ZA954451B - The cytoplasmic inhibition of gene expression - Google Patents

The cytoplasmic inhibition of gene expression

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Publication number
ZA954451B
ZA954451B ZA954451A ZA954451A ZA954451B ZA 954451 B ZA954451 B ZA 954451B ZA 954451 A ZA954451 A ZA 954451A ZA 954451 A ZA954451 A ZA 954451A ZA 954451 B ZA954451 B ZA 954451B
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ZA
South Africa
Prior art keywords
gene expression
invention concerns
plant cell
plant
cytoplasmic inhibition
Prior art date
Application number
ZA954451A
Other languages
English (en)
Inventor
Monto H Kumagai
Guy R Della-Cioppa
Jonathan Donson
Damon A Harvey
Original Assignee
Biosource Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosource Tech Inc filed Critical Biosource Tech Inc
Publication of ZA954451B publication Critical patent/ZA954451B/xx

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ZA954451A 1994-06-16 1995-05-31 The cytoplasmic inhibition of gene expression ZA954451B (en)

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Families Citing this family (160)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6054566A (en) * 1988-02-26 2000-04-25 Biosource Technologies, Inc. Recombinant animal viral nucleic acids
US20030150019A1 (en) * 1988-02-26 2003-08-07 Large Scale Biology Corporation Monopartite RNA virus transformation vectors
US5922602A (en) * 1988-02-26 1999-07-13 Biosource Technologies, Inc. Cytoplasmic inhibition of gene expression
GB9611981D0 (en) * 1996-06-07 1996-08-07 Zeneca Ltd Enhancement of gene expression
US6429356B1 (en) 1996-08-09 2002-08-06 Calgene Llc Methods for producing carotenoid compounds, and specialty oils in plant seeds
JP2001505409A (ja) * 1996-08-09 2001-04-24 カルジーン エルエルシー 植物種子中のカロチノイド化合物と特殊油の製造方法
GB9703146D0 (en) * 1997-02-14 1997-04-02 Innes John Centre Innov Ltd Methods and means for gene silencing in transgenic plants
US6586661B1 (en) 1997-06-12 2003-07-01 North Carolina State University Regulation of quinolate phosphoribosyl transferase expression by transformation with a tobacco quinolate phosphoribosyl transferase nucleic acid
GB9720148D0 (en) * 1997-09-22 1997-11-26 Innes John Centre Innov Ltd Gene silencing materials and methods
US6077992A (en) * 1997-10-24 2000-06-20 E. I. Du Pont De Nemours And Company Binary viral expression system in plants
US6632980B1 (en) 1997-10-24 2003-10-14 E. I. Du Pont De Nemours And Company Binary viral expression system in plants
US6506559B1 (en) 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
US6468745B1 (en) * 1998-01-16 2002-10-22 Large Scale Biology Corporation Method for expressing a library of nucleic acid sequence variants and selecting desired traits
US6700040B2 (en) 1998-01-16 2004-03-02 Large Scale Biology Corporation Cytoplasmic gene inhibition or gene expression in transfected plants by a tobraviral vector
US6426185B1 (en) 1998-01-16 2002-07-30 Large Scale Biology Corporation Method of compiling a functional gene profile in a plant by transfecting a nucleic acid sequence of a donor plant into a different host plant in an anti-sense orientation
US20020164585A1 (en) * 1998-01-16 2002-11-07 Sean Chapman Method for enhancing RNA or protein production using non-native 5' untranslated sequences in recombinant viral nucleic acids
