for preparation thereof
|
|
GB0001621D0
(en)
|
2000-01-26 |
2000-03-15 |
Astrazeneca Ab |
Pharmaceutical compositions
|
|
CA2303481A1
(en)
*
|
2000-04-05 |
2001-10-05 |
Bernard Charles Sherman |
Pharmaceutical compositions comprising moexipril magnesium
|
|
US6333332B1
(en)
*
|
2000-08-25 |
2001-12-25 |
Impax Laboratories, Inc. |
Stabilized pharmaceutical compositions containing bupropion hydrochloride
|
|
TWI232102B
(en)
*
|
2001-07-17 |
2005-05-11 |
Shionogi & Co |
A pharmaceutical formulation for injection
|
|
US20040170689A1
(en)
*
|
2001-11-09 |
2004-09-02 |
Odink Debra Alida |
Stabilized formulations comprising hydrolytically unstable compositions
|
|
EA007981B1
(ru)
*
|
2002-01-15 |
2007-02-27 |
Актавис Груп Хф. |
Фармацевтический состав, содержащий хинаприл или фармацевтически приемлемую его соль
|
|
US20050202081A1
(en)
*
|
2002-01-15 |
2005-09-15 |
Deepak Bahl |
Stable pharmaceutical compositions comprising ace inhibitor(s)
|
|
US20030157165A1
(en)
*
|
2002-02-01 |
2003-08-21 |
Sherman Bernard Charles |
Stable saccharide-free tablets comprising a salt of quinapril or moexipril
|
|
US20030215526A1
(en)
*
|
2002-03-08 |
2003-11-20 |
Scott Stofik |
Stable formulations of angiotensin converting enzyme (ACE) inhibitors
|
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
|
ES2322854T3
(es)
*
|
2003-06-26 |
2009-06-30 |
Teva Pharmaceutical Industries Limited |
Composiciones farmaceuticas estables de derivados del acido 2-aza-biciclo(3.3.0)-octano-3-carboxilico.
|
|
US6869963B2
(en)
*
|
2003-07-11 |
2005-03-22 |
Sandoz Ag |
Stable pharmaceutical compositions containing an ACE inhibitor
|
|
AU2003270245A1
(en)
*
|
2003-09-23 |
2005-04-11 |
Texcontor Etablissement |
Stable quinapril compositions
|
|
US20050181055A1
(en)
*
|
2003-10-08 |
2005-08-18 |
Mathur Rajeev S. |
Pharmaceutical compositions of quinapril
|
|
EP1694308A1
(en)
*
|
2003-10-30 |
2006-08-30 |
Lupin Ltd. |
Stable formulations of ace inhibitors and methods for preparation thereof
|
|
GB2411355B
(en)
|
2004-02-27 |
2006-02-22 |
Niche Generics Ltd |
Pharmaceutical composition
|
|
EP1734931A2
(en)
*
|
2004-03-24 |
2006-12-27 |
Actavis Group |
Formulations of ramipril
|
|
LT1729739T
(lt)
*
|
2004-03-29 |
2016-11-10 |
Les Laboratoires Servier |
Kietos farmacinės kompozicijos gamybos būdas
|
|
SI21800A
(sl)
|
2004-05-14 |
2005-12-31 |
Krka, Tovarna Zdravil, D.D., Novo Mesto |
Nov postopek sinteze perindoprila
|
|
DE102004054054A1
(de)
|
2004-11-05 |
2006-05-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
|
|
JP2008024592A
(ja)
*
|
2005-01-28 |
2008-02-07 |
Taisho Pharmaceut Co Ltd |
シアノピロリジン誘導体含有固形製剤用組成物、それを含有する固形製剤及びその製造方法
|
|
GR1006875B
(el)
*
|
2005-06-30 |
2010-07-12 |
"Φαρματεν" Φαρμακευτικη Βιομηχανικη Εμπορικη Α.Ε., |
Βελτιωμενες φαρμακευτικες συνθεσεις περιεχουσες αναστολεις του μετατρεπτικου ενζυμου αγγειοτενσινης και μεθοδοι παρασκευης αυτων.
