ZA921648B - Nitrogen oxides of aza-and diaza-anthracenedione derivatives as antitumor agents - Google Patents
Nitrogen oxides of aza-and diaza-anthracenedione derivatives as antitumor agentsInfo
- Publication number
- ZA921648B ZA921648B ZA921648A ZA921648A ZA921648B ZA 921648 B ZA921648 B ZA 921648B ZA 921648 A ZA921648 A ZA 921648A ZA 921648 A ZA921648 A ZA 921648A ZA 921648 B ZA921648 B ZA 921648B
- Authority
- ZA
- South Africa
- Prior art keywords
- diaza
- aza
- nitrogen oxides
- antitumor agents
- anthracenedione derivatives
- Prior art date
Links
- MWUXSHHQAYIFBG-UHFFFAOYSA-N nitrogen oxide Inorganic materials O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 title abstract 6
- MIIDWKMJIXIZPV-UHFFFAOYSA-N benzo[g]cinnoline-3,4-dione Chemical class C1=CC=C2C=C(C(C(=O)N=N3)=O)C3=CC2=C1 MIIDWKMJIXIZPV-UHFFFAOYSA-N 0.000 title abstract 2
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/08—Aza-anthracenes
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI910618A IT1244755B (it) | 1991-03-08 | 1991-03-08 | Azoto ossidi di derivati aza- e diaza-antracenedionici come farmaci antitumorali |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA921648B true ZA921648B (en) | 1992-11-25 |
Family
ID=11358951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA921648A ZA921648B (en) | 1991-03-08 | 1992-03-05 | Nitrogen oxides of aza-and diaza-anthracenedione derivatives as antitumor agents |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0639183B1 (de) |
| JP (1) | JPH06505244A (de) |
| AT (2) | ATE167856T1 (de) |
| AU (1) | AU1276892A (de) |
| DE (1) | DE69226091D1 (de) |
| IE (1) | IE920704A1 (de) |
| IL (1) | IL101157A (de) |
| IT (1) | IT1244755B (de) |
| MX (1) | MX9200919A (de) |
| NZ (1) | NZ241856A (de) |
| TW (1) | TW197426B (de) |
| WO (1) | WO1992015566A1 (de) |
| ZA (1) | ZA921648B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104557704B (zh) * | 2013-10-28 | 2017-05-10 | 北京凯莱天成医药科技有限公司 | 一种匹杉琼马来酸盐的制备方法 |
| CN103787970A (zh) * | 2014-01-14 | 2014-05-14 | 北京万全德众医药生物技术有限公司 | 一锅煮法制备6，9-二氟苯并异喹啉-5，10-二酮的工艺 |
| CN106366036B (zh) * | 2016-08-18 | 2019-07-09 | 湖北丽益医药科技有限公司 | 6,9-双[(2-氨基乙基)氨基]苯并[g]异喹啉-5,10-二酮二马来酸盐及其合成工艺 |
-
1991
- 1991-03-08 IT ITMI910618A patent/IT1244755B/it active IP Right Grant
-
1992
- 1992-02-27 AU AU12768/92A patent/AU1276892A/en not_active Abandoned
- 1992-02-27 EP EP92905365A patent/EP0639183B1/de not_active Expired - Lifetime
- 1992-02-27 JP JP4504948A patent/JPH06505244A/ja active Pending
- 1992-02-27 WO PCT/EP1992/000421 patent/WO1992015566A1/en not_active Ceased
- 1992-02-27 AT AT92905365T patent/ATE167856T1/de not_active IP Right Cessation
- 1992-02-27 DE DE69226091T patent/DE69226091D1/de not_active Expired - Lifetime
- 1992-03-02 AT AT92905252T patent/ATE123220T1/de not_active IP Right Cessation
- 1992-03-03 MX MX9200919A patent/MX9200919A/es unknown
- 1992-03-05 IL IL10115792A patent/IL101157A/en not_active IP Right Cessation
- 1992-03-05 NZ NZ241856A patent/NZ241856A/en unknown
