ZA974470B - Hexahydro-pyrido[4,3-b]indole derivatives - Google Patents

Hexahydro-pyrido[4,3-b]indole derivatives

Info

Publication number
ZA974470B
ZA974470B ZA974470A ZA974470A ZA974470B ZA 974470 B ZA974470 B ZA 974470B ZA 974470 A ZA974470 A ZA 974470A ZA 974470 A ZA974470 A ZA 974470A ZA 974470 B ZA974470 B ZA 974470B
Authority
ZA
South Africa
Prior art keywords
6alkyl
hydrogen
pct
formula
date nov
Prior art date
Application number
ZA974470A
Other languages
English (en)
Inventor
Ludo Edmond Josephine Kennis
Josephus Carolus Mertens
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZA974470B publication Critical patent/ZA974470B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA974470A 1996-05-23 1997-05-22 Hexahydro-pyrido[4,3-b]indole derivatives ZA974470B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96201450 1996-05-23

Publications (1)

Publication Number Publication Date
ZA974470B true ZA974470B (en) 1998-11-23

Family

ID=8224021

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA974470A ZA974470B (en) 1996-05-23 1997-05-22 Hexahydro-pyrido[4,3-b]indole derivatives

Country Status (22)

Country Link
US (1) US6057325A (de)
EP (1) EP0902684B1 (de)
JP (1) JP2000510860A (de)
CN (1) CN1149996C (de)
AT (1) ATE236636T1 (de)
AU (1) AU714113B2 (de)
CA (1) CA2254755C (de)
CY (1) CY2381B1 (de)
CZ (1) CZ287961B6 (de)
DE (1) DE69720715T2 (de)
DK (1) DK0902684T3 (de)
ES (1) ES2196332T3 (de)
IL (1) IL127177A (de)
MY (1) MY125562A (de)
NO (1) NO311724B1 (de)
NZ (1) NZ332310A (de)
PL (1) PL187345B1 (de)
PT (1) PT902684E (de)
SI (1) SI0902684T1 (de)
TW (1) TW470745B (de)
WO (1) WO1997044040A1 (de)
ZA (1) ZA974470B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1136493A1 (de) * 2000-03-23 2001-09-26 Sanofi-Synthelabo 2-(Thienopyridinyl)pyrimidon-, 2-(Furopyridinyl)pyrimidon-2-(isoquinolinyl)pyrimidon-, 2-(Pyridoindolyl)pyrimidon- und 2-(Benzofuropyridinyl)pyrimidonderivate
US6849640B2 (en) 2001-08-08 2005-02-01 Pharmacia & Upjohn Company Therapeutic 1H-pyrido [4,3-b] indoles
WO2004056324A2 (en) * 2002-12-19 2004-07-08 Bristol-Myers Squibb Company Substituted tricyclic gamma-carbolines as serotonin receptor agonists and antagonists
EP1944306A1 (de) * 2003-09-17 2008-07-16 Janssen Pharmaceutica, N.V. Fusionierte heterocyclische Verbindungen
SG146683A1 (en) * 2003-09-17 2008-10-30 Janssen Pharmaceutica Nv Fused heterocyclic compounds as serotonin receptor modulators
UA85563C2 (ru) * 2003-09-17 2009-02-10 Янссен Фармацевтика Н.В. Конденсированные гетероциклические соединения
KR101168611B1 (ko) 2003-09-17 2012-08-03 얀센 파마슈티카 엔.브이. 세로토닌 수용체 조절자로서의 융합된 헤테로사이클릭 화합물
RU2338537C2 (ru) * 2006-01-25 2008-11-20 Сергей Олегович Бачурин СРЕДСТВО ДЛЯ ЛЕЧЕНИЯ ШИЗОФРЕНИИ НА ОСНОВЕ ГИДРИРОВАННЫХ ПИРИДО(4,3-b)ИНДОЛОВ (ВАРИАНТЫ), ФАРМАКОЛОГИЧЕСКОЕ СРЕДСТВО НА ЕГО ОСНОВЕ И СПОСОБ ЕГО ПРИМЕНЕНИЯ
CA2719824A1 (en) * 2007-08-01 2009-02-05 Medivation Neurology, Inc. Methods and compositions for treating schizophrenia using antipsychotic combination therapy
AR073923A1 (es) * 2008-10-31 2010-12-09 Medivation Technologies Inc Pirido( 4,3-b) indoles que contienen restos rigidos
CN102316732B (zh) 2008-10-31 2015-04-01 梅迪维新技术公司 氮杂*并[4,5-b]吲哚以及使用方法
CA2829045A1 (en) 2011-02-18 2012-08-23 Medivation Technologies, Inc. Compounds and methods for treatment of hypertension
WO2014031167A1 (en) * 2012-08-22 2014-02-27 Medivation Technologies, Inc. Compounds and methods for treatment of hypertension
CN122404328A (zh) * 2024-05-31 2026-07-17 和径医药科技（上海）有限公司 三并环类化合物、其药物组合物及应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205452A1 (es) * 1973-12-06 1976-05-07 Endo Lab Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles
US4337250A (en) * 1979-07-30 1982-06-29 Pfizer Inc. Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents

Also Published As

Publication number Publication date
EP0902684B1 (de) 2003-04-09
CZ377498A3 (cs) 1999-02-17
PL330079A1 (en) 1999-04-26
NZ332310A (en) 1999-08-30
CN1149996C (zh) 2004-05-19
ATE236636T1 (de) 2003-04-15
JP2000510860A (ja) 2000-08-22
SI0902684T1 (en) 2003-10-31
PT902684E (pt) 2003-08-29
EP0902684A1 (de) 1999-03-24
CA2254755C (en) 2007-01-16
CZ287961B6 (cs) 2001-03-14
WO1997044040A1 (en) 1997-11-27
AU2961697A (en) 1997-12-09
CN1219875A (zh) 1999-06-16
DK0902684T3 (da) 2004-03-29
NO985389L (no) 1999-01-20
AU714113B2 (en) 1999-12-16
IL127177A0 (en) 1999-09-22
CY2381B1 (en) 2004-06-04
TW470745B (en) 2002-01-01
PL187345B1 (pl) 2004-06-30
US6057325A (en) 2000-05-02
IL127177A (en) 2003-10-31
MY125562A (en) 2006-08-30
DE69720715D1 (en) 2003-05-15
CA2254755A1 (en) 1997-11-27
ES2196332T3 (es) 2003-12-16
DE69720715T2 (de) 2004-03-11
NO311724B1 (no) 2002-01-14
NO985389D0 (no) 1998-11-19

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