ZA948025B - Methods for treating resistant neoplasms - Google Patents
Methods for treating resistant neoplasmsInfo
- Publication number
- ZA948025B ZA948025B ZA948025A ZA948025A ZA948025B ZA 948025 B ZA948025 B ZA 948025B ZA 948025 A ZA948025 A ZA 948025A ZA 948025 A ZA948025 A ZA 948025A ZA 948025 B ZA948025 B ZA 948025B
- Authority
- ZA
- South Africa
- Prior art keywords
- chem
- methods
- treating resistant
- resistant neoplasms
- neoplasms
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- -1 pyrrolidino, hexamethyleneimino Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13767893A | 1993-10-15 | 1993-10-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA948025B true ZA948025B (en) | 1996-04-15 |
Family
ID=22478575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA948025A ZA948025B (en) | 1993-10-15 | 1994-10-13 | Methods for treating resistant neoplasms |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0652004B1 (da) |
| JP (1) | JPH07149638A (da) |
| KR (1) | KR950010891A (da) |
| CN (1) | CN1108094A (da) |
| AT (1) | ATE220323T1 (da) |
| AU (1) | AU670518B2 (da) |
| CA (1) | CA2118096A1 (da) |
| CZ (1) | CZ253694A3 (da) |
| DE (1) | DE69430940T2 (da) |
| DK (1) | DK0652004T3 (da) |
| ES (1) | ES2179063T3 (da) |
| HU (1) | HUT71237A (da) |
| IL (1) | IL111287A0 (da) |
| NO (1) | NO943874L (da) |
| PT (1) | PT652004E (da) |
| RU (1) | RU94037233A (da) |
| ZA (1) | ZA948025B (da) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5441964A (en) * | 1993-10-15 | 1995-08-15 | Eli Lilly And Company | Methods for inhibiting bone loss using substituted benzothiophene |
| EP0777476A4 (en) * | 1994-08-22 | 1999-06-23 | Lilly Co Eli | METHOD FOR INHIBITING ENDOMETRIUM CANCER |
| ZA956988B (en) * | 1994-08-22 | 1997-02-21 | Lilly Co Eli | Methods of inhibiting primary endometrial hyperplasia. |
| JPH10505348A (ja) * | 1994-08-31 | 1998-05-26 | イーライ・リリー・アンド・カンパニー | 耐性腫瘍の同定および治療方法 |
| IL115582A0 (en) * | 1994-10-14 | 1996-01-19 | Lilly Co Eli | Methods for treating resistant tumors |
| ZA961564B (en) * | 1995-02-28 | 1997-08-27 | Lilly Co Eli | Methods of inhibiting ovarian cancer. |
| US5843974A (en) * | 1995-06-06 | 1998-12-01 | Eli Lilly And Company | Methods of inhibiting melanoma using Benzothiophenes as cytotoxic agents per se |
| EP0773217A1 (en) * | 1995-11-07 | 1997-05-14 | Eli Lilly And Company | Benzothiphene derivatives for treating resistant tumors |
| CZ235398A3 (cs) * | 1996-01-29 | 1999-02-17 | Eli Lilly And Company | Farmaceutický prostředek pro inhibici muskuloaponeurotických fibromatóz savců zvláště lidí |
| ID15917A (id) * | 1996-01-29 | 1997-08-21 | Lilly Co Eli | Metode untuk menghambat tumor usus besar |
| US5670523A (en) * | 1996-01-29 | 1997-09-23 | Eli Lilly And Company | Methods of inhibiting musculoaponeurotic fibromatoses (desmoid tumors) |
| TW442286B (en) * | 1996-02-28 | 2001-06-23 | Pfizer | New therapeutic uses of estrogen agonists |
| IL120266A (en) * | 1996-02-28 | 2005-05-17 | Pfizer | Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions |
| CZ341297A3 (cs) * | 1996-10-30 | 1998-05-13 | Eli Lilly And Company | Způsob zlepšení léčby nebo profylaxe rakoviny prsu |
| US6025373A (en) * | 1997-04-22 | 2000-02-15 | Eli Lilly And Company | Methods for reducing fibrinogen |
| EP1392304A1 (en) * | 2001-05-10 | 2004-03-03 | Cedars Sinai Medical Center | Use of benzothiophenes to treat and prevent prostate cancer |
| US7425565B2 (en) * | 2002-05-09 | 2008-09-16 | Cedars-Sinai Medical Center | Use of benzothiopenes to treat and prevent prostate cancer |
| FR2873692B1 (fr) * | 2004-07-29 | 2006-12-01 | Univ Claude Bernard Lyon | COMPOSITIONS CONTENANT, EN ASSOCIATION AVEC UN AGENT ANTIMICROBIEN, UN COMPOSE THIOPHENIQUE OU BENZOTHIOPHENIQUE DE FORMULE(I)PRESENTANT UNE ACTIVITE INHIBITRICE DE POMPE NorA |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
-
1994
- 1994-10-13 CA CA002118096A patent/CA2118096A1/en not_active Abandoned
- 1994-10-13 NO NO943874A patent/NO943874L/no unknown
- 1994-10-13 ES ES94307527T patent/ES2179063T3/es not_active Expired - Lifetime
- 1994-10-13 RU RU94037233/14A patent/RU94037233A/ru unknown
- 1994-10-13 DE DE69430940T patent/DE69430940T2/de not_active Expired - Fee Related
- 1994-10-13 KR KR1019940026162A patent/KR950010891A/ko not_active Withdrawn
- 1994-10-13 EP EP94307527A patent/EP0652004B1/en not_active Expired - Lifetime
- 1994-10-13 ZA ZA948025A patent/ZA948025B/xx unknown
- 1994-10-13 JP JP6247763A patent/JPH07149638A/ja not_active Withdrawn
- 1994-10-13 CZ CZ942536A patent/CZ253694A3/cs unknown
- 1994-10-13 AT AT94307527T patent/ATE220323T1/de not_active IP Right Cessation
- 1994-10-13 HU HU9402961A patent/HUT71237A/hu unknown
- 1994-10-13 IL IL11128794A patent/IL111287A0/xx unknown
- 1994-10-13 PT PT94307527T patent/PT652004E/pt unknown
- 1994-10-13 AU AU75786/94A patent/AU670518B2/en not_active Ceased
- 1994-10-13 DK DK94307527T patent/DK0652004T3/da active
- 1994-10-13 CN CN94117124A patent/CN1108094A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CZ253694A3 (en) | 1995-05-17 |
| DK0652004T3 (da) | 2002-09-02 |
| AU670518B2 (en) | 1996-07-18 |
| KR950010891A (ko) | 1995-05-15 |
| EP0652004A1 (en) | 1995-05-10 |
| DE69430940D1 (de) | 2002-08-14 |
| ES2179063T3 (es) | 2003-01-16 |
| NO943874D0 (no) | 1994-10-13 |
| CN1108094A (zh) | 1995-09-13 |
| AU7578694A (en) | 1995-05-04 |
| RU94037233A (ru) | 1996-08-27 |
| HUT71237A (en) | 1995-11-28 |
| ATE220323T1 (de) | 2002-07-15 |
| NO943874L (no) | 1995-04-18 |
| HU9402961D0 (en) | 1995-02-28 |
| CA2118096A1 (en) | 1995-04-16 |
| PT652004E (pt) | 2002-10-31 |
| IL111287A0 (en) | 1994-12-29 |
| DE69430940T2 (de) | 2003-04-03 |
| JPH07149638A (ja) | 1995-06-13 |
| EP0652004B1 (en) | 2002-07-10 |
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