|
|
GB0518129D0
(en)
*
|
2005-09-06 |
2005-10-12 |
Arrow Int Ltd |
Ramipril formulation
|
|
GB2431579A
(en)
*
|
2005-10-28 |
2007-05-02 |
Arrow Int Ltd |
Ramipril formulations
|
|
US20070098782A1
(en)
*
|
2005-10-28 |
2007-05-03 |
Selamine Limited |
Ramipril Formulation
|
|
RU2429878C2
(ru)
|
2005-11-17 |
2011-09-27 |
Силверстоун Фарма Ист |
Стабильная композиция аморфных солей периндоприла, способ ее получения, в частности промышленного получения, и ее применение в терапии гипертензии
|
|
EP1815857A1
(en)
|
2006-02-02 |
2007-08-08 |
LEK Pharmaceuticals D.D. |
A pharmaceutical composition comprising perindopril
|
|
US20070232680A1
(en)
*
|
2006-04-04 |
2007-10-04 |
Vijayabhaskar Bolugoddu |
Preparation of ramipril and stable pharmaceutical compositions
|
|
US7943655B2
(en)
*
|
2006-04-05 |
2011-05-17 |
Universitat Zurich |
Polymorphic and pseudopolymorphic forms of trandolaprilat, pharmaceutical compositions and methods for production and use
|
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
|
KR101452915B1
(ko)
|
2006-05-04 |
2014-10-21 |
베링거 인겔하임 인터내셔날 게엠베하 |
다형태
|
|
EP1852108A1
(en)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
DPP IV inhibitor formulations
|
|
AU2007264414A1
(en)
*
|
2006-06-30 |
2008-01-03 |
Alphapharm Pty Ltd |
A stabilised composition comprising ACE inhibitors
|
|
GB0624090D0
(en)
*
|
2006-12-01 |
2007-01-10 |
Selamine Ltd |
Ramipril amine salts
|
|
GB0624084D0
(en)
*
|
2006-12-01 |
2007-01-10 |
Selamine Ltd |
Ramipril amino acid salts
|
|
GB0624087D0
(en)
*
|
2006-12-01 |
2007-01-10 |
Selamine Ltd |
Ramipril combination salt
|
|
BRPI0815405A2
(pt)
*
|
2007-08-17 |
2015-02-03 |
Boehringer Ingelheim Int |
Compostos derivados de purina, processo para a preparação de uma composição farmacêutica e uso dos mesmos
|
|
JP2009084242A
(ja)
*
|
2007-10-02 |
2009-04-23 |
Nichi-Iko Pharmaceutical Co Ltd |
安定性に優れた塩酸テモカプリル錠剤
|
|
JP5113476B2
(ja)
*
|
2007-10-09 |
2013-01-09 |
沢井製薬株式会社 |
保存安定性に優れた塩酸テモカプリルの錠剤
|
|
CA2705097A1
(en)
*
|
2007-11-07 |
2009-05-14 |
Janssen Pharmaceutica N.V. |
Combination therapy comprising angiotensin converting enzyme inhibitors and vasopressin receptor antagonists
|
|
WO2009113081A1
(en)
*
|
2008-03-10 |
2009-09-17 |
Lupin Limited |
Tris (hydroxymethyl ) amino methane salt of quinapril and ramipril
|
|
PE20091730A1
(es)
|
2008-04-03 |
2009-12-10 |
Boehringer Ingelheim Int |
Formulaciones que comprenden un inhibidor de dpp4
|
|
PE20100156A1
(es)
*
|
2008-06-03 |
2010-02-23 |
Boehringer Ingelheim Int |
Tratamiento de nafld
|
|
UY32030A
(es)
|
2008-08-06 |
2010-03-26 |
Boehringer Ingelheim Int |
"tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
|
|
KR20190016601A
(ko)
|
2008-08-06 |
2019-02-18 |
베링거 인겔하임 인터내셔날 게엠베하 |
메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
|
|
UA119131C2
(uk)
*
|
2008-08-15 |
2019-05-10 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
Похідні пурину для застосування при лікуванні пов'язаних із fab захворювань
|
|
US20200155558A1
(en)
|
2018-11-20 |
2020-05-21 |
Boehringer Ingelheim International Gmbh |
Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
|
|
JP2012512848A
(ja)
|
2008-12-23 |
2012-06-07 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
有機化合物の塩の形態
|
|
TW201036975A
(en)
|
2009-01-07 |
2010-10-16 |
Boehringer Ingelheim Int |
Treatment for diabetes in patients with inadequate glycemic control despite metformin therapy
|
|
TR200906322A2
(tr)
|
2009-08-17 |
2011-07-21 |
Bi̇lgi̇ç Mahmut |
Çözünürlük ve stabilite özellikleri geliştirilmiş granüller.
|
|
DK2468281T3
(da)
|
2009-08-19 |
2016-03-21 |
Eisai R&D Man Co Ltd |
Quinolinderivatholdig farmaceutisk sammensætning
|
|
ES2364011B1
(es)
|
2009-11-20 |
2013-01-24 |
Gp Pharm, S.A. |
Cápsulas de principios activos farmacéuticos y ésteres de ácidos grasos poliinsaturados para el tratamiento de enfermedades cardiovasculares.
