ZA886694B - Anxiolytically active piperazine derivatives - Google Patents

Anxiolytically active piperazine derivatives

Info

Publication number: ZA886694B
Authority: ZA; South Africa
Prior art keywords: piperazine derivatives; active piperazine; anxiolytically; anxiolytically active; properties
Prior art date: 1987-09-11

Application number

ZA886694A

Other languages

English (en)

Inventor

Jan Hartog

Hartog Jan

Johannes Mos

Mos Johannes

Original Assignee

Duphar Int Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-09-11

Filing date

1988-09-08

Publication date

1989-06-28

1988-09-08 Application filed by Duphar Int Res filed Critical Duphar Int Res

1989-06-28 Publication of ZA886694B publication Critical patent/ZA886694B/xx

Links

150000004885 piperazines Chemical class 0.000 title abstract 2
229940066771 systemic antihistamines piperazine derivative Drugs 0.000 title abstract 2
230000000949 anxiolytic effect Effects 0.000 abstract 1
230000036772 blood pressure Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Landscapes

Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Anesthesiology (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Plural Heterocyclic Compounds (AREA)

ZA886694A 1987-09-11 1988-09-08 Anxiolytically active piperazine derivatives ZA886694B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NL8702167		1987-09-11

Publications (1)

Publication Number	Publication Date
ZA886694B true ZA886694B (en)	1989-06-28

Family

ID=19850597

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA886694A ZA886694B (en)	1987-09-11	1988-09-08	Anxiolytically active piperazine derivatives

Country Status (13)

Country	Link
US (1)	US4889852A (da)
EP (1)	EP0307061B1 (da)
JP (1)	JP2749593B2 (da)
AT (1)	ATE135576T1 (da)
AU (1)	AU618279B2 (da)
CA (1)	CA1327163C (da)
DE (1)	DE3855121T2 (da)
DK (1)	DK172628B1 (da)
ES (1)	ES2085852T3 (da)
GR (1)	GR3019544T3 (da)
IE (1)	IE74200B1 (da)
IL (1)	IL87712A (da)
ZA (1)	ZA886694B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE74200B1 (en) *	1987-09-11	1997-07-16	Duphar Int Res	Anxiolytically active piperazine derivatives
US5219855A (en) *	1988-01-29	1993-06-15	Mitsubishi Kasei Corporation	Anxiolytic drug
US4983612A (en) *	1989-10-05	1991-01-08	American Home Products Corporation	Antihypertensive benzopyran derivatives
FR2655988B1 (fr) *	1989-12-20	1994-05-20	Adir Cie	Nouveaux derives de la napht-1-yl piperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5162324A (en) *	1989-12-20	1992-11-10	Adir Et Compagnie	Naphyl piperazines useful as 5-HT1A receptor ligands
EP0605033B1 (en) *	1992-12-21	1999-07-21	Duphar International Research B.V	Enzymatic process for the stereoselective preparation of a hetero-bicyclic alcohol enantiomer
US7504395B2 (en) *	2001-07-20	2009-03-17	Psychogenics, Inc.	Treatment for attention-deficit hyperactivity disorder
US9066903B2 (en)	2006-02-28	2015-06-30	The United States Of America As Represented By The Department Of Veterans Affairs	Pharmacological treatment of Parkinson's disease

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ209876A (en) *	1983-10-17	1988-03-30	Duphar Int Res	Piperazines and pharmaceutical compositions
EP0190472B1 (en) *	1984-12-21	1989-07-12	Duphar International Research B.V	New pharmaceutical compositions having anti-psychotic properties
DE3586794T2 (de) *	1984-12-21	1993-05-27	Duphar Int Res	Arzneimittel mit psychotroper wirkung.
IE74200B1 (en) *	1987-09-11	1997-07-16	Duphar Int Res	Anxiolytically active piperazine derivatives

1988
- 1988-09-07 IE IE269788A patent/IE74200B1/en not_active IP Right Cessation
- 1988-09-07 US US07/241,311 patent/US4889852A/en not_active Expired - Lifetime
- 1988-09-07 DK DK198804972A patent/DK172628B1/da not_active IP Right Cessation
- 1988-09-08 ZA ZA886694A patent/ZA886694B/xx unknown
- 1988-09-08 IL IL87712A patent/IL87712A/xx not_active IP Right Cessation
- 1988-09-08 JP JP63223643A patent/JP2749593B2/ja not_active Expired - Lifetime
- 1988-09-08 CA CA000576743A patent/CA1327163C/en not_active Expired - Fee Related
- 1988-09-09 AU AU22076/88A patent/AU618279B2/en not_active Ceased
- 1988-09-09 EP EP88201970A patent/EP0307061B1/en not_active Expired - Lifetime
- 1988-09-09 ES ES88201970T patent/ES2085852T3/es not_active Expired - Lifetime
- 1988-09-09 DE DE3855121T patent/DE3855121T2/de not_active Expired - Fee Related
- 1988-09-09 AT AT88201970T patent/ATE135576T1/de not_active IP Right Cessation
1996
- 1996-04-03 GR GR960400935T patent/GR3019544T3/el unknown

