ZA93810B - Derivatives of pyridine, their preparation process, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions containing them - Google Patents

Derivatives of pyridine, their preparation process, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions containing them

Info

Publication number: ZA93810B
Authority: ZA; South Africa
Prior art keywords: radical; medicaments; pyridine; derivatives; application
Prior art date: 1992-02-07

Application number

ZA93810A

Other languages

English (en)

Inventor

Michel Fortin

Jean-Luc Haesslein

Bertrand Heckmann

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-07

Filing date

1993-02-05

Publication date

1994-02-07

1993-02-05 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1994-02-07 Publication of ZA93810B publication Critical patent/ZA93810B/xx

Links

239000003814 drug Substances 0.000 title abstract 2
239000000543 intermediate Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
150000003222 pyridines Chemical class 0.000 title 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000005018 aryl alkenyl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
-1 nitro, sulpho, formyl Chemical group 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
125000003396 thiol group Chemical class [H]S* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Neurology (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Pyrane Compounds (AREA)

ZA93810A 1992-02-07 1993-02-05 Derivatives of pyridine, their preparation process, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions containing them ZA93810B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9201390A FR2687674B1 (fr)	1992-02-07	1992-02-07	Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.

Publications (1)

Publication Number	Publication Date
ZA93810B true ZA93810B (en)	1994-02-07

Family

ID=9426432

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA93810A ZA93810B (en)	1992-02-07	1993-02-05	Derivatives of pyridine, their preparation process, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions containing them

Country Status (13)

Country	Link
EP (1)	EP0579819B1 (de)
JP (1)	JPH06506956A (de)
KR (1)	KR100273181B1 (de)
AT (1)	ATE313530T1 (de)
AU (1)	AU667880B2 (de)
CA (1)	CA2106758A1 (de)
DE (1)	DE69333944T2 (de)
ES (1)	ES2251714T3 (de)
FR (1)	FR2687674B1 (de)
HU (1)	HUT68756A (de)
RU (1)	RU2124004C1 (de)
WO (1)	WO1993016049A1 (de)
ZA (1)	ZA93810B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5866601A (en) *	1995-02-27	1999-02-02	Gilead Sciences, Inc.	Carbocyclic compounds
CN100409844C (zh)	1995-02-27	2008-08-13	吉里德科学公司	神经氨酸苷酶抑制剂
HUP9801766A3 (en) *	1995-05-19	2000-09-28	Biota Scient Managemant Pty Lt	6-carboxamido dihydropyran derivatives, process for producing them and medicaments containing the same
US5763483A (en) *	1995-12-29	1998-06-09	Gilead Sciences, Inc.	Carbocyclic compounds
US6518438B2 (en)	1996-08-23	2003-02-11	Gilead Sciences, Inc.	Preparation of cyclohexene carboxylate derivatives
US5859284A (en) *	1996-08-23	1999-01-12	Gilead Sciences, Inc.	Preparation of carbocyclic compounds
US5994377A (en) *	1996-10-21	1999-11-30	Gilead Sciences, Inc.	Piperidine compounds
TW477783B (en) *	1997-12-12	2002-03-01	Gilead Sciences Inc	Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
US6638937B2 (en)	1998-07-06	2003-10-28	Bristol-Myers Squibb Co.	Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
JP4556241B2 (ja) *	2003-02-05	2010-10-06	日本曹達株式会社	新規６−フルオロアルキル−２（１ｈ）−ピリジノン、６−フルオロアルキルピリジン化合物及びその製造方法
SE0302487D0 (sv) *	2003-09-18	2003-09-18	Astrazeneca Ab	Novel compounds
EP1749828A1 (de)	2005-08-04	2007-02-07	Farmaprojects S.L.	Verfahren zur Herstellung eines Angiotensin-II-Antagonisten
EP2542076B1 (de) *	2010-03-04	2021-01-13	Merck Sharp & Dohme Corp.	Hemmer der catechol-o-methyl-transferase und ihre verwendung bei der behandlung psychotischer störungen

Family Cites Families (20)

