ZA912766B - Combination of pravastatin and a fibric acid derivative,and method for treating dyslipidemia using such combination - Google Patents

Combination of pravastatin and a fibric acid derivative,and method for treating dyslipidemia using such combination

Info

Publication number: ZA912766B
Authority: ZA; South Africa
Prior art keywords: combination; pravastatin; acid derivative; fibric acid; treating dyslipidemia
Prior art date: 1990-04-30

Application number

ZA912766A

Other languages

English (en)

Inventor

Henry Y Pan

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-30

Filing date

1991-04-12

Publication date

1992-01-29

1991-04-12 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1992-01-29 Publication of ZA912766B publication Critical patent/ZA912766B/xx

Links

ILPUOPPYSQEBNJ-UHFFFAOYSA-N 2-methyl-2-phenoxypropanoic acid Chemical class OC(=O)C(C)(C)OC1=CC=CC=C1 ILPUOPPYSQEBNJ-UHFFFAOYSA-N 0.000 title 1
208000032928 Dyslipidaemia Diseases 0.000 title 1
208000017170 Lipid metabolism disease Diseases 0.000 title 1
TUZYXOIXSAXUGO-UHFFFAOYSA-N Pravastatin Natural products C1=CC(C)C(CCC(O)CC(O)CC(O)=O)C2C(OC(=O)C(C)CC)CC(O)C=C21 TUZYXOIXSAXUGO-UHFFFAOYSA-N 0.000 title 1
229940125753 fibrate Drugs 0.000 title 1
229960002965 pravastatin Drugs 0.000 title 1
TUZYXOIXSAXUGO-PZAWKZKUSA-N pravastatin Chemical compound C1=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@H]2[C@@H](OC(=O)[C@@H](C)CC)C[C@H](O)C=C21 TUZYXOIXSAXUGO-PZAWKZKUSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Epidemiology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ZA912766A 1990-04-30 1991-04-12 Combination of pravastatin and a fibric acid derivative,and method for treating dyslipidemia using such combination ZA912766B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US51686590A	1990-04-30	1990-04-30

Publications (1)

Publication Number	Publication Date
ZA912766B true ZA912766B (en)	1992-01-29

Family

ID=24057426

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA912766A ZA912766B (en)	1990-04-30	1991-04-12	Combination of pravastatin and a fibric acid derivative,and method for treating dyslipidemia using such combination

Country Status (9)

Country	Link
EP (1)	EP0455042A1 (de)
JP (1)	JPH04225916A (de)
KR (1)	KR910018020A (de)
AU (1)	AU7626991A (de)
CA (1)	CA2039763A1 (de)
HU (1)	HU911443D0 (de)
IE (1)	IE911364A1 (de)
PT (1)	PT97523A (de)
ZA (1)	ZA912766B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20030105154A1 (en)	2001-10-24	2003-06-05	Bisgaier Charles Larry	Statin-carboxyalkylether combinations
SK288117B6 (sk)	1998-11-20	2013-09-03	Skyepharma Canada Inc.	Rapidly dispersing solid dry therapeutic dosage form
DE19858789A1 (de) *	1998-12-18	2000-06-21	Bayer Ag	Kombination von Cerivastatin und Fibraten
US6982251B2 (en)	2000-12-20	2006-01-03	Schering Corporation	Substituted 2-azetidinones useful as hypocholesterolemic agents
IL156445A0 (en)	2001-01-26	2004-01-04	Schering Corp	Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
US7071181B2 (en)	2001-01-26	2006-07-04	Schering Corporation	Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
AR035533A1 (es)	2001-01-26	2004-06-02	Schering Corp	Uso de por lo menos un inhibidor de la absorcion de los esteroles o sus sales, solvatos, prodrogas farmaceuticamente aceptables o mezclas de los mismos para la preparacion de un medicamento para el tratamiento de la sitosterolemia, composiciones farmaceuticas, el uso de dichas composiciones para la
US7067148B2 (en)	2001-02-15	2006-06-27	King Pharmaceutical Research & Development, Inc.	Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
US20020198202A1 (en) *	2001-06-07	2002-12-26	Wyeth	Combination of a PTPase inhibitor and an antilipemic agent
CA2456732C (en)	2001-08-07	2012-10-30	Galephar M/F	Oral pharmaceutical composition containing a combination of ppar.alpha. and a hmg-coa reductase inhibitor
WO2003013607A1 (en) *	2001-08-07	2003-02-20	Galephar M/F	ORAL PHARMACEUTICAL COMPOSITION CONTAINING A COMBINATION OF FENOFIBRATE AND A HMG-CoA REDUCTASE INHIBITOR
US7101569B2 (en)	2001-08-14	2006-09-05	Franz G Andrew	Methods of administering levothyroxine pharmaceutical compositions
US7056906B2 (en)	2001-09-21	2006-06-06	Schering Corporation	Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
US7053080B2 (en)	2001-09-21	2006-05-30	Schering Corporation	Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
MXPA04002573A (es)	2001-09-21	2004-06-18	Schering Corp	Tratamiento de xantoma con derivados de azetidinona como inhibidores de la absorcion de esterol.
DE10200138A1 (de) *	2002-01-04	2003-07-17	Karl Winkler	Kombination von einem PPAR-Agonisten mit PPAR-alpha Aktivität mit einem Induktor des LDL-Rezeptors
WO2004043457A1 (en)	2002-11-06	2004-05-27	Schering Corporation	Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
CA2517572C (en)	2003-03-07	2011-12-13	Schering Corporation	Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7459442B2 (en)	2003-03-07	2008-12-02	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP2006519869A (ja)	2003-03-07	2006-08-31	シェーリング　コーポレイション	置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
EP1601668B1 (de)	2003-03-07	2008-08-27	Schering Corporation	Substituierte azetidinon-derivate, deren pharmazeutische formulierungen und deren verwendung zur behandlung von hypercholesterolemia
ATE428411T1 (de)	2003-11-07	2009-05-15	Jj Pharma Inc	Hdl-verstärkende kombinationstherapie-komplexe
WO2006002127A1 (en) *	2004-06-21	2006-01-05	Fairfield Clinical Trials, Llc	Transdermal delivery system for statin combination therapy
EP1853249A2 (de) *	2005-02-10	2007-11-14	LifeCycle Pharma A/S	Stabile pharmazeutische zusammensetzung aus einer fixdosen-kombination von fenofibrat und einem hmg-coa-reductase-hemmer
WO2007106912A2 (en) *	2006-03-16	2007-09-20	University Of Pittsburgh Of The Commonwealth System Of Higher Education	Peroxisome-proliferator activated receptor-alpha agonists for organ preservation
GB0713707D0 (en) *	2007-07-13	2007-08-22	Generics Uk Ltd	Stable compositions
AU2016348638A1 (en)	2015-11-06	2018-06-07	Gemphire Therapeutics Inc.	Gemcabene combinations for the treatment of cardiovascular disease

