ZA957877B - 17-deoxycorticosteroid-21-/O/-carboxylic esters processes for their preparation and pharmaceuticals containing these compounds - Google Patents

17-deoxycorticosteroid-21-/O/-carboxylic esters processes for their preparation and pharmaceuticals containing these compounds

Info

Publication number: ZA957877B
Authority: ZA; South Africa
Prior art keywords: opt; deoxycorticosteroid; compounds; preparation; carboxylic esters
Prior art date: 1994-09-20

Application number

ZA957877A

Other languages

English (en)

Inventor

Ulrich Stache

Hans-Georg Alpermann

Manfred Bohn

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-09-20

Filing date

1995-09-19

Publication date

1996-04-03

1995-09-19 Application filed by Hoechst Ag filed Critical Hoechst Ag

1996-04-03 Publication of ZA957877B publication Critical patent/ZA957877B/xx

Links

150000001875 compounds Chemical class 0.000 title 1
239000003814 drug Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
125000001072 heteroaryl group Chemical group 0.000 abstract 1
229910052757 nitrogen Inorganic materials 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
229910052717 sulfur Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of only two carbon atoms, e.g. pregnane derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Saccharide Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA957877A 1994-09-20 1995-09-19 17-deoxycorticosteroid-21-/O/-carboxylic esters processes for their preparation and pharmaceuticals containing these compounds ZA957877B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4433374A DE4433374A1 (de)	1994-09-20	1994-09-20	17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number	Publication Date
ZA957877B true ZA957877B (en)	1996-04-03

Family

ID=6528610

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA957877A ZA957877B (en)	1994-09-20	1995-09-19	17-deoxycorticosteroid-21-/O/-carboxylic esters processes for their preparation and pharmaceuticals containing these compounds

Country Status (24)

Country	Link
US (1)	US5824670A (da)
EP (1)	EP0708111B1 (da)
JP (1)	JP3902255B2 (da)
KR (1)	KR100406627B1 (da)
CN (1)	CN1056151C (da)
AT (1)	ATE188480T1 (da)
AU (1)	AU695710B2 (da)
CA (1)	CA2158610C (da)
CZ (1)	CZ288297B6 (da)
DE (2)	DE4433374A1 (da)
DK (1)	DK0708111T3 (da)
ES (1)	ES2140596T3 (da)
FI (1)	FI114708B (da)
GR (1)	GR3032688T3 (da)
HU (1)	HU217438B (da)
IL (1)	IL115331A (da)
NO (1)	NO305210B1 (da)
NZ (1)	NZ280038A (da)
PL (1)	PL186071B1 (da)
PT (1)	PT708111E (da)
RU (1)	RU2161624C2 (da)
SI (1)	SI9500295B (da)
TW (1)	TW424094B (da)
ZA (1)	ZA957877B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2180216C2 (ru) *	2000-03-13	2002-03-10	Открытое акционерное общество "Биосинтез"	Препарат, обладающий антимикробным и регенерирующим действием
WO2012011106A1 (en) *	2010-07-20	2012-01-26	Taro Pharmaceutical Industries Ltd.	Process for the preparation of 17-desoxy-corticosteroids
US12209988B2 (en)	2019-05-24	2025-01-28	Electronics And Telecommunications Research Institute	Sensor and method of manufacturing the same

