ZA912398B - Stable compositions for parenteral administration and method of making same - Google Patents

Stable compositions for parenteral administration and method of making same

Info

Publication number
ZA912398B
ZA912398B ZA912398A ZA912398A ZA912398B ZA 912398 B ZA912398 B ZA 912398B ZA 912398 A ZA912398 A ZA 912398A ZA 912398 A ZA912398 A ZA 912398A ZA 912398 B ZA912398 B ZA 912398B
Authority
ZA
South Africa
Prior art keywords
parenteral administration
making same
stable compositions
compositions
stable
Prior art date
Application number
ZA912398A
Other languages
English (en)
Inventor
William Steber
Steber William
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ZA912398B publication Critical patent/ZA912398B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/27—Growth hormone [GH], i.e. somatotropin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
ZA912398A 1990-03-30 1991-03-28 Stable compositions for parenteral administration and method of making same ZA912398B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/502,382 US5213810A (en) 1990-03-30 1990-03-30 Stable compositions for parenteral administration and method of making same

Publications (1)

Publication Number Publication Date
ZA912398B true ZA912398B (en) 1992-01-29

Family

ID=23997559

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA912398A ZA912398B (en) 1990-03-30 1991-03-28 Stable compositions for parenteral administration and method of making same

Country Status (28)

Country Link
US (1) US5213810A (fr)
EP (1) EP0448930B1 (fr)
JP (1) JP2966564B2 (fr)
KR (1) KR0159778B1 (fr)
CN (1) CN1063941C (fr)
AR (1) AR248085A1 (fr)
AT (1) ATE106240T1 (fr)
AU (1) AU641994B2 (fr)
BG (1) BG60850B1 (fr)
CA (1) CA2039491C (fr)
CZ (1) CZ283053B6 (fr)
DE (1) DE69102176T2 (fr)
DK (1) DK0448930T3 (fr)
ES (1) ES2054380T3 (fr)
FI (1) FI101676B1 (fr)
HU (1) HU219584B (fr)
IE (1) IE65970B1 (fr)
IL (1) IL97145A (fr)
MX (1) MX172602B (fr)
NO (1) NO300717B1 (fr)
NZ (1) NZ237509A (fr)
PL (1) PL167692B1 (fr)
PT (1) PT97160B (fr)
RO (1) RO106191B1 (fr)
RU (1) RU2011377C1 (fr)
SK (1) SK279461B6 (fr)
YU (1) YU47650B (fr)
ZA (1) ZA912398B (fr)

