IL101157A - History of aza- and diazea-anthracenedione N-oxides, process for their preparation and anigoidal preparations containing them - Google Patents

History of aza- and diazea-anthracenedione N-oxides, process for their preparation and anigoidal preparations containing them

Info

Publication number
IL101157A
IL101157A IL10115792A IL10115792A IL101157A IL 101157 A IL101157 A IL 101157A IL 10115792 A IL10115792 A IL 10115792A IL 10115792 A IL10115792 A IL 10115792A IL 101157 A IL101157 A IL 101157A
Authority
IL
Israel
Prior art keywords
formula
compounds
compound
alkyl
bis
Prior art date
Application number
IL10115792A
Other languages
English (en)
Hebrew (he)
Original Assignee
Boehringer Mannheim Italia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Italia filed Critical Boehringer Mannheim Italia
Publication of IL101157A publication Critical patent/IL101157A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/08—Aza-anthracenes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL10115792A 1991-03-08 1992-03-05 History of aza- and diazea-anthracenedione N-oxides, process for their preparation and anigoidal preparations containing them IL101157A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITMI910618A IT1244755B (it) 1991-03-08 1991-03-08 Azoto ossidi di derivati aza- e diaza-antracenedionici come farmaci antitumorali

Publications (1)

Publication Number Publication Date
IL101157A true IL101157A (en) 1996-07-23

Family

ID=11358951

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10115792A IL101157A (en) 1991-03-08 1992-03-05 History of aza- and diazea-anthracenedione N-oxides, process for their preparation and anigoidal preparations containing them

Country Status (13)

Country Link
EP (1) EP0639183B1 (de)
JP (1) JPH06505244A (de)
AT (2) ATE167856T1 (de)
AU (1) AU1276892A (de)
DE (1) DE69226091D1 (de)
IE (1) IE920704A1 (de)
IL (1) IL101157A (de)
IT (1) IT1244755B (de)
MX (1) MX9200919A (de)
NZ (1) NZ241856A (de)
TW (1) TW197426B (de)
WO (1) WO1992015566A1 (de)
ZA (1) ZA921648B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104557704B (zh) * 2013-10-28 2017-05-10 北京凯莱天成医药科技有限公司 一种匹杉琼马来酸盐的制备方法
CN103787970A (zh) * 2014-01-14 2014-05-14 北京万全德众医药生物技术有限公司 一锅煮法制备6，9-二氟苯并异喹啉-5，10-二酮的工艺
CN106366036B (zh) * 2016-08-18 2019-07-09 湖北丽益医药科技有限公司 6,9-双[(2-氨基乙基)氨基]苯并[g]异喹啉-5,10-二酮二马来酸盐及其合成工艺

Also Published As

Publication number Publication date
JPH06505244A (ja) 1994-06-16
EP0639183A1 (de) 1995-02-22
IE920704A1 (en) 1992-09-09
AU1276892A (en) 1992-10-06
ATE123220T1 (de) 1995-06-15
ITMI910618A0 (it) 1991-03-08
ITMI910618A1 (it) 1992-09-08
DE69226091D1 (de) 1998-08-06
TW197426B (de) 1993-01-01
WO1992015566A1 (en) 1992-09-17
IT1244755B (it) 1994-08-08
EP0639183B1 (de) 1998-07-01
NZ241856A (en) 1994-12-22
MX9200919A (es) 1992-09-30
ZA921648B (en) 1992-11-25
ATE167856T1 (de) 1998-07-15

Similar Documents

Publication Publication Date Title
CN109071521B (zh) 作为fgfr抑制剂的杂环化合物
DE69712745T2 (de) Pyrrolopyrimidinen und verfahren zu deren herstellung
EP0555347A1 (de) Substituierte indolizino[1,2-b]chinolinone
US11834432B2 (en) Substituted amino six-membered nitric heterocyclic ring compound and preparation and use thereof
US20020013322A1 (en) Novel compounds for enhancing chemotherapy
AU7182500A (en) New dihydrofuro (3,4-b) quinolin-1-one compounds, a process for their preparation and pharmaceutical compositions containing them
JP5668092B2 (ja) 抗腫瘍薬としての５，６，又は７−置換−３−（ヘテロ）アリールイソキノリンアミン誘導体
US4681882A (en) 4-alkoxy-pyrido[2,3-d]pyrimidine derivatives
EP0273401B1 (de) Isoindolin-1-on-Derivat und antiarrhythmisches Mittel
KR19990007836A (ko) 융합된 이미다조[1, 2-a]피리딘
IL101157A (en) History of aza- and diazea-anthracenedione N-oxides, process for their preparation and anigoidal preparations containing them
JP3497168B2 (ja) 抗腫瘍活性を有する２−アミノアルキル−５−アミノアルキルアミノ置換イソキノインダゾール−６−（２ｈ）−オン類
US5519029A (en) 2-aminoalkyl-5-aminoalkylamino substituted-isoquinoindazole-6(2H)-ones
KR20250037582A (ko) 암의 치료를 위한 치환된 이환형 헤테로아릴 설폰아미드 유도체
KR20250011138A (ko) Ptpn2 저해제
US4677108A (en) 4-oxo-pyrido[2,3-d]pyrimidinone derivatives
CA2260057A1 (en) Novel compounds
US5596097A (en) Hetero-annulated indazoles
CN116217578B (zh) 一类抑制mTOR同时降解GSPT1蛋白的双功能化合物
EP0574433B1 (de) 6,9-Bis(amino substituierte) Benzo(G)Phthalazin-5,10-Dionen als Antikrebs-mittel
US5604246A (en) 2-aminoalkyl-5-aminoalkylamino substituted-isoquinoindazole-6(2H)-ones
AU780528B2 (en) Fused azepinone cyclin dependent kinase inhibitors
CZ286654B6 (cs) 2-/2-/(2-hydroxyethyl) amino/ethyl/-5-//(2-methylamino)ethyl/amino/indazol/4,3-gh/isochinolin-6(2H) on, způsob jeho výroby a farmaceutický prostředek s jeho obsahem
AU4590302A (en) New indenoindolone compounds, a process for their preparation and pharmaceutical compositions containing them
US20020160994A1 (en) New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees