ZA912877B - Enzymatic synthesis of soluble phosphatides from phospholipids - Google Patents

Enzymatic synthesis of soluble phosphatides from phospholipids

Info

Publication number
ZA912877B
ZA912877B ZA912877A ZA912877A ZA912877B ZA 912877 B ZA912877 B ZA 912877B ZA 912877 A ZA912877 A ZA 912877A ZA 912877 A ZA912877 A ZA 912877A ZA 912877 B ZA912877 B ZA 912877B
Authority
ZA
South Africa
Prior art keywords
salt
phospholipids
divalent
monovalent
divalent cationic
Prior art date
Application number
ZA912877A
Other languages
English (en)
Inventor
Paul-Alain Tremblay
Tremblay Paul-Alain
Frank Marziani
Marziani Frank
John A F Tino
A F Tino John
Frank G Pilkiewicz
G Pilkiewicz Frank
Original Assignee
Liposome Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposome Co Inc filed Critical Liposome Co Inc
Publication of ZA912877B publication Critical patent/ZA912877B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin
    • C07F9/106—Adducts, complexes, salts of phosphatides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6481—Phosphoglycerides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P9/00—Preparation of organic compounds containing a metal or atom other than H, N, C, O, S or halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fodder In General (AREA)
ZA912877A 1990-04-17 1991-04-17 Enzymatic synthesis of soluble phosphatides from phospholipids ZA912877B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51328590A 1990-04-17 1990-04-17

Publications (1)

Publication Number Publication Date
ZA912877B true ZA912877B (en) 1992-12-30

Family

ID=24042616

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA912877A ZA912877B (en) 1990-04-17 1991-04-17 Enzymatic synthesis of soluble phosphatides from phospholipids

Country Status (15)

Country Link
EP (2) EP0528834B1 (fr)
JP (1) JP3169132B2 (fr)
AT (2) ATE181747T1 (fr)
AU (1) AU646458B2 (fr)
CA (1) CA2080907C (fr)
DE (2) DE69123145T2 (fr)
DK (2) DK0727491T3 (fr)
ES (2) ES2132780T3 (fr)
GR (2) GR3022375T3 (fr)
HU (1) HU212928B (fr)
IE (1) IE911264A1 (fr)
NZ (1) NZ237845A (fr)
PT (1) PT97391B (fr)
WO (1) WO1991016444A1 (fr)
ZA (1) ZA912877B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6309623B1 (en) 1997-09-29 2001-10-30 Inhale Therapeutic Systems, Inc. Stabilized preparations for use in metered dose inhalers
US7871598B1 (en) * 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
PT1280520E (pt) 2000-05-10 2014-12-16 Novartis Ag Pós à base de fosfolípidos para administração de fármacos
DE10142014B4 (de) * 2001-08-28 2004-11-11 Degussa Bioactives Deutschland Gmbh & Co. Kg Verfahren zur Herstellung von Phosphatidylserin
PT1458360E (pt) 2001-12-19 2011-07-13 Novartis Ag Derivados de indole como agonistas do recetor s1p1
US6878532B1 (en) 2003-04-28 2005-04-12 Sioux Biochemical, Inc. Method of producing phosphatidylserine

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1900959A1 (de) * 1969-01-09 1970-08-27 Unilever Nv Verfahren zur Herstellung von Pflanzenphosphatiden mit universeller Emulgierkraft
US4235792A (en) * 1977-04-14 1980-11-25 The Governing Council Of The University Of Toronto Immunological materials
SU831129A1 (ru) * 1979-07-24 1981-05-23 Дальневосточный Государственный Уни-Верситет Способ получени фосфатидилглицерина
US4485045A (en) * 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
US4587055A (en) * 1982-05-26 1986-05-06 Research Corporation Polymerized vesicles and compounds for their preparation
DE3476770D1 (en) * 1983-04-11 1989-03-23 Meito Sangyo Kk Production of primary or secondary alcohol derivatives of phospholipids by the enzymatic technique
JPS62205788A (ja) * 1986-03-05 1987-09-10 Shoichi Shimizu ホスフアチジルグリセロ−ル又はその誘導体の製造法
WO1989001524A1 (fr) * 1987-08-14 1989-02-23 Liposome Technology, Inc. Procede de preparation de phosphatidylglycerol
US4997761A (en) * 1987-10-06 1991-03-05 Houston Biotechnology Incorporated Phosphatidyl treatment of viral disease
ES2063194T3 (es) * 1989-05-26 1995-01-01 Kao Corp Procedimiento de produccion de acido fosfatidico.

Also Published As

Publication number Publication date
PT97391B (pt) 1999-04-30
IE911264A1 (en) 1991-10-23
EP0727491B1 (fr) 1999-06-30
DK0727491T3 (da) 1999-11-22
EP0528834A4 (en) 1993-06-02
JPH05509222A (ja) 1993-12-22
ES2132780T3 (es) 1999-08-16
ATE181747T1 (de) 1999-07-15
DE69123145T2 (de) 1997-06-12
NZ237845A (en) 1993-06-25
DE69131404D1 (de) 1999-08-05
EP0528834A1 (fr) 1993-03-03
EP0528834B1 (fr) 1996-11-13
ATE145244T1 (de) 1996-11-15
WO1991016444A1 (fr) 1991-10-31
HU9203258D0 (en) 1993-01-28
CA2080907C (fr) 2001-08-14
EP0727491A1 (fr) 1996-08-21
JP3169132B2 (ja) 2001-05-21
DE69123145D1 (en) 1996-12-19
AU7699591A (en) 1991-11-11
HU212928B (en) 1996-12-30
GR3031059T3 (en) 1999-12-31
GR3022375T3 (en) 1997-04-30
DK0528834T3 (da) 1997-04-07
HUT63198A (en) 1993-07-28
PT97391A (pt) 1991-12-31
AU646458B2 (en) 1994-02-24
ES2094811T3 (es) 1997-02-01
CA2080907A1 (fr) 1991-10-18
DE69131404T2 (de) 1999-11-25

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