ZA912498B - Novel platelet-aggregation inhibitors - Google Patents

Novel platelet-aggregation inhibitors

Info

Publication number
ZA912498B
ZA912498B ZA912498A ZA912498A ZA912498B ZA 912498 B ZA912498 B ZA 912498B ZA 912498 A ZA912498 A ZA 912498A ZA 912498 A ZA912498 A ZA 912498A ZA 912498 B ZA912498 B ZA 912498B
Authority
ZA
South Africa
Prior art keywords
aggregation inhibitors
novel platelet
platelet
novel
aggregation
Prior art date
Application number
ZA912498A
Other languages
English (en)
Inventor
Mark Christopher Allen
Christopher Allen Mark
Peter Daniel Kane
Daniel Kane Peter
Roy Wade
Wade Roy
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of ZA912498B publication Critical patent/ZA912498B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
ZA912498A 1990-04-05 1991-04-04 Novel platelet-aggregation inhibitors ZA912498B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909007751A GB9007751D0 (en) 1990-04-05 1990-04-05 Novel platelet-aggregation inhibitors

Publications (1)

Publication Number Publication Date
ZA912498B true ZA912498B (en) 1992-01-29

Family

ID=10673967

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA912498A ZA912498B (en) 1990-04-05 1991-04-04 Novel platelet-aggregation inhibitors

Country Status (13)

Country Link
EP (1) EP0452257A3 (de)
JP (1) JPH0770174A (de)
KR (1) KR910018404A (de)
AU (1) AU7410191A (de)
CA (1) CA2039628A1 (de)
FI (1) FI911606A7 (de)
GB (1) GB9007751D0 (de)
IE (1) IE911127A1 (de)
NO (1) NO911327L (de)
NZ (1) NZ237674A (de)
PT (1) PT97237A (de)
TW (1) TW206238B (de)
ZA (1) ZA912498B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5332726A (en) * 1989-09-29 1994-07-26 Rhone-Poulenc Rorer Pharmaceuticals Inc. Antithrombotic peptides and pseudopeptides
JPH08503920A (ja) * 1991-04-11 1996-04-30 ローヌ−プーラン ローラー インターナショナル（ホウルディングス） インコーポレイテッド 抗血栓ペプチドおよび偽ペプチド誘導体
DE4126277A1 (de) * 1991-08-08 1993-02-11 Cassella Ag Hydantoinderivate
CA2101599A1 (en) * 1992-08-31 1994-03-01 Wilhelm Bannwarth Tri- and tetracyclic compounds
WO1994022834A1 (en) * 1993-03-29 1994-10-13 Zeneca Limited Heterocyclic derivatives as platelet aggregation inhibitors
GB9406144D0 (en) * 1993-03-29 1994-05-18 Zeneca Ltd Heterocyclic compounds
US5753659A (en) * 1993-03-29 1998-05-19 Zeneca Limited Heterocyclic compouds
US5652242A (en) * 1993-03-29 1997-07-29 Zeneca Limited Heterocyclic derivatives
US5750754A (en) * 1993-03-29 1998-05-12 Zeneca Limited Heterocyclic compounds
GB9313268D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Chemical compounds
GB9313285D0 (en) * 1993-06-28 1993-08-11 Zeneca Ltd Acid derivatives
US5463011A (en) * 1993-06-28 1995-10-31 Zeneca Limited Acid derivatives
US5780590A (en) * 1993-10-15 1998-07-14 Rhone-Poulenc Rorer Pharmaceuticals Inc. Antithrombotic azacycloalkylalkanoyl peptides and pseudopeptides
DE19621638C2 (de) * 1996-05-30 2002-06-27 Fraunhofer Ges Forschung Offenzellige Schaumkeramik mit hoher Festigkeit und Verfahren zu deren Herstellung
DE19632773A1 (de) * 1996-08-14 1998-02-19 Basf Ag Neue Thrombininhibitoren
GB9826751D0 (en) 1998-12-05 1999-01-27 British Aerospace Method for increasing the signal to noise ratio in non-destructive testing

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3781263T2 (de) * 1986-12-15 1993-04-08 Inst Nat Sante Rech Med Peptid-derivate und deren verwendung in der therapie.
CA2008116C (en) * 1989-02-23 2001-11-20 Thomas Weller Glycine derivatives

Also Published As

Publication number Publication date
FI911606A0 (fi) 1991-04-03
IE911127A1 (en) 1991-10-09
JPH0770174A (ja) 1995-03-14
EP0452257A3 (en) 1992-09-02
AU7410191A (en) 1991-10-10
PT97237A (pt) 1992-01-31
EP0452257A2 (de) 1991-10-16
NO911327D0 (no) 1991-04-04
GB9007751D0 (en) 1990-06-06
TW206238B (de) 1993-05-21
NO911327L (no) 1991-10-07
NZ237674A (en) 1992-07-28
KR910018404A (ko) 1991-11-30
CA2039628A1 (en) 1991-10-06
FI911606A7 (fi) 1991-10-06

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