US6300133B1 (en) 1998-01-16 2001-10-09 Large Scale Biology Corporation RNA transformation vectors derived from an uncapped single-component RNA virus
US20030027173A1 (en) * 1998-01-16 2003-02-06 Della-Cioppa Guy Method of determining the function of nucleotide sequences and the proteins they encode by transfecting the same into a host
US6300134B1 (en) 1998-01-16 2001-10-09 Large Scale Biology Corporation RNA transformation vectors derived from a single-component RNA virus and contain an intervening sequence between the cap and the 5′ end
CA2318662A1 (en) * 1998-01-16 1999-07-22 Biosource Technologies, Inc. Method of determining the function of nucleotide sequences and the proteins they encode by transfecting the same into a host
US6303848B1 (en) 1998-01-16 2001-10-16 Large Scale Biology Corporation Method for conferring herbicide, pest, or disease resistance in plant hosts
US6653530B1 (en) 1998-02-13 2003-11-25 Calgene Llc Methods for producing carotenoid compounds, tocopherol compounds, and specialty oils in plant seeds
AUPP249298A0 (en) 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
BRPI9908967B1 (pt) 1998-03-20 2017-05-30 Benitec Australia Ltd processos para reprimir, retardar ou de outro modo reduzir a expressão de um gene alvo em uma célula de planta
US6759571B1 (en) 1998-04-01 2004-07-06 North Carolina State University Method of suppressing gene expression in plants
AU760041B2 (en) 1998-04-08 2003-05-08 Commonwealth Scientific And Industrial Research Organisation Methods and means for obtaining modified phenotypes
AU3749199A (en) * 1998-04-24 1999-11-16 E.I. Du Pont De Nemours And Company Carotenoid biosynthesis enzymes
US6600089B1 (en) 1998-04-24 2003-07-29 E. I. Du Pont De Nemours And Company Carotenoid biosynthesis enzymes
FR2784688B1 (fr) * 1998-10-20 2002-12-13 Univ Grenoble 1 SEQUENCE D'ADNc DECRITE PAR SEQ ID N°1 TRANSCRIVANT UN ARNm CODANT POUR L'OXYDASE TERMINALE ASSOCIEE A LA BIOSYNTHESE DES CAROTENOIDES
WO2000044914A1 (en) * 1999-01-28 2000-08-03 Medical College Of Georgia Research Institute, Inc. Composition and method for in vivo and in vitro attenuation of gene expression using double stranded rna
MXPA01010488A (es) 1999-04-15 2003-07-21 Calgene Llc Secuencias de acidos nucleicos para proteinas que intervienen en sintesis isoprenoide.
AU775188B2 (en) * 1999-04-20 2004-07-22 Bayer Cropscience Nv Methods and means for delivering inhibitory RNA to plants and applications thereof
US7148400B1 (en) 1999-04-20 2006-12-12 Bayer Bioscience N.V. Methods and means for delivering inhibitory RNA to plants and applications thereof
DE19926216A1 (de) * 1999-06-09 2001-02-22 Metallgesellschaft Ag Verfahren zur Herstellung von Bariumsulfat, Bariumsulfat und Verwendung des Bariumsulfats
EP1196557A1 (en) * 1999-07-21 2002-04-17 Large Scale Biology Corporation Method of correlating sequence function by transfecting a nucleic acid sequence of a donor organism into a plant host in an anti-sense or positive sense orientation
US6423885B1 (en) 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
US6872815B1 (en) 2000-10-14 2005-03-29 Calgene Llc Nucleic acid sequences to proteins involved in tocopherol synthesis
