ZA9110040B - New amines,processes for the preparation thereof and pharmaceutical compositions containing them - Google Patents

New amines,processes for the preparation thereof and pharmaceutical compositions containing them

Info

Publication number: ZA9110040B
Authority: ZA; South Africa
Prior art keywords: carboxyl; group; possibly; pct; hydroxyl
Prior art date: 1990-12-24

Application number

ZA9110040A

Other languages

English (en)

Inventor

Ernst-Christian Witte

Witte Ernst-Christian

Hansjoerg Beckh

Beckh Hansjoerg

Karlheinz Stegmeier

Stegmeier Karlheinz

Liesel Doerge

Doerge Liesel

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-12-24

Filing date

1991-12-20

Publication date

1992-10-28

1991-12-20 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1992-10-28 Publication of ZA9110040B publication Critical patent/ZA9110040B/xx

Links

150000001412 amines Chemical class 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 5
125000000217 alkyl group Chemical group 0.000 abstract 4
150000001875 compounds Chemical class 0.000 abstract 3
229910052739 hydrogen Inorganic materials 0.000 abstract 3
239000001257 hydrogen Substances 0.000 abstract 3
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 3
-1 trifluoromethoxy, hydroxyl Chemical group 0.000 abstract 3
125000002252 acyl group Chemical group 0.000 abstract 2
125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 2
125000004414 alkyl thio group Chemical group 0.000 abstract 2
125000003710 aryl alkyl group Chemical group 0.000 abstract 2
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 2
125000004432 carbon atom Chemical group C* 0.000 abstract 2
150000002431 hydrogen Chemical class 0.000 abstract 2
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
150000005840 aryl radicals Chemical class 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
125000004029 hydroxymethyl group Chemical group [H]OC([H])([H])* 0.000 abstract 1
125000002883 imidazolyl group Chemical group 0.000 abstract 1
125000002092 orthoester group Chemical group 0.000 abstract 1
125000004430 oxygen atom Chemical group O* 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical group [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 abstract 1
125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/17—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/18—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms, not being part of nitro or nitroso groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pyridine Compounds (AREA)
Peptides Or Proteins (AREA)

ZA9110040A 1990-12-24 1991-12-20 New amines,processes for the preparation thereof and pharmaceutical compositions containing them ZA9110040B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4041780A DE4041780A1 (de)	1990-12-24	1990-12-24	Neue amine, verfahren zu ihrer herstellung, sowie diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number	Publication Date
ZA9110040B true ZA9110040B (en)	1992-10-28

Family

ID=6421442

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9110040A ZA9110040B (en)	1990-12-24	1991-12-20	New amines,processes for the preparation thereof and pharmaceutical compositions containing them

Country Status (16)

Country	Link
US (1)	US5446065A (fr)
EP (1)	EP0564499B1 (fr)
JP (1)	JPH06503822A (fr)
AT (1)	ATE121076T1 (fr)
AU (1)	AU662308B2 (fr)
CA (1)	CA2098929A1 (fr)
DE (2)	DE4041780A1 (fr)
FI (1)	FI932895A7 (fr)
HU (1)	HUT68720A (fr)
IE (1)	IE914467A1 (fr)
IL (1)	IL100476A0 (fr)
MX (1)	MX9102772A (fr)
NZ (1)	NZ241117A (fr)
PT (1)	PT99924A (fr)
WO (1)	WO1992011234A1 (fr)
ZA (1)	ZA9110040B (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU5772196A (en) *	1995-05-19	1996-11-29	Chiroscience Limited	3,4-disubstituted-phenylsulphonamides and their therapeutic use
BE1012386A3 (fr) *	1999-01-15	2000-10-03	Univ Liege	Derives de sulfonamides benzeniques et leurs utilisations.
US6552225B1 (en) *	1999-09-04	2003-04-22	Astrazeneca Ab	Chemical compounds
PL377314A1 (pl) *	2002-12-20	2006-01-23	Amgen Inc.	Modulatory astmy i zapaleń na tle alergicznym
EP1696915A1 (fr) *	2003-12-19	2006-09-06	Pfizer, Inc.	Derives de benzenesulfonylamino-pyridin-2yl et composes apparentes en tant qu'inhibiteurs de la 11-beta-hydeoxysteroide deshydrogenase type 1 (11-beta-hsd-1) pour le traitement du diabete et de l'obesite
MY156662A (en) *	2007-11-01	2016-03-15	Acucela Inc	Amine derivative compounds for treating ophthalmic diseases and disorders

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4003929A (en) *	1975-03-11	1977-01-18	Pfizer Inc.	Antiviral substituted phenylenedimethylene diamines
US4064125A (en) *	1976-10-29	1977-12-20	E. R. Squibb And Sons, Inc.	Substituted amides having antiinflammatory activity
DE2809377A1 (de) *	1978-03-04	1979-09-13	Boehringer Mannheim Gmbh	Phenoxyalkylcarbonsaeure-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel
US4539426A (en) *	1984-05-11	1985-09-03	American Home Products Corporation	Anti-arrhythmic agents
DE68909958D1 (de) *	1988-01-19	1993-11-25	Tanabe Seiyaku Co	Phenoxyessigsäure-Derivate, ihre Herstellung, pharmazeutische Zusammensetzungen, die sie enthalten, und deren Verwendung.
DE3829431A1 (de) *	1988-08-31	1990-03-01	Boehringer Mannheim Gmbh	Sulfonamide mit tetrazolylrest, verfahren zur ihrer herstellung sowie arzneimittel

