ZA888089B - Tetrahydro-furo and-thieno/2,3-c/piridines - Google Patents

Tetrahydro-furo and-thieno/2,3-c/piridines

Info

Publication number: ZA888089B
Authority: ZA; South Africa
Prior art keywords: piridines; furo; thieno; tetrahydro
Prior art date: 1987-10-29

Application number

ZA888089A

Other languages

English (en)

Inventor

Albrecht Harreus

Harreus Albrecht

Karl-Heinz Weber

Weber Karl-Heinz

Gerhard Walther

Walther Gerhard

Werner Stransky

Stransky Werner

Franz Josef Kuhn

Josef Kuhn Franz

Guenther Schingnitz

Schingnitz Guenther

Helmut Ensinger

Ensinger Helmut

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1987-10-29

Filing date

1988-10-28

Publication date

1990-07-25

1988-10-28 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

1990-07-25 Publication of ZA888089B publication Critical patent/ZA888089B/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Ophthalmology & Optometry (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Heart & Thoracic Surgery (AREA)
Hospice & Palliative Care (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

ZA888089A 1987-10-29 1988-10-28 Tetrahydro-furo and-thieno/2,3-c/piridines ZA888089B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19873736664 DE3736664A1 (de)	1987-10-29	1987-10-29	Tetrahydro-furo- und -thieno(2,3-c)pyridine, ihre verwendung als arzneimittel und verfahren zu ihrer herstellung

Publications (1)

Publication Number	Publication Date
ZA888089B true ZA888089B (en)	1990-07-25

Family

ID=6339349

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA888089A ZA888089B (en)	1987-10-29	1988-10-28	Tetrahydro-furo and-thieno/2,3-c/piridines

Country Status (17)

