ZA904571B - Enantlomeric enrichment and stereoselective synthesis of chiral amines - Google Patents

Enantlomeric enrichment and stereoselective synthesis of chiral amines

Info

Publication number: ZA904571B
Authority: ZA; South Africa
Prior art keywords: enantlomeric; enrichment; stereoselective synthesis; chiral amines; chiral
Prior art date: 1989-06-22

Application number

ZA904571A

Other languages

English (en)

Inventor

David I Stirling

I Stirling David

Andrew L Zeitlin

L Zeitlin Andrew

George W Matcham

W Matcham George

Original Assignee

Celgene Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-06-22

Filing date

1990-06-13

Publication date

1991-03-27

1990-06-13 Application filed by Celgene Corp filed Critical Celgene Corp

1991-03-27 Publication of ZA904571B publication Critical patent/ZA904571B/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Analytical Chemistry (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Medicinal Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA904571A 1989-06-22 1990-06-13 Enantlomeric enrichment and stereoselective synthesis of chiral amines ZA904571B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/369,723 US4950606A (en)	1989-06-22	1989-06-22	Enantiomeric enrichment and stereoselective synthesis of chiral amines

Publications (1)

Publication Number	Publication Date
ZA904571B true ZA904571B (en)	1991-03-27

Family

ID=23456647

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA904571A ZA904571B (en)	1989-06-22	1990-06-13	Enantlomeric enrichment and stereoselective synthesis of chiral amines

Country Status (18)