1990
- 1990-12-24 DE DE4041780A patent/DE4041780A1/de not_active Withdrawn
1991
- 1991-12-19 DE DE59105207T patent/DE59105207D1/de not_active Expired - Fee Related
- 1991-12-19 CA CA002098929A patent/CA2098929A1/fr not_active Abandoned
- 1991-12-19 HU HU9301853A patent/HUT68720A/hu unknown
- 1991-12-19 EP EP92901147A patent/EP0564499B1/fr not_active Expired - Lifetime
- 1991-12-19 AT AT92901147T patent/ATE121076T1/de not_active IP Right Cessation
- 1991-12-19 AU AU90889/91A patent/AU662308B2/en not_active Ceased
- 1991-12-19 US US08/075,489 patent/US5446065A/en not_active Expired - Fee Related
- 1991-12-19 WO PCT/EP1991/002456 patent/WO1992011234A1/fr not_active Ceased
- 1991-12-19 JP JP4501160A patent/JPH06503822A/ja active Pending
- 1991-12-20 IE IE446791A patent/IE914467A1/en unknown
- 1991-12-20 ZA ZA9110040A patent/ZA9110040B/xx unknown
- 1991-12-20 NZ NZ241117A patent/NZ241117A/en unknown
- 1991-12-23 PT PT99924A patent/PT99924A/pt not_active Application Discontinuation
- 1991-12-23 MX MX9102772A patent/MX9102772A/es unknown
- 1991-12-23 IL IL100476A patent/IL100476A0/xx unknown
1993
- 1993-06-23 FI FI932895A patent/FI932895A7/fi unknown

Also Published As

Publication number	Publication date
IE914467A1 (en)	1992-07-01
FI932895A0 (fi)	1993-06-23
HU9301853D0 (en)	1993-09-28
DE4041780A1 (de)	1992-06-25
AU9088991A (en)	1992-07-22
IL100476A0 (en)	1992-09-06
EP0564499B1 (fr)	1995-04-12
US5446065A (en)	1995-08-29
HUT68720A (en)	1995-07-28
ATE121076T1 (de)	1995-04-15
MX9102772A (es)	1992-06-01
EP0564499A1 (fr)	1993-10-13
DE59105207D1 (de)	1995-05-18
AU662308B2 (en)	1995-08-31
WO1992011234A1 (fr)	1992-07-09
NZ241117A (en)	1994-11-25
PT99924A (pt)	1993-01-29
JPH06503822A (ja)	1994-04-28
FI932895A7 (fi)	1993-06-23
CA2098929A1 (fr)	1992-06-25

Publication	Publication Date	Title
EP0184095A3 (en)	1987-04-22	Bisacylphosphinoxides, their preparation and use
IL68075A0 (en)	1983-06-15	Pyridine and pyrane derivatives,their preparation and pharmaceutical compositions containing them
MD420C2 (ro)	1997-04-30	Derivaţi ai acidului acrilic
ES482888A1 (es)	1980-04-16	Procedimiento para la preparacion de nuevos heterociclos sustituidos en n
HUT61575A (en)	1993-01-28	Process for producing n-acetamido-n-phenyl glycineamide derivatives and pharmaceutical compositions comprising same
HUT61576A (en)	1993-01-28	Process for producing n-phenyl glycineamide derivatives and pharmaceutical compositions comprising same
IL79841A (en)	1992-02-16	2,3-dihydro-1,3,4-thiadiazole 2-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
ZA9110040B (en)	1992-10-28	New amines,processes for the preparation thereof and pharmaceutical compositions containing them
CA1249830A (fr)	1989-02-07	Antihistaminiques a groupements diphenyle et phenylpyridyle
DE3362504D1 (en)	1986-04-17	1-carboxyalkanoylindoline-2-carboxylic-acid esters, their preparation, pharmaceutical compositions containing them, and their therapeutic use
DE69101673D1 (de)	1994-05-19	N-substituierte Alpha-Mercaptoalkylaminderivate, Verfahren zu ihrer Herstellung und hergestellte Zwischenprodukte, ihre Verwendung als Arzneimittel und diese enthaltende Zusammensetzungen.
NZ218453A (en)	1989-01-06	Pharmaceutical compositions containing a synergistic mixture of a dihydropyridine derivative and pyridazodiazepine derivative
ES453162A1 (es)	1977-11-01	Un procedimiento para la obtencion de compuestos heteroci- clicos.
MY113529A (en)	2002-03-30	New derivatives of imidazole n- benzyldioxole,processes for their preparation, their use as medicaments and pharmaceutical compositions containing them
IL98546A0 (en)	1992-07-15	Ace inhibitor ester derivatives,their preparation and pharmaceutical compositions containing them
IL97270A0 (en)	1992-05-25	N-phenyl n-alkoxycarbonylalkyl glycinamides,their preparation and medications containing the same
ES483253A1 (es)	1980-09-01	Un procedimiento para la prepracion de derivados de pipera- zin-2,5-diona.
ES378917A1 (es)	1973-01-16	Metodo para preparar una amida formacodinamicamente activa.
ES8306099A1 (es)	1983-05-01	Un procedimiento para la preparacion de derivados de acido 2-(2-cianoetil)-2-benzoilamino-alcanoicos.
EP0292981A3 (en)	1989-02-22	2-selenomethyl-1, 4-dihydropyridines a process for the preparation thereof and pharmaceutical compositions containing them
ES8103749A1 (es)	1981-03-16	Procedimiento para la preparacion de 5,6,7,8-tetrahidropira-zolo (3,4-b)(1,5)diazepin-1h,4h-5,7-dionas
DE2963724D1 (en)	1982-11-04	Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them