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2755292A (en) *	1952-01-21	1956-07-17	Organon Labor Ltd	Phenyl propionate of testosterone
US2783226A (en) *	1955-02-03	1957-02-26	Schering Corp	Esters of cortical hormones
ES229413A1 (es) *	1956-06-22	1956-11-01	Francisco Vismara S P A	UN PROCEDIMIENTO PARA LA PREPARACIoN DE COMPUESTOS ESTEROIDALES QUE CONTENGAN UN GRUPO CEToLICO EN LA CADENA LATERAL
DE1131668B (de) *	1959-07-16	1962-06-20	Leo Ab	Verfahren zur Herstellung von Estern von Corticosteroid-Hormonen
CH495969A (de) *	1965-11-09	1970-09-15	Schering Ag	Verfahren zur Herstellung neuer 21-Ester von 16a-Methyl-21-hydroxy- 1,4-steroiden
DE2047105C3 (de) *	1970-09-18	1979-02-15	Schering Ag, 1000 Berlin Und 4619 Bergkamen	17-Chlorsteroide und Verfahren zu ihrer Herstellung
US3956349A (en) *	1975-02-18	1976-05-11	Syntex (U.S.A.) Inc.	Process for preparing 3-enol ethers of 11β-hydroxy-Δ4 -pregnene-3-ones and derivatives thereof
FR2342738A1 (fr) *	1976-03-02	1977-09-30	Roussel Uclaf	Nouveaux derives halogenes de la serie du 16a-methyl pregnane
DE2617655C2 (de) *	1976-04-21	1984-11-08	F. Hoffmann-La Roche & Co Ag, Basel	Kortikoide, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE2645104C2 (de) *	1976-10-04	1986-04-24	Schering AG, 1000 Berlin und 4709 Bergkamen	11β-Hydroxy-1,4,8-pregnatrien-3,20-dion-Derivate und Verfahren zu ihrer Herstellung
FR2381065A2 (fr) *	1977-02-22	1978-09-15	Roussel Uclaf	Nouveaux derives halogenes de la serie du 16 a-methyl pregnane
US4086254A (en) *	1977-04-13	1978-04-25	The Upjohn Company	Photocleavable steroids
LU77457A1 (da) *	1977-05-31	1979-01-19
US4377573A (en) *	1978-01-06	1983-03-22	Leveen Harry H	Method of control of gastrointestinal bleeding
DE2817988A1 (de) *	1978-04-25	1979-11-08	Hoechst Ag	Corticoid 17-alkylcarbonate und verfahren zu deren herstellung
DE2920726A1 (de) *	1979-05-18	1980-11-27	Schering Ag	Neue kortikoide, ihre herstellung und verwendung
EP0039369B1 (en) *	1980-05-02	1983-06-15	Schering Corporation	Beclomethasone ester solvates, process for their preparation, and preparation of a formulation
CY1359A (en) *	1981-02-02	1987-08-07	Schering Corp	Aromatic heterocyclic esters of steroids, their preparation and pharmaceutical compositions containing them
SE8303031D0 (sv) *	1983-05-30	1983-05-30	Leo Ab	Improved steroid esters preparation
US4910191A (en) *	1988-06-28	1990-03-20	Merrell Dow Pharmaceuticals Inc.	19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors
US4920114A (en) *	1988-06-28	1990-04-24	Merrell Dow Pharmaceuticals Inc.	19-fluoro- or cyano-21-hydroxyprogesterone derivatives useful as 19-hydroxylase inhibitors
CA2038985C (en) *	1990-04-02	2002-10-15	Joseph P. Burkhart	Haloethyl-substituted steroidal enzyme inhibitors

1994
- 1994-09-20 DE DE4433374A patent/DE4433374A1/de not_active Withdrawn
1995
- 1995-09-08 TW TW084109384A patent/TW424094B/zh not_active IP Right Cessation
- 1995-09-15 ES ES95114511T patent/ES2140596T3/es not_active Expired - Lifetime
- 1995-09-15 DK DK95114511T patent/DK0708111T3/da active
- 1995-09-15 EP EP95114511A patent/EP0708111B1/de not_active Expired - Lifetime
- 1995-09-15 PT PT95114511T patent/PT708111E/pt unknown
- 1995-09-15 DE DE59507565T patent/DE59507565D1/de not_active Expired - Lifetime
- 1995-09-15 AT AT95114511T patent/ATE188480T1/de active
- 1995-09-18 IL IL11533195A patent/IL115331A/en not_active IP Right Cessation
- 1995-09-18 AU AU31728/95A patent/AU695710B2/en not_active Ceased
- 1995-09-18 FI FI954394A patent/FI114708B/fi not_active IP Right Cessation
- 1995-09-18 US US08/529,668 patent/US5824670A/en not_active Expired - Lifetime
- 1995-09-18 NZ NZ280038A patent/NZ280038A/en not_active IP Right Cessation
- 1995-09-18 CZ CZ19952425A patent/CZ288297B6/cs not_active IP Right Cessation
- 1995-09-18 CN CN95116294A patent/CN1056151C/zh not_active Expired - Fee Related
- 1995-09-19 NO NO953695A patent/NO305210B1/no not_active IP Right Cessation
- 1995-09-19 CA CA002158610A patent/CA2158610C/en not_active Expired - Fee Related
- 1995-09-19 RU RU95116371/04A patent/RU2161624C2/ru not_active IP Right Cessation
- 1995-09-19 ZA ZA957877A patent/ZA957877B/xx unknown
- 1995-09-19 HU HU9502735A patent/HU217438B/hu not_active IP Right Cessation
- 1995-09-19 JP JP23939895A patent/JP3902255B2/ja not_active Expired - Fee Related
- 1995-09-19 PL PL95310544A patent/PL186071B1/pl not_active IP Right Cessation
- 1995-09-20 KR KR1019950030850A patent/KR100406627B1/ko not_active Expired - Fee Related
- 1995-09-20 SI SI9500295A patent/SI9500295B/sl unknown
2000
- 2000-02-18 GR GR20000400386T patent/GR3032688T3/el unknown

