ZA918335B - Method for the preparation of 5,11-dihydro-6h-dipyrido(3,2-b:2',3'-e)(1,4)diazepines - Google Patents

Method for the preparation of 5,11-dihydro-6h-dipyrido(3,2-b:2',3'-e)(1,4)diazepines

Info

Publication number
ZA918335B
ZA918335B ZA918335A ZA918335A ZA918335B ZA 918335 B ZA918335 B ZA 918335B ZA 918335 A ZA918335 A ZA 918335A ZA 918335 A ZA918335 A ZA 918335A ZA 918335 B ZA918335 B ZA 918335B
Authority
ZA
South Africa
Prior art keywords
dipyrido
diazepines
dihydro
preparation
Prior art date
Application number
ZA918335A
Other languages
English (en)
Inventor
Karl G Grozinger
G Grozinger Karl
Karl D Hargrave
D Hargrave Karl
Julian Adams
Adams Julian
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of ZA918335B publication Critical patent/ZA918335B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA918335A 1990-10-19 1991-10-18 Method for the preparation of 5,11-dihydro-6h-dipyrido(3,2-b:2',3'-e)(1,4)diazepines ZA918335B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US60045190A 1990-10-19 1990-10-19

Publications (1)

Publication Number Publication Date
ZA918335B true ZA918335B (en) 1992-09-30

Family

ID=24403650

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA918335A ZA918335B (en) 1990-10-19 1991-10-18 Method for the preparation of 5,11-dihydro-6h-dipyrido(3,2-b:2',3'-e)(1,4)diazepines

Country Status (14)

Country Link
EP (1) EP0482481A1 (fr)
JP (1) JPH05163272A (fr)
KR (1) KR920008041A (fr)
CA (1) CA2052946A1 (fr)
CS (1) CS312691A3 (fr)
FI (1) FI914923A7 (fr)
HU (1) HU210678B (fr)
IE (1) IE913662A1 (fr)
NO (1) NO914102L (fr)
NZ (1) NZ240279A (fr)
PL (1) PL292097A1 (fr)
PT (1) PT99273A (fr)
YU (1) YU165891A (fr)
ZA (1) ZA918335B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992022531A1 (fr) * 1991-06-11 1992-12-23 Boehringer Ingelheim Pharmaceuticals, Inc. Procede de preparation de 3-amino-2-chloro-4-alkylpyridines
US5200522A (en) * 1991-06-11 1993-04-06 Boehringer Ingelheim Pharmaceuticals, Inc. Method for preparing 3-amino-2-chloro-4-alkylpyridines
DE4403311C1 (de) * 1994-02-03 1995-04-20 Boehringer Ingelheim Kg Verfahren zur Herstellung von Nevirapine (11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4-diazepin]-6-on)
CN113149896A (zh) * 2021-03-09 2021-07-23 利尔化学股份有限公司 一种3-氨基吡啶的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2424811C3 (de) * 1974-05-22 1981-08-20 Dr. Karl Thomae Gmbh, 7950 Biberach Pyrido-benzodiazepinone, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
IT1194766B (it) * 1981-03-10 1988-09-28 Crc Ricerca Chim Processo per la preparazione di 11-(2'-sostituito)-acetil-5,11-diidro-6h-pirido-(2,3-b)(1,4)-benzodiazepin-6-oni
DE3122670A1 (de) * 1981-06-06 1982-12-23 Dr. Karl Thomae Gmbh, 7950 Biberach "neue 1,4,9,10-tetrahydro-pyrazolo(4,3-e) pyrido(3,2-b)(1,4)diazepin-10-one, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von pharmazeutischen wirkstoffen"
DE3222809A1 (de) * 1981-07-15 1983-02-03 Dr. Karl Thomae Gmbh, 7950 Biberach Verfahren zur herstellung von 5,11-dihydro-6h-pyrido(2,3-b)-(1,4) benzodiazepin-6-onen
DK0393529T3 (da) * 1989-04-20 1993-11-15 Boehringer Ingelheim Pharma 5,11-Dihydro-6H-dipyrido(3,2-b:2,3-e)(1,4)diazepin-6-oner og deres anvendelse ved forhindring eller behandling af AIDS
EP0410148B1 (fr) * 1989-06-28 1994-04-06 Boehringer Ingelheim Pharmaceuticals Inc. 5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazépin-6-ones et -thiones et leur utilisation pour la prévention ou le traitement du SIDA

