ZA921706B - Use of hydrophilic penetration agents in dermatological compositions for the treatment of onychomycoses,and corresponding compositions - Google Patents

Use of hydrophilic penetration agents in dermatological compositions for the treatment of onychomycoses,and corresponding compositions

Info

Publication number
ZA921706B
ZA921706B ZA921706A ZA921706A ZA921706B ZA 921706 B ZA921706 B ZA 921706B ZA 921706 A ZA921706 A ZA 921706A ZA 921706 A ZA921706 A ZA 921706A ZA 921706 B ZA921706 B ZA 921706B
Authority
ZA
South Africa
Prior art keywords
compositions
hydrophilic
agents
onychomycoses
treatment
Prior art date
Application number
ZA921706A
Other languages
English (en)
Inventor
Jean-Pierre Laugier
Laugier Jean-Pierre
Marie-France Rude
Rude Marie-France
Philippe Touzan
Touzan Philippe
Francois Ringenbach
Ringenbach Francois
Original Assignee
Oreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oreal filed Critical Oreal
Publication of ZA921706B publication Critical patent/ZA921706B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q3/00Manicure or pedicure preparations

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Cosmetics (AREA)
ZA921706A 1991-03-08 1992-03-06 Use of hydrophilic penetration agents in dermatological compositions for the treatment of onychomycoses,and corresponding compositions ZA921706B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9102838A FR2673537B1 (fr) 1991-03-08 1991-03-08 Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.

Publications (1)

Publication Number Publication Date
ZA921706B true ZA921706B (en) 1992-11-25

Family

ID=9410536

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA921706A ZA921706B (en) 1991-03-08 1992-03-06 Use of hydrophilic penetration agents in dermatological compositions for the treatment of onychomycoses,and corresponding compositions

Country Status (17)

Country Link
US (3) US5814305A (de)
EP (1) EP0503988B1 (de)
JP (1) JP3559973B2 (de)
AT (1) ATE190485T1 (de)
AU (1) AU1147092A (de)
BR (1) BR9200786A (de)
CA (1) CA2062341C (de)
CY (1) CY2233B1 (de)
DE (1) DE69230772T2 (de)
DK (1) DK0503988T3 (de)
ES (1) ES2144409T3 (de)
FR (1) FR2673537B1 (de)
GR (1) GR3033297T3 (de)
MX (1) MX9200965A (de)
PT (1) PT503988E (de)
SG (1) SG46660A1 (de)
ZA (1) ZA921706B (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681849A (en) * 1991-05-20 1997-10-28 Novartis Ag Ltd. Pharmaceutical composition for topical applications
US10172811B2 (en) 2013-02-07 2019-01-08 Polichem Sa Topical antifungal composition for treating onychomycosis