* Cited by examiner, † Cited by third party
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US4046769A (en) *	1976-10-29	1977-09-06	Warner-Lambert Company	4,10-Dihydro-4,10-dioxo-1H-1-benzopyrano[3,2-b]pyridine-2-carboxylic acids and esters
JPS56115784A (en) *	1980-02-15	1981-09-11	Tanabe Seiyaku Co Ltd	Novel pyridinecarboxamide derivative and its preparation
ZA813029B (en) *	1980-05-12	1982-05-26	Rohm & Haas	Novel substituted oxonicotinates,their use as plant growth regulators and plant growth regulating compositions containing them
GB8412208D0 (en) *	1984-05-12	1984-06-20	Pfizer Ltd	Quinolone inotropic agents
US4886744A (en) *	1985-04-25	1989-12-12	Polaroid Corporation	Fluorescent conjugates and biological diagnostic assay system
ES2004489A4 (es) *	1987-01-07	1989-01-16	Monsanto Co	Gametocidas de piridina.
US4747871A (en) *	1987-01-07	1988-05-31	Monsanto Company	2,6-bis(trifluoromethyl)-3-hydroxycarbonyl pyridine, salts and gametocides
US4751073A (en) *	1987-06-03	1988-06-14	Olin Corporation	Selected 2,2,6,6-tetraalkyl-4-piperidinyl derivatives and their use as light stabilizers
CA1338238C (en) *	1988-01-07	1996-04-09	David John Carini	Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
DE3826846A1 (de) *	1988-08-06	1990-02-08	Goedecke Ag	Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
US5077142A (en) *	1989-04-20	1991-12-31	Ricoh Company, Ltd.	Electroluminescent devices
DK0403159T3 (da) *	1989-06-14	2000-08-14	Smithkline Beecham Corp	Imidazolylalkensyrer
SG52709A1 (en) *	1989-06-30	1998-09-28	Du Pont	Substituted imidazoles
CA2036618C (en) *	1990-02-22	2002-10-29	Akira Morimoto	Fused thiophene derivatives, their production and use
CA2037630C (en) *	1990-03-07	2001-07-03	Akira Morimoto	Nitrogen-containing heterocylic compounds, their production and use
GB9005518D0 (en) *	1990-03-12	1990-05-09	Wellcome Found	Heterocyclic compounds
CA2051705A1 (en) *	1990-06-19	1991-12-20	Kiyoaki Katano	Pyridine derivatives having angiotensin ii antagonism
ATE128128T1 (de) *	1990-06-29	1995-10-15	Upjohn Co	Antiatherosclerotische und antithrombotische 2- amino-6-phenyl-4h-pyran-4-one.
IL98319A (en) *	1990-07-05	1997-04-15	Roussel Uclaf	Sulphurous derivatives of imidazole, their preparation process, and pharmaceutical compositions containing them
GB9102803D0 (en) *	1991-02-11	1991-03-27	Ici Plc	Pyridine compounds

1992
- 1992-02-07 FR FR9201390A patent/FR2687674B1/fr not_active Expired - Fee Related
1993
- 1993-02-05 CA CA002106758A patent/CA2106758A1/fr not_active Abandoned
- 1993-02-05 RU RU93058177A patent/RU2124004C1/ru active
- 1993-02-05 WO PCT/FR1993/000118 patent/WO1993016049A1/fr not_active Ceased
- 1993-02-05 ZA ZA93810A patent/ZA93810B/xx unknown
- 1993-02-05 HU HU9303144A patent/HUT68756A/hu unknown
- 1993-02-05 AT AT93905369T patent/ATE313530T1/de not_active IP Right Cessation
- 1993-02-05 DE DE69333944T patent/DE69333944T2/de not_active Expired - Fee Related
- 1993-02-05 EP EP93905369A patent/EP0579819B1/de not_active Expired - Lifetime
- 1993-02-05 JP JP5513829A patent/JPH06506956A/ja active Pending
- 1993-02-05 KR KR1019930703012A patent/KR100273181B1/ko not_active Expired - Fee Related
- 1993-02-05 AU AU36341/93A patent/AU667880B2/en not_active Ceased
- 1993-02-05 ES ES93905369T patent/ES2251714T3/es not_active Expired - Lifetime

