ZA93810B - Derivatives of pyridine, their preparation process, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions containing them - Google Patents

Derivatives of pyridine, their preparation process, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions containing them

Info

Publication number: ZA93810B
Authority: ZA; South Africa
Prior art keywords: radical; medicaments; pyridine; derivatives; application
Prior art date: 1992-02-07

Application number

ZA93810A

Other languages

English (en)

Inventor

Michel Fortin

Jean-Luc Haesslein

Bertrand Heckmann

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-02-07

Filing date

1993-02-05

Publication date

1994-02-07

1993-02-05 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1994-02-07 Publication of ZA93810B publication Critical patent/ZA93810B/xx

Links

239000003814 drug Substances 0.000 title abstract 2
239000000543 intermediate Substances 0.000 title 1
239000008194 pharmaceutical composition Substances 0.000 title 1
238000002360 preparation method Methods 0.000 title 1
150000003222 pyridines Chemical class 0.000 title 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000003342 alkenyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000000304 alkynyl group Chemical group 0.000 abstract 1
125000005018 aryl alkenyl group Chemical group 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
125000004093 cyano group Chemical group *C#N 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
-1 nitro, sulpho, formyl Chemical group 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
125000003396 thiol group Chemical class [H]S* 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/70—Sulfur atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/68—One oxygen atom attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Neurology (AREA)
Urology & Nephrology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Vascular Medicine (AREA)
Hospice & Palliative Care (AREA)
Psychiatry (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyridine Compounds (AREA)
Pyrane Compounds (AREA)

ZA93810A 1992-02-07 1993-02-05 Derivatives of pyridine, their preparation process, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions containing them ZA93810B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9201390A FR2687674B1 (fr)	1992-02-07	1992-02-07	Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.

Publications (1)

Publication Number	Publication Date
ZA93810B true ZA93810B (en)	1994-02-07

Family

ID=9426432

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA93810A ZA93810B (en)	1992-02-07	1993-02-05	Derivatives of pyridine, their preparation process, the new intermediates obtained, their application as medicaments and the pharmaceutical compositions containing them

Country Status (13)

