ZA897618B - Antimalarial compositions and methods of treatment using quinidine,artemisinine and its derivates - Google Patents
Antimalarial compositions and methods of treatment using quinidine,artemisinine and its derivatesInfo
- Publication number
- ZA897618B ZA897618B ZA897618A ZA897618A ZA897618B ZA 897618 B ZA897618 B ZA 897618B ZA 897618 A ZA897618 A ZA 897618A ZA 897618 A ZA897618 A ZA 897618A ZA 897618 B ZA897618 B ZA 897618B
- Authority
- ZA
- South Africa
- Prior art keywords
- artemisinine
- quinidine
- derivates
- treatment
- methods
- Prior art date
Links
- LOUPRKONTZGTKE-LHHVKLHASA-N quinidine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@H]2[C@@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-LHHVKLHASA-N 0.000 title 2
- 230000000078 anti-malarial effect Effects 0.000 title 1
- 239000003430 antimalarial agent Substances 0.000 title 1
- BLUAFEHZUWYNDE-NNWCWBAJSA-N artemisinin Chemical compound C([C@](OO1)(C)O2)C[C@H]3[C@H](C)CC[C@@H]4[C@@]31[C@@H]2OC(=O)[C@@H]4C BLUAFEHZUWYNDE-NNWCWBAJSA-N 0.000 title 1
- 229960004191 artemisinin Drugs 0.000 title 1
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229960001404 quinidine Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP88116605 | 1988-10-07 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA897618B true ZA897618B (en) | 1990-06-27 |
Family
ID=8199431
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA897618A ZA897618B (en) | 1988-10-07 | 1989-10-06 | Antimalarial compositions and methods of treatment using quinidine,artemisinine and its derivates |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0362810B1 (fr) |
| JP (1) | JPH02157223A (fr) |
| KR (1) | KR900005978A (fr) |
| CN (1) | CN1041694A (fr) |
| AU (1) | AU4263789A (fr) |
| DE (1) | DE68906345T2 (fr) |
| ES (1) | ES2054975T3 (fr) |
| MX (1) | MX17877A (fr) |
| NZ (1) | NZ230926A (fr) |
| ZA (1) | ZA897618B (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN166154B (fr) * | 1987-05-08 | 1990-03-24 | Hoechst India | |
| CN1058717A (zh) * | 1990-08-08 | 1992-02-19 | 中国人民解放军军事医学科学院微生物流行病研究所 | 抗疟新药—复方蒿甲醚及其制备方法 |
| US5637594A (en) * | 1991-04-11 | 1997-06-10 | Ciba Geigy Corporation | Antimalarial synergistic compositions containing benflumetol |
| NZ246606A (en) * | 1992-02-07 | 1995-09-26 | Ciba Geigy Ag | Antimalarial compostions containing a synergistic combination of benflumetol and quinine or a derivative thereof |
| CH692321A5 (de) * | 1997-11-03 | 2002-05-15 | Mepha Ag | Pharmazeutisch wirksame Zusammensetzung, welche eine gegen Malariaparasiten wirksame Substanz enthält. |
| CN1081035C (zh) * | 1997-11-18 | 2002-03-20 | 广州市健桥医药科技发展有限公司 | 抗疟疾新药复方萘酚喹 |
| CN1109546C (zh) * | 1998-06-17 | 2003-05-28 | 中国疾病预防控制中心寄生虫病预防控制研究所 | 青蒿素类药物与咯萘啶的复方制剂抗疟药物 |
| EP0974594A1 (fr) * | 1998-07-14 | 2000-01-26 | The Hong Kong University of Science & Technology | Dérivés d'artémisinine comme agent anti-infectieux |
| WO2001072304A1 (fr) * | 2000-03-28 | 2001-10-04 | Council Of Scientific And Industrial Research | Nouvelle composition antimicrobienne et procede de production de celle-ci |
| AU2000255631A1 (en) * | 2000-03-31 | 2001-10-15 | Council Of Scientific And Industrial Research | A synergistic anti-malarial formulation |
| AU2001295979A1 (en) * | 2000-10-20 | 2002-04-29 | Ajinomoto Co., Inc. | Medicinal compositions, dose and method for treating malaria |
| US20050148628A1 (en) * | 2002-02-13 | 2005-07-07 | Edgar Muller | Pharmaceutical combination of artesunate and mefloquine for therapy of malaria |
| WO2005023304A2 (fr) * | 2003-09-04 | 2005-03-17 | Cipla Limited | Compositions antipaludeennes et procede associe |
| BRPI0401107A (pt) * | 2004-04-13 | 2005-11-22 | Fundacao Oswaldo Cruz | Compostos derivados de artesunato, processo de preparação destes compostos, composição farmacêutica contendo os ditos compostos, uso do respectivo medicamento no tratamento ou prevenção da malária ou outras doenças parasitárias e método terapêutico |
| CH700941B1 (de) * | 2007-12-04 | 2010-11-15 | Mepha Ag | Pharmazeutische Zusammensetzung zur Behandlung von Malaria. |
| WO2013095215A1 (fr) * | 2011-12-19 | 2013-06-27 | Dilaforette Ab | Héparines anticoagulantes de faible poids moléculaire |
| EP2929881A1 (fr) * | 2014-04-11 | 2015-10-14 | CeMM - Forschungszentrum für Molekulare Medizin GmbH | Utilisation médicale de composés d'artémisinine et agonistes de géphyrine |
| CN110691597A (zh) | 2017-04-24 | 2020-01-14 | 诺华股份有限公司 | 2-氨基-1-(2-(4-氟苯基)-3-(4-氟苯基氨基)-8,8-二甲基-5,6-二氢咪唑并[1,2-a]吡嗪-7(8H)-基)乙酮及其组合的治疗方案 |
| WO2023107640A1 (fr) * | 2021-12-09 | 2023-06-15 | Incarda Therapeutics, Inc. | Thérapie inhalée pour arythmie cardiaque |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN166154B (fr) * | 1987-05-08 | 1990-03-24 | Hoechst India |
-
1989
- 1989-10-04 EP EP89118384A patent/EP0362810B1/fr not_active Expired - Lifetime
- 1989-10-04 DE DE89118384T patent/DE68906345T2/de not_active Expired - Fee Related
- 1989-10-04 ES ES89118384T patent/ES2054975T3/es not_active Expired - Lifetime
- 1989-10-05 NZ NZ230926A patent/NZ230926A/en unknown
- 1989-10-06 MX MX1787789A patent/MX17877A/es unknown
- 1989-10-06 JP JP1260344A patent/JPH02157223A/ja active Pending
- 1989-10-06 KR KR1019890014353A patent/KR900005978A/ko not_active Withdrawn
- 1989-10-06 AU AU42637/89A patent/AU4263789A/en not_active Abandoned
- 1989-10-06 CN CN89107701A patent/CN1041694A/zh active Pending
- 1989-10-06 ZA ZA897618A patent/ZA897618B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX17877A (es) | 1993-11-01 |
| EP0362810A1 (fr) | 1990-04-11 |
| ES2054975T3 (es) | 1994-08-16 |
| AU4263789A (en) | 1990-04-12 |
| KR900005978A (ko) | 1990-05-07 |
| CN1041694A (zh) | 1990-05-02 |
| EP0362810B1 (fr) | 1993-05-05 |
| NZ230926A (en) | 1992-02-25 |
| JPH02157223A (ja) | 1990-06-18 |
| DE68906345D1 (de) | 1993-06-09 |
| DE68906345T2 (de) | 1993-10-28 |
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