ZA921232B - Quinoline-containing ketoacids as leukotriene antagonists - Google Patents
Quinoline-containing ketoacids as leukotriene antagonistsInfo
- Publication number
- ZA921232B ZA921232B ZA921232A ZA921232A ZA921232B ZA 921232 B ZA921232 B ZA 921232B ZA 921232 A ZA921232 A ZA 921232A ZA 921232 A ZA921232 A ZA 921232A ZA 921232 B ZA921232 B ZA 921232B
- Authority
- ZA
- South Africa
- Prior art keywords
- ketoacids
- quinoline
- leukotriene antagonists
- compounds
- useful
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Transplantation (AREA)
- Urology & Nephrology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65893191A | 1991-02-21 | 1991-02-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA921232B true ZA921232B (en) | 1992-10-28 |
Family
ID=24643302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA921232A ZA921232B (en) | 1991-02-21 | 1992-02-20 | Quinoline-containing ketoacids as leukotriene antagonists |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0500360B1 (fr) |
| JP (1) | JPH0788361B2 (fr) |
| KR (1) | KR920016423A (fr) |
| CN (1) | CN1065062A (fr) |
| AT (1) | ATE154801T1 (fr) |
| AU (1) | AU648385B2 (fr) |
| CA (1) | CA2061675C (fr) |
| CS (1) | CS47192A3 (fr) |
| DE (1) | DE69220517T2 (fr) |
| ES (1) | ES2104821T3 (fr) |
| FI (1) | FI920734L (fr) |
| HU (1) | HU9200552D0 (fr) |
| IE (1) | IE920499A1 (fr) |
| IL (1) | IL100985A0 (fr) |
| MX (1) | MX9200714A (fr) |
| NO (1) | NO920681L (fr) |
| ZA (1) | ZA921232B (fr) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5270324A (en) * | 1992-04-10 | 1993-12-14 | Merck Frosst Canada, Inc. | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists |
| GB9216768D0 (en) * | 1992-08-07 | 1992-09-23 | Leo Pharm Prod Ltd | Chemical compounds |
| KR19990008148A (ko) * | 1995-04-28 | 1999-01-25 | 다께다 구니오 | 관절염 치료 조성물 |
| AU3868497A (en) * | 1996-08-26 | 1998-03-19 | Yamanouchi Pharmaceutical Co., Ltd. | Benzenesulfone compounds and salts thereof |
| DE69900207T2 (de) * | 1998-07-14 | 2001-11-22 | Alcon Laboratories, Inc. | Verwendung von 11-(3-dimethylaminopropyliden)-6,11-dihydrodibenz[b,e]oxepin-2-essigsäure und deren pharmazeutisch annehmbaren salzen zur herstellung eines medikaments zur behandlung nicht-allergisch-bedingten augenentzündungen und zur prevention der okularen neovaskularisation |
| US7547787B2 (en) | 2004-04-21 | 2009-06-16 | Teva Pharmaceutical Industries Ltd. | Processes for preparing montelukast sodium |
| ITMI20050247A1 (it) * | 2005-02-18 | 2006-08-19 | Chemi Spa | Processo per la preparazione di montelukast |
| WO2006131782A1 (fr) * | 2005-06-07 | 2006-12-14 | Glade Organics Private Limited | Procede de preparation de methyl-2-(3-(2-(7-chloro-2-quinolinyl-ethenyl)-phenyl)-3-oxopropyl)benzoate |
| EP1904448B1 (fr) | 2005-07-05 | 2011-02-02 | Teva Pharmaceutical Industries, Ltd. | Purification du montélukast |
| CN101365683A (zh) * | 2005-11-18 | 2009-02-11 | 斯索恩有限公司 | 制备孟鲁司特及其中间体的方法 |
| AR057909A1 (es) * | 2005-11-18 | 2007-12-26 | Synthon Bv | Proceso para preparar montelukast y compuestos relacionados, que utiliza un compuesto intermediario derivado de un ester sulfonico. |
