ZA889452B - Process for preparing bis(3,5-dioxopiperazinyl)alkanes or alkenes - Google Patents

Process for preparing bis(3,5-dioxopiperazinyl)alkanes or alkenes

Info

Publication number: ZA889452B
Authority: ZA; South Africa
Prior art keywords: formula; chr1; chr2; dioxopiperazinyl; alkenes
Prior art date: 1988-02-17

Application number

ZA889452A

Other languages

English (en)

Inventor

Chih-Yun Johnny Tu

Johnny Tu Chih-Yun

George Clark

Clark George

Giampetro Borsotti

Borsotti Giampetro

Original Assignee

Erbamont Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-17

Filing date

1988-12-19

Publication date

1990-05-30

1988-12-19 Application filed by Erbamont Inc filed Critical Erbamont Inc

1990-05-30 Publication of ZA889452B publication Critical patent/ZA889452B/xx

Links

150000001335 aliphatic alkanes Chemical class 0.000 title 1
150000001336 alkenes Chemical class 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 2
239000002253 acid Substances 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical compound N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 abstract 1
239000005977 Ethylene Substances 0.000 abstract 1
KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
230000002378 acidificating effect Effects 0.000 abstract 1
150000001450 anions Chemical class 0.000 abstract 1
150000004985 diamines Chemical class 0.000 abstract 1
229910052739 hydrogen Inorganic materials 0.000 abstract 1
239000001257 hydrogen Substances 0.000 abstract 1
239000002184 metal Substances 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
238000007363 ring formation reaction Methods 0.000 abstract 1
229910021653 sulphate ion Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/06—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members
- C07D241/08—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having one or two double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Hydrogenated Pyridines (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Compositions Of Macromolecular Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA889452A 1988-02-17 1988-12-19 Process for preparing bis(3,5-dioxopiperazinyl)alkanes or alkenes ZA889452B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/157,195 US4963679A (en)	1988-02-17	1988-02-17	Process for preparing bis (3,5-dioxopiperazinyl) alkanes or alkenes

Publications (1)

Publication Number	Publication Date
ZA889452B true ZA889452B (en)	1990-05-30

Family

ID=22562711

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA889452A ZA889452B (en)	1988-02-17	1988-12-19	Process for preparing bis(3,5-dioxopiperazinyl)alkanes or alkenes

Country Status (14)

Country	Link
US (1)	US4963679A (de)
EP (1)	EP0330381B1 (de)
JP (1)	JP2629038B2 (de)
KR (1)	KR970009041B1 (de)
AT (1)	ATE123027T1 (de)
AU (1)	AU611235B2 (de)
CA (1)	CA1303614C (de)
DE (1)	DE68922760T2 (de)
DK (1)	DK174513B1 (de)
ES (1)	ES2072295T3 (de)
FI (1)	FI97294C (de)
HU (1)	HU203326B (de)
NO (1)	NO168821C (de)
ZA (1)	ZA889452B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4764614A (en) *	1987-03-23	1988-08-16	Monsanto Company	Process for preparing (S)(+)-4,4'(methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)
US5744455A (en) *	1988-01-27	1998-04-28	New York University	Reduction of anthracycline-induced cardiotoxicity
AU642519B2 (en) *	1990-07-04	1993-10-21	Zenyaku Kogyo Kabushiki Kaisha	Water-soluble bis-dioxopiperazine derivative
GB9122677D0 (en) *	1991-10-25	1991-12-11	Eurocetus Bv	Process for preparing(s)(+)-4,4'-(1-methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)
TW482806B (en) *	1998-06-02	2002-04-11	Ciba Sc Holding Ag	Compositions stabilized by dioxopiperazinyl derivatives
YU17002A (sh)	1999-09-10	2004-11-25	Cyathus Exquirere Pharmaforschungs Gmbh.	Upotreba deksrazoksana u lečenju psorijaze
CA2384685A1 (en) *	1999-09-10	2001-03-22	Cyathus Exquirere Pharmaforschungs Gmbh	Use dexrazoxane for treating psoriasis
AT504621B1 (de)	2006-11-24	2014-08-15	Cyathus Exquirere Pharmaforschungsgmbh	Neues verfahren zur herstellung von 4,4'-(1-methyl -1,2-ethandiyl)-bis-(2,6-piperazindion)
CN100564363C (zh) *	2007-10-17	2009-12-02	江苏奥赛康药业有限公司	一种精制右丙亚胺的方法
CN101684100B (zh) *	2008-09-26	2011-11-16	重庆海腾制药有限公司	得拉唑沙或其可药用盐的制备方法
WO2012081036A2 (en) *	2010-12-13	2012-06-21	Sequent Scientific Limited	A process for preparation of 4,4'-(1-methyl-1,2-ethandiyl)-bis-(2,6-piperazinedione)
CN110804022B (zh) *	2019-11-06	2023-01-17	扬子江药业集团有限公司	一种右丙亚胺的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2461519A (en) *	1948-03-17	1949-02-15	Frederick C Bersworth	Method of producing carboxylic substituted aliphatic amines and metallic salts thereof
NL273691A (de) *	1961-01-19	1900-01-01
US3941790A (en) *	1967-07-03	1976-03-02	National Research Development Corporation	Bis diketopiperazines
GB1234935A (en) *	1967-07-03	1971-06-09	Nat Res Dev	Piperazine derivatives
GB1374979A (en) *	1970-12-21	1974-11-20	Nat Res Dev	3,5-dioxopiperazine derivatives
GB1236947A (en) *	1968-08-15	1971-06-23	Ici Ltd	Process for the preparation of piperazine derivatives
BE787766A (fr) *	1971-08-21	1973-02-19	Merck Patent Gmbh	Imides d'acide glutarique et leur procede de preparation
US4704465A (en) *	1985-11-22	1987-11-03	Monsanto Company	Process for preparing ethylenediaminetetraacetonitrile
US4764614A (en) *	1987-03-23	1988-08-16	Monsanto Company	Process for preparing (S)(+)-4,4'(methyl-1,2-ethanediyl)-bis(2,6-piperazinedione)

