AU7901791A - Benzoic acid derivatives for treating leukotriene-related diseases - Google Patents

Benzoic acid derivatives for treating leukotriene-related diseases

Info

Publication number
AU7901791A
AU7901791A AU79017/91A AU7901791A AU7901791A AU 7901791 A AU7901791 A AU 7901791A AU 79017/91 A AU79017/91 A AU 79017/91A AU 7901791 A AU7901791 A AU 7901791A AU 7901791 A AU7901791 A AU 7901791A
Authority
AU
Australia
Prior art keywords
compound
aliphatic
aryl
alkyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU79017/91A
Other languages
English (en)
Inventor
Robert A Daines
William Dennis Kingsbury
Israil Pendrak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of AU7901791A publication Critical patent/AU7901791A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU79017/91A 1990-06-07 1991-05-15 Benzoic acid derivatives for treating leukotriene-related diseases Abandoned AU7901791A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53438890A 1990-06-07 1990-06-07
US534388 1990-06-07

Publications (1)

Publication Number Publication Date
AU7901791A true AU7901791A (en) 1991-12-31

Family

ID=24129833

Family Applications (1)

Application Number Title Priority Date Filing Date
AU79017/91A Abandoned AU7901791A (en) 1990-06-07 1991-05-15 Benzoic acid derivatives for treating leukotriene-related diseases

Country Status (16)

Country Link
EP (1) EP0532550A1 (fr)
JP (1) JPH05507475A (fr)
KR (1) KR930700445A (fr)
CN (1) CN1058016A (fr)
AU (1) AU7901791A (fr)
CA (1) CA2083958A1 (fr)
FI (1) FI925544L (fr)
HU (1) HUT64748A (fr)
IE (2) IE911913A1 (fr)
IL (1) IL98388A0 (fr)
MA (1) MA22196A1 (fr)
MX (1) MX26142A (fr)
PL (1) PL290586A1 (fr)
PT (1) PT97912A (fr)
WO (1) WO1991018880A1 (fr)
ZA (1) ZA914323B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022285A1 (fr) * 1992-05-01 1993-11-11 Smithkline Beecham Corporation Antagonistes de leucotrienes
MA22926A1 (fr) * 1992-06-30 1994-04-01 Smithkline Beecham Corp Procede pour la preparation de nouveaux composes.
NZ254473A (en) 1992-06-30 1996-11-26 Smithkline Beecham Corp Preparation of phenylthiomethylpyridinylalkenoates
JPH08505148A (ja) * 1992-12-23 1996-06-04 スミスクライン・ビーチャム・コーポレイション ロイコトリエンアンタゴニストとして有用な置換ピリジル化合物
AU1335795A (en) * 1993-12-08 1995-06-27 Smithkline Beecham Corporation Compounds
JP2866202B2 (ja) * 1994-04-13 1999-03-08 エフ・ホフマン−ラ ロシュ アーゲー 置換ピリジンロイコトリエンb▲下4▼拮抗物質
CN100456944C (zh) * 2001-03-27 2009-02-04 明治制果株式会社 膨化小食品的制造方法及其制造装置
PL2520654T3 (pl) 2003-08-26 2017-08-31 The Regents Of The University Of Colorado, A Body Corporate Inhibitory aktywności proteazy serynowej i ich zastosowanie w sposobach i kompozycjach do leczenia zakażeń bakteryjnych
US8093253B2 (en) 2008-03-06 2012-01-10 Hoffmann-La Roche Inc. Leukotriene B4 inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4563446A (en) * 1983-07-27 1986-01-07 Takeda Chemical Industries, Ltd. Thromboxane synthetase inhibiting 3-(1-alkenyl) pyridines
GB8505285D0 (en) * 1985-03-01 1985-04-03 Beecham Group Plc Compounds

Also Published As

Publication number Publication date
HUT64748A (en) 1994-02-28
WO1991018880A1 (fr) 1991-12-12
PT97912A (pt) 1992-03-31
HU9203866D0 (en) 1993-03-29
FI925544A7 (fi) 1992-12-07
FI925544A0 (fi) 1992-12-07
MX26142A (es) 1994-02-28
IE911913A1 (en) 1991-12-18
CN1058016A (zh) 1992-01-22
MA22196A1 (fr) 1992-04-01
IE911912A1 (en) 1991-12-18
KR930700445A (ko) 1993-03-15
EP0532550A1 (fr) 1993-03-24
FI925544L (fi) 1992-12-07
PL290586A1 (en) 1992-04-06
CA2083958A1 (fr) 1991-12-08
JPH05507475A (ja) 1993-10-28
IL98388A0 (en) 1992-07-15
ZA914323B (en) 1992-06-24

Similar Documents

Publication Publication Date Title
JP2000510481A (ja) ニコチンアミド誘導体
US20090170903A1 (en) Ester derivatives as phosphodiesterase inhibitors
AP333A (en) Phenyl-substituted pyridyl aliphatic compounds for treating leukotriene-related diseases.
WO1991018880A1 (fr) Derives d'acide benzoique utilises dans le traitement de maladies associees au leucotriene
AU655428B2 (en) Benzoic acid derivatives
EP0649412B1 (fr) Composes pharmaceutiques a base de pyridine
WO1991018879A1 (fr) Derives d'acide phtalamique utilises dans le traitement de maladies associees aux leucotrienes
WO1991018883A1 (fr) Derives d'acide pyridyle-benzoique a liaison amide utilises dans le traitement de maladies associees aux leucotrienes
US5656636A (en) Pyridine compounds for treating leukotriene-related diseases
WO1993022285A1 (fr) Antagonistes de leucotrienes
EP0639975A1 (fr) Composes de pyridine heterocyclique substituee et leurs utilisations
EP0733044A1 (fr) Composes
WO1993011768A1 (fr) Composes a base de pyridyle destines au traitement du psoriasis
EP0675718A1 (fr) Composes de pyridyle a substitution utiles comme antagonistes des leucotrienes