ZA932170B - Topical and transdermal delivery system utilizing submicron oil spheres - Google Patents

Topical and transdermal delivery system utilizing submicron oil spheres

Info

Publication number
ZA932170B
ZA932170B ZA932170A ZA932170A ZA932170B ZA 932170 B ZA932170 B ZA 932170B ZA 932170 A ZA932170 A ZA 932170A ZA 932170 A ZA932170 A ZA 932170A ZA 932170 B ZA932170 B ZA 932170B
Authority
ZA
South Africa
Prior art keywords
delivery system
oil spheres
topical
submicron oil
transdermal delivery
Prior art date
Application number
ZA932170A
Other languages
English (en)
Inventor
Doron Friedman
Joseph Schwartz
Haim Aviv
Original Assignee
Pharmos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmos Corp filed Critical Pharmos Corp
Publication of ZA932170B publication Critical patent/ZA932170B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/062—Oil-in-water emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/21—Emulsions characterized by droplet sizes below 1 micron
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906—Drug delivery
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915—Therapeutic or pharmaceutical composition
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00—Nanotechnology
    • Y10S977/902—Specified use of nanostructure
    • Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/926—Topical chemical, e.g. cosmetic or sunscreen

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Birds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA932170A 1992-03-26 1993-03-26 Topical and transdermal delivery system utilizing submicron oil spheres ZA932170B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL10138792A IL101387A (en) 1992-03-26 1992-03-26 Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets
US08/036,116 US6004566A (en) 1992-03-26 1993-03-23 Topical and transdermal delivery system utilizing submicron oil spheres

Publications (1)

Publication Number Publication Date
ZA932170B true ZA932170B (en) 1993-10-28

Family

ID=26322424

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA932170A ZA932170B (en) 1992-03-26 1993-03-26 Topical and transdermal delivery system utilizing submicron oil spheres

Country Status (12)

Country Link
US (1) US6004566A (fr)
EP (1) EP0671903B1 (fr)
JP (1) JP4173533B2 (fr)
AT (1) ATE210425T1 (fr)
AU (1) AU684460B2 (fr)
CA (2) CA2132736C (fr)
DE (1) DE69331335T2 (fr)
DK (1) DK0671903T3 (fr)
ES (1) ES2169042T3 (fr)
IL (2) IL101387A (fr)
WO (1) WO1993018752A1 (fr)
ZA (1) ZA932170B (fr)