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2673537B1 (fr) 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
US6005001A (en) * 1991-05-20 1999-12-21 Novartis Ag (Formerly Sandoz Ag) Pharmaceutical composition
HU219480B (hu) 1991-05-23 2001-04-28 Novartis Ag. Eljárás gombás körömmegbetegségek ellen helyileg alkalmazható, allil-amin-származékot tartalmazó gyógyászati készítmények előállítására
US5652256A (en) * 1995-06-06 1997-07-29 Knowles; W. Roy Topical composition for fungal treatment
JP2001502317A (ja) * 1996-10-16 2001-02-20 アイ・ピー・アール・インシティチュート・フォー・ファーマシューティカル・リサーチ・エー・ジー 新規なキャリヤー系
CA2278328C (en) * 1998-02-09 2008-07-22 Macrochem Corporation Antifungal nail lacquer and method using same
US6231875B1 (en) * 1998-03-31 2001-05-15 Johnson & Johnson Consumer Companies, Inc. Acidified composition for topical treatment of nail and skin conditions
JP5170486B2 (ja) 1998-09-10 2013-03-27 バイオイコール ア−ゲー 局所適用性産物
US6159977A (en) * 1998-11-16 2000-12-12 Astan, Inc. Therapeutic anti-fungal nail preparation
US6517863B1 (en) 1999-01-20 2003-02-11 Usbiomaterials Corporation Compositions and methods for treating nails and adjacent tissues
DE10011081A1 (de) * 2000-03-09 2001-09-13 Aventis Pharma Gmbh Antiinfektive Wirkstoffkombinationen und ihre Verwendung zur topischen Behandlung von Pilzerkrankungen der Fuß- und Fingernägel
US8257688B2 (en) * 2000-03-27 2012-09-04 Taro Pharmaceuticals Industries Controlled delivery system of antifungal and keratolytic agents for local treatment of fungal infections of the nail and surrounding tissues
US7074392B1 (en) * 2000-03-27 2006-07-11 Taro Pharmaceutical Industries Limited Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections
GB0014448D0 (en) * 2000-06-13 2000-08-09 Novartis Ag Organic compounds
GB0019283D0 (en) * 2000-08-04 2000-09-27 Novartis Ag Organic compounds
WO2006057616A1 (en) * 2004-11-29 2006-06-01 Ambria Dermatology Ab A composition comprising at least 3 different diols
US6664292B2 (en) 2001-06-04 2003-12-16 Mark H. Bogart Methods for the treatment of nail fungus and other microbial and mycotic conditions and compositions useful therefor
US7244703B2 (en) 2001-06-22 2007-07-17 Bentley Pharmaceuticals, Inc. Pharmaceutical compositions and methods for peptide treatment
US6821508B2 (en) 2001-06-27 2004-11-23 Rutgers, The State University Composition and method for topical nail treatment
US20030049307A1 (en) * 2002-08-15 2003-03-13 Gyurik Robert J. Pharmaceutical composition
CA2495923A1 (en) * 2002-08-20 2004-03-04 Doren M. Pinnell Methods for treating fungal infections
FR2844197B1 (fr) * 2002-09-05 2006-06-23 Galderma Res & Dev Solution pour application ungueale et peri-ungeale
MXPA05002065A (es) * 2002-09-05 2005-06-08 Galderma Sa Solucion para aplicacion ungueal.
US20040126343A1 (en) * 2002-12-26 2004-07-01 Garshowitz Solomon David Nail drug delivery
EP1635770B1 (de) * 2003-03-21 2009-05-27 Nexmed Holdings, Inc. Antimykotischer nagellack und anwendungsverfahren
WO2004108114A2 (en) * 2003-03-31 2004-12-16 Dinesh Shantilal Patel Anti-fungal composition and a process for its manufacture
WO2005002561A1 (ja) * 2003-07-03 2005-01-13 Taisho Pharmaceutical Co.,Ltd. 外用抗真菌剤組成物
JP4784051B2 (ja) * 2003-07-03 2011-09-28 大正製薬株式会社 容器への吸着を防止した外用抗真菌組成物
US20070166249A1 (en) * 2003-08-25 2007-07-19 Hans Meyer Pharmaceutical and cosmetic formulations for treating fingernails
DE10341944A1 (de) * 2003-09-11 2005-04-28 York Pharma Plc Antimykotisch wirksame Nagellackformulierung mit substituierten 2-Aminothiazolen als Wirkstoff
CN101829319A (zh) 2003-12-08 2010-09-15 Cpex药品公司 用于胰岛素治疗的药用组合物及方法
US20050238672A1 (en) * 2004-04-27 2005-10-27 Nimni Marcel E Antifungal drug delivery
US7740875B2 (en) * 2004-10-08 2010-06-22 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US20060078580A1 (en) * 2004-10-08 2006-04-13 Mediquest Therapeutics, Inc. Organo-gel formulations for therapeutic applications
US20060078599A1 (en) * 2004-10-12 2006-04-13 Mathew Ebmeier Pharmaceutical composition applicable to body tissue
US20060275230A1 (en) 2004-12-10 2006-12-07 Frank Kochinke Compositions and methods for treating conditions of the nail unit
CN101115475A (zh) * 2004-12-10 2008-01-30 塔利马治疗公司 用于治疗指甲单位病症的组合物和方法
US20060165747A1 (en) * 2005-01-24 2006-07-27 David Rolf Antifungal composition, method and kit for topically treating onychomycosis
WO2006103638A2 (en) * 2005-03-31 2006-10-05 Ranbaxy Laboratories Limited Topical pharmaceutical compositions of terbinafine and processes for their preparation
CN103357015A (zh) * 2005-09-29 2013-10-23 瑞士商拜欧伊果公司 疣、指甲疾病、及指甲保养用之局部配方
MXPA05012961A (es) * 2005-11-30 2007-05-30 Fernando Ahumada Ayala Preparaciones para el cuidado de las unas que contienen clorhidrato de terbinafina.
