ZA919435B - Use of xanthines for the preparation of a medicament effective for inhibiting the effects of allograft reaction in humans - Google Patents
Use of xanthines for the preparation of a medicament effective for inhibiting the effects of allograft reaction in humansInfo
- Publication number
- ZA919435B ZA919435B ZA919435A ZA919435A ZA919435B ZA 919435 B ZA919435 B ZA 919435B ZA 919435 A ZA919435 A ZA 919435A ZA 919435 A ZA919435 A ZA 919435A ZA 919435 B ZA919435 B ZA 919435B
- Authority
- ZA
- South Africa
- Prior art keywords
- xanthines
- humans
- inhibiting
- preparation
- effects
- Prior art date
Links
- LRFVTYWOQMYALW-UHFFFAOYSA-N 9H-xanthine Chemical class O=C1NC(=O)NC2=C1NC=N2 LRFVTYWOQMYALW-UHFFFAOYSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 230000000694 effects Effects 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
- 229940065721 systemic for obstructive airway disease xanthines Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Transplantation (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62047990A | 1990-11-30 | 1990-11-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA919435B true ZA919435B (en) | 1992-08-26 |
Family
ID=24486117
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA919435A ZA919435B (en) | 1990-11-30 | 1991-11-29 | Use of xanthines for the preparation of a medicament effective for inhibiting the effects of allograft reaction in humans |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0493682A3 (de) |
| JP (1) | JPH0525048A (de) |
| KR (1) | KR920009398A (de) |
| AU (1) | AU8824791A (de) |
| CA (1) | CA2056800A1 (de) |
| HU (1) | HUT59603A (de) |
| IE (1) | IE914162A1 (de) |
| IL (1) | IL100194A0 (de) |
| PT (1) | PT99650A (de) |
| ZA (1) | ZA919435B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1992021344A2 (en) * | 1991-05-24 | 1992-12-10 | Fred Hutchinson Cancer Research Center | Modulation of cellular response to external stimuli |
| DE4430127A1 (de) * | 1994-08-25 | 1996-03-14 | Hoechst Ag | Kombinationspräparat, enthaltend Cyclosporin A oder FK506 und ein Xanthinderivat |
| DE4430128A1 (de) * | 1994-08-25 | 1996-02-29 | Hoechst Ag | Kombinationspräparat mit immunsuppressiven, kardiovaskulären und cerebralen Wirkungen |
| US6323201B1 (en) | 1994-12-29 | 2001-11-27 | The Regents Of The University Of California | Compounds for inhibition of ceramide-mediated signal transduction |
| US6930101B1 (en) | 1999-05-17 | 2005-08-16 | The Regents Of The University Of California | Thiazolopyrimidines useful as TNFα inhibitors |
| KR20030007244A (ko) * | 2002-10-04 | 2003-01-23 | 주식회사 코티티정보통신 | 온/오프 후크 스위치가 장착된 핸드셋을 가진 전화기 |
| KR20100121527A (ko) | 2008-02-29 | 2010-11-17 | 콘서트 파마슈티컬즈, 인크. | 치환된 잔틴 유도체 |
| US20110053961A1 (en) | 2009-02-27 | 2011-03-03 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
| MX2012002704A (es) | 2009-09-02 | 2012-03-21 | Concert Pharmaceuticals Inc | Derivados de xantina sustituidos. |
| EP2611807A2 (de) | 2010-09-01 | 2013-07-10 | Concert Pharmaceuticals Inc. | Polymorphe aus (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3-7-dimethyl-1h-purin-2,6(3h,7h)dion |
| WO2013013052A1 (en) | 2011-07-19 | 2013-01-24 | Concert Pharmaceuticals, Inc. | Substituted xanthine derivatives |
| IN2014DN08443A (de) | 2012-04-13 | 2015-05-08 | Concert Pharmaceuticals Inc | |
| WO2013159006A1 (en) | 2012-04-20 | 2013-10-24 | Concert Pharmaceuticals, Inc. | Polymorphs of (s)-1-(4,4,6,6,6-pentadeutero-5-hydroxyhexyl)-3,7-dimethyl-1h-purine-2,6(3h,7h)-dione |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0063827B1 (de) * | 1980-05-02 | 1985-08-14 | Societe Des Produits Nestle S.A. | 1-Isopropyl- und 1-Isobutyl-3,7-dimethylxanthin als Arzneimittel |
| US4965271A (en) * | 1986-12-31 | 1990-10-23 | Hoechst Roussel Pharmaceuticals, Inc. | Method of inhibiting the activity of leukocyte derived cytokines |
| IL100535A (en) * | 1986-12-31 | 1994-05-30 | Hoechst Roussel Pharma | Pharmaceutical preparations containing a history of xanthine to relieve disease states |
| DE3817955A1 (de) * | 1988-05-27 | 1989-11-30 | Hoechst Ag | Tnf-inhibitor enthaltendes arzneimittel |
-
1991
- 1991-11-28 EP EP19910120426 patent/EP0493682A3/en not_active Withdrawn
- 1991-11-28 IL IL100194A patent/IL100194A0/xx unknown
- 1991-11-29 HU HU913722A patent/HUT59603A/hu unknown
- 1991-11-29 JP JP3316209A patent/JPH0525048A/ja active Pending
- 1991-11-29 CA CA002056800A patent/CA2056800A1/en not_active Abandoned
- 1991-11-29 PT PT99650A patent/PT99650A/pt not_active Application Discontinuation
- 1991-11-29 KR KR1019910021767A patent/KR920009398A/ko not_active Withdrawn
- 1991-11-29 IE IE416291A patent/IE914162A1/en not_active Application Discontinuation
- 1991-11-29 AU AU88247/91A patent/AU8824791A/en not_active Abandoned
- 1991-11-29 ZA ZA919435A patent/ZA919435B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT59603A (en) | 1992-06-29 |
| HU913722D0 (en) | 1992-02-28 |
| JPH0525048A (ja) | 1993-02-02 |
| CA2056800A1 (en) | 1992-05-31 |
| IE914162A1 (en) | 1992-06-03 |
| IL100194A0 (en) | 1992-08-18 |
| EP0493682A3 (en) | 1992-11-19 |
| AU8824791A (en) | 1992-06-04 |
| KR920009398A (ko) | 1992-06-25 |
| PT99650A (pt) | 1992-11-30 |
| EP0493682A2 (de) | 1992-07-08 |
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