US6841717B2 (en) 2000-08-07 2005-01-11 Monsanto Technology, L.L.C. Methyl-D-erythritol phosphate pathway genes
CN1330753C (zh) * 2000-08-30 2007-08-08 北卡罗莱纳州立大学 含有可改变蛋白含量的分子诱导物的转基因植物
DE10049587A1 (de) * 2000-10-06 2002-05-02 Icon Genetics Ag Vektorsystem für Pflanzen
WO2002038588A2 (en) 2000-11-07 2002-05-16 North Carolina State University Putrescine-n-methyltransferase promoter
DE10061150A1 (de) 2000-12-08 2002-06-13 Icon Genetics Ag Verfahren und Vektoren zur Erzeugung von transgenen Pflanzen
DE10102389A1 (de) 2001-01-19 2002-08-01 Icon Genetics Ag Verfahren und Vektoren zur Plastidentransformation höherer Pflanzen
US6800748B2 (en) * 2001-01-25 2004-10-05 Large Scale Biology Corporation Cytoplasmic inhibition of gene expression and expression of a foreign protein in a monocot plant by a plant viral vector
CA2369944A1 (en) 2001-01-31 2002-07-31 Nucleonics Inc. Use of post-transcriptional gene silencing for identifying nucleic acid sequences that modulate the function of a cell
DE10114209A1 (de) 2001-03-23 2002-12-05 Icon Genetics Ag Ortsgerichtete Transformation durch Verwendung von Amplifikationsvektoren
DE10115507A1 (de) 2001-03-29 2002-10-10 Icon Genetics Ag Verfahren zur Kodierung von Information in Nukleinsäuren eines genetisch veränderten Organismus
DE10121283B4 (de) 2001-04-30 2011-08-11 Icon Genetics GmbH, 80333 Verfahren und Vektoren zur Amplifikation oder Expression von gewünschten Nucleinsäuresequenzen in Pflanzen
US7161061B2 (en) 2001-05-09 2007-01-09 Monsanto Technology Llc Metabolite transporters
JP2004533244A (ja) 2001-05-09 2004-11-04 モンサント テクノロジー リミテッド ライアビリティー カンパニー TyrA遺伝子及びその使用法
EP1406518A4 (en) * 2001-06-08 2006-03-29 Vector Tobacco Ltd CHANGES IN NICOTINE AND NITROSAMINE LEVELS IN TOBACCO
DE10132780A1 (de) 2001-07-06 2003-01-16 Icon Genetics Ag Plastidäre Genexpression über autonom replizierende Vektoren
AU2002329759A1 (en) 2001-08-17 2003-03-03 Monsanto Technology Llc Methyltransferase genes and uses thereof
DE10143238A1 (de) 2001-09-04 2003-03-20 Icon Genetics Ag Identifizierung eukaryotischer interner Ribosomen-Eingangsstellen (IRES)-Elemente
DE10143237A1 (de) 2001-09-04 2003-03-20 Icon Genetics Ag Herstellung künstlicher interner ribosomaler Eingangsstellenelemente (Ires-Elemente)
EP1444348B1 (en) 2001-10-25 2010-01-27 Monsanto Technology LLC Aromatic methyltransferases and uses thereof
WO2003052108A2 (en) * 2001-12-18 2003-06-26 Bayer Bioscience N.V. Improved methods and means for delivering inhibitory rna to plants and applications thereof
US7229829B2 (en) * 2002-03-14 2007-06-12 Yale University Tobacco rattle virus vectors and related compositions and methods
EP1527180A4 (en) 2002-03-19 2006-02-15 Monsanto Technology Llc NUCLEIC ACIDS AND POLYPEPTIDES RELATING TO ENZYME HOMOGENTISATE PRENYL TRANSFERASE ("HPT"), AND USES THEREOF
DE10212892A1 (de) 2002-03-20 2003-10-09 Basf Plant Science Gmbh Konstrukte und Verfahren zur Regulation der Genexpression
WO2003086076A1 (en) * 2002-04-09 2003-10-23 Vector Tobacco Ltd. Tobacco having reduced nicotine and nitrosamines
US20060005282A1 (en) * 2002-04-23 2006-01-05 Activx Biosciences, Inc Production and use of salt tolerant and culture density tolerant organisms