Country	Link
US (1)	US4950606A (de)
EP (1)	EP0404146B1 (de)
JP (1)	JP2846074B2 (de)
KR (1)	KR0147827B1 (de)
AT (1)	ATE135744T1 (de)
AU (1)	AU628183B2 (de)
CA (1)	CA2018773C (de)
DE (1)	DE69025988T2 (de)
DK (1)	DK0404146T3 (de)
ES (1)	ES2084618T3 (de)
GR (1)	GR3019682T3 (de)
HK (1)	HK1008052A1 (de)
HU (1)	HU210967B (de)
IE (1)	IE72956B1 (de)
IL (1)	IL94694A (de)
NZ (1)	NZ234154A (de)
RU (2)	RU2087536C1 (de)
ZA (1)	ZA904571B (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3842025A1 (de) *	1988-12-14	1990-07-05	Hoechst Ag	Verfahren zur herstellung von l-phosphinothricin
US5169780A (en) *	1989-06-22	1992-12-08	Celgene Corporation	Enantiomeric enrichment and stereoselective synthesis of chiral amines
US5141904A (en) *	1991-02-15	1992-08-25	Phillips Petroleum Company	Reactivation of spent cracking catalysts
CA2077400A1 (en) *	1991-10-08	1993-04-09	Mikhail Leyderman	Mandrel and a method of making a rigid tubular article
US6534446B1 (en)	1994-02-23	2003-03-18	Emerald Bioagriculture Corporation	Method to mitigate plant stress
US5439873A (en) *	1994-02-23	1995-08-08	Plant Growth Development Corporation	Method for stimulating plant growth using GABA
US5840656A (en) *	1994-02-23	1998-11-24	Auxein Corporation	Method for increasing fertilizer efficiency
DE69635082T2 (de)	1995-10-23	2006-06-01	Kaneka Corp.	Verfahren zur herstellung optisch aktiver aminoverbindungen
JPH10165194A (ja) *	1996-12-12	1998-06-23	Sumitomo Chem Co Ltd	光学純度の向上方法
WO1998048030A1 (en) *	1997-04-23	1998-10-29	Kaneka Corporation	Process for producing optically active amino compounds
RU2213142C2 (ru) *	1998-03-11	2003-09-27	Селгро	Способ получения хирального амина
EP1045025B1 (de) *	1998-10-30	2008-10-22	Kaneka Corporation	(S)-alpha-PHENETHYLAMIN: PYRUVATTRANSAMINASE
US6432688B1 (en)	1999-01-18	2002-08-13	Daicel Chemical Industries, Ltd.	Amino alcohol dehydrogenase converts keto alcohol to amino alcohol and amino alcohol to keto alcohol
JP4496593B2 (ja) *	1999-03-19	2010-07-07	住友化学株式会社	蛋白質、その遺伝子及びその利用
DE60013939T2 (de)	1999-03-19	2005-10-06	Sumitomo Chemical Co. Ltd.	Stereoselektive Transaminase, deren kodierende Gen und deren Verwendungen
US6252114B1 (en) *	2000-03-24	2001-06-26	Council Of Scientific And Industrial Research	Process for preparing novel biologically active synthetic molecule 4-(p-methoxyphenyl)-2-amino-butane
RU2177114C2 (ru) *	2000-04-03	2001-12-20	ООО "Самаратрансгаз"	Устройство для крепления жаровой трубы в корпусе камеры сгорания
US7067291B2 (en) *	2002-12-20	2006-06-27	Pfizer Inc.	Biocatalytic preparation of enantiomerically enriched aminopentanenitrile
US20050009151A1 (en) *	2003-07-10	2005-01-13	Pharmacia Corporation	Methods for the stereospecific and enantiomeric enrichment of beta-amino acids
US7172885B2 (en) *	2004-12-10	2007-02-06	Cambrex North Brunswick, Inc.	Thermostable omega-transaminases
EP1889907B1 (de) *	2005-05-23	2009-09-02	Kaneka Corporation	Neue aminogruppentransferase, dafür codierendes gen und verfahren zur verwendung davon
EP1818411A1 (de) *	2006-02-13	2007-08-15	Lonza AG	Verfahren zur Herstellung von optisch aktiven chiralen Aminen
EP1897956A1 (de)	2006-09-06	2008-03-12	Lonza AG	Verfahren zur Herstellung von optisch aktiven Aminen durch Racematspaltung unter Verwendung einer bakteriellen omega-Transaminase
JP5253372B2 (ja)	2007-02-27	2013-07-31	マニー株式会社	かしめ装置
DE102007042600A1 (de)	2007-09-07	2009-03-12	Evonik Degussa Gmbh	Verfahren zur Herstellung von enantiomerenangereichten Aminen
CN102123999B (zh) *	2008-05-22	2014-06-18	默沙东公司	制备食欲素受体拮抗剂的方法
HUE052297T2 (hu)	2009-01-08	2021-04-28	Codexis Inc	Transzamináz polipeptidek
DE102009000592A1 (de)	2009-02-04	2010-08-05	Evonik Degussa Gmbh	Verfahren zur Herstellung von Aminogruppen tragenden, multizyklischen Ringsystemen
JP5707344B2 (ja)	2009-02-26	2015-04-30	コデクシス，インコーポレイテッド	トランスアミナーゼ生体触媒
WO2011005477A1 (en)	2009-06-22	2011-01-13	Codexis, Inc.	Transaminase reactions
HUE038434T2 (hu)	2010-06-17	2018-10-29	Codexis Inc	Biokatalizátorok és módszerek (S)-3(1-aminoetil)-fenol szintéziséhez
EP2606139B1 (de)	2010-08-16	2015-07-15	Codexis, Inc.	Biokatalysatoren und verfahren zur synthese von (1r,2r)-2-(3,4-dimethoxyphenethoxy-)cyclohexanamin
WO2014060571A1 (en) *	2012-10-18	2014-04-24	Sandoz Ag	A process for preparing indoline derivatives
SG11201504752YA (en)	2012-12-21	2015-07-30	Codexis Inc	Engineered biocatalysts and methods for synthesizing chiral amines
US9617573B2 (en)	2013-02-28	2017-04-11	Codexis, Inc.	Engineered transaminase polypeptides for industrial biocatalysis
EP3638688A4 (de)	2017-06-14	2021-07-07	Codexis, Inc.	Manipulierte transaminase-polypeptide für industrielle biokatalyse
KR20190109696A (ko)	2018-03-18	2019-09-26	양만주	재사용이 가능한 페트병 홀더
TWI851589B (zh)	2018-07-31	2024-08-11	德商拜耳廠股份有限公司	編碼改良之轉胺酶蛋白質之核酸
CA3126671A1 (en)	2019-01-15	2020-07-23	Codexis, Inc.	Engineered transaminase polypeptides
EP4133064A4 (de)	2020-04-10	2024-07-24	Codexis, Inc.	Gentechnisch hergestellte transaminasepolypeptide
IL311268A (en) *	2021-09-15	2024-05-01	Richter Gedeon Nyrt	PROCESS TO PRODUCE (1r,4r)-4-SUBSTITUTED CYCLOHEXANE-1-AMINES
CN119060058A (zh) *	2024-08-21	2024-12-03	武汉九州钰民医药科技有限公司	一种甲苯磺酸利特昔替尼的合成方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3871958A (en) *	1972-03-04	1975-03-18	Ajinomoto Kk	Biological method of producing serine and serinol derivatives
US3944617A (en) *	1976-02-20	1976-03-16	American Cyanamid Company	Synthesis of dl-2-amino-1-butanol
FI70597C (fi) *	1979-04-06	1986-09-24	Carlsberg Biotechnology Ltd	Foerfarande foer enzymatisk framstaellning av peptider
JPS55138389A (en) *	1979-04-14	1980-10-29	Denki Kagaku Kogyo Kk	Preparation of amino alcohols
JPS58198296A (ja) *	1982-05-12	1983-11-18	Chisso Corp	ｄ−２−アミノブタノ−ルの製造法
JPS5939294A (ja) *	1982-08-27	1984-03-03	Hamari Yakuhin Kogyo Kk	光学活性２−アミノ−１−ブタノ−ルの製造法
HU193902B (en) *	1983-09-01	1987-12-28	Genetics Inst	Process for preparing l-amino acids by means of transamination
IT1191638B (it) *	1985-10-31	1988-03-23	Montedison Spa	Processo per la separazione enzimatica degli isomeri ottici del 2-amminobutanolo
US4620861A (en) *	1985-11-04	1986-11-04	Corning Glass Works	Method for making index-profiled optical device
IT1188641B (it) *	1986-03-28	1988-01-20	Montedison Spa	Processo per la risoluzione enzimatica di 2-ammino-1-alcanoli racemi
JPS63237796A (ja) *	1987-03-25	1988-10-04	Kanegafuchi Chem Ind Co Ltd	光学活性１−メチル−３−フエニルプロピルアミンの製造法
JPS63273486A (ja) *	1987-04-30	1988-11-10	Tanabe Seiyaku Co Ltd	１−（４−メトキシフェニル）−２−アミノプロパンの製法
DE3818851A1 (de) *	1988-06-03	1989-12-14	Hoechst Ag	Neue transaminase, ihre herstellung und ihre verwendung