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AU6029694A (en) * 1993-01-19 1994-08-15 Pharmacia P-L Biochemicals, Inc. Storage and delivery of purified protein reagents with carrier wax
US5599660A (en) * 1993-01-19 1997-02-04 Pharmacia Biotech Inc. Method and preparation for sequential delivery of wax-embedded, inactivated biological and chemical reagents
US5683720A (en) * 1994-10-28 1997-11-04 Fuisz Technologies Ltd. Liquiflash particles and method of making same
US6083430A (en) * 1994-10-28 2000-07-04 Fuisz Technologies Ltd. Method of preparing a dosage unit by direct tableting and product therefrom
DE69616167T2 (de) * 1995-06-29 2002-06-20 Societe Des Produits Nestle S.A., Vevey Verfahren zur Verkapselung eines Kernmaterials mit einem Polymer durch Hochdruckbehandlung
WO1999013864A2 (fr) * 1997-09-19 1999-03-25 Shire Laboratories, Inc. Granule de solution solide
AU2002300572B2 (en) * 1997-09-19 2004-11-25 Shire Laboratories, Inc. Solid Solution Beadlet
US6117452A (en) * 1998-08-12 2000-09-12 Fuisz Technologies Ltd. Fatty ester combinations
MXPA01011343A (es) * 1999-05-07 2002-06-04 Pharmasol Gmbh Particulas de lipidos a base de mezclas de lipidos liquidos y solidos asi como procedimiento para su produccion.
KR20020011985A (ko) * 1999-05-07 2002-02-09 파르마솔 게엠베하 액상 및 고체상 지질 혼합물에 기초한 지질입자들 및 그의제조방법
CA2376202C (fr) * 1999-06-07 2008-11-18 Byk Gulden Lomberg Chemische Fabrik Gmbh Preparation et forme galenique comprenant un compose actif acido-labile
CN1164334C (zh) * 1999-08-18 2004-09-01 研究及应用科学协会股份有限公司 肽的缓释制剂
IES990700A2 (en) * 1999-08-18 2001-08-22 Kinerton Ltd Process to make a sustained release formulation
CA2407154A1 (fr) 2000-04-27 2001-11-01 Verion, Inc Microcapsules a liberation d'ordre nul et commande par la temperature, et procede pour leur elaboration
AU2001273028B2 (en) * 2000-06-26 2006-11-16 Dsm Ip Assets B.V. Improved methods of incorporating polyunsaturated fatty acids in milk
JP2004509739A (ja) 2000-09-27 2004-04-02 ベリオン　インコーポレイテッド 即時水溶解性カプセルおよびその製法
EP1197207B1 (fr) * 2000-10-10 2008-04-23 Wyeth Holdings Corporation Compositions stabilisées pour l'administration parentérale
FR2852843B1 (fr) 2003-03-24 2008-05-23 Karim Ioualalen Systeme galenique permettant le masquage du gout
ATE399536T1 (de) * 2003-12-04 2008-07-15 Pfizer Prod Inc Verfahren zur herstellung von pharmazeutischen multiteilchenförmigen produkten
US6984403B2 (en) * 2003-12-04 2006-01-10 Pfizer Inc. Azithromycin dosage forms with reduced side effects
CA2549225A1 (fr) * 2003-12-04 2005-06-16 Pfizer Products Inc. Procede d'atomisation/congelation faisant appel a une extrudeuse pour la preparation de compositions medicamenteuses cristallines multiparticulaires contenant de preference un poloxamere et un glyceride
WO2005053639A2 (fr) * 2003-12-04 2005-06-16 Pfizer Products Inc. Formes multiparticulaires a liberation controlee produites avec des optimiseurs de dissolution
CN1889931A (zh) * 2003-12-04 2007-01-03 辉瑞产品公司 利用挤压器制备优选含泊洛沙姆和甘油酯的多重粒子阿奇霉素组合物的喷雾－冻凝方法
EP1694304A2 (fr) * 2003-12-04 2006-08-30 Pfizer Products Inc. Formes de dosage multiparticulaire d'azythromycine obtenue par des procedes a base de liquide
WO2005053652A1 (fr) 2003-12-04 2005-06-16 Pfizer Products Inc. Compositions medicamenteuses cristallines multiparticulaires contenant un poloxamere et un glyceride
BRPI0416534A (pt) * 2003-12-04 2007-01-09 Pfizer Prod Inc composições multiparticuladas com estabilidade melhorada
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
US8221809B2 (en) * 2006-06-22 2012-07-17 Martek Biosciences Corporation Encapsulated labile compound compositions and methods of making the same
EP2049081B1 (fr) 2006-08-09 2012-11-14 Intarcia Therapeutics, Inc. Systemes d'administration osmotiques et ensembles pistons
HRP20130259T1 (hr) 2007-04-23 2013-04-30 Intarcia Therapeutics, Inc. Suspenzijske formulacije inzulinotropnih peptida i njihove uporabe
DK2240155T3 (da) 2008-02-13 2012-09-17 Intarcia Therapeutics Inc Indretninger, formuleringer og fremgangsmåder til levering af flere gavnlige midler
KR101760953B1 (ko) * 2008-09-04 2017-07-24 아밀린 파마슈티칼스, 엘엘씨. 비-수성 담체를 이용한 서방성 제형물
JP5494957B2 (ja) 2009-06-11 2014-05-21 株式会社リコー 静電荷像現像用トナー、現像剤、画像形成方法及び画像形成装置
SMT201700583T1 (it) 2009-09-28 2018-01-11 Intarcia Therapeutics Inc Instaurazione e/o terminazione rapida di erogazione di farmaci in modo sostanzialmente stazionario
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
US9364549B2 (en) * 2011-11-30 2016-06-14 Andreas Voigt Hydrophobic drug-delivery material, method for manufacturing thereof and methods for delivery of a drug-delivery composition
US20160151286A1 (en) * 2013-05-29 2016-06-02 Therakine Biodelivery Gmbh Hydrophilic Microparticles, Drug-Delivery Material, Method For Manufacturing Thereof And Methods For Delivery of A Drug-Delivery Composition
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
US10925639B2 (en) 2015-06-03 2021-02-23 Intarcia Therapeutics, Inc. Implant placement and removal systems
RU2760007C2 (ru) 2016-05-16 2021-11-22 Интарсия Терапьютикс, Инк. Полипептиды, селективные к рецепторам глюкагона, и способы их применения
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
CN110225762A (zh) 2017-01-03 2019-09-10 因塔西亚制药公司 包括glp-1受体激动剂的连续施用和药物的共同施用的方法
EP3927715A4 (fr) 2019-02-21 2023-03-01 Chromadex, Inc. Utilisation de nicotinamide riboside, d'acide nicotinique riboside, de composés à nicotinyl riboside réduits et de dérivés de composé de nicotinyl riboside dans des formulations