US20040180438A1 (en) 2002-04-26 2004-09-16 Pachuk Catherine J. Methods and compositions for silencing genes without inducing toxicity
AU2003266014B2 (en) * 2002-05-06 2009-05-14 Alnylam Pharmaceuticals, Inc. Methods for delivery of nucleic acids
US20040126823A1 (en) * 2002-05-31 2004-07-01 Tsichlis Philip N. Modulation of prostaglandin synthesis and cancer growth
ATE546539T1 (de) 2002-07-26 2012-03-15 Basf Plant Science Gmbh Revertierung der negativ-selektiven wirkung von negativen markerproteinen als selektionsverfahren
WO2004011624A2 (en) * 2002-07-31 2004-02-05 Nucleonics, Inc. Double stranded rna structures and constructs, and methods for generating and using the same
US20050042646A1 (en) * 2002-08-05 2005-02-24 Davidson Beverly L. RNA interference suppresion of neurodegenerative diseases and methods of use thereof
US20040241854A1 (en) * 2002-08-05 2004-12-02 Davidson Beverly L. siRNA-mediated gene silencing
US20050255086A1 (en) * 2002-08-05 2005-11-17 Davidson Beverly L Nucleic acid silencing of Huntington's Disease gene
US20040023390A1 (en) * 2002-08-05 2004-02-05 Davidson Beverly L. SiRNA-mediated gene silencing with viral vectors
US20080274989A1 (en) 2002-08-05 2008-11-06 University Of Iowa Research Foundation Rna Interference Suppression of Neurodegenerative Diseases and Methods of Use Thereof
EP1546334A4 (en) 2002-08-05 2007-01-03 Monsanto Technology Llc GENES ASSOCIATED WITH TOCOPHEROL BIOSYNTHESIS AND USES THEREOF
US20080176812A1 (en) * 2002-08-05 2008-07-24 Davidson Beverly L Allele-specific silencing of disease genes
US20050106731A1 (en) * 2002-08-05 2005-05-19 Davidson Beverly L. siRNA-mediated gene silencing with viral vectors
WO2004044161A2 (en) * 2002-11-06 2004-05-27 Fraunhofer Usa Expression of foreign sequences in plants using trans-activation system
US7692063B2 (en) * 2002-11-12 2010-04-06 Ibio, Inc. Production of foreign nucleic acids and polypeptides in sprout systems
US7491509B2 (en) 2003-02-03 2009-02-17 Fraunhofer Usa, Inc. System for expression of genes in plants
US7683238B2 (en) * 2002-11-12 2010-03-23 iBio, Inc. and Fraunhofer USA, Inc. Production of pharmaceutically active proteins in sprouted seedlings
US20040248299A1 (en) * 2002-12-27 2004-12-09 Sumedha Jayasena RNA interference
US20050039228A1 (en) * 2003-06-19 2005-02-17 The Samuel Roberts Noble Foundation Methods and compositions for analysis of plant gene function
WO2005019449A2 (en) * 2003-07-03 2005-03-03 Board Of Trustees Operating Michigan State University Expression of a recombinant transgene
EP1769068B1 (en) * 2004-02-20 2014-12-31 iBio, Inc. Systems and methods for clonal expression in plants
US20050260652A1 (en) * 2004-04-15 2005-11-24 The General Hospital Corporation Compositions and methods that modulate RNA interference
US7644624B2 (en) 2004-06-04 2010-01-12 The Board Of Trustees Of The University Of Illinois Artificial lateral line
CN1330756C (zh) * 2005-03-14 2007-08-08 姜国勇 抗番茄花叶病毒基因及其分离方法
BRPI0608829A2 (pt) 2005-04-19 2011-03-15 Basf Plant Science Gmbh método para a expressão transgênica com especificidade intensificada em uma planta, uso de um construto de ácido nucleico quimérico, seqüência de ribonucleotìdeo quimérica, construto de expressão, vetor de expressão, organismo não-humano ou célula transformada, semente transformada, e, preparação farmacêutica