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU1422388A (en) *	1987-01-27	1988-08-10	Warner-Lambert Company	Lipid regulating compositions

1991
- 1991-04-04 CA CA002039763A patent/CA2039763A1/en not_active Abandoned
- 1991-04-12 ZA ZA912766A patent/ZA912766B/xx unknown
- 1991-04-16 EP EP91106054A patent/EP0455042A1/de not_active Withdrawn
- 1991-04-24 IE IE136491A patent/IE911364A1/en unknown
- 1991-04-26 AU AU76269/91A patent/AU7626991A/en not_active Abandoned
- 1991-04-29 HU HU911443A patent/HU911443D0/hu unknown
- 1991-04-29 KR KR1019910006857A patent/KR910018020A/ko not_active Withdrawn
- 1991-04-30 JP JP3098623A patent/JPH04225916A/ja not_active Withdrawn
- 1991-04-30 PT PT97523A patent/PT97523A/pt not_active Application Discontinuation

Also Published As

Publication number	Publication date
JPH04225916A (ja)	1992-08-14
IE911364A1 (en)	1991-11-06
PT97523A (pt)	1992-01-31
CA2039763A1 (en)	1991-10-31
EP0455042A1 (de)	1991-11-06
HU911443D0 (en)	1991-11-28
AU7626991A (en)	1991-11-07
KR910018020A (ko)	1991-11-30

Publication	Publication Date	Title
ZA912766B (en)	1992-01-29	Combination of pravastatin and a fibric acid derivative,and method for treating dyslipidemia using such combination
HU9302034D0 (en)	1993-11-29	Plant protecting preparatives containing hetero-aromatic compounds and method for producing said active agents
GB9027968D0 (en)	1991-02-13	Method of treatment
PL301482A1 (en)	1994-06-27	Method of obtaining cellulose carbamate
GB2269114B (en)	1995-10-18	Method of removing catalyst
GB9218027D0 (en)	1992-10-14	Novel method of treatment
EP0469443A3 (en)	1992-05-27	Method of treating waste
GB9202196D0 (en)	1992-03-18	Method of treatment
PH30221A (en)	1997-02-05	Method of treating ketosis
GB9218597D0 (en)	1992-10-14	Novel method of treatment
GB9201391D0 (en)	1992-03-11	Method of treatment
RU1769863C (ru)	1992-10-23	Cпocoб haлoжehия xoлeдoxoдуoдehoahactomoзa
HU9301187D0 (en)	1993-07-28	Method for treating tumours being dependent of gar-transformylase
HU9200202D0 (en)	1992-04-28	A new method for treatment of bank-books
GB9226371D0 (en)	1993-02-10	Novel method of treatment
GB9205945D0 (en)	1992-04-29	Method of treating yarn
GB9208425D0 (en)	1992-06-03	Method of treating yarn
GB9218188D0 (en)	1992-10-14	Method of treatment
GB9223252D0 (en)	1992-12-23	Method of treatment
GB9202698D0 (en)	1992-03-25	Method of treatment
GB9202020D0 (en)	1992-03-18	Method of treatment
GB9207275D0 (en)	1992-05-13	Method of treatment
GB9226252D0 (en)	1993-02-10	Method of treatment
RU1833722C (ru)	1993-08-15	Cпocoб лeчehия cиhдaktилии
RU1769867C (ru)	1992-10-23	Cпocoб лeчehия octeomиeлиta