Country	Link
EP (1)	EP0579819B1 (de)
JP (1)	JPH06506956A (de)
KR (1)	KR100273181B1 (de)
AT (1)	ATE313530T1 (de)
AU (1)	AU667880B2 (de)
CA (1)	CA2106758A1 (de)
DE (1)	DE69333944T2 (de)
ES (1)	ES2251714T3 (de)
FR (1)	FR2687674B1 (de)
HU (1)	HUT68756A (de)
RU (1)	RU2124004C1 (de)
WO (1)	WO1993016049A1 (de)
ZA (1)	ZA93810B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN100409844C (zh)	1995-02-27	2008-08-13	吉里德科学公司	神经氨酸苷酶抑制剂
US5866601A (en) *	1995-02-27	1999-02-02	Gilead Sciences, Inc.	Carbocyclic compounds
ATE206116T1 (de) *	1995-05-19	2001-10-15	Biota Scient Management	6-carboxamido-dihydropyran-derivate
US5763483A (en) *	1995-12-29	1998-06-09	Gilead Sciences, Inc.	Carbocyclic compounds
US5859284A (en) *	1996-08-23	1999-01-12	Gilead Sciences, Inc.	Preparation of carbocyclic compounds
US6518438B2 (en)	1996-08-23	2003-02-11	Gilead Sciences, Inc.	Preparation of cyclohexene carboxylate derivatives
US5994377A (en) *	1996-10-21	1999-11-30	Gilead Sciences, Inc.	Piperidine compounds
TW477783B (en) *	1997-12-12	2002-03-01	Gilead Sciences Inc	Novel compounds useful as neuraminidase inhibitors and pharmaceutical compositions containing same
US6638937B2 (en)	1998-07-06	2003-10-28	Bristol-Myers Squibb Co.	Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists
JP4556241B2 (ja) *	2003-02-05	2010-10-06	日本曹達株式会社	新規６−フルオロアルキル−２（１ｈ）−ピリジノン、６−フルオロアルキルピリジン化合物及びその製造方法
SE0302487D0 (sv) *	2003-09-18	2003-09-18	Astrazeneca Ab	Novel compounds
EP1749828A1 (de)	2005-08-04	2007-02-07	Farmaprojects S.L.	Verfahren zur Herstellung eines Angiotensin-II-Antagonisten
JP5995728B2 (ja) *	2010-03-04	2016-09-21	メルク・シャープ・エンド・ドーム・コーポレイション	カテコールｏ−メチルトランスフェラーゼの阻害剤および精神障害の治療におけるその使用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4046769A (en) *	1976-10-29	1977-09-06	Warner-Lambert Company	4,10-Dihydro-4,10-dioxo-1H-1-benzopyrano[3,2-b]pyridine-2-carboxylic acids and esters
JPS56115784A (en) *	1980-02-15	1981-09-11	Tanabe Seiyaku Co Ltd	Novel pyridinecarboxamide derivative and its preparation
NZ197027A (en) *	1980-05-12	1984-03-16	Rohm & Haas	4-oxo-2-phenyl-nicotinic acids salts and esters and growth regulating compositions
GB8412208D0 (en) *	1984-05-12	1984-06-20	Pfizer Ltd	Quinolone inotropic agents
US4886744A (en) *	1985-04-25	1989-12-12	Polaroid Corporation	Fluorescent conjugates and biological diagnostic assay system
US4747871A (en) *	1987-01-07	1988-05-31	Monsanto Company	2,6-bis(trifluoromethyl)-3-hydroxycarbonyl pyridine, salts and gametocides
EP0276204A3 (de) *	1987-01-07	1989-06-07	Monsanto Company	Pyridingametozide
US4751073A (en) *	1987-06-03	1988-06-14	Olin Corporation	Selected 2,2,6,6-tetraalkyl-4-piperidinyl derivatives and their use as light stabilizers
CA1338238C (en) *	1988-01-07	1996-04-09	David John Carini	Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
DE3826846A1 (de) *	1988-08-06	1990-02-08	Goedecke Ag	Alkoxy-4(1h)-pyridon-derivate, verfahren zu deren herstellung und deren verwendung als arzneimittel
US5077142A (en) *	1989-04-20	1991-12-31	Ricoh Company, Ltd.	Electroluminescent devices
SG52330A1 (en) *	1989-06-14	1998-09-28	Smithkline Beecham Corp	Imidazolyl-alkenoic acids
KR0163595B1 (ko) *	1989-06-30	1998-12-01	미리암디, 메코너헤이	치환된 이미다졸
CA2036618C (en) *	1990-02-22	2002-10-29	Akira Morimoto	Fused thiophene derivatives, their production and use
CA2037630C (en) *	1990-03-07	2001-07-03	Akira Morimoto	Nitrogen-containing heterocylic compounds, their production and use
GB9005518D0 (en) *	1990-03-12	1990-05-09	Wellcome Found	Heterocyclic compounds
KR100196559B1 (ko) *	1990-06-19	1999-06-15	기따사또 이찌로	안지오텐신ii 길항작용을 함유하는 피리딘 유도체
KR920702353A (ko) *	1990-06-29	1992-09-03	로버트 에이. 아미테이지	아테롬성 동맥경화증 및 혈전등 치료제인 2-아미노-6-페닐-4h-피란-4-온
IL98319A (en) *	1990-07-05	1997-04-15	Roussel Uclaf	Sulphurous derivatives of imidazole, their preparation process, and pharmaceutical compositions containing them
GB9102803D0 (en) *	1991-02-11	1991-03-27	Ici Plc	Pyridine compounds

1992
- 1992-02-07 FR FR9201390A patent/FR2687674B1/fr not_active Expired - Fee Related
1993
- 1993-02-05 AT AT93905369T patent/ATE313530T1/de not_active IP Right Cessation
- 1993-02-05 WO PCT/FR1993/000118 patent/WO1993016049A1/fr not_active Ceased
- 1993-02-05 JP JP5513829A patent/JPH06506956A/ja active Pending
- 1993-02-05 DE DE69333944T patent/DE69333944T2/de not_active Expired - Fee Related
- 1993-02-05 HU HU9303144A patent/HUT68756A/hu unknown
- 1993-02-05 CA CA002106758A patent/CA2106758A1/fr not_active Abandoned
- 1993-02-05 RU RU93058177A patent/RU2124004C1/ru active
- 1993-02-05 ES ES93905369T patent/ES2251714T3/es not_active Expired - Lifetime
- 1993-02-05 EP EP93905369A patent/EP0579819B1/de not_active Expired - Lifetime
- 1993-02-05 AU AU36341/93A patent/AU667880B2/en not_active Ceased
- 1993-02-05 KR KR1019930703012A patent/KR100273181B1/ko not_active Expired - Fee Related
- 1993-02-05 ZA ZA93810A patent/ZA93810B/xx unknown

