ZA972374B - Bis alkanoyl esters of carnitine having bactericidal, fungicidal and antiprotozoal activity. - Google Patents

Bis alkanoyl esters of carnitine having bactericidal, fungicidal and antiprotozoal activity.

Info

Publication number: ZA972374B
Authority: ZA; South Africa
Prior art keywords: fungicidal; carnitine; bactericidal; bis; straight
Prior art date: 1996-03-20

Application number

ZA9702374A

Other languages

English (en)

Inventor

Nazareno Scafetta

Maria Ornella Tinti

Francesco De Angelis

Gian Carlo Gramiccioli

Original Assignee

Sigma Tau Ind Farmaceuti

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-03-20

Filing date

1997-03-19

Publication date

1997-10-20

1997-03-19 Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti

1997-10-20 Publication of ZA972374B publication Critical patent/ZA972374B/xx

Links

230000000844 anti-bacterial effect Effects 0.000 title abstract 2
230000000855 fungicidal effect Effects 0.000 title abstract 2
PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 title 1
230000000842 anti-protozoal effect Effects 0.000 title 1
125000001589 carboacyl group Chemical group 0.000 title 1
229960004203 carnitine Drugs 0.000 title 1
125000004432 carbon atom Chemical group C* 0.000 abstract 2
PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical class C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
150000001450 anions Chemical class 0.000 abstract 1
210000000883 ear external Anatomy 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
210000004877 mucosa Anatomy 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1
210000003491 skin Anatomy 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Dermatology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA9702374A 1996-03-20 1997-03-19 Bis alkanoyl esters of carnitine having bactericidal, fungicidal and antiprotozoal activity. ZA972374B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT96RM000180A IT1283955B1 (it)	1996-03-20	1996-03-20	Bis alcanoil esteri della carnitina ad attivita' antibatterica, antimicotica ed antiprotozoaria.

Publications (1)

Publication Number	Publication Date
ZA972374B true ZA972374B (en)	1997-10-20

Family

ID=11404010

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA9702374A ZA972374B (en)	1996-03-20	1997-03-19	Bis alkanoyl esters of carnitine having bactericidal, fungicidal and antiprotozoal activity.

Country Status (14)

Country	Link
US (1)	US5925369A (da)
EP (1)	EP0796841B1 (da)
JP (1)	JP4077052B2 (da)
KR (1)	KR100491099B1 (da)
AT (1)	ATE193521T1 (da)
CA (1)	CA2200409C (da)
DE (1)	DE69702158T2 (da)
DK (1)	DK0796841T3 (da)
ES (1)	ES2147663T3 (da)
GR (1)	GR3034243T3 (da)
IT (1)	IT1283955B1 (da)
PT (1)	PT796841E (da)
TW (1)	TW491828B (da)
ZA (1)	ZA972374B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1306129B1 (it) *	1999-04-13	2001-05-30	Sigma Tau Ind Farmaceuti	Esteri della l-carnitina o di alcanoil l-carnitine utilizzabili comelipidi cationici per l'immissione intracellulare di composti
BRPI0712600B1 (pt)	2006-05-19	2015-10-27	Mary Kay Inc	composição tópica para cuidados com a pele e método para a esfoliação da pele.
EP2967045B1 (en)	2013-03-12	2019-06-26	Mary Kay, Inc.	Preservative system
CN105017045B (zh) *	2015-06-09	2017-11-07	中北大学	一种连接基含双酯基的双季铵盐及其作为杀菌剂的应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2497673A (en) *	1946-04-16	1950-02-14	Du Pont	Reaction of alpha-beta unsaturated compounds with aromatic hydrocarbons and products obtained
US2712025A (en) *	1951-09-26	1955-06-28	Chessie E Rehberg	Production of dicarboxylic acid esters of alpha-hydroxycarboxylic acid esters
IT1201481B (it) *	1985-10-08	1989-02-02	Prodotti Antibiotici Spa	Pantotenil derivati
IT1254136B (it) *	1992-01-16	1995-09-08	Sigma Tau Ind Farmaceuti	Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antimicotica.
IT1254135B (it) *	1992-01-16	1995-09-08	Sigma Tau Ind Farmaceuti	Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica.
EP0647133A4 (en) *	1992-06-12	1997-10-29	Affymax Tech Nv	COMPOSITIONS AND METHODS FOR IMPROVED DRUG DELIVERY.