1989
- 1989-06-22 US US07/369,723 patent/US4950606A/en not_active Expired - Lifetime
1990
- 1990-06-11 IL IL9469490A patent/IL94694A/en active IP Right Grant
- 1990-06-12 CA CA002018773A patent/CA2018773C/en not_active Expired - Lifetime
- 1990-06-13 ZA ZA904571A patent/ZA904571B/xx unknown
- 1990-06-14 IE IE215990A patent/IE72956B1/en not_active IP Right Cessation
- 1990-06-19 AU AU57541/90A patent/AU628183B2/en not_active Expired
- 1990-06-20 NZ NZ234154A patent/NZ234154A/xx unknown
- 1990-06-21 EP EP90111754A patent/EP0404146B1/de not_active Expired - Lifetime
- 1990-06-21 HU HU903945A patent/HU210967B/hu unknown
- 1990-06-21 RU SU904830607A patent/RU2087536C1/ru active
- 1990-06-21 DE DE69025988T patent/DE69025988T2/de not_active Expired - Lifetime
- 1990-06-21 DK DK90111754.9T patent/DK0404146T3/da active
- 1990-06-21 AT AT90111754T patent/ATE135744T1/de not_active IP Right Cessation
- 1990-06-21 RU RU93004462A patent/RU2116347C1/ru active
- 1990-06-21 ES ES90111754T patent/ES2084618T3/es not_active Expired - Lifetime
- 1990-06-22 JP JP2165480A patent/JP2846074B2/ja not_active Expired - Lifetime
- 1990-06-22 KR KR1019900009317A patent/KR0147827B1/ko not_active Expired - Lifetime
1996
- 1996-04-19 GR GR960401061T patent/GR3019682T3/el unknown
1998
- 1998-06-27 HK HK98107175A patent/HK1008052A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
US4950606A (en)	1990-08-21
KR0147827B1 (ko)	1998-08-01
DE69025988T2 (de)	1996-08-14
IE902159L (en)	1990-12-22
IE72956B1 (en)	1997-05-07
DK0404146T3 (da)	1996-06-17
AU628183B2 (en)	1992-09-10
DE69025988D1 (de)	1996-04-25
HK1008052A1 (en)	1999-04-30
IL94694A0 (en)	1991-04-15
ATE135744T1 (de)	1996-04-15
RU2116347C1 (ru)	1998-07-27
ES2084618T3 (es)	1996-05-16
HU210967B (en)	1995-09-28
EP0404146B1 (de)	1996-03-20
KR910000616A (ko)	1991-01-29
RU2087536C1 (ru)	1997-08-20
AU5754190A (en)	1991-01-03
HU903945D0 (en)	1990-11-28
IE902159A1 (en)	1991-01-02
EP0404146A2 (de)	1990-12-27
HUT54423A (en)	1991-02-28
NZ234154A (en)	1991-08-27
JP2846074B2 (ja)	1999-01-13
EP0404146A3 (de)	1992-03-11
CA2018773C (en)	2000-03-21
GR3019682T3 (en)	1996-07-31
JPH03103192A (ja)	1991-04-30
IL94694A (en)	1996-10-16
CA2018773A1 (en)	1990-12-22