|
|
KR20240090632A
(ko)
|
2009-11-27 |
2024-06-21 |
베링거 인겔하임 인터내셔날 게엠베하 |
리나글립틴과 같은 dpp-iv 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료
|
|
CA3070513C
(en)
|
2010-05-05 |
2023-01-03 |
Boehringer Ingelheim International Gmbh |
A dpp-4 inhibitor for use in treatment of skin-alterations or necrosis
|
|
EP2585051B2
(en)
*
|
2010-06-23 |
2020-04-08 |
KRKA, tovarna zdravil, d.d., Novo mesto |
Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts
|
|
KR20130093012A
(ko)
|
2010-06-24 |
2013-08-21 |
베링거 인겔하임 인터내셔날 게엠베하 |
당뇨병 요법
|
|
AR083878A1
(es)
|
2010-11-15 |
2013-03-27 |
Boehringer Ingelheim Int |
Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
|
|
WO2012085249A2
(en)
|
2010-12-24 |
2012-06-28 |
Krka, D.D., Novo Mesto |
Homogenous pharmaceutical oral dosage forms comprising lercanidipine and enalapril or their pharmaceutically acceptable salts
|
|
JP6038128B2
(ja)
|
2011-06-03 |
2016-12-07 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
レンバチニブ化合物に対する甲状腺癌対象及び腎臓癌対象の反応性を予測及び評価するためのバイオマーカー
|
|
DK2731947T3
(da)
|
2011-07-15 |
2019-04-23 |
Boehringer Ingelheim Int |
Substitueret dimerisk quinazolin-derivat, fremstilling og andvendelse deraf i farmaceutiske sammensætninger til behandling af type i- og type ii-diabetes
|
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
|
WO2013171166A1
(en)
|
2012-05-14 |
2013-11-21 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp-4 inhibitor for use in the treatment of sirs and/or sepsis
|
|
WO2013171167A1
(en)
|
2012-05-14 |
2013-11-21 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in the treatment of podocytes related disorders and/or nephrotic syndrome
|
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
|
US8568747B1
(en)
|
2012-10-05 |
2013-10-29 |
Silvergate Pharmaceuticals, Inc. |
Enalapril compositions
|
|
PL227900B1
(pl)
|
2012-11-15 |
2018-01-31 |
Adamed Spolka Z Ograniczona Odpowiedzialnoscia |
Kompozycja farmaceutyczna zawierająca inhibitor ACE i bloker kanałów wapniowych, sposób jej wytwarzania i jednostka dawkowania zawierająca tę kompozycję
|
|
EP3038465B1
(en)
|
2013-08-30 |
2021-10-06 |
Merck Sharp & Dohme Corp. |
Oral pharmaceutical formulation of omarigliptin
|
|
EP3110449B1
(en)
|
2014-02-28 |
2023-06-28 |
Boehringer Ingelheim International GmbH |
Medical use of a dpp-4 inhibitor
|
|
WO2016015798A1
(en)
|
2014-07-31 |
2016-02-04 |
Pharmathen S.A. |
Orodispersible film composition comprising enalapril for the treatment of hypertension in a pediatric population
|
|
PT3524595T
(pt)
|
2014-08-28 |
2022-09-19 |
Eisai R&D Man Co Ltd |
Derivado de quinolina altamente puro e método para produção do mesmo
|
|
AU2016224583B2
(en)
|
2015-02-25 |
2021-06-03 |
Eisai R&D Management Co., Ltd. |
Method for suppressing bitterness of quinoline derivative
|
|
KR102662228B1
(ko)
|
2015-03-04 |
2024-05-02 |
머크 샤프 앤드 돔 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합
|
|
BR112017027227B1
(pt)
|
2015-06-16 |
2023-12-12 |
Eisai R&D Management Co., Ltd |
Agente anti-câncer
|
|
JP6553726B2
(ja)
|
2015-08-20 |
2019-07-31 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
腫瘍治療剤
|
|
US9463183B1
(en)
|
2015-10-30 |
2016-10-11 |
Silvergate Pharmaceuticals, Inc. |
Lisinopril formulations
|
|
WO2017077425A1
(en)
|
2015-11-07 |
2017-05-11 |
Ftf Pharma Private Limited |
Oral solution of ace inhibitors
|
|
US9669008B1
(en)
|
2016-03-18 |
2017-06-06 |
Silvergate Pharmaceuticals, Inc. |
Enalapril formulations
|
|
EP4233840A3
(en)
|
2016-06-10 |
2023-10-18 |
Boehringer Ingelheim International GmbH |
Combinations of linagliptin and metformin
|
|
JP6581320B2
(ja)
|
2017-02-08 |
2019-09-25 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
腫瘍治療用医薬組成物
|
|
EP3624800A4
(en)
|
2017-05-16 |
2021-02-17 |
Eisai R&D Management Co., Ltd. |
TREATMENT OF HEPATOCELLULAR CARCINOMA
|