ZA914323B - Benzoic acid derivatives for treating leukotriene-related diseases - Google Patents

Benzoic acid derivatives for treating leukotriene-related diseases

Info

Publication number
ZA914323B
ZA914323B ZA914323A ZA914323A ZA914323B ZA 914323 B ZA914323 B ZA 914323B ZA 914323 A ZA914323 A ZA 914323A ZA 914323 A ZA914323 A ZA 914323A ZA 914323 B ZA914323 B ZA 914323B
Authority
ZA
South Africa
Prior art keywords
benzoic acid
acid derivatives
related diseases
treating leukotriene
leukotriene
Prior art date
Application number
ZA914323A
Other languages
English (en)
Inventor
Robert A Daines
A Daines Robert
William Dennis Kingsbury
Dennis Kingsbury William
Israil Nmi Pendrak
Nmi Pendrak Israil
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA914323B publication Critical patent/ZA914323B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/64One oxygen atom attached in position 2 or 6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA914323A 1990-06-07 1991-06-06 Benzoic acid derivatives for treating leukotriene-related diseases ZA914323B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53438890A 1990-06-07 1990-06-07

Publications (1)

Publication Number Publication Date
ZA914323B true ZA914323B (en) 1992-06-24

Family

ID=24129833

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA914323A ZA914323B (en) 1990-06-07 1991-06-06 Benzoic acid derivatives for treating leukotriene-related diseases

Country Status (16)

Country Link
EP (1) EP0532550A1 (de)
JP (1) JPH05507475A (de)
KR (1) KR930700445A (de)
CN (1) CN1058016A (de)
AU (1) AU7901791A (de)
CA (1) CA2083958A1 (de)
FI (1) FI925544A0 (de)
HU (1) HUT64748A (de)
IE (2) IE911912A1 (de)
IL (1) IL98388A0 (de)
MA (1) MA22196A1 (de)
MX (1) MX26142A (de)
PL (1) PL290586A1 (de)
PT (1) PT97912A (de)
WO (1) WO1991018880A1 (de)
ZA (1) ZA914323B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4226493A (en) * 1992-05-01 1993-11-29 Smithkline Beecham Corporation Leukotriene antagonists
IL106156A0 (en) * 1992-06-30 1993-10-20 Smithkline Beecham Corp Pyridinyl compounds
EP0649408A4 (de) 1992-06-30 1995-06-21 Smithkline Beecham Corp Verfahren zum herstellung von phenylthiomethylpyridinylalkenoaten.
EP0675718A1 (de) * 1992-12-23 1995-10-11 Smithkline Beecham Corporation Substitiuerte pyridinverbindungen, die als leukotrienantagonisten verwendbar sind
JPH09506367A (ja) * 1993-12-08 1997-06-24 スミスクライン・ビーチャム・コーポレイション 化合物
WO1995028386A1 (en) * 1994-04-13 1995-10-26 F. Hoffmann-La Roche Ag Substituted pyridine leukotriene b4 antagonists
JP4170765B2 (ja) * 2001-03-27 2008-10-22 明治製菓株式会社 膨化スナックの製造方法及びその製造装置
EP1660094A4 (de) 2003-08-26 2009-09-16 Univ Colorado Hemmer der serinprotease-aktivität und ihre verwendung bei verfahren und zusammensetzungen zur behandlung von bakterieninfektionen
US8093253B2 (en) 2008-03-06 2012-01-10 Hoffmann-La Roche Inc. Leukotriene B4 inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4563446A (en) * 1983-07-27 1986-01-07 Takeda Chemical Industries, Ltd. Thromboxane synthetase inhibiting 3-(1-alkenyl) pyridines
GB8505285D0 (en) * 1985-03-01 1985-04-03 Beecham Group Plc Compounds

Also Published As

Publication number Publication date
HU9203866D0 (en) 1993-03-29
IE911912A1 (en) 1991-12-18
FI925544L (fi) 1992-12-07
MA22196A1 (fr) 1992-04-01
AU7901791A (en) 1991-12-31
WO1991018880A1 (en) 1991-12-12
CN1058016A (zh) 1992-01-22
KR930700445A (ko) 1993-03-15
CA2083958A1 (en) 1991-12-08
FI925544A7 (fi) 1992-12-07
PT97912A (pt) 1992-03-31
IL98388A0 (en) 1992-07-15
HUT64748A (en) 1994-02-28
MX26142A (es) 1994-02-28
EP0532550A1 (de) 1993-03-24
JPH05507475A (ja) 1993-10-28
PL290586A1 (en) 1992-04-06
FI925544A0 (fi) 1992-12-07
IE911913A1 (en) 1991-12-18

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