US9708619B2 (en) 2005-09-20 2017-07-18 Basf Plant Science Gmbh Methods for controlling gene expression using ta-siRNA
US8431080B2 (en) 2006-06-02 2013-04-30 The Board Of Trustees Of The University Of Illinois Soft MEMS
US7661319B2 (en) * 2006-06-02 2010-02-16 The Board Of Trustees Of The University Of Illinois Micromachined artificial haircell
WO2008005466A2 (en) * 2006-06-30 2008-01-10 The Board Of Trustees Of The University Of Illinois Artificial lateral line
EP2111451A1 (en) 2007-02-06 2009-10-28 BASF Plant Science GmbH Compositions and methods using rna interference for control of nematodes
ES2382408T3 (es) 2007-02-06 2012-06-08 Basf Plant Science Gmbh Uso de genes de la alanina racemasa para conferir a las plantas resistencia a los nemátodos
US20100115660A1 (en) 2007-02-08 2010-05-06 Basf Plant Science Gmbh Compositions and Methods Using RNA Interference of OPR3-Like Gene For Control of Nematodes
CA2677630A1 (en) 2007-02-09 2008-08-14 Basf Plant Science Gmbh Compositions and methods using rna interference of cdpk-like for control of nematodes
US20100095404A1 (en) 2007-03-15 2010-04-15 Basf Plant Science Gmbh Use of Nematode Chitinase Genes to Control Plant Parasitic Nematodes
US20100317078A1 (en) * 2007-08-27 2010-12-16 Cornell Research Foundation Inc Methods to improve alcohol tolerance of microorganisms
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
CA2717772A1 (en) * 2008-04-07 2009-10-15 Pioneer Hi-Bred International, Inc. Use of virus-induced gene silencing (vigs) to down-regulate genes in plants
DE112009002061T5 (de) 2008-08-27 2011-07-14 BASF Plant Science GmbH, 67063 Nematodenresistente transgene Pflanzen
US8536404B2 (en) 2008-12-11 2013-09-17 Basf Plant Science Gmbh Plant root-specific nematode resistance
MX2011009415A (es) 2009-03-20 2011-09-27 Basf Plant Science Co Gmbh Plantas transgenicas resistentes a los nematodos.
US20120151629A1 (en) 2009-08-25 2012-06-14 Basf Plant Science Company Gmbh Nematode-Resistant Transgenic Plants
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
EP2510090A1 (en) 2009-12-09 2012-10-17 BASF Plant Science Company GmbH Methods for increasing the resistance of plants to fungi by silencing the fungal smt1-gene
EP2539362A1 (en) 2010-02-23 2013-01-02 BASF Plant Science Company GmbH Nematode-resistant transgenic plants
PE20130649A1 (es) 2010-03-08 2013-07-13 Monsanto Technology Llc Moleculas polinucleotidicas para regulacion genetica en plantas
CA2802275A1 (en) 2010-06-16 2011-12-22 Plant Bioscience Limited Control of plant seed shattering
WO2012084756A1 (en) 2010-12-20 2012-06-28 Basf Plant Science Company Gmbh Nematode-resistant transgenic plants
EP2535416A1 (en) 2011-05-24 2012-12-19 BASF Plant Science Company GmbH Development of phytophthora resistant potato with increased yield
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
WO2013040116A1 (en) 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and compositions for weed control
CN103957697B (zh) 2011-09-13 2017-10-24 孟山都技术公司 用于杂草控制的方法和组合物
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
MX343072B (es) 2011-09-13 2016-10-21 Monsanto Technology Llc Metodos y composiciones para controlar malezas.
