ZA896376B - Neuropeptide y agonists - Google Patents

Neuropeptide y agonists

Info

Publication number
ZA896376B
ZA896376B ZA896376A ZA896376A ZA896376B ZA 896376 B ZA896376 B ZA 896376B ZA 896376 A ZA896376 A ZA 896376A ZA 896376 A ZA896376 A ZA 896376A ZA 896376 B ZA896376 B ZA 896376B
Authority
ZA
South Africa
Prior art keywords
neuropeptide
agonists
npy
derivatives
agonism
Prior art date
Application number
ZA896376A
Other languages
English (en)
Inventor
John Leonard Krstenansky
Leonard Krstenansky John
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA896376B publication Critical patent/ZA896376B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57545—Neuropeptide Y
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA896376A 1988-08-26 1989-08-21 Neuropeptide y agonists ZA896376B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23759188A 1988-08-26 1988-08-26

Publications (1)

Publication Number Publication Date
ZA896376B true ZA896376B (en) 1990-05-30

Family

ID=22894367

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA896376A ZA896376B (en) 1988-08-26 1989-08-21 Neuropeptide y agonists

Country Status (17)

Country Link
EP (1) EP0355793B1 (es)
JP (1) JP2791955B2 (es)
KR (1) KR0149160B1 (es)
CN (1) CN1042155A (es)
AT (1) ATE140235T1 (es)
AU (1) AU618118B2 (es)
CA (1) CA1341336C (es)
DE (1) DE68926804T2 (es)
DK (1) DK420789A (es)
ES (1) ES2091757T3 (es)
FI (1) FI894006A7 (es)
HU (1) HU204852B (es)
IL (1) IL91395A0 (es)
NO (1) NO893430L (es)
NZ (1) NZ230384A (es)
PT (1) PT91538B (es)
ZA (1) ZA896376B (es)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69229283T2 (de) * 1991-11-06 1999-09-23 Garvan Institute Of Medical Research, Darlinghurst Humaner neuropeptid y-y1 rezeptor
JPH08501055A (ja) * 1991-12-19 1996-02-06 ガーヴァン インスティチュート オブ メディカル リサーチ 神経ペプチドチロシンの生物学的機能を抑制する新規な分子
AU662032B2 (en) * 1991-12-19 1995-08-17 Garvan Institute Of Medical Research A novel molecule which inhibits neuropeptide tyrosine biological function
GB9213215D0 (en) * 1992-06-20 1992-08-05 Wellcome Found Peptides
CA2165200A1 (en) * 1993-06-18 1995-01-05 Ambikaipakan Balasubramaniam Neuropeptide y antagonists and agonists
US5516653A (en) * 1993-12-28 1996-05-14 Synaptic Pharmaceutical Corporation DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof
US5545549A (en) 1994-02-03 1996-08-13 Synaptic Pharmaceutical Corporation DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof
US5989920A (en) * 1994-12-02 1999-11-23 Synaptic Pharmaceutical Corporation Methods of modifying feeding behavior compounds useful in such methods and DNA encoding a hypothalmic atypical neuropeptide Y/peptide YY receptor Y5
US5602024A (en) 1994-12-02 1997-02-11 Synaptic Pharmaceutical Corporation DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof
AUPN646795A0 (en) 1995-11-09 1995-11-30 Garvan Institute Of Medical Research Neuropeptide Y-Y5 receptor
DE19652033A1 (de) * 1996-12-13 1998-06-18 Irmgard Dr Med Guertner Neuropeptid (CGRP) als Modulator zur Zelldifferenzierung und Proliferation
US6713265B1 (en) 1997-06-04 2004-03-30 Synaptic Pharmaceutical Corporation Methods of modifying feeding behavior, compounds useful in such methods, and DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5)
WO2004098591A2 (en) 2003-05-05 2004-11-18 Probiodrug Ag Inhibitors of glutaminyl cyclase and their use in the treatment of neurological diseases
AU2004290499C1 (en) 2003-11-03 2011-02-24 Probiodrug Ag Combinations useful for the treatment of neuronal disorders
CA2554809C (en) 2004-02-05 2014-04-29 Probiodrug Ag Novel n-alkyl thiourea- and thioamide-substituted imidazolyl inhibitors of glutaminyl cyclase
US8278345B2 (en) 2006-11-09 2012-10-02 Probiodrug Ag Inhibitors of glutaminyl cyclase
ATE554085T1 (de) 2006-11-30 2012-05-15 Probiodrug Ag Neue inhibitoren von glutaminylcyclase
JP5930573B2 (ja) 2007-03-01 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤の新規使用
EP2142514B1 (en) 2007-04-18 2014-12-24 Probiodrug AG Thiourea derivatives as glutaminyl cyclase inhibitors
JP5934645B2 (ja) 2009-09-11 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体
JP6026284B2 (ja) 2010-03-03 2016-11-16 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤
NZ602312A (en) 2010-03-10 2014-02-28 Probiodrug Ag Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5)
WO2011131748A2 (en) 2010-04-21 2011-10-27 Probiodrug Ag Novel inhibitors
EP2686313B1 (en) 2011-03-16 2016-02-03 Probiodrug AG Benzimidazole derivatives as inhibitors of glutaminyl cyclase
ES2812698T3 (es) 2017-09-29 2021-03-18 Probiodrug Ag Inhibidores de glutaminil ciclasa
CN111494606B (zh) * 2020-04-24 2021-12-14 广州医科大学 神经肽y的新应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3811193A1 (de) * 1988-04-01 1989-10-19 Boehringer Ingelheim Kg Neue peptide, verfahren zu ihrer herstellung und diese peptide enthaltende pharmazeutische zusammensetzungen

Also Published As

Publication number Publication date
EP0355793A2 (en) 1990-02-28
EP0355793A3 (en) 1992-04-22
AU4082889A (en) 1990-03-01
JP2791955B2 (ja) 1998-08-27
CA1341336C (en) 2002-01-29
DE68926804D1 (de) 1996-08-14
FI894006A0 (fi) 1989-08-25
AU618118B2 (en) 1991-12-12
CN1042155A (zh) 1990-05-16
NZ230384A (en) 1996-03-26
KR0149160B1 (ko) 1998-10-15
HU204852B (en) 1992-02-28
PT91538B (pt) 1995-05-04
FI894006L (fi) 1990-02-27
NO893430L (no) 1990-02-27
JPH02111794A (ja) 1990-04-24
NO893430D0 (no) 1989-08-25
HUT50849A (en) 1990-03-28
DE68926804T2 (de) 1996-12-12
PT91538A (pt) 1990-03-08
DK420789D0 (da) 1989-08-25
EP0355793B1 (en) 1996-07-10
IL91395A0 (en) 1990-04-29
ES2091757T3 (es) 1996-11-16
FI894006A7 (fi) 1990-02-27
KR900002799A (ko) 1990-03-23
ATE140235T1 (de) 1996-07-15
DK420789A (da) 1990-02-27

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