Families Citing this family (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ260018A (en) * 1994-03-03 1995-10-26 Bomac Lab Ltd Benzimidazole compositions and anthelmintic compositions
GB9409778D0 (en) 1994-05-16 1994-07-06 Dumex Ltd As Compositions
DE4440337A1 (de) * 1994-11-11 1996-05-15 Dds Drug Delivery Services Ges Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit
AT408067B (de) * 1995-03-17 2001-08-27 Gebro Pharma Gmbh Pharmazeutische zusammensetzung zur topischen applizierung und verfahren zu ihrer herstellung
EP0760237A1 (fr) * 1995-08-30 1997-03-05 Cipla Limited Microémulsions huile-dans-l'eau
EP0866689A1 (fr) * 1995-12-12 1998-09-30 Vesifact Ag Pulverisateur d'hydrocortisone pour administration topique
US6572880B2 (en) * 1996-10-24 2003-06-03 Pharmaceutical Applications Associates Llc Methods and transdermal compositions for pain relief
KR100294084B1 (ko) * 1998-06-02 2001-09-22 성재갑 비-스테로이드성소염진통제의경피흡수투여용조성물및이를포함하는경피흡수투여용제형
EP0858805A3 (fr) * 1997-02-13 1998-09-02 National Research Institute of Chinese Medicine Préparations de'oxicames transdermales
TWI241915B (en) 1998-05-11 2005-10-21 Ciba Sc Holding Ag A method of preparing a pharmaceutical end formulation using a nanodispersion
US6946144B1 (en) * 1998-07-08 2005-09-20 Oryxe Transdermal delivery system
US7220427B2 (en) * 1998-07-08 2007-05-22 Oryxe Mixture for transdermal delivery of low and high molecular weight compounds
JP4198318B2 (ja) 1998-08-19 2008-12-17 ヤーゴテック アクチェンゲゼルシャフト プロポフォールの注射可能水性分散物
IT1303692B1 (it) * 1998-11-03 2001-02-23 Chiesi Farma Spa Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.
FR2785803B1 (fr) * 1998-11-17 2005-03-25 Sanofi Sa Utilisation d'une substance se liant au recepteur peripherique des benzodiazepines dans le traitement des stress cutanes
US7393548B2 (en) * 1999-03-22 2008-07-01 J.P. M.E.D. Ltd. Nano oil in glycerin emulsion
IL138616A0 (en) * 2000-09-21 2001-10-31 J P M E D Ltd Oil in glycerin emulsion
EP1169016A1 (fr) * 1999-04-14 2002-01-09 The Procter & Gamble Company Composition transparente
IT1312088B1 (it) * 1999-04-21 2002-04-04 Altergon Sa Cerotto per uso topico contenente eparina e diclofenac.
US6515029B1 (en) 1999-04-23 2003-02-04 Kimberly-Clark Worldwide, Inc. Absorbent article having a hydrophilic lotionized bodyside liner
DE60012026T2 (de) * 1999-08-26 2004-12-30 Ganeden Biotech, Inc., San Diego Verwendung von emu-öl als träger für fungizide, antibakterielle und antivirale arzneien
AU7638200A (en) * 1999-10-20 2001-04-30 Vesifact Ag Microemulsion preconcentrates which contain cyclosporines and corresponding microemulsions
US6565879B1 (en) 1999-12-16 2003-05-20 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs with hydroxide-releasing agents as skin permeation enhancers
US20030104041A1 (en) * 1999-12-16 2003-06-05 Tsung-Min Hsu Transdermal and topical administration of drugs using basic permeation enhancers
US6558695B2 (en) * 1999-12-16 2003-05-06 Dermatrends, Inc. Topical and transdermal administration of peptidyl drugs using hydroxide releasing agents as permeation enhancers
US20050037073A1 (en) * 2000-01-13 2005-02-17 Alpharx Inc. Solid self-emulsifying dosage form for improved delivery of poorly soluble hydrophobic compounds and the process for preparation thereof
FR2805761B1 (fr) * 2000-03-02 2002-08-30 Mainelab Nanocapsules lipidiques, procede de preparation et utilisation comme medicament
AU2001245947A1 (en) * 2000-03-23 2001-10-03 Collaborative Technologies, Inc Method for preparing high pressure/high shear dispersions containing physiologically active ingredients
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
FR2811564B1 (fr) * 2000-07-13 2002-12-27 Oreal Nanoemulsion contenant des polymeres non ioniques, et ses utilisations notamment dans les domaines cosmetique, dermatologique, pharmaceutique et/ou ophtalmologique
US6756520B1 (en) 2000-10-20 2004-06-29 Kimberly-Clark Worldwide, Inc. Hydrophilic compositions for use on absorbent articles to enhance skin barrier
US6503526B1 (en) 2000-10-20 2003-01-07 Kimberly-Clark Worldwide, Inc. Absorbent articles enhancing skin barrier function
FR2823117A1 (fr) * 2000-11-14 2002-10-11 Pharmascience Lab Composition pharmaceutique ou cosmetique ainsi que l'utilisation d'au moins un compose actif pour inhiber la migration des cellules de langerhans