Country	Link
EP (1)	EP0314154A3 (cs)
JP (1)	JPH01157983A (cs)
KR (1)	KR890006650A (cs)
AU (1)	AU2443588A (cs)
CS (1)	CS273193B2 (cs)
DD (1)	DD283395A5 (cs)
DE (1)	DE3736664A1 (cs)
DK (1)	DK603588A (cs)
FI (1)	FI884947L (cs)
HU (1)	HU201553B (cs)
IL (1)	IL88184A0 (cs)
NO (1)	NO884835L (cs)
PL (1)	PL275555A1 (cs)
PT (1)	PT88899B (cs)
SU (1)	SU1657064A3 (cs)
YU (1)	YU201288A (cs)
ZA (1)	ZA888089B (cs)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2623810B2 (fr) *	1987-02-17	1992-01-24	Sanofi Sa	Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
US5272148A (en) *	1992-09-09	1993-12-21	Hoechst-Roussel Pharmaceuticals Incorporated	Heteroarenylpiperazines
US8914114B2 (en)	2000-05-23	2014-12-16	The Feinstein Institute For Medical Research	Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
KR20080021152A (ko) *	2000-07-06	2008-03-06	다이이찌 산쿄 가부시키가이샤	히드로피리딘 유도체 산부가염
WO2003072135A2 (en) *	2002-02-26	2003-09-04	North Shore-Long Island Jewish Research Insitute	Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors
US10912712B2 (en)	2004-03-25	2021-02-09	The Feinstein Institutes For Medical Research	Treatment of bleeding by non-invasive stimulation
CA2560756A1 (en)	2004-03-25	2005-10-06	The Feinstein Institute For Medical Research	Methods and devices for reducing bleed time using vagus nerve stimulation
EP2298410B1 (en)	2004-12-27	2013-10-09	The Feinstein Institute for Medical Research	Treating inflammatory disorders by electrical vagus nerve stimulation
US11207518B2 (en)	2004-12-27	2021-12-28	The Feinstein Institutes For Medical Research	Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
TWI392681B (zh) *	2006-04-06	2013-04-11	Daiichi Sankyo Co Ltd	高純度普拉格雷及其酸加成鹽之製法
CN102424686A (zh) *	2007-03-02	2012-04-25	第一三共株式会社	用于制备高纯度普拉格雷盐酸盐的方法
US8391970B2 (en)	2007-08-27	2013-03-05	The Feinstein Institute For Medical Research	Devices and methods for inhibiting granulocyte activation by neural stimulation
US9662490B2 (en)	2008-03-31	2017-05-30	The Feinstein Institute For Medical Research	Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
WO2009146030A1 (en)	2008-03-31	2009-12-03	The Feinstein Institute For Medical Research	Methods and systems for reducing inflammation by neuromodulation of t-cell activity
US8996116B2 (en)	2009-10-30	2015-03-31	Setpoint Medical Corporation	Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
US9211410B2 (en)	2009-05-01	2015-12-15	Setpoint Medical Corporation	Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
CN102573986B (zh)	2009-06-09	2016-01-20	赛博恩特医疗器械公司	用于无导线刺激器的具有袋部的神经封套
US9833621B2 (en)	2011-09-23	2017-12-05	Setpoint Medical Corporation	Modulation of sirtuins by vagus nerve stimulation
WO2014169145A1 (en)	2013-04-10	2014-10-16	Setpoint Medical Corporation	Closed-loop vagus nerve stimulation
EP2515996B1 (en)	2009-12-23	2019-09-18	Setpoint Medical Corporation	Neural stimulation devices and systems for treatment of chronic inflammation
US12172017B2 (en)	2011-05-09	2024-12-24	Setpoint Medical Corporation	Vagus nerve stimulation to treat neurodegenerative disorders
EP2707094B1 (en)	2011-05-09	2016-02-03	Setpoint Medical Corporation	Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US9572983B2 (en)	2012-03-26	2017-02-21	Setpoint Medical Corporation	Devices and methods for modulation of bone erosion
US11311725B2 (en)	2014-10-24	2022-04-26	Setpoint Medical Corporation	Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
WO2016126807A1 (en)	2015-02-03	2016-08-11	Setpoint Medical Corporation	Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US10596367B2 (en)	2016-01-13	2020-03-24	Setpoint Medical Corporation	Systems and methods for establishing a nerve block
WO2017127756A1 (en)	2016-01-20	2017-07-27	Setpoint Medical Corporation	Control of vagal stimulation
EP3405255B1 (en)	2016-01-20	2025-12-31	Setpoint Medical Corporation	IMPLANTABLE MICROSTIMULATORS AND INDUCTION CHARGING SYSTEMS
US11471681B2 (en)	2016-01-20	2022-10-18	Setpoint Medical Corporation	Batteryless implantable microstimulators
US10583304B2 (en)	2016-01-25	2020-03-10	Setpoint Medical Corporation	Implantable neurostimulator having power control and thermal regulation and methods of use
US11173307B2 (en)	2017-08-14	2021-11-16	Setpoint Medical Corporation	Vagus nerve stimulation pre-screening test
US11260229B2 (en)	2018-09-25	2022-03-01	The Feinstein Institutes For Medical Research	Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
WO2020210786A1 (en)	2019-04-12	2020-10-15	Setpoint Medical Corporation	Vagus nerve stimulation to treat neurodegenerative disorders
JP2023512447A (ja)	2020-01-13	2023-03-27	ザファインスタインインスティチューツフォーメディカルリサーチ	脾臓への高密度集束超音波刺激による出血及び出血性疾患の治療
KR20230012585A (ko)	2020-05-21	2023-01-26	더 파인스타인 인스티튜츠 포 메디칼 리서치	미주 신경 자극을 위한 시스템들 및 방법들
US12444497B2 (en)	2021-05-17	2025-10-14	Setpoint Medical Corporation	Neurostimulation parameter authentication and expiration system for neurostimulation
US20250229086A1 (en)	2022-01-20	2025-07-17	Setpoint Medical Corporation	Treatment of inflammatory disorders
US12649059B2 (en)	2022-08-05	2026-06-09	The Feinstein Institutes For Medical Research	Methods for reducing bleeding in hemophilia by vagus nerve stimulation to prime platelets

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2315274A1 (fr) *	1975-06-27	1977-01-21	Parcor	Nouveaux derives de la thieno (2,3-c) pyridine, leur preparation et leurs applications
FR2317303A1 (fr) *	1975-07-09	1977-02-04	Parcor	Procede de preparation de derives de la tetrahydrothieno (3,2-c) et (2,3-c) pyridine

1987
- 1987-10-29 DE DE19873736664 patent/DE3736664A1/de not_active Withdrawn
1988
- 1988-10-27 FI FI884947A patent/FI884947L/fi not_active IP Right Cessation
- 1988-10-27 CS CS712688A patent/CS273193B2/cs unknown
- 1988-10-27 IL IL88184A patent/IL88184A0/xx unknown
- 1988-10-27 YU YU02012/88A patent/YU201288A/xx unknown
- 1988-10-27 DD DD88321141A patent/DD283395A5/de not_active IP Right Cessation
- 1988-10-28 NO NO88884835A patent/NO884835L/no unknown
- 1988-10-28 AU AU24435/88A patent/AU2443588A/en not_active Abandoned
- 1988-10-28 DK DK603588A patent/DK603588A/da not_active Application Discontinuation
- 1988-10-28 SU SU884356747A patent/SU1657064A3/ru active
- 1988-10-28 ZA ZA888089A patent/ZA888089B/xx unknown
- 1988-10-28 PL PL27555588A patent/PL275555A1/xx unknown
- 1988-10-28 PT PT88899A patent/PT88899B/pt not_active IP Right Cessation
- 1988-10-28 KR KR1019880014063A patent/KR890006650A/ko not_active Withdrawn
- 1988-10-28 EP EP19880117961 patent/EP0314154A3/de not_active Withdrawn
- 1988-10-28 HU HU885642A patent/HU201553B/hu not_active IP Right Cessation
- 1988-10-28 JP JP63272853A patent/JPH01157983A/ja active Pending

