ZA9225B - Antibacterial agents. - Google Patents

Antibacterial agents.

Info

Publication number
ZA9225B
ZA9225B ZA9225A ZA9225A ZA9225B ZA 9225 B ZA9225 B ZA 9225B ZA 9225 A ZA9225 A ZA 9225A ZA 9225 A ZA9225 A ZA 9225A ZA 9225 B ZA9225 B ZA 9225B
Authority
ZA
South Africa
Prior art keywords
antibacterial agents
antibacterial
agents
Prior art date
Application number
ZA9225A
Other languages
English (en)
Inventor
Robert John Ternansky
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA9225B publication Critical patent/ZA9225B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
ZA9225A 1991-01-18 1992-01-02 Antibacterial agents. ZA9225B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/643,244 US5077287A (en) 1991-01-18 1991-01-18 3-thiazolylthio carbacephem antibacterial agents

Publications (1)

Publication Number Publication Date
ZA9225B true ZA9225B (en) 1993-07-02

Family

ID=24579974

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9225A ZA9225B (en) 1991-01-18 1992-01-02 Antibacterial agents.

Country Status (21)

Country Link
US (1) US5077287A (cs)
EP (1) EP0495585A1 (cs)
JP (1) JPH04321686A (cs)
KR (1) KR920014810A (cs)
CN (1) CN1063284A (cs)
AU (1) AU642334B2 (cs)
BR (1) BR9200058A (cs)
CA (1) CA2058592C (cs)
CZ (1) CZ281909B6 (cs)
FI (1) FI920110L (cs)
HU (1) HUT60268A (cs)
IE (1) IE920084A1 (cs)
IL (1) IL100575A (cs)
MX (1) MX9200105A (cs)
MY (1) MY131300A (cs)
NO (1) NO301328B1 (cs)
NZ (1) NZ241250A (cs)
PT (1) PT99984B (cs)
RU (1) RU2107067C1 (cs)
YU (1) YU2392A (cs)
ZA (1) ZA9225B (cs)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272265A (en) * 1990-02-12 1993-12-21 Eli Lilly And Company 3-(substituted or unsubstituted) thiazolo-1-carba (1-dethia)cephems
US5179088A (en) * 1990-02-12 1993-01-12 Eli Lilly And Company 1-carba(dethia)cephalosporin antibiotics
IL100576A (en) * 1991-01-18 1995-11-27 Eli Lilley And Company Cephalosporin antibiotics
JP3238209B2 (ja) * 1992-09-30 2001-12-10 塩野義製薬株式会社 チオメチルチオカルバセファロスポリン誘導体
US5525599A (en) * 1993-07-21 1996-06-11 Eli Lilly And Company 7-substituted-amino-3-substituted-3-cephem-4-carboxylic acids
DE4333697A1 (de) * 1993-10-02 1995-04-06 Merck Patent Gmbh Verfahren zur Herstellung von 3-Aminopyridinen aus 3-Nitropyridinen
US5496816A (en) * 1994-03-14 1996-03-05 Merck & Co., Inc. Carbapenem antibacterial compounds, compositions containing such compounds and methods of treatment
US5688786A (en) * 1994-04-01 1997-11-18 Microcide Pharmaceuticals, Inc. β-lactam antibiotics
US5698547A (en) * 1994-04-01 1997-12-16 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US5604218A (en) * 1994-04-01 1997-02-18 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US5498777A (en) * 1994-07-20 1996-03-12 Merck & Co., Inc. 3-thioheteroaryl cephalosporin compounds, compositions and methods of use
US5565445A (en) * 1995-02-22 1996-10-15 Merck & Co., Inc. 3-thioheteroaryl 1-carba-1-dethiacephalosporin compounds, compositions and methods of use
AU5985596A (en) * 1995-05-31 1996-12-18 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
MY127641A (en) * 1995-10-12 2006-12-29 Essential Therapeutics Inc Cephalosporin antibiotics
WO1998046566A1 (en) * 1997-04-17 1998-10-22 Microcide Pharmaceuticals, Inc. IMPROVED β-LACTAM ANTIBIOTICS
US6025352A (en) * 1997-09-29 2000-02-15 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US6030965A (en) * 1997-09-30 2000-02-29 Microcide Pharmaceuticals, Inc. Cephalosporin antibiotics
US6362009B1 (en) 1997-11-21 2002-03-26 Merck & Co., Inc. Solid phase synthesis of heterocycles
MXPA05011681A (es) * 2003-04-30 2006-06-27 Trine Pharmaceuticals Inc Antibioticos de carbacefen (-lactama.
US20080146535A1 (en) * 2003-04-30 2008-06-19 Tomasz Glinka Compositions comprising carbacephem beta-lactam antibiotics and beta-lactamase inhibitors
CN101835777A (zh) * 2007-10-25 2010-09-15 尔察祯有限公司 碳头孢烯β-内酰胺抗生素
WO2010030810A1 (en) * 2008-09-10 2010-03-18 Achaogen, Inc. Carbacephem beta-lactam antibiotics
WO2010123997A1 (en) * 2009-04-22 2010-10-28 Achaogen, Inc. Carbacephem beta-lactam antibiotics
US9433621B2 (en) 2010-02-18 2016-09-06 Merck Sharp & Dohme Corp. Substituted pyridine and pyrimidine derivatives and their use in treating viral infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA766941B (en) * 1975-11-21 1978-06-28 Merck & Co Inc 3-(substituted thio)cephalosporins,derivatives and nuclear analogues thereof
JPS60174787A (ja) * 1984-02-21 1985-09-09 Kyowa Hakko Kogyo Co Ltd 3位置換カルバセフエム化合物
JPH0653739B2 (ja) * 1984-11-15 1994-07-20 協和醗酵工業株式会社 3位置換カルバセフエム化合物
IL100576A (en) * 1991-01-18 1995-11-27 Eli Lilley And Company Cephalosporin antibiotics

Also Published As

Publication number Publication date
YU2392A (sh) 1994-12-28
AU1013592A (en) 1992-07-23
BR9200058A (pt) 1992-09-08
NZ241250A (en) 1993-02-25
NO920103D0 (no) 1992-01-08
HU9200081D0 (en) 1992-03-30
FI920110A7 (fi) 1992-07-19
FI920110A0 (fi) 1992-01-10
PT99984A (pt) 1993-01-29
HUT60268A (en) 1992-08-28
RU2107067C1 (ru) 1998-03-20
CN1063284A (zh) 1992-08-05
MX9200105A (es) 1992-07-01
MY131300A (en) 2007-08-30
NO301328B1 (no) 1997-10-13
IL100575A0 (en) 1992-09-06
EP0495585A1 (en) 1992-07-22
JPH04321686A (ja) 1992-11-11
KR920014810A (ko) 1992-08-25
CS1192A3 (en) 1992-08-12
AU642334B2 (en) 1993-10-14
FI920110L (fi) 1992-07-19
US5077287A (en) 1991-12-31
CA2058592C (en) 2001-12-25
CA2058592A1 (en) 1992-07-19
IE920084A1 (en) 1992-07-29
CZ281909B6 (cs) 1997-03-12
IL100575A (en) 1996-11-14
NO920103L (no) 1992-07-20
PT99984B (pt) 1999-06-30

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