EP2755466A4 (en) 2011-09-13 2015-04-15 Monsanto Technology Llc METHOD AND COMPOSITIONS FOR WEED CONTROL
WO2013050593A1 (en) 2011-10-07 2013-04-11 Basf Plant Science Company Gmbh Method of producing plants having increased resistance to pathogens
WO2013050318A1 (en) 2011-10-07 2013-04-11 Basf Plant Science Company Gmbh Method of producing plants having increased resistance to pathogens
WO2013050611A1 (en) 2011-10-07 2013-04-11 Basf Plant Science Company Gmbh Method of producing plants having increased resistance to pathogens
WO2013053711A1 (en) 2011-10-10 2013-04-18 Basf Plant Science Company Gmbh Method of producing plants having increased resistance to pathogens
WO2013053686A1 (en) 2011-10-10 2013-04-18 Basf Plant Science Company Gmbh Method of producing plants having increased resistance to pathogens
US10240162B2 (en) 2012-05-24 2019-03-26 A.B. Seeds Ltd. Compositions and methods for silencing gene expression
AR093058A1 (es) 2012-10-18 2015-05-13 Monsanto Technology Llc Metodos y composiciones para el control de pestes en plantas
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
UA118841C2 (uk) 2013-01-01 2019-03-25 Ей.Бі. СІДС ЛТД. Спосіб формування рослини, яка має підвищену стійкість до комахи-шкідника
US20150342192A1 (en) 2013-01-15 2015-12-03 Monsanto Technology Llc Methods and Compositions for Plant Pest Control
US10000767B2 (en) 2013-01-28 2018-06-19 Monsanto Technology Llc Methods and compositions for plant pest control
US10462994B2 (en) 2013-01-29 2019-11-05 Basf Plant Science Company Gmbh Fungal resistant plants expressing HCP7
WO2014117990A1 (en) 2013-01-29 2014-08-07 Basf Plant Science Company Gmbh Fungal resistant plants expressing hcp6
WO2014118018A1 (en) 2013-01-29 2014-08-07 Basf Plant Science Company Gmbh Fungal resistant plants expressing ein2
CN105008542B (zh) 2013-03-08 2020-02-07 巴斯夫植物科学有限公司 表达MybTF的抗真菌性植物
EP2967082A4 (en) 2013-03-13 2016-11-02 Monsanto Technology Llc METHOD AND COMPOSITIONS FOR WEED CONTROL
WO2014164761A1 (en) 2013-03-13 2014-10-09 Monsanto Technology Llc Methods and compositions for weed control
US20140283211A1 (en) 2013-03-14 2014-09-18 Monsanto Technology Llc Methods and Compositions for Plant Pest Control
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
US10907166B2 (en) 2013-06-17 2021-02-02 Bayer Cropscience Aktiengesellschaft Method for identifying substances which prime cells for a stress response and cells for use in this method
CN105518136A (zh) 2013-07-10 2016-04-20 巴斯夫欧洲公司 用于通过抑制CYP51基因表达来控制致植物病真菌和卵菌的RNAi
JP6668236B2 (ja) 2013-07-19 2020-03-18 モンサント テクノロジー エルエルシー Leptinotarsa防除用組成物及びその方法
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
AU2014308078B2 (en) 2013-08-14 2018-04-05 Institute Of Genetics And Developmental Biology Methods of modulating seed and organ size in plants
MX390055B (es) 2013-11-04 2025-03-20 Monsanto Technology Llc Composiciones y metodos para controlar infestaciones de plagas y parasitos de los artropodos.
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
CN105979770B (zh) 2014-01-15 2019-07-05 孟山都技术公司 用于使用epsps多核苷酸的杂草控制的方法和组合物
BR112016022711A2 (pt) 2014-04-01 2017-10-31 Monsanto Technology Llc composições e métodos para controle de pragas de inseto
WO2015200223A1 (en) 2014-06-23 2015-12-30 Monsanto Technology Llc Compositions and methods for regulating gene expression via rna interference
US11807857B2 (en) 2014-06-25 2023-11-07 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
AU2015296700B2 (en) 2014-07-29 2021-10-21 Monsanto Technology Llc Compositions and methods for controlling insect pests
US10968449B2 (en) 2015-01-22 2021-04-06 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