US20020165286A1 (en) * 2000-12-08 2002-11-07 Hanne Hedeman Dermal anti-inflammatory composition
US20020128615A1 (en) 2000-12-22 2002-09-12 Tyrrell David John Absorbent articles with non-aqueous compositions containing anionic polymers
US7771735B2 (en) 2000-12-22 2010-08-10 Kimberly-Clark Worldwide, Inc. Absorbent articles with compositions for reducing irritation response
US6749860B2 (en) 2000-12-22 2004-06-15 Kimberly-Clark Worldwide, Inc. Absorbent articles with non-aqueous compositions containing botanicals
JP4098967B2 (ja) * 2001-04-18 2008-06-11 花王株式会社 ダイラタンシー組成物
CA2447302C (fr) 2001-05-01 2008-07-29 A.V. Topchiev Institute Of Petrochemical Synthesis Composition bioadhesive biphase absorbant l'eau
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
RU2276998C2 (ru) 2001-05-01 2006-05-27 Институт Нефтехимического Синтеза Имени А.В. Топчиева Российской Академии Наук Гидрогелевые композиции
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
WO2002089849A1 (fr) * 2001-05-07 2002-11-14 Corium International Compositions et systemes d'administration d'un anesthesique local
US20040265268A1 (en) * 2001-08-18 2004-12-30 Deepak Jain Compositions and methods for skin rejuvenation and repair
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
DE10164531A1 (de) * 2001-12-31 2003-07-17 Pharmatech Gmbh Zubereitung zur Oberflächenanästhesie der Haut
JP4549625B2 (ja) 2002-01-05 2010-09-22 株式會社アモーレパシフィック 人参サポニン代謝産物を有効成分とする微細乳化粒子及びその製造方法、並びにこれを含有する皮膚老化防止用の化粧料組成物
DE10200578A1 (de) * 2002-01-09 2003-07-10 Roehm Gmbh Haft- und Bindemittel für dermale oder transdermale Therapiesysteme
US6579543B1 (en) * 2002-02-22 2003-06-17 Jackie H. McClung Composition for topical application to skin
IL157535A0 (en) * 2003-08-21 2004-03-28 Topimed Ltd Preparations for the prevention of skin atrophy
US20050059583A1 (en) 2003-09-15 2005-03-17 Allergan, Inc. Methods of providing therapeutic effects using cyclosporin components
US20060140990A1 (en) * 2003-09-19 2006-06-29 Drugtech Corporation Composition for topical treatment of mixed vaginal infections
AU2004274000B2 (en) 2003-09-19 2009-07-30 Drugtech Corporation Pharmaceutical delivery system
EP1713450B1 (fr) 2004-01-30 2021-10-06 Corium, Inc. Film a dissolution rapide pour la delivrance d'agent actif
CN101039706A (zh) 2004-08-05 2007-09-19 考里安国际公司 粘合剂组合物
KR100623013B1 (ko) * 2004-09-04 2006-09-19 김영대 나노에멀션, 그의 용도 및 제조방법
US7718674B2 (en) * 2004-09-27 2010-05-18 Bridge Pharma, Inc. Methods of relieving neuropathic pain with the S-isomer of 2-{2[N-(2-indanyl)-N-phenylamino]ethyl}piperidine
WO2006037047A2 (fr) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. R-isomere de 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine et autres agents anesthesiques dermiques
DE102004059613A1 (de) * 2004-12-10 2006-06-14 Liedtke, Rainer K., Dr. Zusammensetzung und Methode einer topischen Therapie von Neurodermitis
US20060222687A1 (en) * 2005-04-01 2006-10-05 Carter Stephen G Topical anesthetic
JP2008540534A (ja) * 2005-05-09 2008-11-20 ドラッグテック コーポレイション 放出調節薬学組成物
US20070015691A1 (en) 2005-07-13 2007-01-18 Allergan, Inc. Cyclosporin compositions
US9486408B2 (en) 2005-12-01 2016-11-08 University Of Massachusetts Lowell Botulinum nanoemulsions
AU2006332518A1 (en) * 2006-01-05 2007-07-12 Drugtech Corporation Composition and method of use thereof
CA2635994A1 (fr) * 2006-01-05 2007-07-12 Drugtech Corporation Systeme d'administration de medicament
CA2649149A1 (fr) * 2006-04-11 2007-10-25 Koko Kosmetikvertrieb Gmbh & Co. Kg Nanoparticules contenant de la nicotine et/ou de la cotinine, dispersions et leur utilisation
WO2008011161A2 (fr) * 2006-07-21 2008-01-24 Bridge Pharma, Inc. Composés anesthésiques dermiques
JP5432716B2 (ja) 2006-10-17 2014-03-05 ヌーボ リサーチ インコーポレイテッド ジクロフェナクゲル
CA2670694A1 (fr) * 2006-11-27 2008-11-20 National Research Council Of Canada Formulations de gel mou
WO2008070538A2 (fr) 2006-12-01 2008-06-12 Anterios, Inc. Nanoparticules à entités amphiphiles
SG10201607909WA (en) 2006-12-01 2016-11-29 Anterios Inc Peptide nanoparticles and uses therefor