Also Published As

Publication number	Publication date
RU2124004C1 (ru)	1998-12-27
FR2687674B1 (fr)	1995-05-19
DE69333944D1 (de)	2006-01-26
AU667880B2 (en)	1996-04-18
WO1993016049A1 (fr)	1993-08-19
EP0579819A1 (de)	1994-01-26
DE69333944T2 (de)	2006-08-10
ES2251714T3 (es)	2006-05-01
KR100273181B1 (ko)	2000-12-01
CA2106758A1 (fr)	1993-08-08
JPH06506956A (ja)	1994-08-04
HUT68756A (en)	1995-07-28
AU3634193A (en)	1993-09-03
EP0579819B1 (de)	2005-12-21
FR2687674A1 (fr)	1993-08-27
ATE313530T1 (de)	2006-01-15
HU9303144D0 (en)	1994-01-28

Publication	Publication Date	Title
ZA93810B (en)	1994-02-07	Derivatives of pyridine, their preparation process, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions containing them
FR2687675B1 (fr)	1997-04-18	Nouveaux derives bicycliques de la pyridine, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
DE10199003I2 (de)	2003-09-18
HUT60258A (en)	1992-08-28	Aminokumaran derivatives and process for producing aminokumaran derivatives and pharmaceutical compositions comprising such compounds
FR2377374A1 (fr)	1978-08-11	Derives acyles d'amino-acides et leur utilisation comme medicaments
GB8919434D0 (en)	1989-10-11	Novel compounds
HUT62602A (en)	1993-05-28	Process for producing pharmaceutically active hydrazine derivatives
IL116326A0 (en)	1996-03-31	Vitamin D compounds their preparation and pharmaceutical compositions containing them
HUP9802629A2 (hu)	1999-04-28	1,3-Bisz(1,2,4-triazolil)-2-propanol-származékok felhasználása rákos megbetegedések kezelésére szolgáló gyógyszerkészítmények előállítására
ZA886820B (en)	1989-11-29	Steroids containing a spiro ring with 3,4 or 6 links in position 17,the process and intermediates for their preparation,their use as medicaments and the pharmaceutical compositions containing them
MY105293A (en)	1994-09-30	Neuroprotective 3-piperino-4-hydroxychroman derivatives
ES2101513T3 (es)	1997-07-01	Nuevos taxoides, su preparacion y las composiciones farmaceuticas que les contienen.
IL86133A (en)	1992-05-25	Beta-d-phenylthioxylosides,their preparation and pharmaceutical compositions containing them
ES2064461T3 (es)	1995-02-01	Derivados de xantina, procedimiento para su preparacion y composicion farmaceutica.
FR2384790A1 (fr)	1978-10-20	Nouveaux antibiotiques et medicaments contenant ces substances
HU911121D0 (en)	1991-10-28	New 4-quinoline-dihydropyridine derivarives, process for producing them and their application in pharmaceutical products
GB1447462A (en)	1976-08-25	Alpha-thiolincosaminides and the preparation thereof
FR2399998A1 (fr)	1979-03-09	Produit derive de la diphenoxy-1,3 propanone-2, procede pour sa preparation et son application a la realisation d'un medicament
HU9402614D0 (en)	1994-11-28	Process for producing taxane derivatives
DK74189D0 (da)	1989-02-17	Laegemiddel til behandling af mavesaar
AU5111393A (en)	1994-05-09	Benzopyranones, method of preparing them and their use
FR2369312A1 (fr)	1978-05-26	Ethers oligomeres bromes et leur application comme ignifugeants
DE68904491D1 (de)	1993-03-04	Verwendung von adenosinderivaten zur herstellung von arzneimitteln mit immunstimulierender wirkung.
DE3866603D1 (de)	1992-01-16	1-benzoyl-2-oxo-5-alkoxy-pyrrolidin-derivate, ihre herstellung und verwendung als heilmittel und zubereitungen, die sie enthalten.
FI824062L (fi)	1983-05-27	Foerfarande foer framstaellning av ketaler av nya 3'''-dehydro-kardenolid-tridigitoxosider och anvaendning av dem som laekemedel