EP1970076A4 (de) 2005-12-28 2012-12-12 Teikoku Seiyaku Kk Pharmazeutische zusammensetzung zum auftragen auf einen nagel
US20080299060A1 (en) * 2006-01-02 2008-12-04 Tlt Medical Ltd. Pharmaceutical Composition for the Treatment of Nail Diseases
WO2007098591A2 (en) * 2006-03-02 2007-09-07 Nuvo Research Inc. Topical nail formulation
CA2645070C (en) * 2006-03-08 2014-02-04 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
JP4861420B2 (ja) 2006-08-28 2012-01-25 久光製薬株式会社 爪用貼付剤
US20080135643A1 (en) * 2006-12-08 2008-06-12 Kimberly-Clark Worldwide, Inc. Pulsating spray dispensers
EP2526928B1 (de) 2007-02-05 2018-12-26 Biophile Corporation, Ltd Erhöhte Effektivität von Allylamin-Heilmittelverbindungen
US20080261986A1 (en) * 2007-03-30 2008-10-23 Friden Phillip M Pharmaceutical formulations for iontophoretic delivery of an anti-fungal drug
AU2008241071B2 (en) 2007-04-20 2013-11-14 Bioequal Ag Topically applicable fungicide agents for treating nails
US20080287912A1 (en) * 2007-05-14 2008-11-20 Horrigan Corporation Method, Device And Formulation For The Treatment Of Nail Disorders
JP5529539B2 (ja) * 2007-09-05 2014-06-25 株式会社ポーラファルマ 医薬組成物
CN101808639B (zh) * 2007-09-05 2012-12-05 宝丽制药股份有限公司 抗真菌医药组合物
EP2191827B1 (de) 2007-09-05 2013-10-30 Pola Pharma Inc. Antimykotische zusammensetzung
EP2207546A1 (de) * 2007-10-09 2010-07-21 Humco Holding Group, Inc. Antimykotische nagelbehandlung
US8221370B2 (en) * 2007-10-31 2012-07-17 Kimberly-Clark Worldwide, Inc. Personal care article with substrate surface topography for evoking a neurosensory skin response
US7802314B2 (en) * 2007-10-31 2010-09-28 Kimberly-Clark Worldwide, Inc. Hand-wear article with cutaneous sensory elements
WO2009071959A2 (en) * 2007-12-04 2009-06-11 Pannonpharma Gyógyszergyártó Kft. A composition in the form of a paint tincture or lacquer to treat fungal infections containing itraconazole and a process for the preparation thereof
US20090175810A1 (en) 2008-01-03 2009-07-09 Gareth Winckle Compositions and methods for treating diseases of the nail
US8193232B2 (en) * 2009-02-13 2012-06-05 Topica Pharmaceuticals, Inc. Anti-fungal formulation
CN102333546B (zh) 2009-02-26 2014-11-26 Brain生物技术研究与信息网络股份公司 用于在跨角蛋白的局部药物递送中使用表面活性蛋白的组合物、用途和方法
US20120309753A1 (en) * 2009-03-06 2012-12-06 Galderma Research & Development Method of dissolving antifungal agent, and compositions with a high concentration of antifungal agent, suitable for application to the nail
FR2942716B1 (fr) * 2009-03-06 2011-04-15 Galderma Res & Dev Methode de solubilisation d'agent antifongique et compositions a haute concentration en agent antifongique applicables sur l'ongle
EP2416757A2 (de) 2009-04-09 2012-02-15 Pola Pharma Inc. Antimykotische pharmazeutische zusammensetzung
KR101409792B1 (ko) 2009-04-09 2014-06-19 니혼노야쿠가부시키가이샤 항진균성 약제학적 조성물
DE102009038512A1 (de) 2009-07-30 2011-02-10 Technische Universität Braunschweig Arzneimittelformulierung zur Behandlung von Nagelerkrankungen
WO2011014850A2 (en) * 2009-07-31 2011-02-03 Nuvo Research Inc. Topical eutectic-based formulations
WO2011024620A1 (en) 2009-08-25 2011-03-03 Pola Pharma Inc. Antimycotic pharmaceutical composition
NL2003786C2 (en) 2009-11-11 2010-07-30 Medner B V COMPOSITION FOR TOPICAL APPLICATION, USES THEREOF, APPLICATOR DEVICE AND KIT OF PARTS.
WO2011079234A2 (en) 2009-12-23 2011-06-30 Nuvo Research Inc. Highly permeating terbinafine formulation
US8039494B1 (en) 2010-07-08 2011-10-18 Dow Pharmaceutical Sciences, Inc. Compositions and methods for treating diseases of the nail
US20120061267A1 (en) * 2010-09-14 2012-03-15 Sally Villalobos MediTowel Anti-Fungal Wipe
EP2462991A1 (de) 2010-12-13 2012-06-13 PQS Group B.V. Zusammensetzung und Verwendung eines fermentierten Olivblattprodukts zur Behandlung von Nagelinfektionen
CN105377355A (zh) 2013-03-14 2016-03-02 拇趾公司 治疗甲单元的感染、疾病或病症的方法
AU2014329421B2 (en) 2013-10-03 2018-08-02 Dow Pharmaceutical Sciences, Inc. Stabilized efinaconazole compositions
JP6611014B2 (ja) 2013-11-22 2019-11-27 ボシュ ヘルス アイルランド リミテッド 抗感染方法、抗感染組成物、および抗感染装置
WO2016015094A1 (en) * 2014-07-31 2016-02-04 Acrux Dds Pty Ltd Topical composition
CN108472272A (zh) * 2015-08-17 2018-08-31 俄亥俄州国家创新基金会 用于ar-12的增强的透甲递送的方法和组合物
CN108135844A (zh) * 2015-10-07 2018-06-08 埃克索多斯生命科学有限合伙公司 局部用抗真菌组合物
US10993890B2 (en) 2018-03-15 2021-05-04 Pelli Skin Co., Llc Antifungal solution and foot wipe
CN108653195A (zh) * 2018-08-08 2018-10-16 江苏知原药业有限公司 透皮或透粘膜给药制剂
KR20210107043A (ko) * 2018-12-19 2021-08-31 말린즈 파마 엘엘씨 국소 조성물
WO2020231800A1 (en) * 2019-05-10 2020-11-19 Encube Ethicals Private Limited Topical antifungal formulation
EP4129292A1 (de) 2021-08-04 2023-02-08 OnychoPharm GmbH Formulierung für substituierte 2-aminothiazole bei der behandlung von allgemeinen und bakteriellen pilzinfektionen des nagels