Also Published As

Publication number	Publication date
FR2687674A1 (fr)	1993-08-27
EP0579819B1 (de)	2005-12-21
HU9303144D0 (en)	1994-01-28
ES2251714T3 (es)	2006-05-01
KR100273181B1 (ko)	2000-12-01
DE69333944D1 (de)	2006-01-26
RU2124004C1 (ru)	1998-12-27
AU667880B2 (en)	1996-04-18
EP0579819A1 (de)	1994-01-26
CA2106758A1 (fr)	1993-08-08
WO1993016049A1 (fr)	1993-08-19
ATE313530T1 (de)	2006-01-15
DE69333944T2 (de)	2006-08-10
FR2687674B1 (fr)	1995-05-19
HUT68756A (en)	1995-07-28
AU3634193A (en)	1993-09-03
JPH06506956A (ja)	1994-08-04

Publication	Publication Date	Title
AU3634193A (en)	1993-09-03	Novel pyridone derivatives, preparation method therefor, novel intermediates thereby obtained, their use as drugs, and pharmaceutical compositions containing same
FR2687675B1 (fr)	1997-04-18	Nouveaux derives bicycliques de la pyridine, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
DE10199003I2 (de)	2003-09-18
AU660469B2 (en)	1995-06-29	Pharmacologically active hydrazine derivatives and processes for the preparation thereof
IL123293A (en)	2003-06-24	Piperidine derivatives, their preparation and pharmaceutical compositions containing them
HUT60258A (en)	1992-08-28	Aminokumaran derivatives and process for producing aminokumaran derivatives and pharmaceutical compositions comprising such compounds
IL116326A0 (en)	1996-03-31	Vitamin D compounds their preparation and pharmaceutical compositions containing them
HUP9802629A2 (hu)	1999-04-28	1,3-Bisz(1,2,4-triazolil)-2-propanol-származékok felhasználása rákos megbetegedések kezelésére szolgáló gyógyszerkészítmények előállítására
ZA886820B (en)	1989-11-29	Steroids containing a spiro ring with 3,4 or 6 links in position 17,the process and intermediates for their preparation,their use as medicaments and the pharmaceutical compositions containing them
EP0356214A3 (de)	1990-08-08	Thiazolidindion-Derivate
FI904850A0 (fi)	1990-10-02	Menetelmä uusien terapeuttisesti käyttökelpoisten 24-homo-D-vitamiinijohdannaisten valmistamiseksi
ES2101513T3 (es)	1997-07-01	Nuevos taxoides, su preparacion y las composiciones farmaceuticas que les contienen.
NZ231380A (en)	1992-12-23	Xanthine derivatives and pharmaceutical compositions
IL97753A0 (en)	1992-06-21	4-quinolyl-dihydropyridines,their preparation and pharmaceutical compositions containing them
FR2393793A1 (fr)	1979-01-05	Derives de dichloro-3,3 azetidinones-2 a substituants basiques, leur procede de preparation et leur utilisation comme medicaments anti-inflammatoires
FR2399998A1 (fr)	1979-03-09	Produit derive de la diphenoxy-1,3 propanone-2, procede pour sa preparation et son application a la realisation d'un medicament
FR2412563A1 (fr)	1979-07-20	2-desoxyfortimicine a et derives 4-n-alkyl et 4-n-acyl-2-desoxyfortimicine b, utiles notamment comme antibiotiques, et intermediaires pour leur preparation
DK74189D0 (da)	1989-02-17	Laegemiddel til behandling af mavesaar
DE68904491D1 (de)	1993-03-04	Verwendung von adenosinderivaten zur herstellung von arzneimitteln mit immunstimulierender wirkung.
FR2677027B1 (fr)	1993-09-10	Nouveaux produits sterouides substitues en position 6, et comportant, en position 10, un radical thioethyle, leur procede de preparation leurs intermediaires, leur application comme medicaments.
DE3866603D1 (de)	1992-01-16	1-benzoyl-2-oxo-5-alkoxy-pyrrolidin-derivate, ihre herstellung und verwendung als heilmittel und zubereitungen, die sie enthalten.
FI824062L (fi)	1983-05-27	Foerfarande foer framstaellning av ketaler av nya 3'''-dehydro-kardenolid-tridigitoxosider och anvaendning av dem som laekemedel
ES2000614A6 (es)	1988-03-01	Procedimiento de obtencion de nuevos complejos de platino (ii) derivados del 2,3-dimercapto-2-butene-dinitrilato (2-)-s,s'"
GB1247993A (en)	1971-09-29	Substituted sulfanilamides
TH286A (th)	1982-04-30	กรรมวิธีการสังเคราะห์ไซคลิคแอมีด