CN107429259A (zh) 2015-02-04 2017-12-01 巴斯夫植物科学有限公司 通过增加莨菪亭含量,增加转基因植物中大豆锈病抗性的方法
US10883103B2 (en) 2015-06-02 2021-01-05 Monsanto Technology Llc Compositions and methods for delivery of a polynucleotide into a plant
EP3302030A4 (en) 2015-06-03 2019-04-24 Monsanto Technology LLC METHOD AND COMPOSITIONS FOR INTRODUCING NUCLEIC ACIDS IN PLANTS
EP3054014A3 (en) 2016-05-10 2016-11-23 BASF Plant Science Company GmbH Use of a fungicide on transgenic plants
GB201721600D0 (en) 2017-12-21 2018-02-07 Plant Bioscience Ltd Metabolic engineering
GB201808617D0 (en) 2018-05-25 2018-07-11 Plant Bioscience Ltd Scaffold modification
GB201908431D0 (en) 2019-06-12 2019-07-24 Plant Bioscience Ltd Biosynthetic genes and polypeptides
GB201909104D0 (en) 2019-06-25 2019-08-07 Plant Bioscience Ltd Transferase enzymes
CA3250471A1 (en) 2022-04-14 2023-10-19 Institute Of Agricultural Resources And Regional Planning Of The Chinese Academy Of Agricultural Sciences MICROALGAE MODIFIED FOR BETTER PHOSPHATE ABSORPTION INVOLVING THE OVEREXPRESSION OF PSR1 AND POSSIBLY THE UNDEREXPRESSION OF PTC1
GB202209501D0 (en) 2022-06-29 2022-08-10 Plant Bioscience Ltd Biosynthetic enzymes
LU503053B1 (en) 2022-11-14 2024-05-14 Univ Birmingham Somaclonal Variation

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59216245A (ja) 1983-05-25 1984-12-06 Nec Corp 正規化回路
US5190931A (en) * 1983-10-20 1993-03-02 The Research Foundation Of State University Of New York Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA
US5272065A (en) * 1983-10-20 1993-12-21 Research Foundation Of State University Of New York Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA
US5453566A (en) * 1986-03-28 1995-09-26 Calgene, Inc. Antisense regulation of gene expression in plant/cells
US5107065A (en) * 1986-03-28 1992-04-21 Calgene, Inc. Anti-sense regulation of gene expression in plant cells
AU612972B2 (en) * 1986-04-02 1991-07-25 Pioneer Hi-Bred International, Inc. Virus resistant plants having antisense rna
US5316931A (en) * 1988-02-26 1994-05-31 Biosource Genetics Corp. Plant viral vectors having heterologous subgenomic promoters for systemic expression of foreign genes
US5922602A (en) * 1988-02-26 1999-07-13 Biosource Technologies, Inc. Cytoplasmic inhibition of gene expression
US5034323A (en) * 1989-03-30 1991-07-23 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
US5231020A (en) * 1989-03-30 1993-07-27 Dna Plant Technology Corporation Genetic engineering of novel plant phenotypes
WO1990012107A1 (en) * 1989-03-31 1990-10-18 The Salk Institute Biotechnology/Industrial Associates, Inc. Recombinant expression system based on satellite tobacco mosaic virus
SE466123B (sv) 1989-04-25 1991-12-16 Kvaser Consultant Ab Anordning foer att synkonisera data i ett datoriserat system, som innefattar en gemensam seriell datakommunikationskanal
NL9001711A (nl) * 1989-10-03 1991-05-01 Clovis Matton N V Genetische manipulaties met recombinant dna, dat van rna virus afgeleide sequenties omvat.
GB8928179D0 (en) * 1989-12-13 1990-02-14 Ici Plc Dna,constructs,cells and plants derived therefrom
DE69132769T2 (de) * 1990-03-02 2002-04-18 Bp Corp. North America Inc., Chicago Biosynthese von carotinoiden in genetisch hergestellten wirtszellen
WO1991013994A1 (en) * 1990-03-13 1991-09-19 Commonwealth Scientific And Industrial Research Organisation Gene expression
ATE212671T1 (de) * 1991-08-01 2002-02-15 Large Scale Biology Corp Rekombinierte virale nukleinsäure aus pflanzen
GB9210273D0 (en) * 1992-05-13 1992-07-01 Ici Plc Dna
US5539093A (en) * 1994-06-16 1996-07-23 Fitzmaurice; Wayne P. DNA sequences encoding enzymes useful in carotenoid biosynthesis

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