Also Published As

Publication number	Publication date
SI9500295B (en)	2001-12-31
IL115331A0 (en)	1995-12-31
HUT72969A (en)	1996-06-28
JP3902255B2 (ja)	2007-04-04
FI954394L (fi)	1996-03-21
US5824670A (en)	1998-10-20
SI9500295A (en)	1996-04-30
AU695710B2 (en)	1998-08-20
PL186071B1 (pl)	2003-10-31
JPH0899992A (ja)	1996-04-16
GR3032688T3 (en)	2000-06-30
TW424094B (en)	2001-03-01
FI954394A0 (fi)	1995-09-18
IL115331A (en)	2002-07-25
CN1056151C (zh)	2000-09-06
KR960010681A (ko)	1996-04-20
NO953695D0 (no)	1995-09-19
NO953695L (no)	1996-03-21
NO305210B1 (no)	1999-04-19
KR100406627B1 (ko)	2004-02-19
AU3172895A (en)	1996-04-04
DE4433374A1 (de)	1996-03-21
CN1124250A (zh)	1996-06-12
NZ280038A (en)	1997-03-24
CA2158610A1 (en)	1996-03-21
ES2140596T3 (es)	2000-03-01
HU9502735D0 (en)	1995-11-28
FI114708B (fi)	2004-12-15
CA2158610C (en)	2007-07-17
PT708111E (pt)	2000-04-28
PL310544A1 (en)	1996-04-01
DK0708111T3 (da)	2000-06-13
CZ242595A3 (en)	1996-04-17
CZ288297B6 (en)	2001-05-16
EP0708111A1 (de)	1996-04-24
EP0708111B1 (de)	2000-01-05
ATE188480T1 (de)	2000-01-15
HU217438B (hu)	2000-01-28
RU2161624C2 (ru)	2001-01-10
DE59507565D1 (de)	2000-02-10

Publication	Publication Date	Title
IL90062A0 (en)	1989-12-15	Pyridonecarboxylic acid derivatives,their preparation and pharmaceutical compositions containing them
IE842524L (en)	1985-04-04	Cephalosporins and analogous carboxyalkenoic acid¹derivatives
FI933857A0 (fi)	1993-09-03	Kondenserade heterocykliska foereningar, deras framstaellning och anvaendning
DE3576690D1 (de)	1990-04-26	Pyrimidopyrimidinderivate, verfahren zu ihrer herstellung, diese enthaltende pharmazeutische zubereitungen und ihre verwendung als anti-allergische mittel.
ATE121739T1 (de)	1995-05-15	Discodermolideverbindungen, diese enthaltende zubereitungen, verfahren zu ihrer herstellung und deren verwendung.
IE821768L (en)	1983-01-24	Pyrrolidine derivatives
WO1991000082A1 (en)	1991-01-10	Antimicrobial polymeric bisbiguanides
IL115331A0 (en)	1995-12-31	Ú7-deoxycorticoseroid-21-(o)-carboxylic esters processes for their preparation and pharmaceuticals containing these compounds
AU4872793A (en)	1994-04-14	New ellipticine compounds, a process for their preparation and pharmaceutical compositions containing them
ATE168376T1 (de)	1998-08-15	Triazolopyridazin-derivate, ihre herstellung und verwendung
GR3000831T3 (en)	1991-11-15	Piperazine compounds, process for preparing them, pharmaceutical composition and use
EP0464728A3 (en)	1992-06-03	Liquid crystal copolymer compound, composition thereof, and polymeric liquid crystal device making use of these
ES8706128A1 (es)	1987-06-01	Un procedimiento para la preparacion de derivados de imidazol triciclicos
EP0299076A4 (en)	1991-01-09	5-hydroxyindole-3-carboxamide compound and medicinal use thereof
EP0461574A3 (en)	1992-03-25	Medicines containing 3,7-diazabicyclo(3,3,1)nonanes
ZA905650B (en)	1991-05-29	Method of treating diabetes mellitus
GB8728314D0 (en)	1988-01-06	New compositions of matter
EP0356765A3 (en)	1991-08-07	Carboxylic acid derivatives, their production and use
PT75981B (en)	1985-11-20	Process for the preparation of n,n-dissubstituted alkenamides and phenyl alkenamides
DE69008058D1 (de)	1994-05-19	Salze von Acrylsäure, Verfahren zu ihrer Herstellung, pharmazeutische Zusammensetzungen, die sie enthalten und deren Verwendung in der Medizin.
GR3000593T3 (en)	1991-07-31	Azaanthracene compounds
DE59105961D1 (de)	1995-08-17	2,13-disubstituierte ergoline, deren herstellung und verwendung in arzneimitteln.