ZA886401B - Modified plasminogen activators - Google Patents

Modified plasminogen activators

Info

Publication number
ZA886401B
ZA886401B ZA886401A ZA886401A ZA886401B ZA 886401 B ZA886401 B ZA 886401B ZA 886401 A ZA886401 A ZA 886401A ZA 886401 A ZA886401 A ZA 886401A ZA 886401 B ZA886401 B ZA 886401B
Authority
ZA
South Africa
Prior art keywords
plasminogen activators
modified plasminogen
modified
activators
plasminogen
Prior art date
Application number
ZA886401A
Other languages
English (en)
Inventor
Giovanni Cassani
Cassani Giovanni
Marialuisa Nolli
Nolli Marialuisa
Francesco Blasi
Blasi Francesco
Federico Maria Robbiati
Maria Robbiati Federico
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of ZA886401B publication Critical patent/ZA886401B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6462—Plasminogen activators u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21073—Serine endopeptidases (3.4.21) u-Plasminogen activator (3.4.21.73), i.e. urokinase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
ZA886401A 1987-09-07 1988-08-29 Modified plasminogen activators ZA886401B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878721023A GB8721023D0 (en) 1987-09-07 1987-09-07 Modified plasminogen activators

Publications (1)

Publication Number Publication Date
ZA886401B true ZA886401B (en) 1989-07-26

Family

ID=10623401

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA886401A ZA886401B (en) 1987-09-07 1988-08-29 Modified plasminogen activators

Country Status (14)

Country Link
EP (1) EP0308716A3 (da)
JP (1) JPH01117785A (da)
KR (1) KR890005267A (da)
CN (1) CN1033070A (da)
AU (1) AU2196688A (da)
DK (1) DK491988A (da)
FI (1) FI883943L (da)
GB (1) GB8721023D0 (da)
HU (1) HUT47975A (da)
IL (1) IL87638A (da)
NO (1) NO883963L (da)
NZ (1) NZ226050A (da)
PT (1) PT88436B (da)
ZA (1) ZA886401B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5098840A (en) * 1986-07-03 1992-03-24 The Green Cross Corporation Human prourokinase mutants
AU5515790A (en) * 1989-05-18 1990-11-22 Green Cross Corporation, The Human prourokinase variants, methods of producing same, dna sequences, plasmids and hosts therefor
CA2025181A1 (en) * 1989-10-12 1991-04-13 William G. Weisburg Nucleic acid probes and methods for detecting fungi
JPH0595786A (ja) * 1991-10-07 1993-04-20 Green Cross Corp:The 変異ヒトプロウロキナーゼ
US6120765A (en) * 1993-04-02 2000-09-19 Shiseido Co. Ltd. Urokinase plasminogen activator fragments
JP5408999B2 (ja) 2005-04-19 2014-02-05 アーチャー−ダニエルズ−ミッドランド カンパニー 可溶性低カロリーファイバー組成物およびそれを調製するプロセス
NZ596269A (en) 2006-07-05 2012-12-21 Catalyst Biosciences Inc Protease screening methods and proteases identified thereby
JP2010512324A (ja) 2006-12-08 2010-04-22 アッテヌオン エル エル シー ウロキナーゼ型プラスミノーゲン活性化因子受容体エピトープ、それに由来するモノクローナル抗体及びそれらの使用方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR860875B (en) * 1985-04-04 1986-07-29 Beecham Group Plc Novel compounds
JPH0761266B2 (ja) * 1986-07-03 1995-07-05 株式会社ミドリ十字 変異ヒトプロウロキナ−ゼ
EP0266032A1 (en) * 1986-08-29 1988-05-04 Beecham Group Plc Modified fibrinolytic enzyme
EP0299053A1 (en) * 1987-01-30 1989-01-18 American Home Products Corporation Des-epidermal growth factor plasminogen activators

Also Published As

Publication number Publication date
PT88436B (pt) 1992-11-30
EP0308716A3 (en) 1989-06-14
KR890005267A (ko) 1989-05-13
DK491988A (da) 1989-03-08
PT88436A (pt) 1989-07-31
FI883943A0 (fi) 1988-08-26
NO883963D0 (no) 1988-09-06
NO883963L (no) 1989-03-08
DK491988D0 (da) 1988-09-05
NZ226050A (en) 1991-06-25
IL87638A (en) 1993-04-04
AU2196688A (en) 1989-06-08
HUT47975A (en) 1989-04-28
IL87638A0 (en) 1989-01-31
FI883943A7 (fi) 1989-03-08
JPH01117785A (ja) 1989-05-10
CN1033070A (zh) 1989-05-24
GB8721023D0 (en) 1987-10-14
FI883943L (fi) 1989-03-08
EP0308716A2 (en) 1989-03-29

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