ZA914323B - Benzoic acid derivatives for treating leukotriene-related diseases - Google Patents

Benzoic acid derivatives for treating leukotriene-related diseases

Info

Publication number
ZA914323B
ZA914323B ZA914323A ZA914323A ZA914323B ZA 914323 B ZA914323 B ZA 914323B ZA 914323 A ZA914323 A ZA 914323A ZA 914323 A ZA914323 A ZA 914323A ZA 914323 B ZA914323 B ZA 914323B
Authority
ZA
South Africa
Prior art keywords
benzoic acid
acid derivatives
related diseases
treating leukotriene
leukotriene
Prior art date
Application number
ZA914323A
Other languages
English (en)
Inventor
Robert A Daines
A Daines Robert
William Dennis Kingsbury
Dennis Kingsbury William
Israil Nmi Pendrak
Nmi Pendrak Israil
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA914323B publication Critical patent/ZA914323B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA914323A 1990-06-07 1991-06-06 Benzoic acid derivatives for treating leukotriene-related diseases ZA914323B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53438890A 1990-06-07 1990-06-07

Publications (1)

Publication Number Publication Date
ZA914323B true ZA914323B (en) 1992-06-24

Family

ID=24129833

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA914323A ZA914323B (en) 1990-06-07 1991-06-06 Benzoic acid derivatives for treating leukotriene-related diseases

Country Status (16)

Country Link
EP (1) EP0532550A1 (fr)
JP (1) JPH05507475A (fr)
KR (1) KR930700445A (fr)
CN (1) CN1058016A (fr)
AU (1) AU7901791A (fr)
CA (1) CA2083958A1 (fr)
FI (1) FI925544L (fr)
HU (1) HUT64748A (fr)
IE (2) IE911913A1 (fr)
IL (1) IL98388A0 (fr)
MA (1) MA22196A1 (fr)
MX (1) MX26142A (fr)
PL (1) PL290586A1 (fr)
PT (1) PT97912A (fr)
WO (1) WO1991018880A1 (fr)
ZA (1) ZA914323B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022285A1 (fr) * 1992-05-01 1993-11-11 Smithkline Beecham Corporation Antagonistes de leucotrienes
IL106156A0 (en) * 1992-06-30 1993-10-20 Smithkline Beecham Corp Pyridinyl compounds
EP0649408A4 (fr) 1992-06-30 1995-06-21 Smithkline Beecham Corp Procede de production de phenylthiomethylpyridinylalcenoates.
EP0675718A1 (fr) * 1992-12-23 1995-10-11 Smithkline Beecham Corporation Composes de pyridyle a substitution utiles comme antagonistes des leucotrienes
EP0733044A4 (fr) * 1993-12-08 1997-03-05 Smithkline Beecham Corp Composes
WO1995028386A1 (fr) * 1994-04-13 1995-10-26 F. Hoffmann-La Roche Ag Antagonistes des leucotrienes b4 a substitution pyridine
CN100456944C (zh) * 2001-03-27 2009-02-04 明治制果株式会社 膨化小食品的制造方法及其制造装置
DK2520654T3 (en) 2003-08-26 2017-05-01 Univ Colorado Regents Inhibitors of serine protease activity and their use in methods and compositions for the treatment of bacterial infections
US8093253B2 (en) 2008-03-06 2012-01-10 Hoffmann-La Roche Inc. Leukotriene B4 inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4563446A (en) * 1983-07-27 1986-01-07 Takeda Chemical Industries, Ltd. Thromboxane synthetase inhibiting 3-(1-alkenyl) pyridines
GB8505285D0 (en) * 1985-03-01 1985-04-03 Beecham Group Plc Compounds

Also Published As

Publication number Publication date
AU7901791A (en) 1991-12-31
HUT64748A (en) 1994-02-28
HU9203866D0 (en) 1993-03-29
JPH05507475A (ja) 1993-10-28
WO1991018880A1 (fr) 1991-12-12
KR930700445A (ko) 1993-03-15
MA22196A1 (fr) 1992-04-01
FI925544A0 (fi) 1992-12-07
PL290586A1 (en) 1992-04-06
PT97912A (pt) 1992-03-31
IL98388A0 (en) 1992-07-15
CA2083958A1 (fr) 1991-12-08
FI925544A7 (fi) 1992-12-07
IE911912A1 (en) 1991-12-18
FI925544L (fi) 1992-12-07
EP0532550A1 (fr) 1993-03-24
MX26142A (es) 1994-02-28
IE911913A1 (en) 1991-12-18
CN1058016A (zh) 1992-01-22

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