Publication	Publication Date	Title
ZA904571B (en)	1991-03-27	Enantlomeric enrichment and stereoselective synthesis of chiral amines
DK0435152T3 (da)	1997-04-21	Fremgangsmåde til enantioselektiv fremstilling af (omega-1)-hydroxyalkylxanthiner
ATE174601T1 (de)	1999-01-15	Verfahren zur herstellung von bisnoraldehyden aus bisnoralkohol
NZ242040A (en)	1993-06-25	Process for the enantiomeric enrichment of a mixture of d- and l-threo 2-amino-3-hydroxy-3-phenyl propionic acids by the use of d-threonine aldolase
NO20004036L (no)	2000-10-27	Forbedringer ved den enzymatiske syntese av kirale aminer
RU2000125535A (ru)	2003-03-27	Усовершенствования ферментативного синтеза хиральных аминов
DE68900151D1 (de)	1991-08-29	Verfahren zur herstellung von eisen-(iii)-chlorid.
DE69416424D1 (de)	1999-03-18	Verfahren zur herstellung von tert-leucin und analoge in enantiemerer form und zwischenprodukte
EP0418770A3 (en)	1991-11-27	Process for the chemical resolution of 5-alkoxy-substituted (+/-)-1,3-dimethyloxindolylethylamines
DE3781555D1 (de)	1992-10-08	Verfahren zur herstellung einer zwei diastereoisomerische n-acylaminosaeureester enthaltenden diastereoisomerischen mischung.
Baker	1975	FROM'TEIL'TO'TONSTUCK': THE SIGNIFICANCE OF THE" VERSUCH EINER ANLEITUNG ZUR COMPOSITION" BY HEINRICH CHRISTOPH KOCH.
DE58905776D1 (de)	1993-11-04	Verfahren zur herstellung von l-phosphinothricin.
DE58902228D1 (de)	1992-10-15	Verfahren zur herstellung von 5-gliedrigen, stickstoffhaltigen heteroaromaten.
ATE172727T1 (de)	1998-11-15	Verfahren zur herstellung von n-alkyl oder n- cycloalkyl-2-benzolthiazolesulfenimiden
DE69530959D1 (de)	2003-07-10	Verfahren zur Herstellung einer L-Aminosäure
ATE182329T1 (de)	1999-08-15	Verfahren zur herstellung von thioglykolsäure
DE3577314D1 (de)	1990-05-31	Verfahren zur herstellung von 2-beta-d-ribofuranosylselenazol-4-carboxamid.
Colin et al.	1991	Specific Removal of Cyanides in Effluents
ATE178054T1 (de)	1999-04-15	Verfahren zur herstellung von 2,5-dimethyl-2,5- dihydroperoxy-hexan
JPS57144989A (en)	1982-09-07	Production of amino acid by immobilized protoplast
ATE228497T1 (de)	2002-12-15	Verfahren zur herstellung von hochreinem n-formyl-leucin
ATE49978T1 (de)	1990-02-15	Verfahren zur herstellung von 7alpha,acetylthiosteroiden.