1996
- 1996-03-20 IT IT96RM000180A patent/IT1283955B1/it active IP Right Grant
1997
- 1997-03-10 TW TW086103027A patent/TW491828B/zh not_active IP Right Cessation
- 1997-03-14 EP EP97830118A patent/EP0796841B1/en not_active Expired - Lifetime
- 1997-03-14 US US08/818,737 patent/US5925369A/en not_active Expired - Fee Related
- 1997-03-14 AT AT97830118T patent/ATE193521T1/de not_active IP Right Cessation
- 1997-03-14 PT PT97830118T patent/PT796841E/pt unknown
- 1997-03-14 ES ES97830118T patent/ES2147663T3/es not_active Expired - Lifetime
- 1997-03-14 DE DE69702158T patent/DE69702158T2/de not_active Expired - Lifetime
- 1997-03-14 DK DK97830118T patent/DK0796841T3/da active
- 1997-03-19 CA CA002200409A patent/CA2200409C/en not_active Expired - Fee Related
- 1997-03-19 ZA ZA9702374A patent/ZA972374B/xx unknown
- 1997-03-20 KR KR1019970009443A patent/KR100491099B1/ko not_active Expired - Fee Related
- 1997-03-21 JP JP06784297A patent/JP4077052B2/ja not_active Expired - Fee Related
2000
- 2000-08-23 GR GR20000401930T patent/GR3034243T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
PT796841E (pt)	2000-09-29
ITRM960180A0 (da)	1996-03-20
US5925369A (en)	1999-07-20
ATE193521T1 (de)	2000-06-15
CA2200409C (en)	2006-11-28
GR3034243T3 (en)	2000-12-29
EP0796841A1 (en)	1997-09-24
ES2147663T3 (es)	2000-09-16
DE69702158D1 (de)	2000-07-06
KR970065506A (ko)	1997-10-13
MX9702043A (es)	1998-03-31
KR100491099B1 (ko)	2006-01-12
CA2200409A1 (en)	1997-09-20
EP0796841B1 (en)	2000-05-31
ITRM960180A1 (it)	1997-09-20
DK0796841T3 (da)	2000-11-13
TW491828B (en)	2002-06-21
JPH107631A (ja)	1998-01-13
JP4077052B2 (ja)	2008-04-16
IT1283955B1 (it)	1998-05-07
DE69702158T2 (de)	2000-10-19

Publication	Publication Date	Title
AU4541689A (en)	1990-06-07	Quinazolinonederivatives which are bronchodilators and vasodilators
ATE252385T1 (de)	2003-11-15	Vorbeugende oder heilende mittel für krankheiten, die durch mangel an stickoxid-synthase (nos) ausgelöst sind
BG101250A (en)	1997-09-30	Salts of an anti-migraine indole derivative
HU9401515D0 (en)	1994-08-29	New polypeptide compound and a process for prepation thereof
GR3005990T3 (da)	1993-06-07
NZ228216A (en)	1991-01-29	Tetrahydroimidazo(4,5,1-jk)(1,4)benzodiazepinone derivatives and antiviral compositions
DE3363550D1 (en)	1986-06-19	New nitro aliphatic compounds, process for preparation thereof and use thereof
GR3034243T3 (en)	2000-12-29	Bis alkanoyl esters of carnitine having bactericidal, fungicidal and antiprotozoal activity
EP0181592A3 (en)	1990-08-29	Use of spergualin derivatives for the preparation of medicaments having immunosuppressive activity
ITRM910327A1 (it)	1992-11-15	Uso di esteri di acil l-carnitine con l'acido gamma-idrossibutirrico per produrre composizioni farmaceutiche per il trattamento di epatopatie
AU7266291A (en)	1991-09-12	A novel substituted-amine compound and a process for the preparation thereof
GR871549B (en)	1988-02-12	Amino acid derivative anticonvulsant
ES2000681A6 (es)	1988-03-16	Un procedimiento para preparar nuevos compuestos de bencilpiperazina
DE69203164D1 (de)	1995-08-03	Vorbeugende/therapeutische Zusammensetzung für die Pleuropneumonie des Schweins.
GR3031709T3 (en)	2000-02-29	Octahydro-2-naphthalenecarboxylic acid derivative, its production and use.
AU8705198A (en)	1998-09-08	Remedies/preventives for respiratory diseases
IL103202A0 (en)	1993-02-21	Method for treating hypertension
AU7020996A (en)	1997-04-24	UCK14 compounds
GR3024743T3 (en)	1997-12-31	Cephem compounds with antimicrobial activity.
EP0450232A3 (en)	1992-01-22	P-guanidino benzoic acid derivatives for treatment of cerebrovascular contraction
GR852126B (da)	1986-01-03
AU7993982A (en)	1982-08-05	Tetra-peptide
ES8301230A1 (es)	1982-12-01	Un procedimiento para la preparacion de 1-fenil-5-amidotetrazoles.