Also Published As

Publication number	Publication date
KR890006650A (ko)	1989-06-15
FI884947A7 (fi)	1989-04-30
FI884947L (fi)	1989-04-30
SU1657064A3 (ru)	1991-06-15
HU201553B (en)	1990-11-28
CS273193B2 (en)	1991-03-12
PL275555A1 (en)	1989-05-02
EP0314154A2 (de)	1989-05-03
AU2443588A (en)	1989-07-13
YU201288A (en)	1990-08-31
IL88184A0 (en)	1989-06-30
DD283395A5 (de)	1990-10-10
DK603588A (da)	1989-04-30
HUT50824A (en)	1990-03-28
NO884835L (no)	1989-05-02
DK603588D0 (da)	1988-10-28
DE3736664A1 (de)	1989-05-11
NO884835D0 (no)	1988-10-28
EP0314154A3 (de)	1990-12-05
JPH01157983A (ja)	1989-06-21
CS712688A2 (en)	1990-06-13
FI884947A0 (fi)	1988-10-27
PT88899B (pt)	1993-01-29

Publication	Publication Date	Title
GR3001763T3 (en)	1992-11-23	Cycloalkano(1,2-b)indole-sulfonamides
ZA884603B (en)	1989-03-29	2,5-dihydropyrroles
ZA889710B (en)	1989-12-27	4-aralkyl-5-substituted-1,2,4-triazole-5-thiols
KR970009590B1 (en)	1997-06-14	1.2.3.4.-tetrahydro -5-nitropyrimidine derivatives
EP0316843A3 (en)	1990-12-05	1,2,3,4-tetrahydro-5-nitropyrimidine derivatives
EP0217214B1 (en)	1990-05-02	2,4-dioxopyrrolo(2,3-c)pyrroles
IL83679A0 (en)	1988-01-31	2,4,6-trihydroxy-s-triazine derivatives
ZA889251B (en)	1989-08-30	8,9-annelated-beta-carbolines and 8,9-annelated-3,4-dihydro-beta-carbolines
GR3000539T3 (en)	1991-07-31	3,4-dihydro-2h-pyrans
JPS6450861A (en)	1989-02-27	3,5-dialkyl-1-arylpyrazoles
JPS6434951A (en)	1989-02-06	Vermicide based on 2,3-diaminomaleonitrile derivative
CS569987A1 (en)	1988-06-15	Zpusob vyroby 2 naftylamin 6,8 disulfonove kyseliny
CS22787A1 (en)	1988-06-15	Zpusob pripravy 2,6-dialkoxybenzonitrilu
ZA871249B (en)	1987-08-12	Cycloalkano(1,2-b)-indole-sulphonamides
CS689087A1 (en)	1988-07-15	Zpusob vyroby 2,5 dichloranilin 4 sulfonove kyseliny
CS770787A1 (en)	1988-06-15	Sposob pripravy 2,2 dibenzotiazolyldisulfidu
CS569887A1 (en)	1988-06-15	Zpusob izolace 2 naftol 6,8 disulfonove kyseliny
IE871771L (en)	1988-01-07	1,4-piperazines
IE872988L (en)	1988-05-06	2,6-diamino-3-halobenzylpyridines
IE871970L (en)	1988-03-08	2,7-methanobenzoxazonines
CS161787A1 (en)	1988-07-15	N oxidy 2,2,5 trimetyl 3 alkyloxazolidinov
ZA884493B (en)	1989-03-29	2,2-dimethylchroman-3-o 1 derivatives
GB8712993D0 (en)	1987-07-08	1,2-alkylidene-3-phosphoryl-glycerol derivatives
CS438087A1 (en)	1988-06-15	Zpusob pripravy 2 methyl 7,8 oktadecinu
CS553587A1 (en)	1988-06-15	1 2 alkyltio 6 benzotiazolylaminometyl 5 3,4 di chlorfenyl 1,2,3,4 tetrazoly