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator
CY1410A (en) * 1979-08-22 1988-04-22 Sandoz Ag Propenylamines, processes for their production, pharmaceutical compositions containing them and their use as pharmaceuticals
FR2572933B1 (fr) * 1981-04-06 1988-03-18 Sandoz Sa Compositions pharmaceutiques topiques a base de tizanidine
FR2502951B1 (fr) * 1981-04-06 1985-12-06 Sandoz Sa Compositions pharmaceutiques topiques sous forme d'une micro-emulsion
JPS60224638A (ja) * 1984-04-23 1985-11-09 Kao Corp 経皮吸収促進剤およびこれを含有する外用剤
JPS6169721A (ja) * 1984-09-13 1986-04-10 Kao Corp 抗真菌組成物
WO1987002580A1 (en) * 1985-11-04 1987-05-07 Dermatological Products Of Texas Film-forming, pharmaceutical vehicles for application of medicaments to nails, pharmaceutical compositions based on those vehicles, and methods of using same
US4886545A (en) * 1986-01-31 1989-12-12 Nelson Research & Development Company Compositions comprising 1-substituted azacycloalkanes and their uses
US5256647A (en) * 1986-01-31 1993-10-26 Whitby Research, Inc. Compositions comprising 1-substituted azacycloalkanes
US4946870A (en) * 1986-06-06 1990-08-07 Union Carbide Chemicals And Plastics Company Inc. Delivery systems for pharmaceutical or therapeutic actives
US4782059A (en) * 1986-09-29 1988-11-01 Merck & Co., Inc. Method of controlling mycotic infections and compositions therefor
FR2613227B1 (fr) * 1987-04-01 1990-12-28 Oreal Compositions pharmaceutiques a base de nitrate de miconazole ou de nitrate d'econazole dans le traitement des infections fongiques des ongles
DE3720147A1 (de) * 1987-06-16 1988-12-29 Hoechst Ag Antimykotisch wirksamer nagellack sowie verfahren zu dessen herstellung
US4920112A (en) * 1988-04-18 1990-04-24 Merck & Co., Inc. Fungicidal compositions and method
US5181914A (en) * 1988-08-22 1993-01-26 Zook Gerald P Medicating device for nails and adjacent tissue
US5116603A (en) * 1989-01-31 1992-05-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Oral antifungal preventative, and method of use
US5053227A (en) * 1989-03-22 1991-10-01 Cygnus Therapeutic Systems Skin permeation enhancer compositions, and methods and transdermal systems associated therewith
JP2797401B2 (ja) * 1989-04-19 1998-09-17 日産化学工業株式会社 爪用抗真菌剤組成物
FR2646603B1 (fr) * 1989-05-03 1991-07-12 Oreal Composition nettoyante
JPH0338522A (ja) * 1989-07-05 1991-02-19 Maruho Kk 抗真菌性組成物
JPH0338521A (ja) * 1989-07-05 1991-02-19 Maruho Kk 抗真菌性組成物
FR2673537B1 (fr) * 1991-03-08 1993-06-11 Oreal Utilisation d'agents de penetration hydrophiles dans les compositions dermatologiques pour le traitement des onychomycoses, et compositions correspondantes.
US5215520A (en) * 1991-09-17 1993-06-01 Centre Internationale De Recherches Dermatologiques Galderma (C.I.R.D. Galderma) Method for delivering an active substance topically or percutaneously
US5661170A (en) * 1994-03-21 1997-08-26 Woodward Laboratories, Inc. Antimicrobial compositions and methods for using the same