| KR20090080038A (ko) * | 2006-09-15 | 2009-07-23 | 씨아이피엘에이 엘티디. | 몬테루카스트의 제조방법 및 그의 중간체 |
| ES2320077B1 (es) | 2007-07-31 | 2010-02-26 | Moehs Iberica, S.L. | Proceso de preparacion de un antagonista de leucotrienos y de un intermedio del mismo. |
| CN101851196B (zh) * | 2010-05-28 | 2011-07-27 | 中国科学院昆明植物研究所 | 2-(1h)喹啉酮衍生物,其药物组合物及其制备方法和用途 |
| KR20140108627A (ko) * | 2011-07-26 | 2014-09-12 | 썬 파마 어드밴스트 리서치 컴패니 리미티드 | 퀴놀린-, 퀸옥살린 또는 벤조티아졸계 시스테이닐 류코트리엔 길항물질 (ltc4) |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE59889B1 (en) * | 1986-02-14 | 1994-04-20 | Merck Frosst Canada Inc | 2-substituted quinoline dioic acids |
| EP0318093A3 (fr) * | 1987-11-25 | 1990-12-05 | Merck Frosst Canada Inc. | Acides dicarboxyliques des diaryl quinoléines et leur utilisation comme médicaments |
| EP0349062A1 (fr) * | 1988-06-27 | 1990-01-03 | Merck Frosst Canada Inc. | Acides quinolineétheralkanoiques |
| NZ233752A (en) * | 1989-05-24 | 1993-05-26 | Merck Frosst Canada Inc | Substituted quinoline derivatives, preparation and pharmaceutical compositions thereof |
-
1992
- 1992-02-17 IE IE049992A patent/IE920499A1/en not_active Application Discontinuation
- 1992-02-18 IL IL100985A patent/IL100985A0/xx unknown
- 1992-02-18 CS CS92471A patent/CS47192A3/cs unknown
- 1992-02-20 AT AT92301393T patent/ATE154801T1/de not_active IP Right Cessation
- 1992-02-20 HU HU9200552A patent/HU9200552D0/hu unknown
- 1992-02-20 FI FI920734A patent/FI920734L/fi not_active Application Discontinuation
- 1992-02-20 CN CN92102076A patent/CN1065062A/zh active Pending
- 1992-02-20 NO NO92920681A patent/NO920681L/no unknown
- 1992-02-20 MX MX9200714A patent/MX9200714A/es unknown
- 1992-02-20 AU AU11119/92A patent/AU648385B2/en not_active Ceased
- 1992-02-20 DE DE69220517T patent/DE69220517T2/de not_active Expired - Fee Related
- 1992-02-20 ES ES92301393T patent/ES2104821T3/es not_active Expired - Lifetime
- 1992-02-20 EP EP92301393A patent/EP0500360B1/fr not_active Expired - Lifetime
- 1992-02-20 KR KR1019920002536A patent/KR920016423A/ko not_active Withdrawn
- 1992-02-20 ZA ZA921232A patent/ZA921232B/xx unknown
- 1992-02-21 JP JP4034632A patent/JPH0788361B2/ja not_active Expired - Lifetime
- 1992-02-21 CA CA002061675A patent/CA2061675C/fr not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0525135A (ja) | 1993-02-02 |
| EP0500360B1 (fr) | 1997-06-25 |
| FI920734A7 (fi) | 1992-08-22 |
| CA2061675C (fr) | 2002-12-17 |
| DE69220517D1 (de) | 1997-07-31 |
| KR920016423A (ko) | 1992-09-24 |
| JPH0788361B2 (ja) | 1995-09-27 |
| DE69220517T2 (de) | 1997-12-18 |
| ATE154801T1 (de) | 1997-07-15 |
| MX9200714A (es) | 1992-10-01 |
| HU9200552D0 (en) | 1992-05-28 |
| CS47192A3 (en) | 1992-10-14 |
| NO920681D0 (no) | 1992-02-20 |
| CA2061675A1 (fr) | 1992-08-22 |
| CN1065062A (zh) | 1992-10-07 |
| FI920734A0 (fi) | 1992-02-20 |
| IE920499A1 (en) | 1992-08-26 |
| AU1111992A (en) | 1992-08-27 |
| ES2104821T3 (es) | 1997-10-16 |
| NO920681L (no) | 1992-08-24 |
| IL100985A0 (en) | 1992-11-15 |
| AU648385B2 (en) | 1994-04-21 |
| FI920734L (fi) | 1992-08-22 |
| EP0500360A1 (fr) | 1992-08-26 |
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