ZA89309B - Process for preparing 1-hydroxyalkyl-2-methyl-5-nitroimidazoles - Google Patents

Process for preparing 1-hydroxyalkyl-2-methyl-5-nitroimidazoles

Info

Publication number
ZA89309B
ZA89309B ZA89309A ZA89309A ZA89309B ZA 89309 B ZA89309 B ZA 89309B ZA 89309 A ZA89309 A ZA 89309A ZA 89309 A ZA89309 A ZA 89309A ZA 89309 B ZA89309 B ZA 89309B
Authority
ZA
South Africa
Prior art keywords
formula
nitroimidazoles
hydroxyalkyl
preparing
iii
Prior art date
Application number
ZA89309A
Other languages
English (en)
Inventor
Albert Buforn
Buforn Albert
Viviane Massonneau
Massonneau Viviane
Michel Mulhauser
Mulhauser Michel
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of ZA89309B publication Critical patent/ZA89309B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Cosmetics (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Steroid Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Detergent Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Phenolic Resins Or Amino Resins (AREA)
ZA89309A 1988-01-15 1989-01-13 Process for preparing 1-hydroxyalkyl-2-methyl-5-nitroimidazoles ZA89309B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR888800417A FR2625999B1 (fr) 1988-01-15 1988-01-15 Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles

Publications (1)

Publication Number Publication Date
ZA89309B true ZA89309B (en) 1989-10-25

Family

ID=9362338

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA89309A ZA89309B (en) 1988-01-15 1989-01-13 Process for preparing 1-hydroxyalkyl-2-methyl-5-nitroimidazoles

Country Status (23)

Country Link
US (1) US4925951A (da)
EP (1) EP0325513B1 (da)
JP (1) JPH01216977A (da)
KR (1) KR890011857A (da)
CN (1) CN1023220C (da)
AT (1) ATE87913T1 (da)
AU (1) AU608934B2 (da)
CA (1) CA1310328C (da)
DE (1) DE68905830T2 (da)
DK (1) DK14689A (da)
ES (1) ES2054036T3 (da)
FI (1) FI890188A7 (da)
FR (1) FR2625999B1 (da)
GR (1) GR3007573T3 (da)
HU (1) HU200448B (da)
IE (1) IE890093L (da)
IL (1) IL88946A (da)
MX (1) MX169605B (da)
NO (1) NO171911C (da)
PT (1) PT89445B (da)
SU (1) SU1657059A3 (da)
YU (1) YU7489A (da)
ZA (1) ZA89309B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2625998B1 (fr) * 1988-01-15 1990-06-08 Rhone Poulenc Sante Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles
ES2054035T3 (es) * 1988-01-15 1994-08-01 Rhone Poulenc Sante Procedimiento para la preparacion de alquil-1 nitro-5 imidazoles.
CN100376559C (zh) * 2006-05-22 2008-03-26 浙江苏泊尔制药有限公司 塞克硝唑的制备方法
CN102321028B (zh) * 2011-06-30 2013-12-25 湖北省宏源药业有限公司 一种合成2-甲基-5-硝基咪唑-1-乙醇的方法
KR20170052626A (ko) 2014-09-05 2017-05-12 심바이오믹스 세러퓨틱스 엘엘씨 세균질증 치료에 사용하기 위한 세크니다졸
CA2988082C (en) 2015-06-01 2020-09-29 Symbiomix Therapeutics, Llc Novel nitroimidazole formulations and uses thereof
US12280037B2 (en) 2020-09-22 2025-04-22 Evofem Biosciences, Inc. Method and pharmaceutical composition for treating or preventing trichomoniasis and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1212028A (fr) * 1957-09-20 1960-03-21 Rhone Poulenc Sa Nouveaux dérivés du nitro-5' imidazole et leur préparation
US3178446A (en) * 1961-07-27 1965-04-13 Luso Farmaco Inst Oxyethylation of imidazole compounds
FR3270M (fr) * 1963-10-10 1965-04-26 Rhone Poulenc Sa Nouveaux dérivés de l'imidazole et compositions les contenant.
FR1379787A (fr) * 1963-10-18 1964-11-27 Rhone Poulenc Sa Procédé de préparation de dérivés de l'imidazole
FR1545317A (fr) * 1966-11-26 1968-11-08 Richter Gedeon Vegyeszet Procédé de préparation de dérivés d'imidazoles
GB1277666A (en) * 1969-12-17 1972-06-14 Pfizer Ltd Improvements in the n-alkylation of nitroimidazoles
FR2625998B1 (fr) * 1988-01-15 1990-06-08 Rhone Poulenc Sante Procede de preparation d'hydroxyalkyl-1 methyl-2 nitro-5 imidazoles
ES2054035T3 (es) * 1988-01-15 1994-08-01 Rhone Poulenc Sante Procedimiento para la preparacion de alquil-1 nitro-5 imidazoles.

Also Published As

Publication number Publication date
ES2054036T3 (es) 1994-08-01
EP0325513A1 (fr) 1989-07-26
IL88946A (en) 1993-03-15
CA1310328C (fr) 1992-11-17
AU2845389A (en) 1989-07-20
PT89445A (pt) 1990-02-08
FI890188A0 (fi) 1989-01-13
SU1657059A3 (ru) 1991-06-15
DK14689D0 (da) 1989-01-13
NO890160L (no) 1989-07-17
FR2625999A1 (fr) 1989-07-21
FI890188L (fi) 1989-07-16
KR890011857A (ko) 1989-08-23
CN1023220C (zh) 1993-12-22
NO171911B (no) 1993-02-08
EP0325513B1 (fr) 1993-04-07
DE68905830D1 (de) 1993-05-13
FI890188A7 (fi) 1989-07-16
AU608934B2 (en) 1991-04-18
IL88946A0 (en) 1989-08-15
CN1035289A (zh) 1989-09-06
DK14689A (da) 1989-07-16
FR2625999B1 (fr) 1990-06-08
HUT49587A (en) 1989-10-30
DE68905830T2 (de) 1993-09-23
HU200448B (en) 1990-06-28
YU7489A (en) 1990-12-31
ATE87913T1 (de) 1993-04-15
GR3007573T3 (da) 1993-08-31
JPH01216977A (ja) 1989-08-30
PT89445B (pt) 1993-09-30
NO171911C (no) 1993-05-19
IE890093L (en) 1989-07-15
US4925951A (en) 1990-05-15
MX169605B (es) 1993-07-14
NO890160D0 (no) 1989-01-13

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