US9918934B2 (en) * 2006-12-12 2018-03-20 Edgar Joel Acosta-Zara Linker-based lecithin microemulsion delivery vehicles
CN101765423B (zh) 2007-05-31 2014-08-06 安特里奥公司 核酸纳米粒子和其用途
EP2055298A1 (fr) * 2007-10-30 2009-05-06 Novartis AG Composition topique
WO2009063962A1 (fr) * 2007-11-16 2009-05-22 Techno Guard Co. Ltd. Emulsion grasse contenant un agent médicinal, et procédé de production de celle-ci
US7943187B2 (en) * 2008-05-23 2011-05-17 Bakr Rabie Paeoniflorin preparations and uses thereof for fat reduction
FR2934954B1 (fr) 2008-08-14 2011-07-22 Commissariat Energie Atomique Emulsion fluorescente de vert d'indocyanine
FR2934953B1 (fr) 2008-08-14 2011-01-21 Commissariat Energie Atomique Nanoemulsions de nanocristaux
FR2934955B1 (fr) 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions
AU2010204986B2 (en) 2009-01-14 2016-06-02 Corium International, Inc. Transdermal administration of tamsulosin
US8618164B2 (en) 2009-03-31 2013-12-31 Nuvo Research Inc. Treatment of pain with topical diclofenac compounds
SG10201401297QA (en) * 2009-04-08 2014-08-28 Cadila Healthcare Ltd Stable pharmaceutical compositions of diclofenac
WO2012053012A2 (fr) 2010-10-21 2012-04-26 Cadila Healthcare Limited Compositions pharmaceutiques topiques comprenant du thiocolchicoside
US20130295145A1 (en) 2010-10-21 2013-11-07 Cadila Healthcare Limited Topical pharmaceutical compositions comprising etodolac
WO2012053013A2 (fr) 2010-10-21 2012-04-26 Cadila Healthcare Limited Compositions pharmaceutiques d'agents anti-acné
PH12013500784A1 (en) 2010-10-21 2019-07-17 Cadila Healthcare Ltd Pharmaceutical compositions comprising nano size droplets of skin whitening agents
US9254257B2 (en) 2010-10-21 2016-02-09 Cadila Healthcare Limited Method for treatment of acne using pharmaceutical compositions of clindamycin
US9636353B2 (en) 2010-10-21 2017-05-02 Cadila Healthcare Limited Method for treatment of acne using pharmaceutical compositions of clindamycin and adapalene
WO2012053007A1 (fr) 2010-10-21 2012-04-26 Cadila Healthcare Limited Compositions pharmaceutiques topiques contenant des nanogouttelettes pour le traitement du psoriasis
US9789123B2 (en) 2010-10-21 2017-10-17 Cadila Healthcare Limited Topical pharmaceutical compositions containing nanodroplets for the treatment of psoriasis
WO2012127496A1 (fr) * 2011-03-01 2012-09-27 Cadila Healthcare Limited Compositions pharmaceutiques stables de lornoxicam ou des sels de celui-ci
US9713590B2 (en) * 2011-07-28 2017-07-25 Cadila Healthcare Limited Method for treatment of pain and inflammation
US8936814B2 (en) * 2012-11-30 2015-01-20 Zuri A. Murrell Skin cream
SG11201505076UA (en) 2012-12-31 2015-07-30 Jrx Biotechnology Inc Liquid topical pharmaceutical nano-emulsion formulations
DE102014102400A1 (de) * 2014-02-25 2015-08-27 Reinhard Caliebe Topische kosmetische oder pharmazeutische Zusammensetzung
US20170157257A1 (en) * 2014-03-27 2017-06-08 Pola Pharma Inc. Process for producing composition of emulsion preparation type
US11707436B2 (en) * 2014-12-15 2023-07-25 Nanosphere Health Sciences Inc. Methods of treating inflammatory disorders and global inflammation with compositions comprising phospholipid nanoparticle encapsulations of NSAIDS
US10596117B1 (en) * 2014-12-31 2020-03-24 Eric Morrison Lipoleosomes as carriers for aromatic amide anesthetic compounds
US11007161B1 (en) 2014-12-31 2021-05-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films
US11260018B2 (en) 2015-09-17 2022-03-01 Jrx Biotechnology, Inc. Approaches for improving skin hydration and moisturization
JP6721960B2 (ja) * 2015-09-28 2020-07-15 株式会社ポーラファルマ 皮膚外用剤及びその製造方法並びに有効成分の放出性の向上方法及び放出性の評価方法
US10172838B1 (en) 2016-03-15 2019-01-08 Florida A&M University Self-emulsifying formulation of CARP-1 functional mimetics
EP3541358A1 (fr) 2016-11-21 2019-09-25 Eirion Therapeutics, Inc. Administration transdermique de grands agents
KR20230011997A (ko) * 2020-05-13 2023-01-25 폴리클 파마 리미티드 모낭으로 생물활성제를 전달하기 위한 조성물
FR3120787B1 (fr) * 2021-03-19 2024-04-26 Algotherapeutix Composition pharmaceutique topique comprenant de l’amitriptyline et une phase aqueuse alcaline
RU2765470C1 (ru) * 2021-03-23 2022-01-31 Иршад Султанович Шарафутдинов Антибактериальное средство в форме геля на основе гентамицина и производного 2(5н)-фуранона