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US3147187A (en) * 1962-09-10 1964-09-01 Don Hall Lab Sustained release pharmaceutical
CH637297A5 (fr) * 1978-12-05 1983-07-29 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication.
JPS56140915A (en) * 1980-04-07 1981-11-04 Yamanouchi Pharmaceut Co Ltd Pharmaceutical preparation for solid drug
US4331654A (en) * 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
DE3024416C2 (de) * 1980-06-28 1982-04-15 Gödecke AG, 1000 Berlin Verfahren zur Herstellung von Arzneimitteln mit retardierter Wirkstoff-Freisetzung
US4666839A (en) * 1982-12-01 1987-05-19 Amgen Methods and materials for obtaining microbial expression of polypeptides including bovine prolactin
US4452775A (en) * 1982-12-03 1984-06-05 Syntex (U.S.A.) Inc. Cholesterol matrix delivery system for sustained release of macromolecules
US4603044A (en) * 1983-01-06 1986-07-29 Technology Unlimited, Inc. Hepatocyte Directed Vesicle delivery system
US4568559A (en) * 1984-02-06 1986-02-04 Biotek, Inc. Composite core coated microparticles and process of preparing same
US4568536A (en) * 1985-02-08 1986-02-04 Ethicon, Inc. Controlled release of pharmacologically active agents from an absorbable biologically compatible putty-like composition
US4755387A (en) * 1985-03-21 1988-07-05 The Procter & Gamble Company Therapeutic particles
DE3527356A1 (de) * 1985-07-31 1987-02-05 Degussa Verfahren zur verbesserung der fruchtbarkeit von haustieren
SE462894B (sv) * 1985-10-28 1990-09-17 Biogram Ab Mikrokapslar, foerfarande foer framstaellning daerav samt anvaendning
US4837381A (en) * 1986-08-11 1989-06-06 American Cyanamid Company Compositions for parenteral administration and their use
US4911928A (en) * 1987-03-13 1990-03-27 Micro-Pak, Inc. Paucilamellar lipid vesicles

Also Published As

Publication number Publication date
FI101676B (fi) 1998-08-14
IL97145A0 (en) 1992-05-25
CZ283053B6 (cs) 1997-12-17
EP0448930B1 (fr) 1994-06-01
FI911531A0 (fi) 1991-03-28
HK1000004A1 (en) 1997-10-03
EP0448930A1 (fr) 1991-10-02
HU219584B (hu) 2001-05-28
KR910016322A (ko) 1991-11-05
YU47650B (sh) 1995-12-04
US5213810A (en) 1993-05-25
BG93923A (bg) 1993-12-24
DE69102176D1 (de) 1994-07-07
FI911531L (fi) 1991-10-01
HUT59834A (en) 1992-07-28
FI101676B1 (fi) 1998-08-14
KR0159778B1 (ko) 1998-12-01
AU641994B2 (en) 1993-10-07
IE65970B1 (en) 1995-11-29
RO106191B1 (ro) 1993-03-31
CN1063941C (zh) 2001-04-04
YU57091A (sh) 1994-01-20
DE69102176T2 (de) 1995-01-05
HU911054D0 (en) 1991-10-28
PL167692B1 (en) 1995-10-31
PT97160B (pt) 1998-07-31
MX172602B (es) 1993-01-03
NO911228L (no) 1991-10-01
BG60850B1 (bg) 1996-05-31
ES2054380T3 (es) 1994-08-01
PT97160A (pt) 1991-11-29
JPH04221319A (ja) 1992-08-11
NO300717B1 (no) 1997-07-14
AU7397291A (en) 1991-10-03
NZ237509A (en) 1993-04-28
CA2039491A1 (fr) 1991-10-01
CN1055293A (zh) 1991-10-16
NO911228D0 (no) 1991-03-26
IL97145A (en) 1996-06-18
AR248085A1 (es) 1995-06-30
RU2011377C1 (ru) 1994-04-30
CA2039491C (fr) 2001-09-04
IE911041A1 (en) 1991-10-09
JP2966564B2 (ja) 1999-10-25
ATE106240T1 (de) 1994-06-15
SK279461B6 (sk) 1998-11-04
PL289657A1 (en) 1992-01-13
DK0448930T3 (da) 1994-06-20

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