Also Published As

Publication number Publication date
NO914102L (no) 1992-04-21
FI914923A0 (fi) 1991-10-18
JPH05163272A (ja) 1993-06-29
CA2052946A1 (fr) 1992-04-20
AU8592491A (en) 1992-04-30
KR920008041A (ko) 1992-05-27
EP0482481A1 (fr) 1992-04-29
CS312691A3 (en) 1992-05-13
HU210678B (en) 1995-06-28
HUT59408A (en) 1992-05-28
FI914923L (fi) 1992-04-20
FI914923A7 (fi) 1992-04-20
PT99273A (pt) 1992-08-31
YU165891A (sh) 1994-06-10
NZ240279A (en) 1993-12-23
AU646096B2 (en) 1994-02-10
IE913662A1 (en) 1992-04-22
PL292097A1 (en) 1992-07-13
NO914102D0 (no) 1991-10-18
HU913296D0 (en) 1992-01-28

Similar Documents

Publication Publication Date Title
FI905674A0 (fi) Menetelmä valmistaa farmaseuttisesti käyttökelpoisia 5,11-dihydro-6H-dipyrido/3,2-b:2',3'-e//1,4/diatsepin-6-oneja ja -tioneja
FI92828C (fi) Menetelmä valmistaa terapeuttisesti arvokasta 5,11-dihydro-6H-dipyrido/3,2-b:2',3'-e/ /1,4/diatsepin-6-onia
PH30110A (en) 4,5-Dihydro-4-oxo-pyrrolo-¬1,2-a¾¬quinoxalinones¾ and corresponding aza analogs and process for their preparation
GB2244056B (en) Preparation of non-racemic furo[3,4-c]pyridine derivatives
HUP9602054A2 (en) Benzofuro- and benzothieno[3,2-b]pyridine derivatives, pharmaceutical compositions containing them, and process for the preparation thereof
ZA918335B (en) Method for the preparation of 5,11-dihydro-6h-dipyrido(3,2-b:2',3'-e)(1,4)diazepines
IL92465A0 (en) Process for the preparation of 4,4'-dibromodiphenylether
EP0474016A3 (en) Method for the preparation of 2,3-dihydro-benzofuranes
AU646096C (en) Method for the preparation of 5,11-dihydro-6H-dipyrido (3,2-b:2',3'-e)(1,4)diazepines
CS390991A3 (en) Thiadiazinone derivatives, process of their preparation andpharmaceuticals based thereon
HU913371D0 (en) Substituted tieno(3,2-b)pyran-5,7-diones
IL96282A0 (en) Method for the preparation of 5-chlorcarbonyl-5h-dibenz-/b,f/-azepin
ZA929419B (en) Process for the preparation of trifluorobenzene derivatives.
HUT59407A (en) Process for producing 5,11-dihydro-6h-dipydro/3,2-b : 2',3'-e/ /1,4/ diazepines and pharmaceutical compositions comprising same
HU907186D0 (en) Process for producing 5,11-dihydro-6h-dipyrido (3,2-b:2',3'-e) (1,4) diazepines and pharmaceutical preparatives containing these compounds
GR3020992T3 (en) Method for the preparation of aminotriazin derivatives
LTIP578A (en) Method for the preparation of acylaminobenzamides derivatives
GB2251621B (en) Process for the preparation of pyrethroid derivatives
IL112575A (en) 4-Substituted 2-methyl-10h-thieno [2,3-b][1,5]benzodiazepine
IL98913A0 (en) Process for the preparation of 6-(3-substituted aminopropionyl)7-deacetylforskolin derivatives
EP0381040A3 (en) Method for the preparation of 2,2-dialkylpropionaldehydes
SG125793G (en) Preparation of non-racemic furo (3,4-c) pyridine derivatives
CS19290A2 (en) Method of 2,3-diarylquinoxalines preparation
HU9204124D0 (en) 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethyl-pyrrholo/2,3-b/-indole-tetrahydro-isoquinoline-urea derivatives
IL93687A0 (en) Process for the preparation of 4,4'-dihydroxy-3-methyl-diphenylether