- 1992-03-05 TW TW081101691A patent/TW197426B/zh active
- 1992-03-05 IE IE070492A patent/IE920704A1/en unknown
- 1992-03-05 ZA ZA921648A patent/ZA921648B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL101157A (en) | 1996-07-23 |
| JPH06505244A (ja) | 1994-06-16 |
| EP0639183A1 (de) | 1995-02-22 |
| IE920704A1 (en) | 1992-09-09 |
| AU1276892A (en) | 1992-10-06 |
| ATE123220T1 (de) | 1995-06-15 |
| ITMI910618A0 (it) | 1991-03-08 |
| ITMI910618A1 (it) | 1992-09-08 |
| DE69226091D1 (de) | 1998-08-06 |
| TW197426B (de) | 1993-01-01 |
| WO1992015566A1 (en) | 1992-09-17 |
| IT1244755B (it) | 1994-08-08 |
| EP0639183B1 (de) | 1998-07-01 |
| NZ241856A (en) | 1994-12-22 |
| MX9200919A (es) | 1992-09-30 |
| ATE167856T1 (de) | 1998-07-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO931635L (no) | Fremgangsmaate for fremstilling av kinazolin-derivater | |
| DE69716135D1 (en) | In 6-position durch thio substituierte paclitaxele | |
| HU9302384D0 (en) | 2,4-diamino-quinazoline derivatives and medical preparatives containing them | |
| IL127918A0 (en) | Novel amino sugar and related sugar derivatives of indolylopyrrolocarbazoles their use as antitumor agents and pharmaceutical formulations | |
| MY115211A (en) | Novel amino acid derivatives, their preparation and use | |
| IL107378A0 (en) | Soluble interferon a-receptor, its preparation and use | |
| TR200001102T2 (tr) | İkameli tetrahidropirimidinen türevleri, üretimleri ve kullanımları. | |
| ZA921648B (en) | Nitrogen oxides of aza-and diaza-anthracenedione derivatives as antitumor agents | |
| GB9509888D0 (en) | Terpenoidic derivatives useful as antitumour agents | |
| MX9700813A (es) | Nuevos derivados 3-substituidos de 3h-2,3-benzodiazepina, su preparacion y su uso como medicamentos. | |
| GR3018038T3 (en) | Antitumor amino acid and peptide derivatives of 1,4-bis[ (aminoalkyl and hydroxyaminoalkyl)- amino]-5,8 dihydroxyanthraquinones. | |
| CA2298820A1 (en) | The use of 1,3,4,6-tetrahydroxy-helianthrone and its derivatives in photodynamic therapy and certain such novel derivatives | |
| ES2105959A1 (es) | Derivados de 1,4-dioxido de quinoxalina, procedimiento de preparacion y de utilizacion. | |
| GR79958B (de) | ||
| IL131478A0 (en) | Methods for treatment of scar tissue | |
| HUP9902883A3 (en) | Bis/acridinecarboxamide/ and bis/phenazinecarboxamide/ derivatives as antitumour agents, preparation and use thereof | |
| LTIP378A (en) | Methylpiperazinoazepine derivatives, preparation and use tereof | |
| IL98117A0 (en) | 3'-deamino-4'-deoxy-4'-amino-8-fluoroanthracyclines,their preparation and pharmaceutical compositions containing them | |
| GB9723824D0 (en) | Cytostatic agents | |
| UA29639A (uk) | Протипухлинний засіб | |
| IT1255649B (it) | Peptidi dotati di attivita' antibatterica | |
| NZ239758A (en) | Oxadiazole-substituted imidazo (1,5-a) quinoxaline derivatives and pharmaceutical compositions | |
| MX9706183A (es) | Analogos de paclitaxel, preparaciones y uso como agentes antitumorales. |