Also Published As

Publication number	Publication date
DK497288A (da)	1989-03-12
IE882697L (en)	1989-03-11
IL87712A (en)	1992-12-01
ES2085852T3 (es)	1996-06-16
IE74200B1 (en)	1997-07-16
EP0307061B1 (en)	1996-03-20
AU618279B2 (en)	1991-12-19
DE3855121D1 (de)	1996-04-25
IL87712A0 (en)	1989-02-28
CA1327163C (en)	1994-02-22
ATE135576T1 (de)	1996-04-15
GR3019544T3 (en)	1996-07-31
JP2749593B2 (ja)	1998-05-13
JPH01100169A (ja)	1989-04-18
US4889852A (en)	1989-12-26
DK172628B1 (da)	1999-08-02
DK497288D0 (da)	1988-09-07
EP0307061A2 (en)	1989-03-15
AU2207688A (en)	1989-05-11
DE3855121T2 (de)	1996-08-22
EP0307061A3 (en)	1991-07-17

Publication	Publication Date	Title
IL76454A (en)	1989-01-31	Diarylacetylene derivatives,their preparation and pharmaceutical compositions containing them
NZ227131A (en)	1991-09-25	Compositions for improving cognitive function by administering 1,2-oxazole derivatives
ZA887399B (en)	1990-05-30	4-aminopyridine derivatives
GR3019544T3 (en)	1996-07-31	Anxiolytically active piperazine derivatives
JPS6419066A (en)	1989-01-23	Dihydropyridineamides
EP0378824A3 (en)	1990-09-19	Use of omega-3-fatty acids as anticachexia agents
KR960004860B1 (en)	1996-04-16	Substituted pyridine-2,4-dicarboxylic acid compounds and the use thereof and medicaments
YU132088A (en)	1990-02-28	4-amino-substituted derivatives of 1,2-dihydronaphtaline
EP0316845A3 (en)	1990-12-05	1,2,3,4-tetrahydro-5-nitropyrimidine derivatives
EP0276151A3 (en)	1988-12-14	Dissolved composition of ûbenzo-1,2,4-thiadiazine¨-1,1-dioxide
GR3006438T3 (da)	1993-06-21
AU2993789A (en)	1989-08-24	Heterocyclic compounds and antiulcer agents
NZ229300A (en)	1991-04-26	Substituted-2-ethenyl-3,4,5,6-tetrahydrothieno (4,3,2-cf)(3)benzazepine derivatives and pharmaceutical compositions
ZA887158B (en)	1989-05-30	Azachromane derivatives
EP0292806A3 (en)	1990-10-17	Substituted vinyl cephalosporins, process for their preparation and their use as medicines
GR3019047T3 (en)	1996-05-31	Heterocyclic-NMDA antagonists.
ES2032838T3 (es)	1993-03-01	Un procedimiento para preparar derivados tetrahidropirido (1,2-a)indol.
EP0127389A3 (en)	1985-08-07	N,n-diethyl-5-methyl-2h-1-benzothiopyrano-(4,3,2-cd)-indazole-2-ethanamine, compositions comprising the same and uses therefor
DE3268605D1 (en)	1986-02-27	3,7a-diazacyclohepta(j,k)fluorene derivatives, their preparation and therapeutical use
ZA885123B (en)	1989-04-26	Pest-combating agents based on derivatives of 2,3-diaminomaleonitrile
PH23637A (en)	1989-09-27	2,1-benzonthiazepine-2,2-dioxide-5-carboxylic acid derivatives
PH25608A (en)	1991-08-08	3-amino-tetrahydro-isoquinoline
GR3005963T3 (da)	1993-06-07
FI882388A0 (fi)	1988-05-20	4-substituerad 10-cyanmetylenpyrrolo /4,3-e/benzoazepin.
ATE42280T1 (de)	1989-05-15	Derivate des bicyclo(3.3.0>oktans und ihre herstellung.