1988
- 1988-02-17 US US07/157,195 patent/US4963679A/en not_active Expired - Lifetime
- 1988-12-06 NO NO885415A patent/NO168821C/no unknown
- 1988-12-06 AU AU26566/88A patent/AU611235B2/en not_active Expired
- 1988-12-09 CA CA000585525A patent/CA1303614C/en not_active Expired - Fee Related
- 1988-12-19 ZA ZA889452A patent/ZA889452B/xx unknown
1989
- 1989-01-20 JP JP1011797A patent/JP2629038B2/ja not_active Expired - Lifetime
- 1989-02-16 FI FI890760A patent/FI97294C/fi not_active IP Right Cessation
- 1989-02-16 DK DK198900721A patent/DK174513B1/da not_active IP Right Cessation
- 1989-02-16 KR KR1019890001768A patent/KR970009041B1/ko not_active Expired - Lifetime
- 1989-02-16 HU HU89783A patent/HU203326B/hu unknown
- 1989-02-17 EP EP89301540A patent/EP0330381B1/de not_active Expired - Lifetime
- 1989-02-17 DE DE68922760T patent/DE68922760T2/de not_active Expired - Lifetime
- 1989-02-17 AT AT89301540T patent/ATE123027T1/de not_active IP Right Cessation
- 1989-02-17 ES ES89301540T patent/ES2072295T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
NO885415D0 (no)	1988-12-06
NO168821B (no)	1991-12-30
NO885415L (no)	1989-08-18
DK72189D0 (da)	1989-02-16
HUT51260A (en)	1990-04-28
DK72189A (da)	1989-08-18
US4963679A (en)	1990-10-16
FI890760A7 (fi)	1989-08-18
KR970009041B1 (ko)	1997-06-03
AU611235B2 (en)	1991-06-06
FI97294C (fi)	1996-11-25
DK174513B1 (da)	2003-05-05
ATE123027T1 (de)	1995-06-15
EP0330381B1 (de)	1995-05-24
FI890760A0 (fi)	1989-02-16
AU2656688A (en)	1989-08-17
FI97294B (fi)	1996-08-15
DE68922760T2 (de)	1995-11-23
ES2072295T3 (es)	1995-07-16
JP2629038B2 (ja)	1997-07-09
NO168821C (no)	1992-04-08
HU203326B (en)	1991-07-29
JPH01228971A (ja)	1989-09-12
EP0330381A1 (de)	1989-08-30
KR890013000A (ko)	1989-09-20
DE68922760D1 (de)	1995-06-29
CA1303614C (en)	1992-06-16

Publication	Publication Date	Title
ZA889452B (en)	1990-05-30	Process for preparing bis(3,5-dioxopiperazinyl)alkanes or alkenes
HU910847D0 (en)	1991-09-30	Process for producing chloro-triazole derivatives
HUT40598A (en)	1987-01-28	Process for production of optically active alpha-arylalcane acids
GR3029836T3 (en)	1999-06-30	Process for producing n-biphenylmethylthiadiazoline derivative or salt thereof and intermediate for producing the same
CA2282381A1 (en)	1998-09-11	Process for the preparation of nicotinic acids
EP0832982A3 (de)	1998-09-02	Verfahren zur Herstellung von Z-L-Asparaginsäure-Dinatriumsalz aus Fumarsäure
SG47670A1 (en)	1998-04-17	Methof for the preparation of 2-perfluoroalkyl-3-ocazolin-5-one
GB8721442D0 (en)	1987-10-21	Process
EP0242706A3 (en)	1989-08-23	Process for preparing alpha-aminoalkylphosphonic acids
DE3777274D1 (de)	1992-04-16	Synthese von azetidinonen.
TW370520B (en)	1999-09-21	A process for the preparation of NG-monomethyl-L-arginine hydrochloride
HUT59371A (en)	1992-05-28	Process for producing aliphatic amides and their salts
PT80563A (en)	1985-06-01	Chemical process
TH23419A (th)	1997-02-10	การทำปฏิกิริยาของวัสดุคาร์บอนกับเกลือไดเอโซเนียมและผลผลิตของคาร์บอนที่ได้รับ
JPS5663945A (en)	1981-05-30	Preparation of novel alkanolamine derivative
TH8283B (th)	1998-08-17	การทำปฏิกิริยาของวัสดุคาร์บอนกับเกลือไดเอโซเนียมและผลผลิตของคาร์บอนที่ได้รับ