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681849A (en) * 1991-05-20 1997-10-28 Novartis Ag Ltd. Pharmaceutical composition for topical applications
US10172811B2 (en) 2013-02-07 2019-01-08 Polichem Sa Topical antifungal composition for treating onychomycosis

Also Published As

Publication number Publication date
CY2233B1 (en) 2003-04-18
US6455592B1 (en) 2002-09-24
AU1147092A (en) 1992-09-10
SG46660A1 (en) 1998-02-20
JP3559973B2 (ja) 2004-09-02
MX9200965A (es) 1992-09-01
JPH0585929A (ja) 1993-04-06
EP0503988A1 (de) 1992-09-16
CA2062341A1 (fr) 1992-09-09
US6143793A (en) 2000-11-07
PT503988E (pt) 2000-06-30
DK0503988T3 (da) 2000-07-24
EP0503988B1 (de) 2000-03-15
FR2673537A1 (fr) 1992-09-11
ES2144409T3 (es) 2000-06-16
US5814305A (en) 1998-09-29
BR9200786A (pt) 1992-11-17
FR2673537B1 (fr) 1993-06-11
DE69230772D1 (de) 2000-04-20
GR3033297T3 (en) 2000-09-29
CA2062341C (fr) 2004-05-11
DE69230772T2 (de) 2000-07-27
ATE190485T1 (de) 2000-04-15

Similar Documents

Publication Publication Date Title
SG46660A1 (en) Use of hydrophilic penetration agents in dermatological compositions for the treatment of onychomycoses and corresponding compositions
EP0129284A3 (de) Besser durchdringende topische pharmazeutische Zusammensetzungen mit Gehalt an 1-Dodecyl-azacycloheptan-2-one
EP0857488A1 (de) Verfahren und Zusammensetzungen zur Erhöhung des Hautdurchtritts von Arzneistoffen unter Verwendung von Permeationsbeschleunigern
EP0857488A3 (de) Verfahren und Zusammensetzungen zur Erhöhung des Hautdurchtritts von Arzneistoffen unter Verwendung von Permeationsbeschleunigern
CA2241464A1 (en) Nisin in combination with glycerol monolaurate active against helicobacter
CA2284774A1 (en) Theobromine antitussive compositions
AU1449497A (en) Cyclosporin formulation
PL311637A1 (en) Poured over preparations containing a polymer as well as glycerides and glycols
IE781032L (en) Pharmaceutical compositions
AU6886987A (en) Veterinary compositions incorporating a water swellable polymer
WO1998029131A3 (en) Aqueous glycerol formulations of somatotropin
AU1783699A (en) Compositions for the transdermal and dermal administration of biologically active agents
HUT46506A (en) Insecticidal and game repellent synergetic compositions
KR920702623A (ko) 진해제