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE7713618L (sv) * 1977-12-01 1979-06-02 Astra Laekemedel Ab Lokalanestetisk blandning
EP0014509A3 (fr) * 1979-02-08 1981-02-11 THE PROCTER & GAMBLE COMPANY Compositions de conditionnement de la peau
JPS57171912A (en) * 1981-04-14 1982-10-22 Sumitomo Chem Co Ltd Cream
FR2520253A1 (fr) * 1982-01-28 1983-07-29 Oreal Nouveau systeme emulsionnant a base d'un condensat de proteines, d'un sterol polyoxyethylene et de phosphatide et son utilisation en cosmetique
US4613330A (en) * 1982-11-26 1986-09-23 Michelson Paul E Delivery system for desired agents
US4963367A (en) * 1984-04-27 1990-10-16 Medaphore, Inc. Drug delivery compositions and methods
JPH0647533B2 (ja) * 1984-08-10 1994-06-22 裕 水島 ４−ビフエニリル酢酸系化合物含有脂肪乳剤
IL88076A (en) * 1987-10-28 1993-01-14 Nippon Shinyaku Co Ltd Fat emulsions as drug carriers
CA1339029C (fr) * 1988-06-20 1997-04-01 Hiroyuki Kakoki Composition transparente
US5039527A (en) * 1989-02-24 1991-08-13 Medicontrol Corporation Hexamethylmelamine containing parenteral emulsions
AU614465B2 (en) * 1989-04-05 1991-08-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Medicinal emulsions
JPH0344322A (ja) * 1989-07-13 1991-02-26 Shiseido Co Ltd マイクロエマルション製剤及びその製造法
FR2655542B1 (fr) * 1989-12-13 1994-02-11 Oreal Composition cosmetique pour application topique contenant des huiles essentielles.
CA2052950A1 (fr) * 1990-10-10 1992-04-11 David P. Evitts Microemulsions aqueuses de tepoxalin a usage ophtalmique
AU658608B2 (en) * 1991-03-25 1995-04-27 Astellas Pharma Europe B.V. Topical preparation containing a suspension of solid lipid particles
CA2130357A1 (fr) * 1992-02-18 1993-08-19 Doron Friedman Compositions seches pour la preparation d'emulsions submicroniques
IL101241A (en) * 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier

Also Published As

Publication number Publication date
EP0671903A4 (fr) 1996-01-17
US6004566A (en) 1999-12-21
CA2132736A1 (fr) 1993-09-30
EP0671903A1 (fr) 1995-09-20
IL129921A (en) 2004-09-27
IL101387A0 (en) 1992-11-15
CA2590810A1 (fr) 1993-09-30
WO1993018752A1 (fr) 1993-09-30
ES2169042T3 (es) 2002-07-01
JP4173533B2 (ja) 2008-10-29
CA2132736C (fr) 2007-09-11
DK0671903T3 (da) 2002-04-15
EP0671903B1 (fr) 2001-12-12
IL129921A0 (en) 2000-02-29
DE69331335D1 (de) 2002-01-24
IL101387A (en) 1999-11-30
AU3935293A (en) 1993-10-21
AU684460B2 (en) 1997-12-18
JPH07505368A (ja) 1995-06-15
DE69331335T2 (de) 2002-08-08
ATE210425T1 (de) 2001-12-15

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